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Volumn 25, Issue 4, 2006, Pages 798-810

A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-κB-dependent gene activity

Author keywords

Enhanceosome; Kinetic microscopy; NF B; Rel; Transcription

Indexed keywords

DIMER; ENHANCEOSOME; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR;

EID: 33644530060     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600977     Document Type: Article
Times cited : (167)

References (44)
  • 1
    • 15944375439 scopus 로고    scopus 로고
    • GR and HMGB1 interact only within chromatin and influence each other's residence time
    • Agresti A, Scaffidi P, Riva A, Caiolfa VR, Bianchi ME (2005) GR and HMGB1 interact only within chromatin and influence each other's residence time. Mol Cell 18: 109-121
    • (2005) Mol Cell , vol.18 , pp. 109-121
    • Agresti, A.1    Scaffidi, P.2    Riva, A.3    Caiolfa, V.R.4    Bianchi, M.E.5
  • 2
    • 0034802887 scopus 로고    scopus 로고
    • The p65 (RelA) subunit of NF-κB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
    • Ashburner BP, Westerheide SD, Baldwin Jr AS (2001) The p65 (RelA) subunit of NF-κB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol 21: 7065-7077
    • (2001) Mol Cell Biol , vol.21 , pp. 7065-7077
    • Ashburner, B.P.1    Westerheide, S.D.2    Baldwin Jr., A.S.3
  • 5
    • 0032498230 scopus 로고    scopus 로고
    • The enhanceosome and transcriptional synergy
    • Carey M (1998) The enhanceosome and transcriptional synergy. Cell 92: 5-8
    • (1998) Cell , vol.92 , pp. 5-8
    • Carey, M.1
  • 6
    • 0037025395 scopus 로고    scopus 로고
    • The kappa B DNA sequence from the HIV long terminal repeat functions as an allosteric regulator of HIV transcription
    • Chen-Park FE, Huang DB, Noro B, Thanos D, Ghosh G (2002) The kappa B DNA sequence from the HIV long terminal repeat functions as an allosteric regulator of HIV transcription. J Biol Chem 277: 24701-24708
    • (2002) J Biol Chem , vol.277 , pp. 24701-24708
    • Chen-Park, F.E.1    Huang, D.B.2    Noro, B.3    Thanos, D.4    Ghosh, G.5
  • 8
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh S, May MJ, Kopp EB (1998) NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 16: 225-260
    • (1998) Annu Rev Immunol , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 9
    • 0028986250 scopus 로고
    • Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA binding and multiple protein-protein interactions
    • Giese K, Kingsley C, Kirshner JR, Grosschedl R (1995) Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA binding and multiple protein-protein interactions. Genes Dev 9: 995-1008
    • (1995) Genes Dev , vol.9 , pp. 995-1008
    • Giese, K.1    Kingsley, C.2    Kirshner, J.R.3    Grosschedl, R.4
  • 10
    • 0028178430 scopus 로고
    • Purification, reconstitution, and IκB association of the c-Rel-p65 (RelA) complex, a strong activator of transcription
    • Hansen SK, Baeuerle PA, Blasi F (1994) Purification, reconstitution, and IκB association of the c-Rel-p65 (RelA) complex, a strong activator of transcription. Mol Cell Biol 14: 2593-2603
    • (1994) Mol Cell Biol , vol.14 , pp. 2593-2603
    • Hansen, S.K.1    Baeuerle, P.A.2    Blasi, F.3
  • 11
    • 0037044575 scopus 로고    scopus 로고
    • The IκB-NF-κB signaling module: Temporal control and selective gene activation
    • Hoffmann A, Levchenko A, Scott ML, Baltimore D (2002) The IκB-NF-κB signaling module: temporal control and selective gene activation. Science 298: 1241-1245
    • (2002) Science , vol.298 , pp. 1241-1245
    • Hoffmann, A.1    Levchenko, A.2    Scott, M.L.3    Baltimore, D.4
  • 12
    • 17844386319 scopus 로고    scopus 로고
    • IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
    • Lawrence T, Bebien M, Liu GY, Nizet V, Karin M (2005) IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation. Nature 434: 1138-1143
    • (2005) Nature , vol.434 , pp. 1138-1143
    • Lawrence, T.1    Bebien, M.2    Liu, G.Y.3    Nizet, V.4    Karin, M.5
  • 15
    • 0343415609 scopus 로고    scopus 로고
    • The glucocorticoid receptor: Rapid exchange with regulatory sites in living cells
    • McNally JG, Muller WG, Walker D, Wolford R, Hager GL (2000) The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. Science 287: 1262-1265
    • (2000) Science , vol.287 , pp. 1262-1265
    • McNally, J.G.1    Muller, W.G.2    Walker, D.3    Wolford, R.4    Hager, G.L.5
  • 17
    • 2642544592 scopus 로고    scopus 로고
    • Estrogen receptor-α directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter
    • Metivier R, Penot G, Hubner MR, Reid G, Brand H, Kos M, Gannon F (2003) Estrogen receptor-α directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell 115: 751-763
    • (2003) Cell , vol.115 , pp. 751-763
    • Metivier, R.1    Penot, G.2    Hubner, M.R.3    Reid, G.4    Brand, H.5    Kos, M.6    Gannon, F.7
  • 18
    • 0035793376 scopus 로고    scopus 로고
    • Protein dynamics: Implications for nuclear architecture and gene expression
    • Misteli T (2001) Protein dynamics: implications for nuclear architecture and gene expression. Science 291: 843-847
    • (2001) Science , vol.291 , pp. 843-847
    • Misteli, T.1
  • 20
    • 0023176085 scopus 로고
    • An inducible transcription factor activates expression of human immunodeficiency virus in T cells
    • Nabel G, Baltimore D (1987) An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 326: 711-713
    • (1987) Nature , vol.326 , pp. 711-713
    • Nabel, G.1    Baltimore, D.2
  • 21
    • 1942502820 scopus 로고    scopus 로고
    • Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling
    • Nagaich AK, Walker DA, Wolford R, Hager GL (2004) Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling. Mol Cell 14: 163-174
    • (2004) Mol Cell , vol.14 , pp. 163-174
    • Nagaich, A.K.1    Walker, D.A.2    Wolford, R.3    Hager, G.L.4
  • 22
    • 18244379306 scopus 로고    scopus 로고
    • Interactions of NF-κB with chromatin: The art of being at the right place at the right time
    • Natoli G, Saccani S, Bosisio D, Marazzi I (2005) Interactions of NF-κB with chromatin: the art of being at the right place at the right time. Nat Immunol 6: 439-445
    • (2005) Nat Immunol , vol.6 , pp. 439-445
    • Natoli, G.1    Saccani, S.2    Bosisio, D.3    Marazzi, I.4
  • 23
    • 0030614504 scopus 로고    scopus 로고
    • Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator
    • Perkins ND, Felzien LK, Betts JC, Leung K, Beach DH, Nabel GJ (1997) Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator. Science 275: 523-527
    • (1997) Science , vol.275 , pp. 523-527
    • Perkins, N.D.1    Felzien, L.K.2    Betts, J.C.3    Leung, K.4    Beach, D.H.5    Nabel, G.J.6
  • 24
    • 1642377367 scopus 로고    scopus 로고
    • Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy
    • Phair RD, Gorski SA, Misteli T (2004a) Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy. Methods Enzymol 375: 393-414
    • (2004) Methods Enzymol , vol.375 , pp. 393-414
    • Phair, R.D.1    Gorski, S.A.2    Misteli, T.3
  • 25
    • 3042760021 scopus 로고    scopus 로고
    • Global nature of dynamic protein-chromatin interactions in vivo: Three-dimensional genome scanning and dynamic interaction networks of chromatin proteins
    • Phair RD, Scaffidi P, Elbi C, Vecerova J, Dey A, Ozato K, Brown DT, Hager GL, Bustin M, Misteli T (2004b) Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Mol Cell Biol 24: 6393-6402
    • (2004) Mol Cell Biol , vol.24 , pp. 6393-6402
    • Phair, R.D.1    Scaffidi, P.2    Elbi, C.3    Vecerova, J.4    Dey, A.5    Ozato, K.6    Brown, D.T.7    Hager, G.L.8    Bustin, M.9    Misteli, T.10
  • 27
    • 0030461543 scopus 로고    scopus 로고
    • In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition
    • Robinett CC, Straight A, Li G, Willhelm C, Sudlow G, Murray A, Belmont AS (1996) In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition. J Cell Biol 135: 1685-1700
    • (1996) J Cell Biol , vol.135 , pp. 1685-1700
    • Robinett, C.C.1    Straight, A.2    Li, G.3    Willhelm, C.4    Sudlow, G.5    Murray, A.6    Belmont, A.S.7
  • 28
    • 3142771914 scopus 로고    scopus 로고
    • Degradation of promoter-bound p65/RelA Is essential for the prompt termination of the NF-κB response
    • Saccani S, Marazzi I, Beg AA, Natoli G (2004) Degradation of promoter-bound p65/RelA Is essential for the prompt termination of the NF-κB response. J Exp Med 200: 107-113
    • (2004) J Exp Med , vol.200 , pp. 107-113
    • Saccani, S.1    Marazzi, I.2    Beg, A.A.3    Natoli, G.4
  • 29
    • 0035908126 scopus 로고    scopus 로고
    • Two waves of NF-κB recruitment to target promoters
    • Saccani S, Pantano S, Natoli G (2001) Two waves of NF-κB recruitment to target promoters. J Exp Med 193: 1351-1359
    • (2001) J Exp Med , vol.193 , pp. 1351-1359
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 30
    • 0038771214 scopus 로고    scopus 로고
    • Modulation of NF-κB activity by exchange of dimers
    • Saccani S, Pantano S, Natoli G (2003) Modulation of NF-κB activity by exchange of dimers. Mol Cell 11: 1563-1574
    • (2003) Mol Cell , vol.11 , pp. 1563-1574
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 32
    • 0141816852 scopus 로고    scopus 로고
    • Amplification of plasmids containing a mammalian replication initiation region is mediated by controllable conflict between replication and transcription
    • Shimizu N, Hashizume T, Shingaki K, Kawamoto JK (2003) Amplification of plasmids containing a mammalian replication initiation region is mediated by controllable conflict between replication and transcription. Cancer Res 63: 5281-5290
    • (2003) Cancer Res , vol.63 , pp. 5281-5290
    • Shimizu, N.1    Hashizume, T.2    Shingaki, K.3    Kawamoto, J.K.4
  • 33
    • 0035476928 scopus 로고    scopus 로고
    • Plasmids with a mammalian replication origin and a matrix attachment region initiate the event similar to gene amplification
    • Shimizu N, Miura Y, Sakamoto Y, Tsutsui K (2001) Plasmids with a mammalian replication origin and a matrix attachment region initiate the event similar to gene amplification. Cancer Res 61: 6987-6990
    • (2001) Cancer Res , vol.61 , pp. 6987-6990
    • Shimizu, N.1    Miura, Y.2    Sakamoto, Y.3    Tsutsui, K.4
  • 34
    • 12144290835 scopus 로고    scopus 로고
    • Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes
    • Stavreva DA, Muller WG, Hager GL, Smith CL, McNally JG (2004) Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes. Mol Cell Biol 24: 2682-2697
    • (2004) Mol Cell Biol , vol.24 , pp. 2682-2697
    • Stavreva, D.A.1    Muller, W.G.2    Hager, G.L.3    Smith, C.L.4    McNally, J.G.5
  • 35
    • 0033841301 scopus 로고    scopus 로고
    • Mammalian cell lines expressing functional RNA polymerase II tagged with the green fluorescent protein
    • Sugaya K, Vigneron M, Cook PR (2000) Mammalian cell lines expressing functional RNA polymerase II tagged with the green fluorescent protein. J Cell Sci 113 (Part 15): 2679-2683
    • (2000) J Cell Sci , vol.113 , Issue.15 PART , pp. 2679-2683
    • Sugaya, K.1    Vigneron, M.2    Cook, P.R.3
  • 36
    • 0028986193 scopus 로고
    • NF-κB: A lesson in family values
    • Thanos D, Maniatis T (1995a) NF-κB: a lesson in family values. Cell 80: 529-532
    • (1995) Cell , vol.80 , pp. 529-532
    • Thanos, D.1    Maniatis, T.2
  • 37
    • 0029617947 scopus 로고
    • Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome
    • Thanos D, Maniatis T (1995b) Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome. Cell 83: 1091-1100
    • (1995) Cell , vol.83 , pp. 1091-1100
    • Thanos, D.1    Maniatis, T.2
  • 38
    • 0025200592 scopus 로고
    • The 65-kD subunit of NF-κB is a receptor for IκB and a modulator of DNA-binding specificity
    • Urban MB, Baeuerle PA (1990) The 65-kD subunit of NF-κB is a receptor for IκB and a modulator of DNA-binding specificity. Genes Dev 4: 1975-1984
    • (1990) Genes Dev , vol.4 , pp. 1975-1984
    • Urban, M.B.1    Baeuerle, P.A.2
  • 39
    • 0033527448 scopus 로고    scopus 로고
    • The nuclear factor-κB engages CBP/p300 andhistone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter
    • Vanden Berghe W, De Bosscher K, Boone E, Plaisance S, Haegeman G (1999) The nuclear factor-κB engages CBP/p300 andhistone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter. J Biol Chem 274: 32091-32098
    • (1999) J Biol Chem , vol.274 , pp. 32091-32098
    • Vanden Berghe, W.1    De Bosscher, K.2    Boone, E.3    Plaisance, S.4    Haegeman, G.5
  • 41
    • 0028060550 scopus 로고
    • A striking similarity in the organization of the E-selectin and β-interferon gene promoters
    • Whitley MZ, Thanos D, Read MA, Maniatis T, Collins T (1994) A striking similarity in the organization of the E-selectin and β-interferon gene promoters. Mol Cell Biol 14: 6464-6475
    • (1994) Mol Cell Biol , vol.14 , pp. 6464-6475
    • Whitley, M.Z.1    Thanos, D.2    Read, M.A.3    Maniatis, T.4    Collins, T.5
  • 42
    • 0033152497 scopus 로고    scopus 로고
    • The role of HMG I(Y) in the assembly and function of the IFN-β enhanceosome
    • Yie J, Merika M, Munshi N, Chen G, Thanos D (1999) The role of HMG I(Y) in the assembly and function of the IFN-β enhanceosome. EMBO J 18: 3074-3089
    • (1999) EMBO J , vol.18 , pp. 3074-3089
    • Yie, J.1    Merika, M.2    Munshi, N.3    Chen, G.4    Thanos, D.5
  • 43
    • 0025304791 scopus 로고
    • Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA
    • Zabel U, Baeuerle PA (1990) Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA. Cell 61: 255-265
    • (1990) Cell , vol.61 , pp. 255-265
    • Zabel, U.1    Baeuerle, P.A.2
  • 44
    • 0032039076 scopus 로고    scopus 로고
    • Phosphorylation of NF-κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
    • Zhong H, Voll RE, Ghosh S (1998) Phosphorylation of NF-κB p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol Cell 1: 661-671
    • (1998) Mol Cell , vol.1 , pp. 661-671
    • Zhong, H.1    Voll, R.E.2    Ghosh, S.3


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