Ink4/Arf locus restores glucose tolerance and insulin sensitivity by reducing hepatic steatosis and inflammation in mice with impaired IRS2-dependent signalling

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 9, 2015, Pages 1729-1742

  Vinue Angela ^a   Andrés Blasco, Irene ^a   Herrero Cervera, Andrea ^a   Piqueras, Laura ^a   Andrés, Vicente ^b   Burks, Deborah J ^c,d   Sanz, María Jesús ^a,e   González Navarro, Herminia ^a,d  

^a Instituto Universitario IVI INCLIVA   (Spain)

^b CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^c CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^d INSTITUTO DE SALUD CARLOS III   (Spain)

^e UNIVERSITY OF VALENCIA   (Spain)

Author keywords

CDKN2A 2B; Diabetes; Inflammation; Insulin resistance; Macrophage; Steatosis

Indexed keywords

INSULIN; INSULIN RECEPTOR SUBSTRATE 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FATTY LIVER; GENE LOCUS; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; IN VIVO STUDY; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; LYMPHOCYTE ACTIVATION; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; WILD TYPE;

MUS;

EID: 84930680495     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2015.05.013     Document Type: Article

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