-
1
-
-
33846857963
-
Neogenin and repulsive guidance molecule signaling in the central nervous system
-
Yamashita, T., Mueller, B.K. & Hata, K. Neogenin and repulsive guidance molecule signaling in the central nervous system. Curr. Opin. Neurobiol. 17, 29-34 (2007).
-
(2007)
Curr. Opin. Neurobiol.
, vol.17
, pp. 29-34
-
-
Yamashita, T.1
Mueller, B.K.2
Hata, K.3
-
2
-
-
79955586868
-
Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates infammation
-
Mirakaj, V. et al. Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates infammation. Proc. Natl. Acad. Sci. USA 108, 6555-6560 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 6555-6560
-
-
Mirakaj, V.1
-
3
-
-
79953743514
-
RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis
-
Muramatsu, R. et al. RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis. Nat. Med. 17, 488-494 (2011).
-
(2011)
Nat. Med.
, vol.17
, pp. 488-494
-
-
Muramatsu, R.1
-
4
-
-
67649215234
-
Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms
-
Li, V.S. et al. Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms. Gastroenterology 137, 176-187 (2009).
-
(2009)
Gastroenterology
, vol.137
, pp. 176-187
-
-
Li, V.S.1
-
5
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou, G. et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat. Genet. 36, 77-82 (2004).
-
(2004)
Nat. Genet.
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
-
6
-
-
18544379947
-
RGM is a repulsive guidance molecule for retinal axons
-
Monnier, P.P. et al. RGM is a repulsive guidance molecule for retinal axons. Nature 419, 392-395 (2002).
-
(2002)
Nature
, vol.419
, pp. 392-395
-
-
Monnier, P.P.1
-
7
-
-
4143124603
-
Neogenin mediates the action of repulsive guidance molecule
-
Rajagopalan, S. et al. Neogenin mediates the action of repulsive guidance molecule. Nat. Cell Biol. 6, 756-762 (2004).
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 756-762
-
-
Rajagopalan, S.1
-
8
-
-
11144245556
-
Repulsive guidance molecule/neogenin: A novel ligand-receptor system playing multiple roles in neural development
-
Matsunaga, E. & Chedotal, A. Repulsive guidance molecule/neogenin: a novel ligand-receptor system playing multiple roles in neural development. Dev. Growth Differ. 46, 481-486 (2004).
-
(2004)
Dev. Growth Differ.
, vol.46
, pp. 481-486
-
-
Matsunaga, E.1
Chedotal, A.2
-
9
-
-
84879793105
-
Structure of the repulsive guidance molecule (RGM)-neogenin signaling hub
-
Bell, C.H. et al. Structure of the repulsive guidance molecule (RGM)-neogenin signaling hub. Science 341, 77-80 (2013).
-
(2013)
Science
, vol.341
, pp. 77-80
-
-
Bell, C.H.1
-
10
-
-
33646370235
-
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
-
Babitt, J.L. et al. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat. Genet. 38, 531-539 (2006).
-
(2006)
Nat. Genet.
, vol.38
, pp. 531-539
-
-
Babitt, J.L.1
-
11
-
-
20244375259
-
DRAGON, a bone morphogenetic protein co-receptor
-
Samad, T.A. et al. DRAGON, a bone morphogenetic protein co-receptor. J. Biol. Chem. 280, 14122-14129 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 14122-14129
-
-
Samad, T.A.1
-
12
-
-
23844456919
-
Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor
-
Babitt, J.L. et al. Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor. J. Biol. Chem. 280, 29820-29827 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29820-29827
-
-
Babitt, J.L.1
-
13
-
-
77951086900
-
Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis
-
Lee, D.H. et al. Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. Blood 115, 3136-3145 (2010).
-
(2010)
Blood
, vol.115
, pp. 3136-3145
-
-
Lee, D.H.1
-
14
-
-
69249118614
-
Hemojuvelin-neogenin interaction is required for bone morphogenic protein-4-induced hepcidin expression
-
Zhang, A.S., Yang, F. , Wang, J., Tsukamoto, H. & Enns, C.A. Hemojuvelin-neogenin interaction is required for bone morphogenic protein-4-induced hepcidin expression. J. Biol. Chem. 284, 22580-22589 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 22580-22589
-
-
Zhang, A.S.1
Yang, F.2
Wang, J.3
Tsukamoto, H.4
Enns, C.A.5
-
15
-
-
84866742560
-
TGFβ signalling in context
-
Massagué, J. TGFβ signalling in context. Nat. Rev. Mol. Cell Biol. 13, 616-630 (2012).
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 616-630
-
-
Massagué, J.1
-
16
-
-
70649083092
-
Recent advances in BMP receptor signaling
-
Sieber, C., Kopf, J., Hiepen, C. & Knaus, P. Recent advances in BMP receptor signaling. Cytokine Growth Factor Rev. 20, 343-355 (2009).
-
(2009)
Cytokine Growth Factor Rev.
, vol.20
, pp. 343-355
-
-
Sieber, C.1
Kopf, J.2
Hiepen, C.3
Knaus, P.4
-
17
-
-
79151473137
-
Bone morphogenetic proteins: A critical review
-
Bragdon, B. et al. Bone morphogenetic proteins: a critical review. Cell. Signal. 23, 609-620 (2011).
-
(2011)
Cell. Signal.
, vol.23
, pp. 609-620
-
-
Bragdon, B.1
-
18
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi, Y. & Massagué, J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113, 685-700 (2003).
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massagué, J.2
-
19
-
-
23044466047
-
Specifcity and versatility in tgf-beta signaling through Smads
-
Feng, X.H. & Derynck, R. Specifcity and versatility in tgf-beta signaling through Smads. Annu. Rev. Cell Dev. Biol. 21, 659-693 (2005).
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 659-693
-
-
Feng, X.H.1
Derynck, R.2
-
20
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-β family signalling
-
Derynck, R. & Zhang, Y.E. Smad-dependent and Smad-independent pathways in TGF-β family signalling. Nature 425, 577-584 (2003).
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
21
-
-
0037598870
-
Distinct endocytic pathways regulate TGF-β receptor signalling and turnover
-
Di Guglielmo, G.M., Le Roy, C., Goodfellow, A.F. & Wrana, J.L. Distinct endocytic pathways regulate TGF-β receptor signalling and turnover. Nat. Cell Biol. 5, 410-421 (2003).
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 410-421
-
-
Di Guglielmo, G.M.1
Le Roy, C.2
Goodfellow, A.F.3
Wrana, J.L.4
-
22
-
-
33749586993
-
Different routes of bone morphogenic protein (BMP) receptor endocytosis infuence BMP signaling
-
Hartung, A. et al. Different routes of bone morphogenic protein (BMP) receptor endocytosis infuence BMP signaling. Mol. Cell. Biol. 26, 7791-7805 (2006).
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 7791-7805
-
-
Hartung, A.1
-
23
-
-
80053595685
-
Spatial segregation of BMP/Smad signaling affects osteoblast differentiation in C2C12 cells
-
Heining, E., Bhushan, R., Paarmann, P., Henis, Y.I. & Knaus, P. Spatial segregation of BMP/Smad signaling affects osteoblast differentiation in C2C12 cells. PLoS ONE 6, e25163 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. e25163
-
-
Heining, E.1
Bhushan, R.2
Paarmann, P.3
Henis, Y.I.4
Knaus, P.5
-
24
-
-
84875635566
-
Quantitative kinetics analysis of BMP2 uptake into cells and its modulation by BMP antagonists
-
Alborzinia, H. et al. Quantitative kinetics analysis of BMP2 uptake into cells and its modulation by BMP antagonists. J. Cell Sci. 126, 117-127 (2013).
-
(2013)
J. Cell Sci.
, vol.126
, pp. 117-127
-
-
Alborzinia, H.1
-
25
-
-
34248231196
-
Endofn acts as a Smad anchor for receptor activation in BMP signaling
-
Shi, W. et al. Endofn acts as a Smad anchor for receptor activation in BMP signaling. J. Cell Sci. 120, 1216-1224 (2007).
-
(2007)
J. Cell Sci.
, vol.120
, pp. 1216-1224
-
-
Shi, W.1
-
26
-
-
84928057976
-
BMP signalling: Agony and antagony in the family
-
Brazil, D.P., Church, R.H., Surae, S., Godson, C. & Martin, F. BMP signalling: agony and antagony in the family. Trends Cell Biol. 25, 249-264 (2015).
-
(2015)
Trends Cell Biol.
, vol.25
, pp. 249-264
-
-
Brazil, D.P.1
Church, R.H.2
Surae, S.3
Godson, C.4
Martin, F.5
-
27
-
-
79251564772
-
Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages
-
Xia, Y. et al. Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages. J. Immunol. 186, 1369-1376 (2011).
-
(2011)
J. Immunol.
, vol.186
, pp. 1369-1376
-
-
Xia, Y.1
-
28
-
-
2942619988
-
Genetic abnormalities and juvenile hemochromatosis: Mutations of the HJV gene encoding hemojuvelin
-
Lee, P.L., Beutler, E., Rao, S.V. & Barton, J.C. Genetic abnormalities and juvenile hemochromatosis: mutations of the HJV gene encoding hemojuvelin. Blood 103, 4669-4671 (2004).
-
(2004)
Blood
, vol.103
, pp. 4669-4671
-
-
Lee, P.L.1
Beutler, E.2
Rao, S.V.3
Barton, J.C.4
-
29
-
-
67651018727
-
Iron overload in the Asian community
-
Lok, C.Y. et al. Iron overload in the Asian community. Blood 114, 20-25 (2009).
-
(2009)
Blood
, vol.114
, pp. 20-25
-
-
Lok, C.Y.1
-
30
-
-
84904666636
-
Bone morphogenetic proteins as regulators of iron metabolism
-
Parrow, N.L. & Fleming, R.E. Bone morphogenetic proteins as regulators of iron metabolism. Annu. Rev. Nutr. 34, 77-94 (2014).
-
(2014)
Annu. Rev. Nutr.
, vol.34
, pp. 77-94
-
-
Parrow, N.L.1
Fleming, R.E.2
-
31
-
-
41849096388
-
Neogenin interacts with hemojuvelin through its two membrane-proximal fbronectin type III domains
-
Yang, F. , West, A.P. Jr., Allendorph, G.P., Choe, S. & Bjorkman, P.J. Neogenin interacts with hemojuvelin through its two membrane-proximal fbronectin type III domains. Biochemistry 47, 4237-4245 (2008).
-
(2008)
Biochemistry
, vol.47
, pp. 4237-4245
-
-
Yang, F.1
West, A.P.2
Allendorph, G.P.3
Choe, S.4
Bjorkman, P.J.5
-
32
-
-
84866928814
-
Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs)
-
Wu, Q., Sun, C.C., Lin, H.Y. & Babitt, J.L. Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs). PLoS ONE 7, e46307 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e46307
-
-
Wu, Q.1
Sun, C.C.2
Lin, H.Y.3
Babitt, J.L.4
-
33
-
-
0037023363
-
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand
-
Xiong, J.P. et al. Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science 296, 151-155 (2002).
-
(2002)
Science
, vol.296
, pp. 151-155
-
-
Xiong, J.P.1
-
34
-
-
34547687760
-
Molecular evolution of hemojuvelin and the repulsive guidance molecule family
-
Camus, L.M. & Lambert, L.A. Molecular evolution of hemojuvelin and the repulsive guidance molecule family. J. Mol. Evol. 65, 68-81 (2007).
-
(2007)
J. Mol. Evol.
, vol.65
, pp. 68-81
-
-
Camus, L.M.1
Lambert, L.A.2
-
35
-
-
41949115757
-
Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin
-
Kuns-Hashimoto, R., Kuninger, D., Nili, M. & Rotwein, P. Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin. Am. J. Physiol. Cell Physiol. 294, C994-C1003 (2008).
-
(2008)
Am. J. Physiol. Cell Physiol.
, vol.294
, pp. C994-C1003
-
-
Kuns-Hashimoto, R.1
Kuninger, D.2
Nili, M.3
Rotwein, P.4
-
36
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto, A. et al. Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat. Genet. 33, 21-22 (2003).
-
(2003)
Nat. Genet.
, vol.33
, pp. 21-22
-
-
Roetto, A.1
-
37
-
-
0037111732
-
Inappropriate expression of hepcidin is associated with iron refractory anemia: Implications for the anemia of chronic disease
-
Weinstein, D.A. et al. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood 100, 3776-3781 (2002).
-
(2002)
Blood
, vol.100
, pp. 3776-3781
-
-
Weinstein, D.A.1
-
38
-
-
54349097980
-
Hemojuvelin N-terminal mutants reach the plasma membrane but do not activate the hepcidin response
-
Pagani, A., Silvestri, L., Nai, A. & Camaschella, C. Hemojuvelin N-terminal mutants reach the plasma membrane but do not activate the hepcidin response. Haematologica 93, 1466-1472 (2008).
-
(2008)
Haematologica
, vol.93
, pp. 1466-1472
-
-
Pagani, A.1
Silvestri, L.2
Nai, A.3
Camaschella, C.4
-
39
-
-
33646749327
-
Structure of the ternary signaling complex of a TGF-beta superfamily member
-
Allendorph, G.P., Vale, W.W. & Choe, S. Structure of the ternary signaling complex of a TGF-beta superfamily member. Proc. Natl. Acad. Sci. USA 103, 7643-7648 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 7643-7648
-
-
Allendorph, G.P.1
Vale, W.W.2
Choe, S.3
-
40
-
-
33847118974
-
A silent H-bond can be mutationally activated for high-affnity interaction of BMP-2 and activin type IIB receptor
-
Weber, D. et al. A silent H-bond can be mutationally activated for high-affnity interaction of BMP-2 and activin type IIB receptor. BMC Struct. Biol. 7, 6 (2007).
-
(2007)
BMC Struct. Biol.
, vol.7
, pp. 6
-
-
Weber, D.1
-
41
-
-
84864990335
-
Specifcity and structure of a high affnity activin receptor-like kinase 1 (ALK1) signaling complex
-
Townson, S.A. et al. Specifcity and structure of a high affnity activin receptor-like kinase 1 (ALK1) signaling complex. J. Biol. Chem. 287, 27313-27325 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 27313-27325
-
-
Townson, S.A.1
-
42
-
-
70350037984
-
Receptor oligomerization and beyond: A case study in bone morphogenetic proteins
-
Heinecke, K. et al. Receptor oligomerization and beyond: a case study in bone morphogenetic proteins. BMC Biol. 7, 59 (2009).
-
(2009)
BMC Biol.
, vol.7
, pp. 59
-
-
Heinecke, K.1
-
43
-
-
2342516135
-
Molecular recognition of BMP-2 and BMP receptor IA
-
Keller, S., Nickel, J., Zhang, J.-L., Sebald, W. & Mueller, T.D. Molecular recognition of BMP-2 and BMP receptor IA. Nat. Struct. Mol. Biol. 11, 481-488 (2004).
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 481-488
-
-
Keller, S.1
Nickel, J.2
Zhang, J.-L.3
Sebald, W.4
Mueller, T.D.5
-
44
-
-
0037085441
-
Identifcation and functional characterization of distinct critically important bone morphogenetic protein-specifc response elements in the Id1 promoter
-
Korchynskyi, O. & ten Dijke, P. Identifcation and functional characterization of distinct critically important bone morphogenetic protein-specifc response elements in the Id1 promoter. J. Biol. Chem. 277, 4883-4891 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4883-4891
-
-
Korchynskyi, O.1
Ten Dijke, P.2
-
45
-
-
84871201282
-
Conformational states of the kinase Lck regulate clustering in early T cell signaling
-
Rossy, J., Owen, D.M., Williamson, D.J., Yang, Z. & Gaus, K. Conformational states of the kinase Lck regulate clustering in early T cell signaling. Nat. Immunol. 14, 82-89 (2013).
-
(2013)
Nat. Immunol.
, vol.14
, pp. 82-89
-
-
Rossy, J.1
Owen, D.M.2
Williamson, D.J.3
Yang, Z.4
Gaus, K.5
-
46
-
-
77954894949
-
Neogenin regulation of BMP-induced canonical Smad signaling and endochondral bone formation
-
Zhou, Z. et al. Neogenin regulation of BMP-induced canonical Smad signaling and endochondral bone formation. Dev. Cell 19, 90-102 (2010).
-
(2010)
Dev. Cell
, vol.19
, pp. 90-102
-
-
Zhou, Z.1
-
47
-
-
46749158788
-
Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin
-
Xia, Y., Babitt, J.L., Sidis, Y., Chung, R.T. & Lin, H.Y. Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. Blood 111, 5195-5204 (2008).
-
(2008)
Blood
, vol.111
, pp. 5195-5204
-
-
Xia, Y.1
Babitt, J.L.2
Sidis, Y.3
Chung, R.T.4
Lin, H.Y.5
-
48
-
-
84908356476
-
Modifying lipid rafts promotes regeneration and functional recovery
-
Tassew, N.G. et al. Modifying lipid rafts promotes regeneration and functional recovery. Cell Reports 8, 1146-1159 (2014).
-
(2014)
Cell Reports
, vol.8
, pp. 1146-1159
-
-
Tassew, N.G.1
-
49
-
-
0030461226
-
Control of EGF receptor signaling by clathrin-mediated endocytosis
-
Vieira, A.V., Lamaze, C. & Schmid, S.L. Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274, 2086-2089 (1996).
-
(1996)
Science
, vol.274
, pp. 2086-2089
-
-
Vieira, A.V.1
Lamaze, C.2
Schmid, S.L.3
-
50
-
-
13444263549
-
Clathrin-and non-clathrin-mediated endocytic regulation of cell signalling
-
Le Roy, C. & Wrana, J.L. Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling. Nat. Rev. Mol. Cell Biol. 6, 112-126 (2005).
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 112-126
-
-
Le Roy, C.1
Wrana, J.L.2
-
51
-
-
84879793105
-
Structure of the repulsive guidance molecule (RGM)-neogenin signaling hub
-
Bell, C.H. et al. Structure of the repulsive guidance molecule (RGM)-neogenin signaling hub. Science 341, 77-80 (2013).
-
(2013)
Science
, vol.341
, pp. 77-80
-
-
Bell, C.H.1
-
52
-
-
33745912405
-
A time- and cost-effcient system for high-level protein production in mammalian cells
-
Aricescu, A.R., Lu, W. & Jones, E.Y. A time- and cost-effcient system for high-level protein production in mammalian cells. Acta Crystallogr. D Biol. Crystallogr. 62, 1243-1250 (2006).
-
(2006)
Acta Crystallogr. D Biol. Crystallogr.
, vol.62
, pp. 1243-1250
-
-
Aricescu, A.R.1
Lu, W.2
Jones, E.Y.3
-
53
-
-
79959935033
-
Automation of large scale transient protein expression in mammalian cells
-
Zhao, Y. et al. Automation of large scale transient protein expression in mammalian cells. J. Struct. Biol. 175, 209-215 (2011).
-
(2011)
J. Struct. Biol.
, vol.175
, pp. 209-215
-
-
Zhao, Y.1
-
54
-
-
33847653747
-
Glycoprotein structural genomics: Solving the glycosylation problem
-
Chang, V.T. et al. Glycoprotein structural genomics: solving the glycosylation problem. Structure 15, 267-273 (2007).
-
(2007)
Structure
, vol.15
, pp. 267-273
-
-
Chang, V.T.1
-
55
-
-
77955429857
-
A novel TWO-STEP renaturation procedure for effcient production of recombinant BMP-2
-
von Einem, S., Schwarz, E. & Rudolph, R. A novel TWO-STEP renaturation procedure for effcient production of recombinant BMP-2. Protein Expr. Purif. 73, 65-69 (2010).
-
(2010)
Protein Expr. Purif.
, vol.73
, pp. 65-69
-
-
Von Einem, S.1
Schwarz, E.2
Rudolph, R.3
-
56
-
-
0344393021
-
Quality control and protein folding in the secretory pathway
-
Trombetta, E.S. & Parodi, A.J. Quality control and protein folding in the secretory pathway. Annu. Rev. Cell Dev. Biol. 19, 649-676 (2003).
-
(2003)
Annu. Rev. Cell Dev. Biol.
, vol.19
, pp. 649-676
-
-
Trombetta, E.S.1
Parodi, A.J.2
-
57
-
-
23844515485
-
A procedure for setting up high-throughput nanolitre crystallization experiments: Crystallization workfow for initial screening, automated storage, imaging and optimization
-
Walter, T.S. et al. A procedure for setting up high-throughput nanolitre crystallization experiments: crystallization workfow for initial screening, automated storage, imaging and optimization. Acta Crystallogr. D Biol. Crystallogr. 61, 651-657 (2005).
-
(2005)
Acta Crystallogr. D Biol. Crystallogr.
, vol.61
, pp. 651-657
-
-
Walter, T.S.1
-
58
-
-
13844266400
-
Benefts of automated crystallization plate tracking, imaging, and analysis
-
Mayo, C.J. et al. Benefts of automated crystallization plate tracking, imaging, and analysis. Structure 13, 175-182 (2005).
-
(2005)
Structure
, vol.13
, pp. 175-182
-
-
Mayo, C.J.1
-
59
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307-326 (1997).
-
(1997)
Methods Enzymol.
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
61
-
-
85027632383
-
Automatic indexing of rotation diffraction patterns
-
Kabsch, W. Automatic indexing of rotation diffraction patterns. J. Appl. Crystallogr. 21, 67-72 (1988).
-
(1988)
J. Appl. Crystallogr.
, vol.21
, pp. 67-72
-
-
Kabsch, W.1
-
62
-
-
0027879008
-
Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants
-
Kabsch, W. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants. J. Appl. Crystallogr. 26, 795-800 (1993).
-
(1993)
J. Appl. Crystallogr.
, vol.26
, pp. 795-800
-
-
Kabsch, W.1
-
63
-
-
33644874235
-
The integration of macromolecular diffraction data
-
Leslie, A.G.W. The integration of macromolecular diffraction data. Acta Crystallogr. D Biol. Crystallogr. 62, 48-57 (2006).
-
(2006)
Acta Crystallogr. D Biol. Crystallogr.
, vol.62
, pp. 48-57
-
-
Leslie, A.G.W.1
-
64
-
-
3442885393
-
Robust indexing for automatic data collection
-
Sauter, N.K., Grosse-Kunstleve, R.W. & Adams, P.D. Robust indexing for automatic data collection. J. Appl. Crystallogr. 37, 399-409 (2004).
-
(2004)
J. Appl. Crystallogr.
, vol.37
, pp. 399-409
-
-
Sauter, N.K.1
Grosse-Kunstleve, R.W.2
Adams, P.D.3
-
65
-
-
33645160257
-
Automated diffraction image analysis and spot searching for high-throughput crystal screening
-
Zhang, Z., Sauter, N.K., van den Bedem, H., Snell, G. & Deacon, A.M. Automated diffraction image analysis and spot searching for high-throughput crystal screening. J. Appl. Crystallogr. 39, 112-119 (2006).
-
(2006)
J. Appl. Crystallogr.
, vol.39
, pp. 112-119
-
-
Zhang, Z.1
Sauter, N.K.2
Van Den Bedem, H.3
Snell, G.4
Deacon, A.M.5
-
66
-
-
34447508216
-
Phaser crystallographic software
-
McCoy, A.J. et al. Phaser crystallographic software. J. Appl. Crystallogr. 40, 658-674 (2007).
-
(2007)
J. Appl. Crystallogr.
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
-
67
-
-
0033582942
-
Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution
-
Scheufer, C., Sebald, W. & Hulsmeyer, M. Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution. J. Mol. Biol. 287, 103-115 (1999).
-
(1999)
J. Mol. Biol.
, vol.287
, pp. 103-115
-
-
Scheufer, C.1
Sebald, W.2
Hulsmeyer, M.3
-
68
-
-
77950798648
-
Recent developments in classical density modifcation
-
Cowtan, K. Recent developments in classical density modifcation. Acta Crystallogr. D Biol. Crystallogr. 66, 470-478 (2010).
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 470-478
-
-
Cowtan, K.1
-
69
-
-
33748337934
-
The Buccaneer software for automated model building. 1. Tracing protein chains
-
Cowtan, K. The Buccaneer software for automated model building. 1. Tracing protein chains. Acta Crystallogr. D Biol. Crystallogr. 62, 1002-1011 (2006).
-
(2006)
Acta Crystallogr. D Biol. Crystallogr.
, vol.62
, pp. 1002-1011
-
-
Cowtan, K.1
-
71
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
Adams, P.D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D Biol. Crystallogr. 66, 213-221 (2010).
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
-
72
-
-
34547592557
-
MolProbity: All-atom contacts and structure validation for proteins and nucleic acids
-
Davis, I.W. et al. MolProbity: all-atom contacts and structure validation for proteins and nucleic acids. Nucleic Acids Res. 35, W375-W383 (2007).
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. W375-W383
-
-
Davis, I.W.1
-
73
-
-
0035964342
-
Electrostatics of nanosystems: Application to microtubules and the ribosome
-
Baker, N.A., Sept, D., Joseph, S., Holst, M.J. & McCammon, J.A. Electrostatics of nanosystems: application to microtubules and the ribosome. Proc. Natl. Acad. Sci. USA 98, 10037-10041 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10037-10041
-
-
Baker, N.A.1
Sept, D.2
Joseph, S.3
Holst, M.J.4
McCammon, J.A.5
-
74
-
-
34548232365
-
Inference of macromolecular assemblies from crystalline state
-
Krissinel, E. & Henrick, K. Inference of macromolecular assemblies from crystalline state. J. Mol. Biol. 372, 774-797 (2007).
-
(2007)
J. Mol. Biol.
, vol.372
, pp. 774-797
-
-
Krissinel, E.1
Henrick, K.2
-
75
-
-
84879169814
-
Upgraded ESRF BM29 beamline for SAXS on macromolecules in solution
-
Pernot, P. et al. Upgraded ESRF BM29 beamline for SAXS on macromolecules in solution. J. Synchrotron Radiat. 20, 660-664 (2013).
-
(2013)
J. Synchrotron Radiat.
, vol.20
, pp. 660-664
-
-
Pernot, P.1
-
76
-
-
84859782518
-
New developments in the ATSAS program package for small-angle scattering data analysis
-
Petoukhov, M.V. et al. New developments in the ATSAS program package for small-angle scattering data analysis. J. Appl. Crystallogr. 45, 342-350 (2012).
-
(2012)
J. Appl. Crystallogr.
, vol.45
, pp. 342-350
-
-
Petoukhov, M.V.1
-
77
-
-
84876800465
-
Accurate assessment of mass, models and resolution by small-angle scattering
-
Rambo, R.P. & Tainer, J.A. Accurate assessment of mass, models and resolution by small-angle scattering. Nature 496, 477-481 (2013).
-
(2013)
Nature
, vol.496
, pp. 477-481
-
-
Rambo, R.P.1
Tainer, J.A.2
-
78
-
-
78650905964
-
ROSETTA3: An object-oriented software suite for the simulation and design of macromolecules
-
Leaver-Fay, A. et al. ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules. Methods Enzymol. 487, 545-574 (2011).
-
(2011)
Methods Enzymol.
, vol.487
, pp. 545-574
-
-
Leaver-Fay, A.1
-
79
-
-
0043123167
-
Tools for comparative protein structure modeling and analysis
-
Eswar, N. et al. Tools for comparative protein structure modeling and analysis. Nucleic Acids Res. 31, 3375-3380 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3375-3380
-
-
Eswar, N.1
-
80
-
-
84859455527
-
Structure-based model of allostery predicts coupling between distant sites
-
Weinkam, P. , Pons, J. & Sali, A. Structure-based model of allostery predicts coupling between distant sites. Proc. Natl. Acad. Sci. USA 109, 4875-4880 (2012).
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 4875-4880
-
-
Weinkam, P.1
Pons, J.2
Sali, A.3
-
81
-
-
67650992092
-
Structure and fexibility within proteins as identifed through small angle X-ray scattering
-
Pelikan, M., Hura, G.L. & Hammel, M. Structure and fexibility within proteins as identifed through small angle X-ray scattering. Gen. Physiol. Biophys. 28, 174-189 (2009).
-
(2009)
Gen. Physiol. Biophys.
, vol.28
, pp. 174-189
-
-
Pelikan, M.1
Hura, G.L.2
Hammel, M.3
-
82
-
-
84882940564
-
Accurate SAXS profle computation and its assessment by contrast variation experiments
-
Schneidman-Duhovny, D., Hammel, M., Tainer, J.A. & Sali, A. Accurate SAXS profle computation and its assessment by contrast variation experiments. Biophys. J. 105, 962-974 (2013).
-
(2013)
Biophys. J.
, vol.105
, pp. 962-974
-
-
Schneidman-Duhovny, D.1
Hammel, M.2
Tainer, J.A.3
Sali, A.4
-
83
-
-
84874855471
-
All-atom ensemble modeling to analyze small-angle x-ray scattering of glycosylated proteins
-
Guttman, M., Weinkam, P., Sali, A. & Lee, K.K. All-atom ensemble modeling to analyze small-angle x-ray scattering of glycosylated proteins. Structure 21, 321-331 (2013).
-
(2013)
Structure
, vol.21
, pp. 321-331
-
-
Guttman, M.1
Weinkam, P.2
Sali, A.3
Lee, K.K.4
-
84
-
-
0025944815
-
Immobilization of proteins to a carboxymethyldextran-modifed gold surface for biospecifc interaction analysis in surface plasmon resonance sensors
-
Johnsson, B., Löfås, S. & Lindquist, G. Immobilization of proteins to a carboxymethyldextran-modifed gold surface for biospecifc interaction analysis in surface plasmon resonance sensors. Anal. Biochem. 198, 268-277 (1991).
-
(1991)
Anal. Biochem.
, vol.198
, pp. 268-277
-
-
Johnsson, B.1
Löfås, S.2
Lindquist, G.3
-
85
-
-
64049114344
-
A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins: Identifcation and quantifcation of BMP4 BMP6 and BMP9 in bovine and human serum
-
Herrera, B. & Inman, G.J. A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins: identifcation and quantifcation of BMP4, BMP6 and BMP9 in bovine and human serum. BMC Cell Biol. 10, 20 (2009).
-
(2009)
BMC Cell Biol.
, vol.10
, pp. 20
-
-
Herrera, B.1
Inman, G.J.2
-
86
-
-
0037085441
-
Identifcation and functional characterization of distinct critically important bone morphogenetic protein-specifc response elements in the Id1 promoter
-
Korchynskyi, O. & ten Dijke, P. Identifcation and functional characterization of distinct critically important bone morphogenetic protein-specifc response elements in the Id1 promoter. J. Biol. Chem. 277, 4883-4891 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4883-4891
-
-
Korchynskyi, O.1
Ten Dijke, P.2
-
87
-
-
1642300769
-
SpPack: Spatial point pattern analysis in Excel using Visual Basic for Applications (VBA)
-
Perry, G.L.W. SpPack: spatial point pattern analysis in Excel using Visual Basic for Applications (VBA). Environ. Model. Softw. 19, 559-569 (2004).
-
(2004)
Environ. Model. Softw.
, vol.19
, pp. 559-569
-
-
Perry, G.L.W.1
-
88
-
-
84871201282
-
Conformational states of the kinase Lck regulate clustering in early T cell signaling
-
Rossy, J., Owen, D.M., Williamson, D.J., Yang, Z. & Gaus, K. Conformational states of the kinase Lck regulate clustering in early T cell signaling. Nat. Immunol. 14, 82-89 (2013).
-
(2013)
Nat. Immunol.
, vol.14
, pp. 82-89
-
-
Rossy, J.1
Owen, D.M.2
Williamson, D.J.3
Yang, Z.4
Gaus, K.5
-
89
-
-
77954630046
-
PALM imaging and cluster analysis of protein heterogeneity at the cell surface
-
Owen, D.M. et al. PALM imaging and cluster analysis of protein heterogeneity at the cell surface. J Biophotonics 3, 446-454 (2010).
-
(2010)
J Biophotonics
, vol.3
, pp. 446-454
-
-
Owen, D.M.1
-
90
-
-
84855965214
-
Optical techniques for imaging membrane domains in live cells (live-cell palm of protein clustering)
-
Owen, D.M., Williamson, D., Magenau, A. & Gaus, K. Optical techniques for imaging membrane domains in live cells (live-cell palm of protein clustering). Methods Enzymol. 504, 221-235 (2012).
-
(2012)
Methods Enzymol.
, vol.504
, pp. 221-235
-
-
Owen, D.M.1
Williamson, D.2
Magenau, A.3
Gaus, K.4
-
91
-
-
79959373064
-
Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events
-
Williamson, D.J. et al. Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events. Nat. Immunol. 12, 655-662 (2011).
-
(2011)
Nat. Immunol.
, vol.12
, pp. 655-662
-
-
Williamson, D.J.1
|