메뉴 건너뛰기




Volumn 85, Issue 5, 2011, Pages 2189-2200

Acquisition of host-derived CD40L by HIV-1 in vivo and its functional consequences in the B-cell compartment

Author keywords

[No Author keywords available]

Indexed keywords

A20 PROTEIN; ACTIVATION INDUCED CYTIDINE DEAMINASE; AMPHOTERICIN B DEOXYCHOLATE; B7 ANTIGEN; CD23 ANTIGEN; CD40 ANTIGEN; CD40 LIGAND; CD40 LIGAND AGONIST; CHEMOKINE RECEPTOR; FAS ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOTOXIN; LYMPHOTOXIN BETA; MACROPHAGE DERIVED CHEMOKINE; MITOGEN ACTIVATED PROTEIN 2 KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TNIP1 PROTEIN; TRANSCRIPTION FACTOR NFKB1; TRANSCRIPTION FACTOR NFKBIA; TRANSCRIPTION FACTOR NFKBIE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UNCLASSIFIED DRUG;

EID: 79551707880     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01993-10     Document Type: Article
Times cited : (45)

References (58)
  • 1
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi, A., et al. 1986. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59:284-291. (Pubitemid 16013975)
    • (1986) Journal of Virology , vol.59 , Issue.2 , pp. 284-291
    • Adachi, A.1    Gendelman, H.E.2    Koenig, S.3
  • 2
    • 0032428331 scopus 로고    scopus 로고
    • Modulation of life and death by the TNF receptor superfamily
    • Baker, S. J., and E. P. Reddy. 1998. Modulation of life and death by the TNF receptor superfamily. Oncogene 17:3261-3270.
    • (1998) Oncogene , vol.17 , pp. 3261-3270
    • Baker, S.J.1    Reddy, E.P.2
  • 3
    • 0027260343 scopus 로고
    • The maturation of the immune response
    • Berek, C., and M. Ziegner. 1993. The maturation of the immune response. Immunol. Today 14:400-404.
    • (1993) Immunol. Today , vol.14 , pp. 400-404
    • Berek, C.1    Ziegner, M.2
  • 4
    • 0034823202 scopus 로고    scopus 로고
    • Signaling by CD40 and its mimics in B cell activation
    • Bishop, G. A., and B. S. Hostager. 2001. Signaling by CD40 and its mimics in B cell activation. Immunol. Res. 24:97-109.
    • (2001) Immunol. Res. , vol.24 , pp. 97-109
    • Bishop, G.A.1    Hostager, B.S.2
  • 5
    • 0036147255 scopus 로고    scopus 로고
    • Presence of host ICAM-1 in laboratory and clinical strains of human immunodeficiency virus type 1 increases virus infectivity and CD4(+)-T-cell depletion in human lymphoid tissue, a major site of replication in vivo
    • Bounou, S., J. E. Leclerc, and M. J. Tremblay. 2002. Presence of host ICAM-1 in laboratory and clinical strains of human immunodeficiency virus type 1 increases virus infectivity and CD4(+)-T-cell depletion in human lymphoid tissue, a major site of replication in vivo. J. Virol. 76:1004-1014.
    • (2002) J. Virol. , vol.76 , pp. 1004-1014
    • Bounou, S.1    Leclerc, J.E.2    Tremblay, M.J.3
  • 6
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley, J. M., et al. 2006. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat. Med. 12:1365-1371.
    • (2006) Nat. Med. , vol.12 , pp. 1365-1371
    • Brenchley, J.M.1
  • 7
    • 0025887327 scopus 로고
    • T-cell-mediated activation of B cells
    • Burstein, H. J., and A. K. Abbas. 1991. T-cell-mediated activation of B cells. Curr. Opin. Immunol. 3:345-349.
    • (1991) Curr. Opin. Immunol. , vol.3 , pp. 345-349
    • Burstein, H.J.1    Abbas, A.K.2
  • 9
    • 0029943397 scopus 로고    scopus 로고
    • The amount of host HLA-DR proteins acquired by HIV-1 is virus strain- And cell type-specific
    • DOI 10.1006/viro.1996.0206
    • Cantin, R., J. F. Fortin, and M. Tremblay. 1996. The amount of host HLA-DR proteins acquired by HIV-1 is virus strain- and cell type-specific. Virology 218:372-381. (Pubitemid 26163831)
    • (1996) Virology , vol.218 , Issue.2 , pp. 372-381
    • Cantin, R.1    Fortin, J.-F.2    Tremblay, M.3
  • 10
    • 0031832783 scopus 로고    scopus 로고
    • Cytokine regulation of secondary lymphoid organ development
    • Chaplin, D. D., and Y. Fu. 1998. Cytokine regulation of secondary lymphoid organ development. Curr. Opin. Immunol. 10:289-297.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 289-297
    • Chaplin, D.D.1    Fu, Y.2
  • 11
    • 0028298767 scopus 로고
    • Nef protein of HIV-1 has B-cell stimulatory activity
    • Chirmule, N., N. Oyaizu, C. Saxinger, and S. Pahwa. 1994. Nef protein of HIV-1 has B-cell stimulatory activity. AIDS 8:733-734.
    • (1994) AIDS , vol.8 , pp. 733-734
    • Chirmule, N.1    Oyaizu, N.2    Saxinger, C.3    Pahwa, S.4
  • 12
    • 2542505512 scopus 로고    scopus 로고
    • Downregulation of CXCR5 in CD27- B cells of HIV-1 infected patients
    • Chong, Y., et al. 2004. Downregulation of CXCR5 in CD27- B cells of HIV-1 infected patients. J. Med. Virol. 73:362-367.
    • (2004) J. Med. Virol. , vol.73 , pp. 362-367
    • Chong, Y.1
  • 13
    • 14844283405 scopus 로고    scopus 로고
    • Differential downstream effects of CD40 ligation mediated by membrane or soluble CD40L and agonistic Ab: A study on purified human B cells
    • Cognasse, F., et al. 2005. Differential downstream effects of CD40 ligation mediated by membrane or soluble CD40L and agonistic Ab: a study on purified human B cells. Int. J. Immunopathol. Pharmacol. 18:65-74.
    • (2005) Int. J. Immunopathol. Pharmacol. , vol.18 , pp. 65-74
    • Cognasse, F.1
  • 14
    • 0038005018 scopus 로고    scopus 로고
    • DAVID: Database for annotation, visualization, and integrated discovery
    • Dennis, G., jr., et al. 2003. DAVID: database for annotation, visualization, and integrated discovery. Genome Biol. 4:P3.
    • (2003) Genome Biol , vol.4 , pp. 3
    • Dennis Jr., G.1
  • 15
    • 0036428815 scopus 로고    scopus 로고
    • Lymphocyte traffic in lymphoid organ neogenesis: Differential roles of Ltalpha and LTalphabeta
    • Drayton, D. L., et al. 2002. Lymphocyte traffic in lymphoid organ neogenesis: differential roles of Ltalpha and LTalphabeta. Adv. Exp. Med. Biol. 512:43-48.
    • (2002) Adv. Exp. Med. Biol. , vol.512 , pp. 43-48
    • Drayton, D.L.1
  • 16
    • 33745460379 scopus 로고    scopus 로고
    • Ultrasensitive monitoring of HIV-1 viral load by a low-cost real-time reverse transcription-PCR assay with internal control for the 5′ long terminal repeat domain
    • Drosten, C., et al. 2006. Ultrasensitive monitoring of HIV-1 viral load by a low-cost real-time reverse transcription-PCR assay with internal control for the 5′ long terminal repeat domain. Clin. Chem. 52:1258-1266.
    • (2006) Clin. Chem. , vol.52 , pp. 1258-1266
    • Drosten, C.1
  • 17
    • 0041474807 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase: A dual role in class-switch recombination and somatic hypermutation
    • Durandy, A. 2003. Activation-induced cytidine deaminase: a dual role in class-switch recombination and somatic hypermutation. Eur. J. Immunol. 33:2069-2073.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2069-2073
    • Durandy, A.1
  • 18
    • 77955362036 scopus 로고    scopus 로고
    • CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes
    • Epeldegui, M., et al. 2010. CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes. PLoS One 5:e11448.
    • (2010) PLoS One , vol.5
    • Epeldegui, M.1
  • 19
    • 0036245963 scopus 로고    scopus 로고
    • Spontaneous secretion of immunoglobulins and anti-HIV-1 antibodies by in vivo activated B lymphocytes from HIV-1-infected subjects: Monocyte and natural killer cell requirement for in vitro terminal differentiation into plasma cells
    • Fournier, A. M., et al. 2002. Spontaneous secretion of immunoglobulins and anti-HIV-1 antibodies by in vivo activated B lymphocytes from HIV-1-infected subjects: monocyte and natural killer cell requirement for in vitro terminal differentiation into plasma cells. Clin. Immunol. 103:98-109.
    • (2002) Clin. Immunol. , vol.103 , pp. 98-109
    • Fournier, A.M.1
  • 20
    • 0035874499 scopus 로고    scopus 로고
    • A potential role for interleukin-7 in T-cell homeostasis
    • Fry, T. J., et al. 2001. A potential role for interleukin-7 in T-cell homeostasis. Blood 97:2983-2990.
    • (2001) Blood , vol.97 , pp. 2983-2990
    • Fry, T.J.1
  • 21
    • 0031214948 scopus 로고    scopus 로고
    • Distinctive characteristics of germinal center B cells
    • Han, S., B. Zheng, Y. Takahashi, and G. Kelsoe. 1997. Distinctive characteristics of germinal center B cells. Semin. Immunol. 9:255-260.
    • (1997) Semin. Immunol. , vol.9 , pp. 255-260
    • Han, S.1    Zheng, B.2    Takahashi, Y.3    Kelsoe, G.4
  • 22
    • 33646045632 scopus 로고    scopus 로고
    • HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptors
    • He, B., et al. 2006. HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptors. J. Immunol. 176:3931-3941. (Pubitemid 44264370)
    • (2006) Journal of Immunology , vol.176 , Issue.7 , pp. 3931-3941
    • He, B.1    Qiao, X.2    Klasse, P.J.3    Chiu, A.4    Chadburn, A.5    Knowles, D.M.6    Moore, J.P.7    Cerutti, A.8
  • 23
    • 0032574782 scopus 로고    scopus 로고
    • CD40 ligand (CD154) stimulation of macrophages to produce HIV-1-suppressive beta-chemokines
    • Kornbluth, R. S., K. Kee, and D. D. Richman. 1998. CD40 ligand (CD154) stimulation of macrophages to produce HIV-1-suppressive beta-chemokines. Proc. Natl. Acad. Sci. U. S. A. 95:5205-5210.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 5205-5210
    • Kornbluth, R.S.1    Kee, K.2    Richman, D.D.3
  • 24
    • 0029946329 scopus 로고    scopus 로고
    • Functions of CD40 and its ligand, gp39 (CD40L)
    • Laman, J. D., E. Claassen, and R. J. Noelle. 1996. Functions of CD40 and its ligand, gp39 (CD40L). Crit. Rev. Immunol. 16:59-108.
    • (1996) Crit. Rev. Immunol. , vol.16 , pp. 59-108
    • Laman, J.D.1    Claassen, E.2    Noelle, R.J.3
  • 25
    • 0020516865 scopus 로고
    • Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome
    • Lane, H. C., et al. 1983. Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. N. Engl. J. Med. 309:453-458.
    • (1983) N. Engl. J. Med. , vol.309 , pp. 453-458
    • Lane, H.C.1
  • 26
    • 1842555407 scopus 로고    scopus 로고
    • Transcription-coupled mutagenesis by the DNA deaminase AID
    • Larson, E. D., and N. Maizels. 2004. Transcription-coupled mutagenesis by the DNA deaminase AID. Genome Biol. 5:211.
    • (2004) Genome Biol , vol.5 , pp. 211
    • Larson, E.D.1    Maizels, N.2
  • 27
    • 0033771053 scopus 로고    scopus 로고
    • Incorporation of HLA-DR into the envelope of human immunodeficiency virus type 1 in vivo: Correlation with stage of disease and presence of opportunistic infection
    • Lawn, S. D., and S. T. Butera. 2000. Incorporation of HLA-DR into the envelope of human immunodeficiency virus type 1 in vivo: correlation with stage of disease and presence of opportunistic infection. J. Virol. 74:10256-10259.
    • (2000) J. Virol. , vol.74 , pp. 10256-10259
    • Lawn, S.D.1    Butera, S.T.2
  • 28
    • 0030679623 scopus 로고    scopus 로고
    • Agonistic activity of a CD40-specific single-chain Fv constructed from the variable regions of mAb G28-5
    • Ledbetter, J. A., et al. 1997. Agonistic activity of a CD40-specific single-chain Fv constructed from the variable regions of mAb G28-5. Crit. Rev. Immunol. 17:427-435.
    • (1997) Crit. Rev. Immunol. , vol.17 , pp. 427-435
    • Ledbetter, J.A.1
  • 29
    • 0028566985 scopus 로고
    • Agonistic and antagonistic properties of CD40 mAb G28-5 are dependent on binding valency
    • Ledbetter, J. A., L. S. Grosmaire, D. Hollenbaugh, A. Aruffo, and S. G. Nadler. 1994. Agonistic and antagonistic properties of CD40 mAb G28-5 are dependent on binding valency. Circ. Shock 44:67-72.
    • (1994) Circ. Shock , vol.44 , pp. 67-72
    • Ledbetter, J.A.1    Grosmaire, L.S.2    Hollenbaugh, D.3    Aruffo, A.4    Nadler, S.G.5
  • 30
    • 68049135892 scopus 로고    scopus 로고
    • Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection
    • Levesque, M. C., et al. 2009. Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. PLoS Med. 6:e1000107.
    • (2009) PLoS Med , vol.6
    • Levesque, M.C.1
  • 31
    • 20244373953 scopus 로고    scopus 로고
    • Compromised B cell responses to influenza vaccination in HIV-infected individuals
    • Malaspina, A., et al. 2005. Compromised B cell responses to influenza vaccination in HIV-infected individuals. J. Infect. Dis. 191:1442-1450.
    • (2005) J. Infect. Dis. , vol.191 , pp. 1442-1450
    • Malaspina, A.1
  • 32
    • 53549103852 scopus 로고    scopus 로고
    • Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections
    • Mandl, J. N., et al. 2008. Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. Nat. Med. 14:1077-1087.
    • (2008) Nat. Med. , vol.14 , pp. 1077-1087
    • Mandl, J.N.1
  • 34
    • 2942560774 scopus 로고    scopus 로고
    • HLA-DR, ICAM-1, CD40, CD40L, and CD86 are incorporated to a similar degree into clinical human immunodeficiency virus type 1 variants expanded in natural reservoirs such as peripheral blood mononuclear cells and human lymphoid tissue cultured ex vivo
    • Martin, G., and M. J. Tremblay. 2004. HLA-DR, ICAM-1, CD40, CD40L, and CD86 are incorporated to a similar degree into clinical human immunodeficiency virus type 1 variants expanded in natural reservoirs such as peripheral blood mononuclear cells and human lymphoid tissue cultured ex vivo. Clin. Immunol. 111:275-285.
    • (2004) Clin. Immunol. , vol.111 , pp. 275-285
    • Martin, G.1    Tremblay, M.J.2
  • 35
    • 0033170023 scopus 로고    scopus 로고
    • Role of TNF ligand and receptor family in the lymphoid organogenesis defined by gene targeting
    • Matsumoto, M. 1999. Role of TNF ligand and receptor family in the lymphoid organogenesis defined by gene targeting. J. Med. Investig. 46:141-150.
    • (1999) J. Med. Investig. , vol.46 , pp. 141-150
    • Matsumoto, M.1
  • 36
    • 0030938635 scopus 로고    scopus 로고
    • Lymphotoxinalpha-deficient and TNF receptor-I-deficient mice define developmental and functional characteristics of germinal centers
    • Matsumoto, M., Y. X. Fu, H. Molina, and D. D. Chaplin. 1997. Lymphotoxinalpha-deficient and TNF receptor-I-deficient mice define developmental and functional characteristics of germinal centers. Immunol. Rev. 156:137-144.
    • (1997) Immunol. Rev. , vol.156 , pp. 137-144
    • Matsumoto, M.1    Fu, Y.X.2    Molina, H.3    Chaplin, D.D.4
  • 37
    • 0026333671 scopus 로고
    • Cytokines and HIV infection: Is AIDS a tumor necrosis factor disease?
    • Matsuyama, T., N. Kobayashi, and N. Yamamoto. 1991. Cytokines and HIV infection: is AIDS a tumor necrosis factor disease? AIDS 5:1405-1417.
    • (1991) AIDS , vol.5 , pp. 1405-1417
    • Matsuyama, T.1    Kobayashi, N.2    Yamamoto, N.3
  • 38
    • 0032504086 scopus 로고    scopus 로고
    • Tumor necrosis factor beta and soluble APO-1/Fas independently predict progression to AIDS in HIV-seropositive patients
    • Medrano, F. J., et al. 1998. Tumor necrosis factor beta and soluble APO-1/Fas independently predict progression to AIDS in HIV-seropositive patients. AIDS Res. Hum. Retrovir. 14:835-843.
    • (1998) AIDS Res. Hum. Retrovir. , vol.14 , pp. 835-843
    • Medrano, F.J.1
  • 39
    • 63149142646 scopus 로고    scopus 로고
    • B cells in HIV infection and disease
    • Moir, S., and A. S. Fauci. 2009. B cells in HIV infection and disease. Nat. Rev. Immunol. 9:235-245.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 235-245
    • Moir, S.1    Fauci, A.S.2
  • 40
    • 46049112339 scopus 로고    scopus 로고
    • Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals
    • Moir, S., et al. 2008. Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J. Exp. Med. 205:1797-1805.
    • (2008) J. Exp. Med. , vol.205 , pp. 1797-1805
    • Moir, S.1
  • 41
    • 17944373021 scopus 로고    scopus 로고
    • HIV-1 induces phenotypic and functional perturbations of B cells in chronically infected individuals
    • Moir, S., et al. 2001. HIV-1 induces phenotypic and functional perturbations of B cells in chronically infected individuals. Proc. Natl. Acad. Sci. U. S. A. 98:10362-10367.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 10362-10367
    • Moir, S.1
  • 42
    • 0038623839 scopus 로고    scopus 로고
    • Perturbations in B cell responsiveness to CD4+ T cell help in HIV-infected individuals
    • Moir, S., et al. 2003. Perturbations in B cell responsiveness to CD4+ T cell help in HIV-infected individuals. Proc. Natl. Acad. Sci. U. S. A. 100:6057-6062.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 6057-6062
    • Moir, S.1
  • 43
    • 0027983655 scopus 로고
    • Cytokine patterns during the progression to AIDS
    • Mosmann, T. R. 1994. Cytokine patterns during the progression to AIDS. Science 265:193-194. (Pubitemid 24259912)
    • (1994) Science , vol.265 , Issue.5169 , pp. 193-194
    • Mosmann, T.R.1
  • 44
    • 0032533626 scopus 로고    scopus 로고
    • Possible role of interleukin-10 (IL-10) and CD40 ligand expression in the pathogenesis of hypergammaglobulinemia in human immunodeficiency virus infection: Modulation of IL-10 and Ig production after intravenous Ig infusion
    • Müller, F., P. Aukrust, I. Nordoy, and S. S. Froland. 1998. Possible role of interleukin-10 (IL-10) and CD40 ligand expression in the pathogenesis of hypergammaglobulinemia in human immunodeficiency virus infection: modulation of IL-10 and Ig production after intravenous Ig infusion. Blood 92:3721-3729.
    • (1998) Blood , vol.92 , pp. 3721-3729
    • Müller, F.1    Aukrust, P.2    Nordoy, I.3    Froland, S.S.4
  • 45
    • 0035138982 scopus 로고    scopus 로고
    • Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: Implications for T-cell homeostasis
    • Napolitano, L. A., et al. 2001. Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis. Nat. Med. 7:73-79.
    • (2001) Nat. Med. , vol.7 , pp. 73-79
    • Napolitano, L.A.1
  • 46
    • 0034821092 scopus 로고    scopus 로고
    • Potent antiretroviral therapy initiates normalization of hypergammaglobulinemia and a decline in HIV type 1-specific antibody responses
    • Notermans, D. W., et al. 2001. Potent antiretroviral therapy initiates normalization of hypergammaglobulinemia and a decline in HIV type 1-specific antibody responses. AIDS Res. Hum. Retrovir. 17:1003-1008.
    • (2001) AIDS Res. Hum. Retrovir. , vol.17 , pp. 1003-1008
    • Notermans, D.W.1
  • 47
    • 2542476167 scopus 로고    scopus 로고
    • CD40/CD154 interactions at the interface of tolerance and immunity
    • Quezada, S. A., L. Z. Jarvinen, E. F. Lind, and R. J. Noelle. 2004. CD40/CD154 interactions at the interface of tolerance and immunity. Annu. Rev. Immunol. 22:307-328.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 307-328
    • Quezada, S.A.1    Jarvinen, L.Z.2    Lind, E.F.3    Noelle, R.J.4
  • 48
    • 0025954319 scopus 로고
    • Recombinant gp120 specifically enhances tumor necrosis factor-alpha production and Ig secretion in B lymphocytes from HIV-infected individuals but not from seronegative donors
    • Rieckmann, P., G. Poli, C. H. Fox, J. H. Kehrl, and A. S. Fauci. 1991. Recombinant gp120 specifically enhances tumor necrosis factor-alpha production and Ig secretion in B lymphocytes from HIV-infected individuals but not from seronegative donors. J. Immunol. 147:2922-2927.
    • (1991) J. Immunol. , vol.147 , pp. 2922-2927
    • Rieckmann, P.1    Poli, G.2    Fox, C.H.3    Kehrl, J.H.4    Fauci, A.S.5
  • 49
    • 0026568269 scopus 로고
    • Human immunodeficiency virus infection induces both polyclonal and virus-specific B cell activation
    • Shirai, A., M. Cosentino, S. F. Leitman-Klinman, and D. M. Klinman. 1992. Human immunodeficiency virus infection induces both polyclonal and virus-specific B cell activation. J. Clin. Investig. 89:561-566.
    • (1992) J. Clin. Investig. , vol.89 , pp. 561-566
    • Shirai, A.1    Cosentino, M.2    Leitman-Klinman, S.F.3    Klinman, D.M.4
  • 50
    • 1242340424 scopus 로고    scopus 로고
    • Modulating the intestinal immune system: The role of lymphotoxin and GALT organs
    • DOI 10.1136/gut.2003.023671
    • Spahn, T. W., and T. Kucharzik. 2004. Modulating the intestinal immune system: the role of lymphotoxin and GALT organs. Gut 53:456-465. (Pubitemid 38241347)
    • (2004) Gut , vol.53 , Issue.3 , pp. 456-465
    • Spahn, T.W.1    Kucharzik, T.2
  • 51
    • 33749032139 scopus 로고    scopus 로고
    • Role of lymphotoxins in the development of Peyer's patches and mesenteric lymph nodes: Relevance to intestinal inflammation and treatment
    • Spahn, T. W., M. K. Muller, W. Domschke, and T. Kucharzik. 2006. Role of lymphotoxins in the development of Peyer's patches and mesenteric lymph nodes: relevance to intestinal inflammation and treatment. Ann. N. Y. Acad. Sci. 1072:187-193.
    • (2006) Ann. N. Y. Acad. Sci. , vol.1072 , pp. 187-193
    • Spahn, T.W.1    Muller, M.K.2    Domschke, W.3    Kucharzik, T.4
  • 55
    • 0025855437 scopus 로고
    • Altered production of tumour necrosis factors alpha and beta and interferon gamma by HIV-infected individuals
    • Vyakarnam, A., et al. 1991. Altered production of tumour necrosis factors alpha and beta and interferon gamma by HIV-infected individuals. Clin. Exp. Immunol. 84:109-115.
    • (1991) Clin. Exp. Immunol. , vol.84 , pp. 109-115
    • Vyakarnam, A.1
  • 56
    • 0025164734 scopus 로고
    • Tumour necrosis factors (alpha, beta) induced by HIV-1 in peripheral blood mononuclear cells potentiate virus replication
    • Vyakarnam, A., J. McKeating, A. Meager, and P. C. Beverley. 1990. Tumour necrosis factors (alpha, beta) induced by HIV-1 in peripheral blood mononuclear cells potentiate virus replication. AIDS 4:21-27.
    • (1990) AIDS , vol.4 , pp. 21-27
    • Vyakarnam, A.1    McKeating, J.2    Meager, A.3    Beverley, P.C.4
  • 57
    • 0030052281 scopus 로고    scopus 로고
    • Rearrangement/hypermutation/gene conversion: When, where and why?
    • Weill, J. C., and C. A. Reynaud. 1996. Rearrangement/hypermutation/gene conversion: when, where and why? Immunol. Today 17:92-97.
    • (1996) Immunol. Today , vol.17 , pp. 92-97
    • Weill, J.C.1    Reynaud, C.A.2
  • 58
    • 0031950699 scopus 로고    scopus 로고
    • HIV-induced IL-6/IL-10 dysregulation of CD4 cells is associated with defective B cell help and autoantibody formation against CD4 cells
    • Weimer, R., et al. 1998. HIV-induced IL-6/IL-10 dysregulation of CD4 cells is associated with defective B cell help and autoantibody formation against CD4 cells. Clin. Exp. Immunol. 111:20-29.
    • (1998) Clin. Exp. Immunol. , vol.111 , pp. 20-29
    • Weimer, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.