-
1
-
-
60249086665
-
Deaths: Preliminary data for 2008
-
Mininno, A. M., and Xu., J. Q., and Kochanek, K. D. (2010) Deaths: preliminary data for 2008. National Vital Statistics Reports 59, 1-52
-
(2010)
National Vital Statistics Reports
, vol.59
, pp. 1-52
-
-
Mininno, A.M.1
Xu, J.Q.2
Kochanek, K.D.3
-
2
-
-
21044458874
-
Decreased histone deacetylase activity in chronic obstructive pulmonary disease
-
Ito, K., Ito, M., Elliott, W. M., Cosio, B., Caramori, G., and Kon., O. M., Barczyk, A., Hayashi, S., Adcock, I. M., Hogg, J. C, and Barnes, P. J. (2005) Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N. Engl. J. Med. 352, 1967-1976
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 1967-1976
-
-
Ito, K.1
Ito, M.2
Elliott, W.M.3
Cosio, B.4
Caramori, G.5
Kon, O.M.6
Barczyk, A.7
Hayashi, S.8
Adcock, I.M.9
Hogg, J.C.10
Barnes, P.J.11
-
3
-
-
33745855449
-
Remodeling in asthma and chronic obstructive pulmonary disease
-
Postma, D. S., and Timens, W. (2006) Remodeling in asthma and chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 3, 434-439
-
(2006)
Proc. Am. Thorac. Soc.
, vol.3
, pp. 434-439
-
-
Postma, D.S.1
Timens, W.2
-
4
-
-
36048937539
-
Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients
-
Araya, J., Cambier, S., Markovics, J. A., Wolters, P., Jablons, D., Hill, A., Finkbeiner, W., Jones, K., Broaddus, V. C, Sheppard, D., Barzcak, A., Xiao, Y., Erle, D. J., and Nishimura, S. L. (2007) Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients. J. Clin. Invest. 117, 3551-3562
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 3551-3562
-
-
Araya, J.1
Cambier, S.2
Markovics, J.A.3
Wolters, P.4
Jablons, D.5
Hill, A.6
Finkbeiner, W.7
Jones, K.8
Broaddus, V.C.9
Sheppard, D.10
Barzcak, A.11
Xiao, Y.12
Erle, D.J.13
Nishimura, S.L.14
-
5
-
-
33646565675
-
Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations
-
Papi, A., and Bellettato., C. M., Braccioni, F., Romagnoli, M., Casolari, P., Caramori, G., Fabbri, L. M., and Johnston, S. L. (2006) Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations. Am. J. Respir. Crit. Care Med. 173, 1114-1121
-
(2006)
Am. J. Respir. Crit. Care Med.
, vol.173
, pp. 1114-1121
-
-
Papi, A.1
Bellettato, C.M.2
Braccioni, F.3
Romagnoli, M.4
Casolari, P.5
Caramori, G.6
Fabbri, L.M.7
Johnston, S.L.8
-
6
-
-
79959993129
-
Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β
-
Kitamura, H., Cambier, S., Somanath, S., Barker, T., Minagawa, S., Markovics, J., Goodsell, A., Publicover, J., Reichardt, L., Jablons, D., Wolters, P., Hill, A., Marks, J. D., Lou, J., Pittet, J. F., Gauldie, J., Baron, J. L., and Nishimura, S. L. (2011) Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β. J. Clin. Invest. 121, 2863-2875
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2863-2875
-
-
Kitamura, H.1
Cambier, S.2
Somanath, S.3
Barker, T.4
Minagawa, S.5
Markovics, J.6
Goodsell, A.7
Publicover, J.8
Reichardt, L.9
Jablons, D.10
Wolters, P.11
Hill, A.12
Marks, J.D.13
Lou, J.14
Pittet, J.F.15
Gauldie, J.16
Baron, J.L.17
Nishimura, S.L.18
-
7
-
-
84903780541
-
Selective targeting of TGF-β activation to treat fibroinflammatory airway disease
-
Minagawa, S., Lou, J., Seed, R. I., Cormier, A., Wu, S., Cheng, Y., Murray, L., Tsui, P., Connor, J., Herbst, R., Govaerts, C, Barker, T., Cambier, S., Yanagisawa, H., Goodsell, A., Hashimoto, M., Brand, O. J., Cheng, R., Ma, R., McKnelly, K. J., Wen, W., Hill, A., Jablons, D., Wolters, P., Kitamura, H, Araya, J., Barczak, A. J., Erle, D. J., Reichardt, L. F., Marks, J. D., Baron, J. L., and Nishimura, S. L. (2014) Selective targeting of TGF-β activation to treat fibroinflammatory airway disease. Sci. Transl. Med. 6, 241ra79
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Minagawa, S.1
Lou, J.2
Seed, R.I.3
Cormier, A.4
Wu, S.5
Cheng, Y.6
Murray, L.7
Tsui, P.8
Connor, J.9
Herbst, R.10
Govaerts, C.11
Barker, T.12
Cambier, S.13
Yanagisawa, H.14
Goodsell, A.15
Hashimoto, M.16
Brand, O.J.17
Cheng, R.18
Ma, R.19
McKnelly, K.J.20
Wen, W.21
Hill, A.22
Jablons, D.23
Wolters, P.24
Kitamura, H.25
Araya, J.26
Barczak, A.J.27
Erle, D.J.28
Reichardt, L.F.29
Marks, J.D.30
Baron, J.L.31
Nishimura, S.L.32
more..
-
8
-
-
79952218099
-
P2X7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema
-
Lucattelli, M., Cicko, S., Müller, T., Lommatzsch, M., De Cunto, G., Cardini, S., Sundas, W., Grimm, M., Zeiser, R., Dürk, T., Zissel, G., Sorichter, S., Ferrari, D., Di Virgilio, F., Virchow, J. C, Lungarella, G., and Idzko, M. (2011) P2X7 receptor signaling in the pathogenesis of smoke-induced lung inflammation and emphysema. Am. J. Respir. Cell Mol. Biol. 44, 423-429
-
(2011)
Am. J. Respir. Cell Mol. Biol.
, vol.44
, pp. 423-429
-
-
Lucattelli, M.1
Cicko, S.2
Müller, T.3
Lommatzsch, M.4
De Cunto, G.5
Cardini, S.6
Sundas, W.7
Grimm, M.8
Zeiser, R.9
Dürk, T.10
Zissel, G.11
Sorichter, S.12
Ferrari, D.13
Di Virgilio, F.14
Virchow, J.C.15
Lungarella, G.16
Idzko, M.17
-
9
-
-
80051925145
-
TLR4protein contributes to cigarette smoke-induced matrix metalloproteinase-1 (MMP-1) expression in chronic obstructive pulmonary disease
-
Geraghty, P., and Dabo., A. J., and D'Armiento, J. (2011) TLR4protein contributes to cigarette smoke-induced matrix metalloproteinase-1 (MMP-1) expression in chronic obstructive pulmonary disease. J. Biol. Chem. 286, 30211-30218
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 30211-30218
-
-
Geraghty, P.1
Dabo, A.J.2
D'Armiento, J.3
-
10
-
-
48749097634
-
Cigarette smoke selectively enhances viral PAMP-and virus-induced pulmonary innate immune and remodeling responses in mice
-
Kang, M. J., and Lee., C. G., Lee, J. Y., Dela Cruz, C. S., Chen, Z. J., Enelow, R., and Elias, J. A. (2008) Cigarette smoke selectively enhances viral PAMP-and virus-induced pulmonary innate immune and remodeling responses in mice. J. Clin. Invest. 118, 2771-2784
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2771-2784
-
-
Kang, M.J.1
Lee, C.G.2
Lee, J.Y.3
Dela Cruz, C.S.4
Chen, Z.J.5
Enelow, R.6
Elias, J.A.7
-
11
-
-
77956993930
-
Association of severity of COPD with IgE and interleukin-1β: Monaldi archives for chest disease
-
Singh, B., Arora, S., and Khanna, V. (2010) Association of severity of COPD with IgE and interleukin-1β: Monaldi archives for chest disease. Secondo Ateneo 73, 86-87
-
(2010)
Secondo Ateneo
, vol.73
, pp. 86-87
-
-
Singh, B.1
Arora, S.2
Khanna, V.3
-
12
-
-
24344493434
-
Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease
-
Gessner, C, Scheibe, R., Wötzel, M., Hammerschmidt, S., Kuhn, H., Engelmann, L., Hoheisel, G., Gillissen, A., Sack, U., and Wirtz, H. (2005) Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease. Respir. Med. 99, 1229-1240
-
(2005)
Respir. Med.
, vol.99
, pp. 1229-1240
-
-
Gessner, C.1
Scheibe, R.2
Wötzel, M.3
Hammerschmidt, S.4
Kuhn, H.5
Engelmann, L.6
Hoheisel, G.7
Gillissen, A.8
Sack, U.9
Wirtz, H.10
-
13
-
-
79960767641
-
Role of IL-1α and the nlrp3/caspase-1/ IL-1β axis in cigarette smoke-induced pulmonary inflammation and COPD
-
Pauwels, N. S., and Bracke., K. R., Dupont, L. L., Van Pottelberge, G. R., Provoost, S., Vanden Berghe, T., Vandenabeele, P., Lambrecht, B. N, Joos, G. F., and Brusselle, G. G. (2011) Role of IL-1α and the Nlrp3/caspase-1/ IL-1β axis in cigarette smoke-induced pulmonary inflammation and COPD. Eur. Respir. J. 38, 1019-1028
-
(2011)
Eur. Respir. J.
, vol.38
, pp. 1019-1028
-
-
Pauwels, N.S.1
Bracke, K.R.2
Dupont, L.L.3
Van Pottelberge, G.R.4
Provoost, S.5
Vanden Berghe, T.6
Vandenabeele, P.7
Lambrecht, B.N.8
Joos, G.F.9
Brusselle, G.G.10
-
14
-
-
67651244671
-
Imbalances between interleukin-1 and tumor necrosis factor agonists and antagonists in stable COPD
-
Sapey, E., Ahmad, A., Bayley, D., Newbold, P., Snell, N, Rugman, P., and Stockley, R. A. (2009) Imbalances between interleukin-1 and tumor necrosis factor agonists and antagonists in stable COPD. J. Clin. Immunol. 29, 508-516
-
(2009)
J. Clin. Immunol.
, vol.29
, pp. 508-516
-
-
Sapey, E.1
Ahmad, A.2
Bayley, D.3
Newbold, P.4
Snell, N.5
Rugman, P.6
Stockley, R.A.7
-
15
-
-
16444377075
-
Interleukin-1β causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung
-
Lappalainen, U., and Whitsett., J. A., Wert, S. E., Tichelaar, J. W., and Bry, K. (2005) Interleukin-1β causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung. Am. J. Respir. Cell Mol. Biol. 32, 311-318
-
(2005)
Am. J. Respir. Cell Mol. Biol.
, vol.32
, pp. 311-318
-
-
Lappalainen, U.1
Whitsett, J.A.2
Wert, S.E.3
Tichelaar, J.W.4
Bry, K.5
-
16
-
-
63349099346
-
The role of interleukin-1β in murine cigarette smoke-induced emphysema and small airway remodeling
-
Churg, A., Zhou, S., Wang, X., Wang, R., and Wright, J. L. (2009) The role of interleukin-1β in murine cigarette smoke-induced emphysema and small airway remodeling. Am. J. Respir. Cell Mol. Biol. 40, 482-490
-
(2009)
Am. J. Respir. Cell Mol. Biol.
, vol.40
, pp. 482-490
-
-
Churg, A.1
Zhou, S.2
Wang, X.3
Wang, R.4
Wright, J.L.5
-
17
-
-
40449118020
-
Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent
-
Doz, E., Noulin, N., Boichot, E., Guénon, I., Fick, L., Le Bert, M., Lagente, V., Ryffel, B., Schnyder, B., Quesniaux, V. F., and Couillin, I. (2008) Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent. J. Immunol. 180, 1169-1178
-
(2008)
J. Immunol.
, vol.180
, pp. 1169-1178
-
-
Doz, E.1
Noulin, N.2
Boichot, E.3
Guénon, I.4
Fick, L.5
Le Bert, M.6
Lagente, V.7
Ryffel, B.8
Schnyder, B.9
Quesniaux, V.F.10
Couillin, I.11
-
18
-
-
0034967219
-
Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis
-
Kolb, M., and Margetts., P. J., Anthony, D. C, Pitossi, F., and Gauldie, J. (2001) Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis. J. Clin. Invest. 107, 1529-1536
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 1529-1536
-
-
Kolb, M.1
Margetts, P.J.2
Anthony, D.C.3
Pitossi, F.4
Gauldie, J.5
-
19
-
-
84855441194
-
Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in mice
-
Podowski, M., Calvi, C, Metzger, S., Misono, K., Poonyagariyagorn, H., Lopez-Mercado, A., Ku, T., Lauer, T., McGrath-Morrow, S., Berger, A., Cheadle, C, Tuder, R., Dietz, H. C, Mitzner, W., Wise, R., and Neptune, E. (2012) Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in mice. J. Clin. Invest. 122, 229-240
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 229-240
-
-
Podowski, M.1
Calvi, C.2
Metzger, S.3
Misono, K.4
Poonyagariyagorn, H.5
Lopez-Mercado, A.6
Ku, T.7
Lauer, T.8
McGrath-Morrow, S.9
Berger, A.10
Cheadle, C.11
Tuder, R.12
Dietz, H.C.13
Mitzner, W.14
Wise, R.15
Neptune, E.16
-
20
-
-
17044453955
-
Increased expression of transforming growth factor-β1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (COPD)
-
Takizawa, H, Tanaka, M., Takami, K., Ohtoshi, T., Ito, K., Satoh, M., Okada, Y., Yamasawa, F., Nakahara, K., and Umeda, A. (2001) Increased expression of transforming growth factor-β1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (COPD). Am. J. Respir. Crit. Care Med. 163, 1476-1483
-
(2001)
Am. J. Respir. Crit. Care Med.
, vol.163
, pp. 1476-1483
-
-
Takizawa, H.1
Tanaka, M.2
Takami, K.3
Ohtoshi, T.4
Ito, K.5
Satoh, M.6
Okada, Y.7
Yamasawa, F.8
Nakahara, K.9
Umeda, A.10
-
21
-
-
79959250326
-
Latent TGF-β structure and activation
-
Shi, M., Zhu, J., Wang, R., Chen, X., Mi, L., Walz, T., and Springer, T. A. (2011) Latent TGF-β structure and activation. Nature 474, 343-349
-
(2011)
Nature
, vol.474
, pp. 343-349
-
-
Shi, M.1
Zhu, J.2
Wang, R.3
Chen, X.4
Mi, L.5
Walz, T.6
Springer, T.A.7
-
22
-
-
0037192933
-
The integrin α(v)β8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-β1
-
Mu, D., Cambier, S., Fjellbirkeland, L., Baron, J. L., Munger, J. S., Kawakatsu, H, Sheppard, D., Broaddus, V. C, and Nishimura, S. L. (2002) The integrin α(v)β8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-β1. J. Cell Biol. 157, 493-507
-
(2002)
J. Cell Biol.
, vol.157
, pp. 493-507
-
-
Mu, D.1
Cambier, S.2
Fjellbirkeland, L.3
Baron, J.L.4
Munger, J.S.5
Kawakatsu, H.6
Sheppard, D.7
Broaddus, V.C.8
Nishimura, S.L.9
-
23
-
-
0031670654
-
Interactions between growth factors and integrins: Latent forms of transforming growth factor-β are ligands for the integrin αvβ1
-
Munger, J. S., and Harpel., J. G., Giancotti, F. G., and Rifkin, D. B. (1998) Interactions between growth factors and integrins: latent forms of transforming growth factor-β are ligands for the integrin αvβ1. Mol. Biol. Cell 9, 2627-2638
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 2627-2638
-
-
Munger, J.S.1
Harpel, J.G.2
Giancotti, F.G.3
Rifkin, D.B.4
-
24
-
-
37249044357
-
Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix
-
Wipff, P. J., and Rifkin., D. B., Meister, J. J., and Hinz, B. (2007) Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix. J. Cell Biol. 179, 1311-1323
-
(2007)
J. Cell Biol.
, vol.179
, pp. 1311-1323
-
-
Wipff, P.J.1
Rifkin, D.B.2
Meister, J.J.3
Hinz, B.4
-
25
-
-
0033524949
-
The integrin αvβ6 binds and activates latent TGF β1: A mechanism for regulating pulmonary inflammation and fibrosis
-
Munger, J. S., Huang, X., Kawakatsu, H., Griffiths, M. J., Dalton, S. L., Wu, J., Pittet, J. F., Kaminski, N, Garat, C, and Matthay., M. A., Rifkin, D. B., and Sheppard, D. (1999) The integrin αvβ6 binds and activates latent TGF β1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell 96, 319-328
-
(1999)
Cell
, vol.96
, pp. 319-328
-
-
Munger, J.S.1
Huang, X.2
Kawakatsu, H.3
Griffiths, M.J.4
Dalton, S.L.5
Wu, J.6
Pittet, J.F.7
Kaminski, N.8
Garat, C.9
Matthay, M.A.10
Rifkin, D.B.11
Sheppard, D.12
-
26
-
-
61949349656
-
Mice that lack activity of αvβ6-and αvβ8-integrins reproduce the Abnormalities of tgfb1- and tgfb3-null mice
-
Aluwihare, P., Mu, Z., Zhao, Z., Yu, D., and Weinreb., P. H., Horan, G. S., Violette, S. M., and Munger, J. S. (2009) Mice that lack activity of αvβ6-and αvβ8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice. J. Cell Sci. 122, 227-232
-
(2009)
J. Cell Sci.
, vol.122
, pp. 227-232
-
-
Aluwihare, P.1
Mu, Z.2
Zhao, Z.3
Yu, D.4
Weinreb, P.H.5
Horan, G.S.6
Violette, S.M.7
Munger, J.S.8
-
27
-
-
84862776751
-
IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction
-
Kudo, M., and Melton., A. C., Chen, C., Engler, M. B., Huang, K. E., Ren, X., Wang, Y., Bernstein, X., Li, J. T., Atabai, K., Huang, X., and Sheppard, D. (2012) IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction. Nat Med. 18, 547-554
-
(2012)
Nat Med.
, vol.18
, pp. 547-554
-
-
Kudo, M.1
Melton, A.C.2
Chen, C.3
Engler, M.B.4
Huang, K.E.5
Ren, X.6
Wang, Y.7
Bernstein, X.8
Li, J.T.9
Atabai, K.10
Huang, X.11
Sheppard, D.12
-
28
-
-
78649807601
-
Expression of αvβ8 integrin on dendritic cells regulates th17 cell development and experimental autoimmune encephalomyelitis in mice
-
Melton, A. C., Bailey-Bucktrout, S. L., Travis, M. A., Fife, B. T., Bluestone, J. A., and Sheppard, D. (2010) Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice. J. Clin. Invest. 120, 4436-4444
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 4436-4444
-
-
Melton, A.C.1
Bailey-Bucktrout, S.L.2
Travis, M.A.3
Fife, B.T.4
Bluestone, J.A.5
Sheppard, D.6
-
29
-
-
34548208943
-
Loss of integrin α(v)β8 on dendritic cells causes autoimmunity and colitis in mice
-
Travis, M. A., Reizis, B., Melton, A. C., Masteller, E., Tang, Q., and Proctor., J. M., Wang, Y., Bernstein, X., Huang, X., and Reichardt., L. F., Bluestone, J. A., and Sheppard, D. (2007) Loss of integrin α(v)β8 on dendritic cells causes autoimmunity and colitis in mice. Nature 449, 361-365
-
(2007)
Nature
, vol.449
, pp. 361-365
-
-
Travis, M.A.1
Reizis, B.2
Melton, A.C.3
Masteller, E.4
Tang, Q.5
Proctor, J.M.6
Wang, Y.7
Bernstein, X.8
Huang, X.9
Reichardt, L.F.10
Bluestone, J.A.11
Sheppard, D.12
-
30
-
-
80054696391
-
Interleukin-1β induces increased transcriptional activation of the transforming growth factor-β-activating integrin subunit β8 through altering chromatin architecture
-
Markovics, J. A., Araya, J., Cambier, S., Somanath, S., Gline, S., Jablons, D., Hill, A., and Wolters., P. J., and Nishimura, S. L. (2011) Interleukin-1β induces increased transcriptional activation of the transforming growth factor-β-activating integrin subunit β8 through altering chromatin architecture. J. Biol. Chem. 286, 36864-36874
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 36864-36874
-
-
Markovics, J.A.1
Araya, J.2
Cambier, S.3
Somanath, S.4
Gline, S.5
Jablons, D.6
Hill, A.7
Wolters, P.J.8
Nishimura, S.L.9
-
31
-
-
24944464002
-
Remodeling and inflammation of bronchi in asthma and chronic obstructive pulmonary disease
-
Jeffery, P. K. (2004) Remodeling and inflammation of bronchi in asthma and chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 1, 176-183
-
(2004)
Proc. Am. Thorac. Soc.
, vol.1
, pp. 176-183
-
-
Jeffery, P.K.1
-
32
-
-
33746602210
-
Integrin-mediated transforming growth factor-β activation regulates homeostasis of the pulmonary epithelial-mesenchymal trophic unit
-
Araya, J., Cambier, S., Morris, A., Finkbeiner, W., and Nishimura, S. L. (2006) Integrin-mediated transforming growth factor-β activation regulates homeostasis of the pulmonary epithelial-mesenchymal trophic unit. Am. J. Pathol. 169, 405-415
-
(2006)
Am. J. Pathol.
, vol.169
, pp. 405-415
-
-
Araya, J.1
Cambier, S.2
Morris, A.3
Finkbeiner, W.4
Nishimura, S.L.5
-
33
-
-
34248371233
-
Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease
-
Demedts, I. K., and Bracke., K. R., Van Pottelberge, G., Testelmans, D., Verleden, G. M., Vermassen, F. E., Joos, G. F., and Brusselle, G. G. (2007) Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 175, 998-1005
-
(2007)
Am. J. Respir. Crit. Care Med.
, vol.175
, pp. 998-1005
-
-
Demedts, I.K.1
Bracke, K.R.2
Van Pottelberge, G.3
Testelmans, D.4
Verleden, G.M.5
Vermassen, F.E.6
Joos, G.F.7
Brusselle, G.G.8
-
34
-
-
70049101757
-
Biology of lung dendritic cells at the origin of asthma
-
Lambrecht, B. N, and Hammad, H. (2009) Biology of lung dendritic cells at the origin of asthma. Immunity 31, 412-424
-
(2009)
Immunity
, vol.31
, pp. 412-424
-
-
Lambrecht, B.N.1
Hammad, H.2
-
35
-
-
79955523521
-
Innate immune response to influenza virus
-
Wu, S., and Metcalf., J. P., and Wu, W. (2011) Innate immune response to influenza virus. Curr. Opin. Infect. Dis. 24, 235-240
-
(2011)
Curr. Opin. Infect. Dis.
, vol.24
, pp. 235-240
-
-
Wu, S.1
Metcalf, J.P.2
Wu, W.3
-
36
-
-
3242726202
-
Lymphotoxin β receptor signaling induces the chemokine CCL20 in intestinal epithelium
-
Rumbo, M., Sierro, F., Debard, N., Kraehenbuhl, J. P., and Finke, D. (2004) Lymphotoxin β receptor signaling induces the chemokine CCL20 in intestinal epithelium. Gastroenterology 127, 213-223
-
(2004)
Gastroenterology
, vol.127
, pp. 213-223
-
-
Rumbo, M.1
Sierro, F.2
Debard, N.3
Kraehenbuhl, J.P.4
Finke, D.5
-
37
-
-
2542609844
-
Smad3 as a mediator of the fibrotic response
-
Flanders, K. C. (2004) Smad3 as a mediator of the fibrotic response. Int. J. Exp. Pathol. 85, 47-64
-
(2004)
Int. J. Exp. Pathol.
, vol.85
, pp. 47-64
-
-
Flanders, K.C.1
-
38
-
-
0038798012
-
Airway epithelial cells release MIP-3α/CCL20 in response to cytokines and ambient particulate matter
-
Reibman, J., Hsu, Y., Chen, L. C, Bleck, B., and Gordon, T. (2003) Airway epithelial cells release MIP-3α/CCL20 in response to cytokines and ambient particulate matter. Am. J. Respir. Cell Mol. Biol. 28, 648-654
-
(2003)
Am. J. Respir. Cell Mol. Biol.
, vol.28
, pp. 648-654
-
-
Reibman, J.1
Hsu, Y.2
Chen, L.C.3
Bleck, B.4
Gordon, T.5
-
39
-
-
0030984446
-
CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3α and is highly expressed in human dendritic cells
-
Greaves, D. R., Wang, W., Dairaghi, D. J., Dieu, M. C, Saint-Vis, B., Franz-Bacon, K., Rossi, D., Caux, C, McClanahan, T., Gordon, S., Zlotnik, A., and Schall, T. J. (1997) CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3α and is highly expressed in human dendritic cells. J. Exp. Med. 186, 837-844
-
(1997)
J. Exp. Med.
, vol.186
, pp. 837-844
-
-
Greaves, D.R.1
Wang, W.2
Dairaghi, D.J.3
Dieu, M.C.4
Saint-Vis, B.5
Franz-Bacon, K.6
Rossi, D.7
Caux, C.8
McClanahan, T.9
Gordon, S.10
Zlotnik, A.11
Schall, T.J.12
-
40
-
-
84927662532
-
A critical role for dendritic cells in the evolution of IL-1β-mediated murine airway disease
-
Hashimoto, M., Yanagisawa, H., Minagawa, S., Sen, D., Goodsell, A., Ma, R., Moermans, C, and McKnelly., K. J., Baron, J. L., Krummel, M. F., and Nishimura, S. L. (2015) A critical role for dendritic cells in the evolution of IL-1β-mediated murine airway disease. J. Immunol. 194, 3962-3969
-
(2015)
J. Immunol.
, vol.194
, pp. 3962-3969
-
-
Hashimoto, M.1
Yanagisawa, H.2
Minagawa, S.3
Sen, D.4
Goodsell, A.5
Ma, R.6
Moermans, C.7
McKnelly, K.J.8
Baron, J.L.9
Krummel, M.F.10
Nishimura, S.L.11
-
41
-
-
1542289674
-
Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury
-
Saika, S., Kono-Saika, S., Ohnishi, Y., Sato, M., Muragaki, Y., Ooshima, A., Flanders, K. C, Yoo, J., Anzano, M., Liu, C. Y., Kao, W. W., and Roberts, A. B. (2004) Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury. Am. J. Pathol. 164, 651-663
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 651-663
-
-
Saika, S.1
Kono-Saika, S.2
Ohnishi, Y.3
Sato, M.4
Muragaki, Y.5
Ooshima, A.6
Flanders, K.C.7
Yoo, J.8
Anzano, M.9
Liu, C.Y.10
Kao, W.W.11
Roberts, A.B.12
-
42
-
-
0142104985
-
Smad-dependent and smad-independent pathways in TGF-β family signalling
-
Derynck, R., and Zhang, Y. E. (2003) Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature 425, 577-584
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
43
-
-
0034695483
-
Targeted disruption in murine cells reveals variable requirement for smad4 in transforming growth factor β-related signaling
-
Sirard, C, Kim, S., Mirtsos, C, Tadich, P., and Hoodless., P. A., Itié, A., Maxson, R., and Wrana., J. L., and Mak, T. W. (2000) Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor β-related signaling. J. Biol. Chem. 275, 2063-2070
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2063-2070
-
-
Sirard, C.1
Kim, S.2
Mirtsos, C.3
Tadich, P.4
Hoodless, P.A.5
Itié, A.6
Maxson, R.7
Wrana, J.L.8
Mak, T.W.9
-
44
-
-
84858176226
-
ALK1 signaling inhibits angiogenesis by cooperating with the notch pathway
-
Larrivée, B., Prahst, C, Gordon, E., del Toro, R., Mathivet, T., Duarte, A., Simons, M., and Eichmann, A. (2012) ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway. Dev. Cell 22, 489-500
-
(2012)
Dev. Cell
, vol.22
, pp. 489-500
-
-
Larrivée, B.1
Prahst, C.2
Gordon, E.3
Del Toro, R.4
Mathivet, T.5
Duarte, A.6
Simons, M.7
Eichmann, A.8
-
45
-
-
84895983200
-
ALK1 heterozygosity increases extracellular matrix protein expression, proliferation and migration in fibroblasts
-
Muñoz-Félix, J. M., Perretta-Tejedor, N., Eleno, N., López-Novoa, J. M., and Martínez-Salgado, C. (2014) ALK1 heterozygosity increases extracellular matrix protein expression, proliferation and migration in fibroblasts. Biochim. Biophys. Acta 1843, 1111-1122
-
(2014)
Biochim. Biophys. Acta
, vol.1843
, pp. 1111-1122
-
-
Muñoz-Félix, J.M.1
Perretta-Tejedor, N.2
Eleno, N.3
López-Novoa, J.M.4
Martínez-Salgado, C.5
-
46
-
-
84891955366
-
Direct observation of a transient ternary complex during IκBα-mediated dissociation of NF-ΚB from DNA
-
Alverdi, V., Hetrick, B., Joseph, S., and Komives, E. A. (2014) Direct observation of a transient ternary complex during IκBα-mediated dissociation of NF-ΚB from DNA. Proc. Natl. Acad. Sci. U.S.A. 111, 225-230
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 225-230
-
-
Alverdi, V.1
Hetrick, B.2
Joseph, S.3
Komives, E.A.4
-
47
-
-
33644530060
-
A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-κB-dependent gene activity
-
Bosisio, D., Marazzi, I., Agresti, A., Shimizu, N, and Bianchi., M. E., and Natoli, G. (2006) A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-κB-dependent gene activity. EMBOJ. 25, 798-810
-
(2006)
EMBOJ
, vol.25
, pp. 798-810
-
-
Bosisio, D.1
Marazzi, I.2
Agresti, A.3
Shimizu, N.4
Bianchi, M.E.5
Natoli, G.6
-
48
-
-
82755186757
-
Regulation of IFN-A1 promoter activity (IFN-A1/IL-29) in human airway epithelial cells
-
Siegel, R., Eskdale, J., and Gallagher, G. (2011) Regulation of IFN-A1 promoter activity (IFN-A1/IL-29) in human airway epithelial cells. J. Immunol. 187, 5636-5644
-
(2011)
J. Immunol.
, vol.187
, pp. 5636-5644
-
-
Siegel, R.1
Eskdale, J.2
Gallagher, G.3
-
49
-
-
48449086316
-
TGF-β: A master of all T cell trades
-
Li, M. O., and Flavell, R. A. (2008) TGF-β: a master of all T cell trades. Cell 134, 392-404
-
(2008)
Cell
, vol.134
, pp. 392-404
-
-
Li, M.O.1
Flavell, R.A.2
-
50
-
-
67049164997
-
Homeostatic role of transforming growth factor-β in the oral cavity and esophagus of mice and its expression by mast cells in these tissues
-
Vitsky, A., Waire, J., Pawliuk, R., Bond, A., Matthews, D., Lacasse, E., Hawes, M. L., Nelson, C, Richards, S., and Piepenhagen., P. A., Garman, R. D., Andrews, L., Thurberg, B. L., Lonning, S., Ledbetter, S., and Ruzek, M. C. (2009) Homeostatic role of transforming growth factor-β in the oral cavity and esophagus of mice and its expression by mast cells in these tissues. Am. J. Pathol. 174, 2137-2149
-
(2009)
Am. J. Pathol.
, vol.174
, pp. 2137-2149
-
-
Vitsky, A.1
Waire, J.2
Pawliuk, R.3
Bond, A.4
Matthews, D.5
Lacasse, E.6
Hawes, M.L.7
Nelson, C.8
Richards, S.9
Piepenhagen, P.A.10
Garman, R.D.11
Andrews, L.12
Thurberg, B.L.13
Lonning, S.14
Ledbetter, S.15
Ruzek, M.C.16
-
51
-
-
84899732254
-
Cytokine inhibition in the treatment of COPD
-
Caramori, G., and Adcock., I. M., Di Stefano, A., and Chung, K. F. (2014) Cytokine inhibition in the treatment of COPD. Int. J. Chron. Obstruct. Pulmon. Dis. 9, 397-412
-
(2014)
Int. J. Chron. Obstruct. Pulmon. Dis.
, vol.9
, pp. 397-412
-
-
Caramori, G.1
Adcock, I.M.2
Di Stefano, A.3
Chung, K.F.4
-
52
-
-
0028814278
-
Balance of IL-1 receptor antagonist/IL-1β in rheumatoid synovium and its regulation by IL-4 and IL-10
-
Chomarat, P., Vannier, E., Dechanet, J., Rissoan, M. C, Banchereau, J., and Dinarello., C. A., and Miossec, P. (1995) Balance of IL-1 receptor antagonist/IL-1β in rheumatoid synovium and its regulation by IL-4 and IL-10. J. Immunol. 154, 1432-1439
-
(1995)
J. Immunol.
, vol.154
, pp. 1432-1439
-
-
Chomarat, P.1
Vannier, E.2
Dechanet, J.3
Rissoan, M.C.4
Banchereau, J.5
Dinarello, C.A.6
Miossec, P.7
-
53
-
-
67149130597
-
Anakinra for rheumatoid arthritis: A systematic review
-
Mertens, M., and Singh, J. A. (2009) Anakinra for rheumatoid arthritis: a systematic review. J. Rheumatol. 36, 1118-1125
-
(2009)
J. Rheumatol.
, vol.36
, pp. 1118-1125
-
-
Mertens, M.1
Singh, J.A.2
-
54
-
-
0032573407
-
Molecular cloning, functional characterization and mRNA expression analysis of the murine chemokine receptor CCR6 and its specific ligand MIP-3α
-
Varona, R., Zaballos, A., Gutiérrez, J., Martín, P., Roncal, F., and Albar., J. P., Ardavín, C, and Márquez, G. (1998) Molecular cloning, functional characterization and mRNA expression analysis of the murine chemokine receptor CCR6 and its specific ligand MIP-3α. FEBSLett. 440, 188-194
-
(1998)
FEBSLett.
, vol.440
, pp. 188-194
-
-
Varona, R.1
Zaballos, A.2
Gutiérrez, J.3
Martín, P.4
Roncal, F.5
Albar, J.P.6
Ardavín, C.7
Márquez, G.8
|