Immunoglobulin VH gene diversity and somatic hypermutation during SIV infection of rhesus macaques

Immunogenetics

Volumn 67, Issue 7, 2015, Pages 355-370

  Guo, Kejun ^a   Halemano, Kalani ^a   Schmitt, Kimberly ^b,d   Katuwal, Miki ^b   Wang, Yaqiong ^b   Harper, Michael S ^a   Heilman, Karl J ^a   Kuwata, Takeo ^c   Stephens, Edward B ^b   Santiago, Mario L ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c KUMAMOTO UNIVERSITY   (Japan)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Antibody repertoire; APOBEC3G; Deaminase; Rhesus macaque; Simian immunodeficiency virus; Somatic hypermutation

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN HEAVY CHAIN; MMUNOGLOBULIN V H1; MMUNOGLOBULIN V H3; MMUNOGLOBULIN V H4; UNCLASSIFIED DRUG; CYTIDINE DEAMINASE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOGLOBULIN VARIABLE REGION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4 CD8 RATIO; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DEAMINATION; DISEASE COURSE; GENE EXPRESSION; GENETIC VARIABILITY; GERMLINE MUTATION; HUMORAL IMMUNITY; LIMIT OF DETECTION; LONGITUDINAL STUDY; MOLECULAR DYNAMICS; MUTATION RATE; NEXT GENERATION SEQUENCING; NONHUMAN; PHYLOGENETIC TREE; PRIORITY JOURNAL; RHESUS MONKEY; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC HYPERMUTATION; STOP CODON; VIRUS LOAD; ANIMAL; ANTIBODY SPECIFICITY; B LYMPHOCYTE; DNA SEQUENCE; GENE FREQUENCY; GENETICS; HIGH THROUGHPUT SEQUENCING; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; NUCLEOTIDE SEQUENCE;

LENTIVIRUS; MACACA MULATTA; SIMIAN IMMUNODEFICIENCY VIRUS;

ANIMALS; ANTIBODY DIVERSITY; B-LYMPHOCYTES; BASE SEQUENCE; CYTIDINE DEAMINASE; GENE FREQUENCY; GENETIC VARIATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN M; IMMUNOGLOBULIN VARIABLE REGION; MACACA MULATTA; SEQUENCE ANALYSIS, DNA; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN;

EID: 84930537368     PISSN: 00937711     EISSN: 14321211     Source Type: Journal    
DOI: 10.1007/s00251-015-0844-3     Document Type: Article

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