Conformational epitope consisting of the V3 and V4 loops as a target for potent and broad neutralization of simian immunodeficiency viruses

Journal of Virology

Volumn 87, Issue 10, 2013, Pages 5424-5436

  Kuwata, Takeo ^a   Takaki, Kaori ^a   Yoshimur, Kazuhisa ^b   Enomoto, Ikumi ^a   Wu, Fan ^c   Ourmanov, Ilnour ^c   Hirsch, Vanessa M ^c   Yokoyam, Masaru ^a,b   Sato, Hironori ^b   Matsushita, Shuzo ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; EPITOPE; GLYCOPROTEIN GP 120; IMMUNOGLOBULIN LAMBDA CHAIN; NEUTRALIZING ANTIBODY; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN BINDING; ANTIGEN RECOGNITION; ANTIGEN STRUCTURE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EPITOPE MAPPING; GENE MUTATION; IMMUNOASSAY; IMMUNOGLOBULIN VARIABLE REGION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN TARGETING; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; UNINDEXED SEQUENCE; VH3 GENE; VIRUS ENVELOPE; VIRUS GENE; VIRUS MUTANT; VIRUS NEUTRALIZATION; VIRUS STRAIN;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; DNA MUTATIONAL ANALYSIS; EPITOPE MAPPING; EPITOPES; MACACA; MEMBRANE GLYCOPROTEINS; MOLECULAR DYNAMICS SIMULATION; MUTATION, MISSENSE; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; VIRAL ENVELOPE PROTEINS;

EID: 84877336116     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00201-13     Document Type: Article

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