-
1
-
-
0026554640
-
Molecular physiology and genetics of NIDDM. Importance of metabolic staging
-
Granner, D.K., and R.M. O'Brien. 1992. Molecular physiology and genetics of NIDDM. Importance of metabolic staging. Diabetes Care. 15:369-396.
-
(1992)
Diabetes Care
, vol.15
, pp. 369-396
-
-
Granner, D.K.1
O'Brien, R.M.2
-
2
-
-
0027973609
-
The genetics of NIDDM. An update
-
Elbein, S.C., M.D. Hoffman, K.L. Bragg, and R.A. Mayorga. 1994. The genetics of NIDDM. An update. Diabetes Care. 17:1523-1533.
-
(1994)
Diabetes Care
, vol.17
, pp. 1523-1533
-
-
Elbein, S.C.1
Hoffman, M.D.2
Bragg, K.L.3
Mayorga, R.A.4
-
4
-
-
9044243415
-
A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2
-
Hanis, C.L., E. Boerwinkle, R. Chakraborty, D.L. Ellsworth, P. Concannon, B. Stirling, V.A. Morrison, B. Wapelhorst, R.S. Spielman, K.J. Gogolin-Ewens, et al. 1996. A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nat. Genet. 13:161-166.
-
(1996)
Nat. Genet.
, vol.13
, pp. 161-166
-
-
Hanis, C.L.1
Boerwinkle, E.2
Chakraborty, R.3
Ellsworth, D.L.4
Concannon, P.5
Stirling, B.6
Morrison, V.A.7
Wapelhorst, B.8
Spielman, R.S.9
Gogolin-Ewens, K.J.10
-
5
-
-
15844429514
-
Evidence for a major gene for type II diabetes and linkage analysis with selected candidate genes in Mexican-Americans
-
Stern, M.P., B.D. Mitchell, J. Blangero, L. Reinhart, C.M. Kammerer, C.R. Harrison, P.A. Shipman, P. O'Connell, M.L. Frazier, and J.W. MacCluer. 1996. Evidence for a major gene for type II diabetes and linkage analysis with selected candidate genes in Mexican-Americans. Diabetes. 45:563-568.
-
(1996)
Diabetes
, vol.45
, pp. 563-568
-
-
Stern, M.P.1
Mitchell, B.D.2
Blangero, J.3
Reinhart, L.4
Kammerer, C.M.5
Harrison, C.R.6
Shipman, P.A.7
O'Connell, P.8
Frazier, M.L.9
MacCluer, J.W.10
-
6
-
-
0029045390
-
Segregation analysis of non-insulin-dependent diabetes mellitus in Pima Indians: Evidence for a major gene effect
-
Hanson, R.L., R.C. Elston, D.J. Pettitt, P.H. Bennett, and W.C. Knowler. 1995. Segregation analysis of non-insulin-dependent diabetes mellitus in Pima Indians: evidence for a major gene effect. Am. J. Hum. Genetics. 57:160-170.
-
(1995)
Am. J. Hum. Genetics
, vol.57
, pp. 160-170
-
-
Hanson, R.L.1
Elston, R.C.2
Pettitt, D.J.3
Bennett, P.H.4
Knowler, W.C.5
-
7
-
-
0031017322
-
A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2
-
Comuzzie, A.G., J.E. Hixson, L. Almasy, B.D. Mitchell, M.C. Mahaney, T.D. Dyer, M.P. Stern, J.W. MacCluer, and J. Blangero. 1997. A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2. Nat. Genet. 15:273-276.
-
(1997)
Nat. Genet.
, vol.15
, pp. 273-276
-
-
Comuzzie, A.G.1
Hixson, J.E.2
Almasy, L.3
Mitchell, B.D.4
Mahaney, M.C.5
Dyer, T.D.6
Stern, M.P.7
MacCluer, J.W.8
Blangero, J.9
-
8
-
-
0027459878
-
Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance
-
Hotamisligil, G.S., N.S. Shargill, and B.M. Spiegelman. 1993. Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science. 259:87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
9
-
-
0028031569
-
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central Role of Tumor Necrosis Factor-α
-
Hotamisligil, G.S., A. Budavari, D. Murray, and B.M. Spiegelman. 1994. Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-α. J. Clin. In vest. 94:1543-1549.
-
(1994)
J. Clin. in Vest.
, vol.94
, pp. 1543-1549
-
-
Hotamisligil, G.S.1
Budavari, A.2
Murray, D.3
Spiegelman, B.M.4
-
10
-
-
0028362194
-
Tumor necrosis factor-α inhibits signaling from the insulin receptor
-
Hotamisligil, G.S., D.L. Murray, L.N. Choy, and B.M. Spiegelman. 1994. Tumor necrosis factor-α inhibits signaling from the insulin receptor. Proc: Natl. Acad. Sci. USA. 91:4854-4858.
-
(1994)
Proc: Natl. Acad. Sci. USA
, vol.91
, pp. 4854-4858
-
-
Hotamisligil, G.S.1
Murray, D.L.2
Choy, L.N.3
Spiegelman, B.M.4
-
11
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance
-
Hotamisligil, G.S., P. Arner, J.F. Caro, R.L. Atkinson, and B.M. Spiegelman. 1995. Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J. Clin. Invest. 95:2409-2415.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
12
-
-
0030028606
-
The expression of TNF-α by human muscle. Relationship to insulin resistance
-
Saghizadeh, M., J.M. Ong, W.T. Garvey, R.R. Henry, and P.A. Kern. 1996. The expression of TNF-α by human muscle. Relationship to insulin resistance. J. Clin. Invest. 97:1111-1116.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1111-1116
-
-
Saghizadeh, M.1
Ong, J.M.2
Garvey, W.T.3
Henry, R.R.4
Kern, P.A.5
-
13
-
-
0030611101
-
Potential role of TNF-α and lipoprotein lipase as candidate genes for obesity
-
Kern, P.A. 1997. Potential role of TNF-α and lipoprotein lipase as candidate genes for obesity. J. Nutr. 127:1917S-1922S.
-
(1997)
J. Nutr.
, vol.127
-
-
Kern, P.A.1
-
14
-
-
0028968879
-
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
-
Kern, P.A., M. Saghizadeh, J.M. Ong, R.J. Bosch, R. Deem, and R.B. Simsolo. 1995. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J. Clin. Invest. 95:2111-2119.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 2111-2119
-
-
Kern, P.A.1
Saghizadeh, M.2
Ong, J.M.3
Bosch, R.J.4
Deem, R.5
Simsolo, R.B.6
-
15
-
-
0027972524
-
Altered gene expression for tumor necrosis factor-α and its receptors during drug and dietary modulation of insulin resistance
-
Hofmann, C., K. Lorenz, S.S. Braithwaite, J.R. Colca, B.J. Palazuk, G.S. Hotamisligil, and B.M. Spiegelman. 1994. Altered gene expression for tumor necrosis factor-α and its receptors during drug and dietary modulation of insulin resistance. Endocrinology. 134:264-270.
-
(1994)
Endocrinology
, vol.134
, pp. 264-270
-
-
Hofmann, C.1
Lorenz, K.2
Braithwaite, S.S.3
Colca, J.R.4
Palazuk, B.J.5
Hotamisligil, G.S.6
Spiegelman, B.M.7
-
16
-
-
0029906375
-
Effects of an engineered human anti-TNF-α antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM
-
Ofei, F., S. Hurel, J. Newkirk, M. Sopwith, and R. Taylor. 1996. Effects of an engineered human anti-TNF-α antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM. Diabetes. 45:881-885.
-
(1996)
Diabetes
, vol.45
, pp. 881-885
-
-
Ofei, F.1
Hurel, S.2
Newkirk, J.3
Sopwith, M.4
Taylor, R.5
-
17
-
-
0029948098
-
Effect of tumor necrosis factor-α on insulin action in cultured rat skeletal muscle cells
-
Begum, N., and L. Ragolia. 1996. Effect of tumor necrosis factor-α on insulin action in cultured rat skeletal muscle cells. Endocrinology. 137:2441-2446.
-
(1996)
Endocrinology
, vol.137
, pp. 2441-2446
-
-
Begum, N.1
Ragolia, L.2
-
18
-
-
0026549669
-
Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output
-
Lang, C.H., C. Dobrescu, and G.J. Bagby. 1992. Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output. Endocrinology. 130:43-52.
-
(1992)
Endocrinology
, vol.130
, pp. 43-52
-
-
Lang, C.H.1
Dobrescu, C.2
Bagby, G.J.3
-
19
-
-
0028267977
-
Effects of tumor necrosis factor-α on glucose and albumin production in primary cultures of rat hepatocytes
-
Dahn, M.S., C.J. Hsu, P.P. Lange, and L.S. Jefferson. 1994. Effects of tumor necrosis factor-α on glucose and albumin production in primary cultures of rat hepatocytes. Metabolism. 43:476-480.
-
(1994)
Metabolism
, vol.43
, pp. 476-480
-
-
Dahn, M.S.1
Hsu, C.J.2
Lange, P.P.3
Jefferson, L.S.4
-
20
-
-
0029417129
-
TNF-α inhibits glucose-induced insulin secretion in a pancreatic β cell line (INS-1)
-
Zhang, S., and K. Kim. 1995. TNF-α inhibits glucose-induced insulin secretion in a pancreatic β cell line (INS-1). FEBS Lett. 377:237-239.
-
(1995)
FEBS Lett.
, vol.377
, pp. 237-239
-
-
Zhang, S.1
Kim, K.2
-
21
-
-
0028326491
-
Effect of cytokines on insulin release and glucose oxidation by cultured human islets of ventral and dorsal origin
-
Vara, E., J. Arias-Diaz, C. Garcia, and J.L. Balibrea. 1994. Effect of cytokines on insulin release and glucose oxidation by cultured human islets of ventral and dorsal origin. Transplant. Proc. 26:695-697.
-
(1994)
Transplant. Proc.
, vol.26
, pp. 695-697
-
-
Vara, E.1
Arias-Diaz, J.2
Garcia, C.3
Balibrea, J.L.4
-
22
-
-
0023784346
-
IFN-γ and tumor necrosis factor-α. Cytotoxicity to murine islets of Langerhans
-
Campbell, I.L., A. Iscaro, and L.C. Harrison. 1988. IFN-γ and tumor necrosis factor-α. Cytotoxicity to murine islets of Langerhans. J. Immunol. 141: 2325-2329.
-
(1988)
J. Immunol.
, vol.141
, pp. 2325-2329
-
-
Campbell, I.L.1
Iscaro, A.2
Harrison, L.C.3
-
23
-
-
0028587742
-
Tumor necrosis factor-α: A key component of the obesity-diabetes link
-
Hotamisligil, G.S., and B.M. Spiegelman. 1994. Tumor necrosis factor-α: a key component of the obesity-diabetes link. Diabetes. 43:1271-1278.
-
(1994)
Diabetes
, vol.43
, pp. 1271-1278
-
-
Hotamisligil, G.S.1
Spiegelman, B.M.2
-
24
-
-
0026072837
-
The two different receptors for tumor necrosis factor mediate distinct cellular responses
-
Tartaglia, L.A., R.F. Weber, I.S. Figari, C. Reynolds, M.A. Palladino, Jr., and D.V. Goeddel. 1991. The two different receptors for tumor necrosis factor mediate distinct cellular responses. Proc. Natl. Acad. Sci. USA. 88:9292-9296.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 9292-9296
-
-
Tartaglia, L.A.1
Weber, R.F.2
Figari, I.S.3
Reynolds, C.4
Palladino Jr., M.A.5
Goeddel, D.V.6
-
25
-
-
0027297663
-
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
-
Pfeffer, K., T. Matsuyama, T.M. Kundig, J.A. Wakeham, K. Kishihara, A. Shahinian, K. Wiegmann, P.S. Ohashi, M. Kronke, and T.W. Mak. 1993. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell. 73:457-467.
-
(1993)
Cell
, vol.73
, pp. 457-467
-
-
Pfeffer, K.1
Matsuyama, T.2
Kundig, T.M.3
Wakeham, J.A.4
Kishihara, K.5
Shahinian, A.6
Wiegmann, K.7
Ohashi, P.S.8
Kronke, M.9
Mak, T.W.10
-
26
-
-
0027327619
-
Mice lacking the tumour necrosis factor receptor I are resistant Io TNF-mediated toxicity but highly susceptible to infection by Lysteria monocytogenes
-
Rothe, J., W. Lesslauer, H. Lotscher, Y. Lang, P. Koebel, F. Kontgen, A. Althage, R. Zinkernagel, M. Steinmetz, and H. Bluethmann. 1993. Mice lacking the tumour necrosis factor receptor I are resistant Io TNF-mediated toxicity but highly susceptible to infection by Lysteria monocytogenes. Nature. 364:798-802.
-
(1993)
Nature
, vol.364
, pp. 798-802
-
-
Rothe, J.1
Lesslauer, W.2
Lotscher, H.3
Lang, Y.4
Koebel, P.5
Kontgen, F.6
Althage, A.7
Zinkernagel, R.8
Steinmetz, M.9
Bluethmann, H.10
-
27
-
-
0028149960
-
Differential responses of fibroblasts from wild-type and TNF-P55-deficient mice to mouse and human TNF-α activation
-
Mackay, F., J. Rothe, H. Bluethmann, H. Loetscher, and W. Lesslauer. 1994. Differential responses of fibroblasts from wild-type and TNF-P55-deficient mice to mouse and human TNF-α activation. J. Immunol. 153:5274-5284.
-
(1994)
J. Immunol.
, vol.153
, pp. 5274-5284
-
-
Mackay, F.1
Rothe, J.2
Bluethmann, H.3
Loetscher, H.4
Lesslauer, W.5
-
28
-
-
0028063303
-
Decreased sensitivity to tumor necrosis factor but normal T cell development in TNF receptor-2-deficient mice
-
Erickson, S.L., F.J. de Sauvage, K. Kikly, K. Carver-Moore, S. Pitts-Meek, N. Gillett, K.C. Sheehan, R.D. Schreiber, D.V. Goeddel, and M.W. Moore. 1994. Decreased sensitivity to tumor necrosis factor but normal T cell development in TNF receptor-2-deficient mice. Nature. 372:560-563.
-
(1994)
Nature
, vol.372
, pp. 560-563
-
-
Erickson, S.L.1
De Sauvage, F.J.2
Kikly, K.3
Carver-Moore, K.4
Pitts-Meek, S.5
Gillett, N.6
Sheehan, K.C.7
Schreiber, R.D.8
Goeddel, D.V.9
Moore, M.W.10
-
29
-
-
0031900951
-
The role of tumor necrosis factor-α receptors in atherosclerosis
-
LeBoeuf, R.C., and S.A. Schreyer. 1998. The role of tumor necrosis factor-α receptors in atherosclerosis. Trends Cardiovasc. Med. 8:131-138.
-
(1998)
Trends Cardiovasc. Med.
, vol.8
, pp. 131-138
-
-
Leboeuf, R.C.1
Schreyer, S.A.2
-
30
-
-
0028987633
-
Tumor necrosis factor-α eliminates binding of NF-Y and an octamer binding protein to the lipoprotein lipase promoter in 3T3-L1 adipocytes
-
Morin, C.L., I.R. Schlaepfer, and R.H. Eckel. 1995. Tumor necrosis factor-α eliminates binding of NF-Y and an octamer binding protein to the lipoprotein lipase promoter in 3T3-L1 adipocytes. J. Clin. Invest. 95:1684-1689.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 1684-1689
-
-
Morin, C.L.1
Schlaepfer, I.R.2
Eckel, R.H.3
-
31
-
-
0029933665
-
Tumor necrosis factor (TNF)-α inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase
-
Peraldi, P., G.S. Hotamisligil, W.A. Buurman, M.F. White, and B.M. Speigelman. 1996. Tumor necrosis factor (TNF)-α inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase. J. Biol. Chem. 271:13018-13022.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13018-13022
-
-
Peraldi, P.1
Hotamisligil, G.S.2
Buurman, W.A.3
White, M.F.4
Speigelman, B.M.5
-
32
-
-
0031053823
-
Differential regulation of the p80 tumor necrosis factor receptor in human obesity and insulin resistance
-
Hotamisligil, G.S., P. Arner, R.L. Atkinson, and B.M. Spiegelman. 1997. Differential regulation of the p80 tumor necrosis factor receptor in human obesity and insulin resistance. Diabetes. 46:451-155.
-
(1997)
Diabetes
, vol.46
, pp. 451-1155
-
-
Hotamisligil, G.S.1
Arner, P.2
Atkinson, R.L.3
Spiegelman, B.M.4
-
33
-
-
0030864185
-
Targeted disruption of the tumor necrosis factor-α gene: Metabolic consequences in obese and nonobese mice
-
Ventre, J., T. Doebber, M. Wu, K. MacNaul, K. Stevens, M. Pasparakis, G. Kollias, and D.E. Moller. 1997. Targeted disruption of the tumor necrosis factor-α gene: metabolic consequences in obese and nonobese mice. Diabetes. 46:1526-1531.
-
(1997)
Diabetes
, vol.46
, pp. 1526-1531
-
-
Ventre, J.1
Doebber, T.2
Wu, M.3
MacNaul, K.4
Stevens, K.5
Pasparakis, M.6
Kollias, G.7
Moller, D.E.8
-
34
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-α function
-
Uysal, K.T., S.M. Wiesbrock, M.W. Marino, and G.S. Hotamisligil. 1997. Protection from obesity-induced insulin resistance in mice lacking TNF-α function. Nature. 389:610-614.
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
35
-
-
0024229140
-
Diet-induced type II diabetes in C57BL/6J mice
-
Surwit, R.S., C.M. Kuhn, C. Cochrane, J.A. McCubbin, and M.N. Feinglos. 1988. Diet-induced type II diabetes in C57BL/6J mice. Diabetes. 37:1163-1167.
-
(1988)
Diabetes
, vol.37
, pp. 1163-1167
-
-
Surwit, R.S.1
Kuhn, C.M.2
Cochrane, C.3
McCubbin, J.A.4
Feinglos, M.N.5
-
36
-
-
0026025628
-
Control of expression of insulin resistance and hyperglycemia by different genetic factors in diabetic C57BL/6J mice
-
Surwit, R.S., M.F. Seldin, C.M. Kuhn, C. Cochrane, and M.N. Feinglos. 1991. Control of expression of insulin resistance and hyperglycemia by different genetic factors in diabetic C57BL/6J mice. Diabetes. 40:82-87.
-
(1991)
Diabetes
, vol.40
, pp. 82-87
-
-
Surwit, R.S.1
Seldin, M.F.2
Kuhn, C.M.3
Cochrane, C.4
Feinglos, M.N.5
-
37
-
-
0031985413
-
TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation
-
Peschon, J.P., D.S. Torrance, K.L. Stocking, M.B. Glaccum, C. Otten, C.R. Willis, K. Charrier, P.J. Morrissey, C.B. Ware, and D.M. Mohler. 1998. TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation. J. Immunol. 160:943-952.
-
(1998)
J. Immunol.
, vol.160
, pp. 943-952
-
-
Peschon, J.P.1
Torrance, D.S.2
Stocking, K.L.3
Glaccum, M.B.4
Otten, C.5
Willis, C.R.6
Charrier, K.7
Morrissey, P.J.8
Ware, C.B.9
Mohler, D.M.10
-
38
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen, H., O. Charlat, L.A. Tartaglia, E.A. Woolf, X. Weng, S.J. Ellis, N.D. Lakey, J. Culpepper, K.J. Moore, R.E. Breitbart, G.M. Duyk, R.I. Tepper, and J.P. Morgenstern. 1996. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell. 84:491-495.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breitbart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
39
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee, G.H., R. Proenca, J.M. Montez, K.M. Carroll, J.G. Darvishzadeh, J.I. Lee, J.M. Friedman. 1996. Abnormal splicing of the leptin receptor in diabetic mice. Nature. 379:632-635.
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
Friedman, J.M.7
-
40
-
-
0028140401
-
Regulation by nutritional status of lipids and apolipoproteins A-I, A-II, and A-IV in inbred mice
-
LeBoeuf, R.C., M. Caldwell, and E. Kirk. 1994. Regulation by nutritional status of lipids and apolipoproteins A-I, A-II, and A-IV in inbred mice. J. Lipid Res. 35:121-133.
-
(1994)
J. Lipid Res.
, vol.35
, pp. 121-133
-
-
LeBoeuf, R.C.1
Caldwell, M.2
Kirk, E.3
-
41
-
-
0030853681
-
Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase
-
Jensen, D.R., I.R. Schlaepfer, C.L. Morin, D.S. Pennington, T. Marcell, S.M. Ammon, H.A. Gutierrez, and R.H. Eckel. 1997. Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase. Am. J. Physiol. 273:R683-689.
-
(1997)
Am. J. Physiol.
, vol.273
-
-
Jensen, D.R.1
Schlaepfer, I.R.2
Morin, C.L.3
Pennington, D.S.4
Marcell, T.5
Ammon, S.M.6
Gutierrez, H.A.7
Eckel, R.H.8
-
42
-
-
0030021071
-
Decreased brown fat markedly enhances susceptibility to diet-induced obesity, diabetes and hyperlipidemia
-
Hamann, A.J., S. Flier, and B.B. Lowell. 1996. Decreased brown fat markedly enhances susceptibility to diet-induced obesity, diabetes and hyperlipidemia. Endocrinology. 137:21-29.
-
(1996)
Endocrinology
, vol.137
, pp. 21-29
-
-
Hamann, A.J.1
Flier, S.2
Lowell, B.B.3
-
43
-
-
0026503690
-
Effect of increased production of growth hormone on body composition in mice: Transgenic versus control
-
Searle, T.W., J.D. Murray, and P.J. Baker. 1992. Effect of increased production of growth hormone on body composition in mice: transgenic versus control. J. Endocrinology. 132:285-291.
-
(1992)
J. Endocrinology
, vol.132
, pp. 285-291
-
-
Searle, T.W.1
Murray, J.D.2
Baker, P.J.3
-
44
-
-
0028838836
-
Targeted disruption of the β 3-adrenergic receptor gene
-
Susulic, V.S. R.C. Frederich, J. Lawitts, E. Tozzo, B.B. Kahn, M.E. Harper, J. Himms-Hagen, J.S. Flier, and B.B. Lowell. 1995. Targeted disruption of the β 3-adrenergic receptor gene. J. Biol. Chem. 270:29483-29492.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29483-29492
-
-
Susulic, V.S.1
Frederich, R.C.2
Lawitts, J.3
Tozzo, E.4
Kahn, B.B.5
Harper, M.E.6
Himms-Hagen, J.7
Flier, J.S.8
Lowell, B.B.9
-
45
-
-
0029804743
-
Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
-
Erickson, J.C., G. Hollopeter, and R.D. Palmiter. 1996. Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science. 274: 1704-1707.
-
(1996)
Science
, vol.274
, pp. 1704-1707
-
-
Erickson, J.C.1
Hollopeter, G.2
Palmiter, R.D.3
-
46
-
-
0029819643
-
Relationship of plasma leptin to plasma insulin and adiposity in normal weight and overweight women: Effects of dietary fat content and sustained weight loss
-
Havel, P.J., S. Kasim-Karakas, W. Mueller, P.R. Johnson, R.L. Gingerich, and J.S. Stern. 1996. Relationship of plasma leptin to plasma insulin and adiposity in normal weight and overweight women: effects of dietary fat content and sustained weight loss. J. Clin. Endocrinol. Metab. 81:4406-4413.
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 4406-4413
-
-
Havel, P.J.1
Kasim-Karakas, S.2
Mueller, W.3
Johnson, P.R.4
Gingerich, R.L.5
Stern, J.S.6
-
47
-
-
0028793697
-
Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
-
Frederich, R.C., A. Hamann, S. Anderson, B. Lollmann, B.B. Lowell, and J.S. Flier. 1995. Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat. Med. 1:1311-1314.
-
(1995)
Nat. Med.
, vol.1
, pp. 1311-1314
-
-
Frederich, R.C.1
Hamann, A.2
Anderson, S.3
Lollmann, B.4
Lowell, B.B.5
Flier, J.S.6
-
48
-
-
0030966660
-
Relationship between circulating leptin and peripheral fat distribution in obese subjects
-
Lonnqvist, F., A. Wennlund, and P. Arner. 1997. Relationship between circulating leptin and peripheral fat distribution in obese subjects. Int. J. Obes. Relat. Metab. Disord. 21:255-260.
-
(1997)
Int. J. Obes. Relat. Metab. Disord.
, vol.21
, pp. 255-260
-
-
Lonnqvist, F.1
Wennlund, A.2
Arner, P.3
-
49
-
-
0031454125
-
Tumor necrosis factor-α contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes
-
Kirchgessner, T.G., K.T. Uysal, S.M. Wiesbrock, M.W. Marino, and G.S. Hotamisligil. 1997. Tumor necrosis factor-α contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes. J. Clin. Invest. 100:2777-2782.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2777-2782
-
-
Kirchgessner, T.G.1
Uysal, K.T.2
Wiesbrock, S.M.3
Marino, M.W.4
Hotamisligil, G.S.5
-
50
-
-
0031954415
-
Physiological insulinemia acutely modulates plasma leptin
-
Saad, M.F., A. Khan, A. Sharma, R. Michael, M.G. Riad-Gabriel, R. Boyadjian, S.D. Jinagouda, G.M. Steil, and V. Kamdar. 1998. Physiological insulinemia acutely modulates plasma leptin. Diabetes. 47:544-549.
-
(1998)
Diabetes
, vol.47
, pp. 544-549
-
-
Saad, M.F.1
Khan, A.2
Sharma, A.3
Michael, R.4
Riad-Gabriel, M.G.5
Boyadjian, R.6
Jinagouda, S.D.7
Steil, G.M.8
Kamdar, V.9
-
51
-
-
0040381066
-
Leptin impairs metabolic actions of insulin in isolated rat adipocytes
-
Muller, G., J. Ertl, M. Gerl, and G. Preibisch. 1997. Leptin impairs metabolic actions of insulin in isolated rat adipocytes. J. Biol. Chem. 272:10585-10593.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10585-10593
-
-
Muller, G.1
Ertl, J.2
Gerl, M.3
Preibisch, G.4
-
52
-
-
0029860791
-
Modulation of insulin activities by leptin
-
Cohen, B., D. Novick, and M. Rubinstein. 1996. Modulation of insulin activities by leptin. Science. 274:1185-1188.
-
(1996)
Science
, vol.274
, pp. 1185-1188
-
-
Cohen, B.1
Novick, D.2
Rubinstein, M.3
-
53
-
-
0030955188
-
Leptin constrains acetylcholine-induced insulin secretion from pancreatic islets of ob/ob mice
-
Chen, N.G., A.G. Swick, and D.R. Romsos. 1997. Leptin constrains acetylcholine-induced insulin secretion from pancreatic islets of ob/ob mice. J. Clin. Invest. 100:1174-1179.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 1174-1179
-
-
Chen, N.G.1
Swick, A.G.2
Romsos, D.R.3
-
54
-
-
0030965884
-
Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
-
Emilsson, V., Y.-L. Liu, M.A. Cawthorne, N.M. Morton, and M. Davenport. 1997. Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes. 46:313-316.
-
(1997)
Diabetes
, vol.46
, pp. 313-316
-
-
Emilsson, V.1
Liu, Y.-L.2
Cawthorne, M.A.3
Morton, N.M.4
Davenport, M.5
-
55
-
-
0029739826
-
Leptin activation of stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
-
Vaisse, C., J.L. Halaas, C.M. Horvath, J.E. Darnell, Jr., M. Stoffel, and J.M. Friedman. 1996. Leptin activation of stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat. Genet. 14:95-97.
-
(1996)
Nat. Genet.
, vol.14
, pp. 95-97
-
-
Vaisse, C.1
Halaas, J.L.2
Horvath, C.M.3
Darnell Jr., J.E.4
Stoffel, M.5
Friedman, J.M.6
-
56
-
-
13344280346
-
Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice
-
Schwartz, M.W., D.G. Baskin, T.R. Bukowski, J.L. Kuijper, D. Foster, G. Lasser, D.E. Prunkard, D. Porte, Jr., S.C. Woods, R.J. Seeley, and D.S. Weigle. 1996. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes. 45:531-535.
-
(1996)
Diabetes
, vol.45
, pp. 531-535
-
-
Schwartz, M.W.1
Baskin, D.G.2
Bukowski, T.R.3
Kuijper, J.L.4
Foster, D.5
Lasser, G.6
Prunkard, D.E.7
Porte Jr., D.8
Woods, S.C.9
Seeley, R.J.10
Weigle, D.S.11
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