Tetherin upregulation in simian immunodeficiency virus-infected macaques

Journal of Virology

Volumn 87, Issue 24, 2013, Pages 13917-13921

  Rahmberg, Andrew R ^a   Neidermyer Jr , William J ^a   Breed, Matthew W ^b   Alvarez, Xavier ^b   Midkiff, Cecily C ^b   Piatak, Michael ^c   Lifson, Jeffrey D ^c   Evans, David T ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b TULANE NATIONAL PRIMATE RESEARCH CENTER   (United States)

^c SAIC FREDERICK INC   (United States)

^d UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; MEMBRANE PROTEIN; TETHERIN PROTEIN; UNCLASSIFIED DRUG; VIRUS RNA;

ANIMAL CELL; ANTIGEN DETECTION; ARTICLE; CCR5+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; INFECTION; INNATE IMMUNITY; LONGITUDINAL STUDY; LYMPHOCYTE SUBPOPULATION; MEMORY T LYMPHOCYTE; NONHUMAN; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REGULATORY MECHANISM; RHESUS MONKEY; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; T LYMPHOCYTE; TARGET CELL; UPREGULATION; VIREMIA; VIRUS INDUCTION; VIRUS INFECTION; VIRUS LOAD; VIRUS REPLICATION;

ANIMALS; ANTIGENS, CD; MACACA; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; UP-REGULATION;

EID: 84888049331     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01757-13     Document Type: Article

References (29)

1. Van Damme N, Goff D, Katsura C, Jorgenson RL, Mitchell R, Johnson M, Stephens EB, Guatelli J. 2008. The interferon-induced protein BST-2/CD317 restricts release of virions from infected cells and is downregulated from the cell surface by HIV-1 Vpu. Cell Host Microbe 3:245-252.
2. Neil SJD, Zang T, Bieniasz PD. 2008. Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature 451:425-430.
3. Jouvenet N, Neil SJD, Zhadina M, Zang T, Kratovac Z, Lee Y, McNatt M, Hatziioannou T, Bieniasz PD. 2009. Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin. J. Virol. 83:1837-1844.
4. Kaletsky RL, Francica JR, Agrawal-Gamse C, Bates P. 2009. Tetherinmediated restriction of filovirus budding is antagonized by the Ebola glycoprotein. Proc. Natl. Acad. Sci. U.S.A. 106:2886-2891.
5. Mansouri M, Viswanathan K, Douglas JL, Hines J, Gustin J, Moses AV, Früh K. 2009. Molecular mechanism of BST2/tetherin downregulation by K5/MIR2 of Kaposi's sarcoma-associated herpesvirus. J. Virol. 83:9672-9681.
6. Sakuma T, Noda T, Urata S, Kawaoka Y, Yasuda J. 2009. Inhibition of Lassa and Marburg virus production by tetherin. J. Virol. 83:2382-2385.
7. Weidner JM, Jiang D, Pan X-B, Chang J, Block TM, Guo J-T. 2010. Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms. J. Virol. 84:12646-12657.
8. Mangeat B, Cavagliotti L, Lehmann M, Gers-Huber G, Kaur I, Thomas Y, Kaiser L, Piguet V. 2012. Influenza virus partially counteracts restriction imposed by tetherin/BST-2. J. Biol. Chem. 287:22015-22029.
9. Jia B, Serra-Moreno R, Neidermyer W, Rahmberg A, Mackey J, Fofana Ben I, Johnson WE, Westmoreland S, Evans DT. 2009. Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/ BST2. PLoS Pathog. 5:e1000429. doi:10.1371/journal.ppat.1000429.
10. Zhang F, Wilson SJ, Landford WC, Virgen B, Gregory D, Johnson MC, Munch J, Kirchhoff F, Bieniasz PD, Hatziioannou T. 2009. Nef proteins from simian immunodeficiency viruses are tetherin antagonists. Cell Host Microbe 6:54-67.
11. Le Tortorec A, Neil SJD. 2009. Antagonism to and intracellular sequestration of human tetherin by the human immunodeficiency virus type 2 envelope glycoprotein. J. Virol. 83:11966-11978.
12. Sauter D, Schindler M, Specht A, Landford WN, Münch J, Kim K-A, Votteler J, Schubert U, Bibollet-Ruche F, Keele BF, Takehisa J, Ogando Y, Ochsenbauer C, Kappes JC, Ayouba A, Peeters M, Learn GH, Shaw G, Sharp PM, Bieniasz P, Hahn BH, Hatziioannou T, Kirchhoff F. 2009. Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains. Cell Host Microbe 6:409-421.
13. Sauter D, Specht A, Kirchhoff F. 2010. Tetherin:holding on and letting go. Cell 141:392-398.
14. Evans DT, Serra-Moreno R, Singh RK, Guatelli JC. 2010. BST-2/ tetherin:a new component of the innate immune response to enveloped viruses. Trends Microbiol. 18:388-396.
15. Serra-Moreno R, Evans DT. 2012. Adaptation of human and simian immunodeficiency viruses for resistance to tetherin/BST-2. Curr. HIV Res. 10:277-282.
16. Liberatore RA, Bieniasz PD. 2011. Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo. Proc. Natl. Acad. Sci. U.S.A. 108:18097-18101.
17. Cocka LJ, Bates P. 2012. Identification of alternatively translated tetherin isoforms with differing antiviral and signaling activities. PLoS Pathog. 8:e1002931. doi:10.1371/journal.ppat.1002931.
18. Galão RP, Le Tortorec A, Pickering S, Kueck T, Neil SJD. 2012. Innate sensing of HIV-1 assembly by Tetherin induces NFκB-dependent proinflammatory responses. Cell Host Microbe 12:633-644.
19. Cao W, Bover L, Cho M, Wen X, Hanabuchi S, Bao M, Rosen DB, Wang Y-H, Shaw JL, Du Q, Li C, Arai N, Yao Z, Lanier LL, Liu Y-J. 2009. Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction. J. Exp. Med. 206:1603-1614.
20. Pillai SK, Abdel-Mohsen M, Guatelli J, Skasko M, Monto A, Fujimoto K, Yukl S, Greene WC, Kovari H, Rauch A, Fellay J, Battegay M, Hirschel B, Witteck A, Bernasconi E, Ledergerber B, Gunthard HF, Wong JK, Günthard HF. 2012. Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo. Proc. Natl. Acad. Sci. U.S.A. 109:2-7.
21. Homann S, Smith D, Little S, Richman D, Guatelli J. 2011. Upregulation of BST-2/tetherin by HIV infection in vivo. J. Virol. 85:10659-10668.
22. Mattapallil JJ, Douek DC, Hill B, Nishimura Y, Martin M, Roederer M. 2005. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 434:1093-1097.
23. Brown KN, Wijewardana V, Liu X, Barratt-Boyes SM. 2009. Rapid influx and death of plasmacytoid dendritic cells in lymph nodes mediate depletion in acute simian immunodeficiency virus infection. PLoS Pathog. 5:e1000413. doi:10.1371/journal.ppat.1000413.
24. Reeves RK, Evans TI, Gillis J, Wong FE, Kang G, Li Q, Johnson RP. 2012. SIV infection induces accumulation of plasmacytoid dendritic cells in the gut mucosa. J. Infect. Dis. 206:1462-1468.
25. Chahroudi A, Bosinger SE, Vanderford TH, Paiardini M, Silvestri G. 2012. Natural SIV hosts:showing AIDS the door. Science 335:1188-1193.
26. Jacquelin B, Mayau V, Targat B, Liovat AS, Kunkel D, Petitjean G, Dillies M, Roques P, Butor C, Silvestri G, Giavedoni L, Lebon P, Barré-Sinoussi F, Benecke A, Müller-Trutwin M. 2009. Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response. J. Clin. Invest. 119:3544-3555.
27. Alexander L, Illyinskii P, Lang S, Means R, Lifson J, Mansfield K, Desrosiers R. 2003. Determinants of increased replicative capacity of serially passaged simian immunodeficiency virus with nef deleted in rhesus monkeys. J. Virol. 77:6823-6835.
28. Serra-Moreno R, Jia B, Breed M, Alvarez X, Evans DT. 2011. Compensatory changes in the cytoplasmic tail of gp41 confer resistance to tetherin/ BST-2 in a pathogenic nef-deleted SIV. Cell Host Microbe 9:46-57.
29. Tokarev A, Suarez M, Kwan W, Fitzpatrick K, Singh R, Guatelli J. 2013. Stimulation of NF-κB activity by the HIV restriction factor BST2. J. Virol. 87:2046-2057.