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Volumn 126, Issue 1, 2013, Pages 117-127

Quantitative kinetics analysis of BMP2 uptake into cells and its modulation by BMP antagonists

Author keywords

BMP antagonists; BMP signaling; Endocytosis; Fluorescently labeled BMP2

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN ANTAGONIST; CHORDIN; CLATHRIN; GREMLIN; NOGGIN; PROTEIN INHIBITOR; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

EID: 84875635566     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.109777     Document Type: Article
Times cited : (32)

References (34)
  • 1
    • 0033573098 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of caveolin-1 in the endothelium
    • Aoki, T., Nomura, R. and Fujimoto, T. (1999). Tyrosine phosphorylation of caveolin-1 in the endothelium. Exp. Cell Res. 253, 629-636.
    • (1999) Exp. Cell Res. , vol.253 , pp. 629-636
    • Aoki, T.1    Nomura, R.2    Fujimoto, T.3
  • 2
    • 0347916881 scopus 로고    scopus 로고
    • Comparative genomic analysis of the eight-membered ring cystine knot-containing bone morphogenetic protein antagonists
    • Avsian-Kretchmer, O. and Hsueh, A. J. (2004). Comparative genomic analysis of the eight-membered ring cystine knot-containing bone morphogenetic protein antagonists. Mol. Endocrinol. 18, 1-12.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 1-12
    • Avsian-Kretchmer, O.1    Hsueh, A.J.2
  • 3
    • 58149269185 scopus 로고    scopus 로고
    • Endocytic regulation of TGF-beta signaling
    • Chen, Y. G. (2009). Endocytic regulation of TGF-beta signaling. Cell Res. 19, 58-70.
    • (2009) Cell Res. , vol.19 , pp. 58-70
    • Chen, Y.G.1
  • 4
    • 12344291865 scopus 로고    scopus 로고
    • Bone morphogenetic proteins
    • Chen, D., Zhao, M. and Mundy, G. R. (2004). Bone morphogenetic proteins. Growth Factors 22, 233-241.
    • (2004) Growth Factors , vol.22 , pp. 233-241
    • Chen, D.1    Zhao, M.2    Mundy, G.R.3
  • 6
    • 78649408374 scopus 로고    scopus 로고
    • Smad7 dependent gene expression signature highlights crosstalk of TGF-b and BMP2 pathways and the importance of sugar metabolism in HSC transdifferentiation
    • Denecke, B., Wickert, L., Liu, Y., Ciuclan, L., Dooley, S. and Meindl-Beinker, N. M. (2010). Smad7 dependent gene expression signature highlights crosstalk of TGF-b and BMP2 pathways and the importance of sugar metabolism in HSC transdifferentiation. World J. Gastroenterol. 16, 5211-5224.
    • (2010) World J. Gastroenterol. , vol.16 , pp. 5211-5224
    • Denecke, B.1    Wickert, L.2    Liu, Y.3    Ciuclan, L.4    Dooley, S.5    Meindl-Beinker, N.M.6
  • 7
    • 0037598870 scopus 로고    scopus 로고
    • Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover
    • Di Guglielmo, G. M., Le Roy, C., Goodfellow, A. F. and Wrana, J. L. (2003). Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover. Nat. Cell Biol. 5, 410-421.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 410-421
    • Di Guglielmo, G.M.1    Le Roy, C.2    Goodfellow, A.F.3    Wrana, J.L.4
  • 11
    • 58149264873 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling of Smad proteins
    • Hill, C. S. (2009). Nucleocytoplasmic shuttling of Smad proteins. Cell Res. 19, 36-46.
    • (2009) Cell Res. , vol.19 , pp. 36-46
    • Hill, C.S.1
  • 12
    • 33847717517 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells
    • Jiao, X., Billings, P. C., O'Connell, M. P., Kaplan, F. S., Shore, E. M. and Glaser, D. L. (2007). Heparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells. J. Biol. Chem. 282, 1080-1086.
    • (2007) J. Biol. Chem. , vol.282 , pp. 1080-1086
    • Jiao, X.1    Billings, P.C.2    O'Connell, M.P.3    Kaplan, F.S.4    Shore, E.M.5    Glaser, D.L.6
  • 13
    • 61449116935 scopus 로고    scopus 로고
    • A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling
    • Kelley, R., Ren, R., Pi, X., Wu, Y., Moreno, I., Willis, M., Moser, M., Ross, M., Podkowa, M., Attisano, L. et al. (2009). A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling. J. Cell Biol. 184, 597-609.
    • (2009) J. Cell Biol. , vol.184 , pp. 597-609
    • Kelley, R.1    Ren, R.2    Pi, X.3    Wu, Y.4    Moreno, I.5    Willis, M.6    Moser, M.7    Ross, M.8    Podkowa, M.9    Attisano, L.10
  • 14
    • 0037085441 scopus 로고    scopus 로고
    • Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
    • Korchynskyi, O. and ten Dijke, P. (2002). Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J. Biol. Chem. 277, 4883-4891.
    • (2002) J. Biol. Chem. , vol.277 , pp. 4883-4891
    • Korchynskyi, O.1    Ten Dijke, P.2
  • 15
    • 78649672230 scopus 로고    scopus 로고
    • Heparan sulfate acts as a bone morphogenetic protein coreceptor by facilitating ligand-induced receptor heterooligomerization
    • Kuo, W. J., Digman, M. A. and Lander, A. D. (2010). Heparan sulfate acts as a bone morphogenetic protein coreceptor by facilitating ligand-induced receptor heterooligomerization. Mol. Biol. Cell 21, 4028-4041.
    • (2010) Mol. Biol. Cell , vol.21 , pp. 4028-4041
    • Kuo, W.J.1    Digman, M.A.2    Lander, A.D.3
  • 16
    • 79951804968 scopus 로고    scopus 로고
    • Icariin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro
    • Ma, H. P., Ming, L. G., Ge, B. F., Zhai, Y. K., Song, P., Xian, C. J. and Chen, K. M. (2011). Icariin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro. J. Cell. Biochem. 112, 916-923.
    • (2011) J. Cell. Biochem. , vol.112 , pp. 916-923
    • Ma, H.P.1    Ming, L.G.2    Ge, B.F.3    Zhai, Y.K.4    Song, P.5    Xian, C.J.6    Chen, K.M.7
  • 17
    • 0033402727 scopus 로고    scopus 로고
    • The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb
    • Merino, R., Rodriguez-Leon, J., Macias, D., Gañan, Y., Economides, A. N. and Hurle, J. M. (1999). The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb. Development 126, 5515-5522.
    • (1999) Development , vol.126 , pp. 5515-5522
    • Merino, R.1    Rodriguez-Leon, J.2    Macias, D.3    Gañan, Y.4    Economides, A.N.5    Hurle, J.M.6
  • 19
    • 0025240867 scopus 로고
    • Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity
    • Mollenhauer, H. H., Morré, D. J. and Rowe, L. D. (1990). Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity. Biochim. Biophys. Acta 1031, 225-246.
    • (1990) Biochim. Biophys. Acta , vol.1031 , pp. 225-246
    • Mollenhauer, H.H.1    Morré, D.J.2    Rowe, L.D.3
  • 20
    • 84855440185 scopus 로고    scopus 로고
    • Surface immobilization of bone morphogenetic protein 2 via a self-assembled monolayer formation induces cell differentiation
    • Pohl, T. L., Boergermann, J. H., Schwaerzer, G. K., Knaus, P. and Cavalcanti-Adam, E. A. (2012). Surface immobilization of bone morphogenetic protein 2 via a self-assembled monolayer formation induces cell differentiation. Acta Biomater. 8, 772-780.
    • (2012) Acta Biomater. , vol.8 , pp. 772-780
    • Pohl, T.L.1    Boergermann, J.H.2    Schwaerzer, G.K.3    Knaus, P.4    Cavalcanti-Adam, E.A.5
  • 23
    • 0027967380 scopus 로고
    • Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes
    • Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K. and De Robertis, E. M. (1994). Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790.
    • (1994) Cell , vol.79 , pp. 779-790
    • Sasai, Y.1    Lu, B.2    Steinbeisser, H.3    Geissert, D.4    Gont, L.K.5    De Robertis, E.M.6
  • 24
    • 67650514349 scopus 로고    scopus 로고
    • Systems biological analysis of epidermal growth factor receptor internalization dynamics for altered receptor levels
    • Schmidt-Glenewinkel, H., Reinz, E., Eils, R. and Brady, N. R. (2009). Systems biological analysis of epidermal growth factor receptor internalization dynamics for altered receptor levels. J. Biol. Chem. 284, 17243-17252.
    • (2009) J. Biol. Chem. , vol.284 , pp. 17243-17252
    • Schmidt-Glenewinkel, H.1    Reinz, E.2    Eils, R.3    Brady, N.R.4
  • 25
    • 36448936383 scopus 로고    scopus 로고
    • TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility
    • Schmierer, B. and Hill, C. S. (2007). TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat. Rev. Mol. Cell Biol. 8, 970-982.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 970-982
    • Schmierer, B.1    Hill, C.S.2
  • 26
    • 0037672212 scopus 로고    scopus 로고
    • Functional differentiation of hepatocyte-like spheroid structures from putative liver progenitor cells in three-dimensional peptide scaffolds
    • Semino, C. E., Merok, J. R., Crane, G. G., Panagiotakos, G. and Zhang, S. (2003). Functional differentiation of hepatocyte-like spheroid structures from putative liver progenitor cells in three-dimensional peptide scaffolds. Differentiation 71, 262-270.
    • (2003) Differentiation , vol.71 , pp. 262-270
    • Semino, C.E.1    Merok, J.R.2    Crane, G.G.3    Panagiotakos, G.4    Zhang, S.5
  • 30
    • 70450170394 scopus 로고    scopus 로고
    • The extracellular regulation of bone morphogenetic protein signaling
    • Umulis, D., O'Connor, M. B. and Blair, S. S. (2009). The extracellular regulation of bone morphogenetic protein signaling. Development 136, 3715-3728.
    • (2009) Development , vol.136 , pp. 3715-3728
    • Umulis, D.1    O'Connor, M.B.2    Blair, S.S.3
  • 31
    • 79955850865 scopus 로고    scopus 로고
    • The pro-form of BMP-2 exhibits a delayed and reduced activity when compared to mature BMP-2
    • von Einem, S., Erler, S., Bigl, K., Frerich, B. and Schwarz, E. (2011). The pro-form of BMP-2 exhibits a delayed and reduced activity when compared to mature BMP-2. Growth Factors 29, 63-71.
    • (2011) Growth Factors , vol.29 , pp. 63-71
    • von Einem, S.1    Erler, S.2    Bigl, K.3    Frerich, B.4    Schwarz, E.5
  • 32
    • 77952548279 scopus 로고    scopus 로고
    • Extracellular BMPantagonist regulation in development and disease: tied up in knots
    • Walsh, D. W., Godson, C., Brazil, D. P. and Martin, F. (2010). Extracellular BMPantagonist regulation in development and disease: tied up in knots. Trends Cell Biol. 20, 244-256.
    • (2010) Trends Cell Biol. , vol.20 , pp. 244-256
    • Walsh, D.W.1    Godson, C.2    Brazil, D.P.3    Martin, F.4
  • 34
    • 34547117636 scopus 로고    scopus 로고
    • von Willebrand factor type C domain-containing proteins regulate bone morphogenetic protein signaling through different recognition mechanisms
    • Zhang, J. L., Huang, Y., Qiu, L. Y., Nickel, J. and Sebald, W. (2007). von Willebrand factor type C domain-containing proteins regulate bone morphogenetic protein signaling through different recognition mechanisms. J. Biol. Chem. 282, 20002-20014.
    • (2007) J. Biol. Chem. , vol.282 , pp. 20002-20014
    • Zhang, J.L.1    Huang, Y.2    Qiu, L.Y.3    Nickel, J.4    Sebald, W.5


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