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Volumn 7, Issue 9, 2012, Pages

Repulsive Guidance Molecule (RGM) Family Proteins Exhibit Differential Binding Kinetics for Bone Morphogenetic Proteins (BMPs)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 5; BONE MORPHOGENETIC PROTEIN 6; HEMOJUVELIN; LIGAND; OSTEOGENIC PROTEIN 1; PROTEIN RGMA; PROTEIN RGMB; RECEPTOR PROTEIN; REPULSIVE GUIDANCE MOLECULE PROTEIN; UNCLASSIFIED DRUG;

EID: 84866928814     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046307     Document Type: Article
Times cited : (46)

References (52)
  • 1
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y, Massague J, (2003) Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 4
    • 23844456919 scopus 로고    scopus 로고
    • Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor
    • Babitt JL, Zhang Y, Samad TA, Xia Y, Tang J, et al. (2005) Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor. J Biol Chem 280: 29820-29827.
    • (2005) J Biol Chem , vol.280 , pp. 29820-29827
    • Babitt, J.L.1    Zhang, Y.2    Samad, T.A.3    Xia, Y.4    Tang, J.5
  • 5
    • 33646370235 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
    • Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, et al. (2006) Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet 38: 531-539.
    • (2006) Nat Genet , vol.38 , pp. 531-539
    • Babitt, J.L.1    Huang, F.W.2    Wrighting, D.M.3    Xia, Y.4    Sidis, Y.5
  • 7
  • 8
    • 10744228029 scopus 로고    scopus 로고
    • DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties
    • Samad TA, Srinivasan A, Karchewski LA, Jeong SJ, Campagna JA, et al. (2004) DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci 24: 2027-2036.
    • (2004) J Neurosci , vol.24 , pp. 2027-2036
    • Samad, T.A.1    Srinivasan, A.2    Karchewski, L.A.3    Jeong, S.J.4    Campagna, J.A.5
  • 9
    • 0742322861 scopus 로고    scopus 로고
    • Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system
    • Niederkofler V, Salie R, Sigrist M, Arber S, (2004) Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci 24: 808-818.
    • (2004) J Neurosci , vol.24 , pp. 808-818
    • Niederkofler, V.1    Salie, R.2    Sigrist, M.3    Arber, S.4
  • 10
    • 0344234409 scopus 로고    scopus 로고
    • Isolation and expression pattern of three mouse homologues of chick Rgm
    • Schmidtmer J, Engelkamp D, (2004) Isolation and expression pattern of three mouse homologues of chick Rgm. Gene Expr Patterns 4: 105-110.
    • (2004) Gene Expr Patterns , vol.4 , pp. 105-110
    • Schmidtmer, J.1    Engelkamp, D.2
  • 11
    • 1642395635 scopus 로고    scopus 로고
    • Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development
    • Oldekamp J, Kramer N, Alvarez-Bolado G, Skutella T, (2004) Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development. Gene Expr Patterns 4: 283-288.
    • (2004) Gene Expr Patterns , vol.4 , pp. 283-288
    • Oldekamp, J.1    Kramer, N.2    Alvarez-Bolado, G.3    Skutella, T.4
  • 12
    • 27144459908 scopus 로고    scopus 로고
    • Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin
    • Lin L, Goldberg YP, Ganz T, (2005) Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin. Blood 106: 2884-2889.
    • (2005) Blood , vol.106 , pp. 2884-2889
    • Lin, L.1    Goldberg, Y.P.2    Ganz, T.3
  • 13
    • 42249103992 scopus 로고    scopus 로고
    • Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin
    • Kuninger D, Kuns-Hashimoto R, Nili M, Rotwein P, (2008) Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin. BMC Biochem 9: 9.
    • (2008) BMC Biochem , vol.9 , pp. 9
    • Kuninger, D.1    Kuns-Hashimoto, R.2    Nili, M.3    Rotwein, P.4
  • 14
    • 38349194098 scopus 로고    scopus 로고
    • Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis
    • Silvestri L, Pagani A, Camaschella C, (2008) Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis. Blood 111: 924-931.
    • (2008) Blood , vol.111 , pp. 924-931
    • Silvestri, L.1    Pagani, A.2    Camaschella, C.3
  • 15
    • 36649027658 scopus 로고    scopus 로고
    • Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site
    • Lin L, Nemeth E, Goodnough JB, Thapa DR, Gabayan V, et al. (2011) Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site. Blood Cells Mol Dis 40: 122-131.
    • (2011) Blood Cells Mol Dis , vol.40 , pp. 122-131
    • Lin, L.1    Nemeth, E.2    Goodnough, J.B.3    Thapa, D.R.4    Gabayan, V.5
  • 16
    • 56449096622 scopus 로고    scopus 로고
    • The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin
    • Silvestri L, Pagani A, Nai A, De Domenico I, Kaplan J, et al. (2008) The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin. Cell Metab 8: 502-511.
    • (2008) Cell Metab , vol.8 , pp. 502-511
    • Silvestri, L.1    Pagani, A.2    Nai, A.3    de Domenico, I.4    Kaplan, J.5
  • 17
    • 84857014510 scopus 로고    scopus 로고
    • SKI-1 and Furin generate multiple RGMa fragments that regulate axonal growth
    • Tassew NG, Charish J, Seidah NG, Monnier PP, (2012) SKI-1 and Furin generate multiple RGMa fragments that regulate axonal growth. Dev Cell 22: 391-402.
    • (2012) Dev Cell , vol.22 , pp. 391-402
    • Tassew, N.G.1    Charish, J.2    Seidah, N.G.3    Monnier, P.P.4
  • 18
    • 63449103712 scopus 로고    scopus 로고
    • BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
    • Andriopoulos B Jr, Corradini E, Xia Y, Faasse SA, Chen S, et al. (2009) BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet 41: 482-487.
    • (2009) Nat Genet , vol.41 , pp. 482-487
    • Andriopoulos Jr., B.1    Corradini, E.2    Xia, Y.3    Faasse, S.A.4    Chen, S.5
  • 19
    • 34447137331 scopus 로고    scopus 로고
    • Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance
    • Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, et al. (2007) Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. J Clin Invest 117: 1933-1939.
    • (2007) J Clin Invest , vol.117 , pp. 1933-1939
    • Babitt, J.L.1    Huang, F.W.2    Xia, Y.3    Sidis, Y.4    Andrews, N.C.5
  • 20
    • 23644444316 scopus 로고    scopus 로고
    • Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
    • Niederkofler V, Salie R, Arber S, (2005) Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload. J Clin Invest 115: 2180-2186.
    • (2005) J Clin Invest , vol.115 , pp. 2180-2186
    • Niederkofler, V.1    Salie, R.2    Arber, S.3
  • 22
    • 11144358032 scopus 로고    scopus 로고
    • The repulsive guidance molecule RGMa is involved in the formation of afferent connections in the dentate gyrus
    • Brinks H, Conrad S, Vogt J, Oldekamp J, Sierra A, et al. (2004) The repulsive guidance molecule RGMa is involved in the formation of afferent connections in the dentate gyrus. J Neurosci 24: 3862-3869.
    • (2004) J Neurosci , vol.24 , pp. 3862-3869
    • Brinks, H.1    Conrad, S.2    Vogt, J.3    Oldekamp, J.4    Sierra, A.5
  • 25
    • 33645740851 scopus 로고    scopus 로고
    • RGMa inhibition promotes axonal growth and recovery after spinal cord injury
    • Hata K, Fujitani M, Yasuda Y, Doya H, Saito T, et al. (2006) RGMa inhibition promotes axonal growth and recovery after spinal cord injury. J Cell Biol 173: 47-58.
    • (2006) J Cell Biol , vol.173 , pp. 47-58
    • Hata, K.1    Fujitani, M.2    Yasuda, Y.3    Doya, H.4    Saito, T.5
  • 26
    • 33745264438 scopus 로고    scopus 로고
    • Repulsive guidance molecule plays multiple roles in neuronal differentiation and axon guidance
    • Matsunaga E, Nakamura H, Chédotal A, (2006) Repulsive guidance molecule plays multiple roles in neuronal differentiation and axon guidance. J Neurosci 26: 6082-6088.
    • (2006) J Neurosci , vol.26 , pp. 6082-6088
    • Matsunaga, E.1    Nakamura, H.2    Chédotal, A.3
  • 27
    • 33746875636 scopus 로고    scopus 로고
    • Neogenin interacts with RGMa and netrin-1 to guide axons within the embryonic vertebrate forebrain
    • Wilson NH, Key B, (2006) Neogenin interacts with RGMa and netrin-1 to guide axons within the embryonic vertebrate forebrain. Dev Biol 296: 485-498.
    • (2006) Dev Biol , vol.296 , pp. 485-498
    • Wilson, N.H.1    Key, B.2
  • 28
    • 58149383267 scopus 로고    scopus 로고
    • Neogenin and RGMa control neural tube closure and neuroepithelial morphology by regulating cell polarity
    • Kee N, Wilson N, De Vries M, Bradford D, Key B, et al. (2008) Neogenin and RGMa control neural tube closure and neuroepithelial morphology by regulating cell polarity. J Neurosci 28: 12643-12653.
    • (2008) J Neurosci , vol.28 , pp. 12643-12653
    • Kee, N.1    Wilson, N.2    de Vries, M.3    Bradford, D.4    Key, B.5
  • 29
    • 77953808895 scopus 로고    scopus 로고
    • The repulsive guidance molecule, RGMa, promotes retinal ganglion cell survival in vitro and in vivo
    • Koeberle PD, Tura A, Tassew NG, Schlichter LC, Monnier PP, (2010) The repulsive guidance molecule, RGMa, promotes retinal ganglion cell survival in vitro and in vivo. Neuroscience 169: 495-504.
    • (2010) Neuroscience , vol.169 , pp. 495-504
    • Koeberle, P.D.1    Tura, A.2    Tassew, N.G.3    Schlichter, L.C.4    Monnier, P.P.5
  • 30
    • 79955586868 scopus 로고    scopus 로고
    • Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation
    • Mirakaj V, Brown S, Laucher S, Steinl C, Klein G, et al. (2011) Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation. Proc Natl Acad Sci U S A 108: 6555-6560.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 6555-6560
    • Mirakaj, V.1    Brown, S.2    Laucher, S.3    Steinl, C.4    Klein, G.5
  • 31
    • 79953743514 scopus 로고    scopus 로고
    • RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis
    • Muramatsu R, Kubo T, Mori M, Nakamura Y, Fujita Y, et al. (2011) RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis. Nat Med 17: 488-494.
    • (2011) Nat Med , vol.17 , pp. 488-494
    • Muramatsu, R.1    Kubo, T.2    Mori, M.3    Nakamura, Y.4    Fujita, Y.5
  • 32
    • 79251564772 scopus 로고    scopus 로고
    • Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages
    • Xia Y, Cortez-Retamozo V, Niederkofler V, Salie R, Chen S, et al. (2011) Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages. J Immunol 186: 1369-1376.
    • (2011) J Immunol , vol.186 , pp. 1369-1376
    • Xia, Y.1    Cortez-Retamozo, V.2    Niederkofler, V.3    Salie, R.4    Chen, S.5
  • 33
    • 83455199106 scopus 로고    scopus 로고
    • The BMP coreceptor RGMb promotes while the endogenous BMP antagonist noggin reduces neurite outgrowth and peripheral nerve regeneration by modulating BMP signaling
    • Ma CH, Brenner GJ, Omura T, Samad OA, Costigan M, et al. (2011) The BMP coreceptor RGMb promotes while the endogenous BMP antagonist noggin reduces neurite outgrowth and peripheral nerve regeneration by modulating BMP signaling. J Neurosci 31: 18391-18400.
    • (2011) J Neurosci , vol.31 , pp. 18391-18400
    • Ma, C.H.1    Brenner, G.J.2    Omura, T.3    Samad, O.A.4    Costigan, M.5
  • 34
    • 63449122819 scopus 로고    scopus 로고
    • Lack of the bone morphogenetic protein BMP6 induces massive iron overload
    • Meynard D, Kautz L, Darnaud V, Canonne-Hergaux F, Coppin H, et al. (2009) Lack of the bone morphogenetic protein BMP6 induces massive iron overload. Nat Genet 41: 478-481.
    • (2009) Nat Genet , vol.41 , pp. 478-481
    • Meynard, D.1    Kautz, L.2    Darnaud, V.3    Canonne-Hergaux, F.4    Coppin, H.5
  • 35
    • 80054101329 scopus 로고    scopus 로고
    • Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice
    • Steinbicker AU, Bartnikas TB, Lohmeyer LK, Leyton P, Mayeur C, et al. (2011) Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice. Blood 118: 4224-4230.
    • (2011) Blood , vol.118 , pp. 4224-4230
    • Steinbicker, A.U.1    Bartnikas, T.B.2    Lohmeyer, L.K.3    Leyton, P.4    Mayeur, C.5
  • 36
    • 33644876815 scopus 로고    scopus 로고
    • A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
    • Wang RH, Li C, Xu X, Zheng Y, Xiao C, et al. (2005) A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression. Cell Metab 2: 399-409.
    • (2005) Cell Metab , vol.2 , pp. 399-409
    • Wang, R.H.1    Li, C.2    Xu, X.3    Zheng, Y.4    Xiao, C.5
  • 37
    • 37249010753 scopus 로고    scopus 로고
    • Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
    • Yu PB, Hong CC, Sachidanandan C, Babitt JL, Deng DY, et al. (2008) Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol 4: 33-41.
    • (2008) Nat Chem Biol , vol.4 , pp. 33-41
    • Yu, P.B.1    Hong, C.C.2    Sachidanandan, C.3    Babitt, J.L.4    Deng, D.Y.5
  • 38
    • 78049463632 scopus 로고    scopus 로고
    • BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice
    • Corradini E, Schmidt PJ, Meynard D, Garuti C, Montosi G, et al. (2010) BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice. Gastroenterology 139: 1721-1729.
    • (2010) Gastroenterology , vol.139 , pp. 1721-1729
    • Corradini, E.1    Schmidt, P.J.2    Meynard, D.3    Garuti, C.4    Montosi, G.5
  • 39
    • 80052647221 scopus 로고    scopus 로고
    • Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats
    • Theurl I, Schroll A, Sonnweber T, Nairz M, Theurl M, et al. (2011) Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats. Blood 118: 4977-4984.
    • (2011) Blood , vol.118 , pp. 4977-4984
    • Theurl, I.1    Schroll, A.2    Sonnweber, T.3    Nairz, M.4    Theurl, M.5
  • 40
    • 34547124340 scopus 로고    scopus 로고
    • Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4
    • Xia Y, Yu PB, Sidis Y, Beppu H, Bloch KD, et al. (2007) Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4. J Biol Chem 282: 18129-18140.
    • (2007) J Biol Chem , vol.282 , pp. 18129-18140
    • Xia, Y.1    Yu, P.B.2    Sidis, Y.3    Beppu, H.4    Bloch, K.D.5
  • 41
    • 46749158788 scopus 로고    scopus 로고
    • Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin
    • Xia Y, Babitt JL, Sidis Y, Chung RT, Lin HY, (2008) Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. Blood 111: 5195-5204.
    • (2008) Blood , vol.111 , pp. 5195-5204
    • Xia, Y.1    Babitt, J.L.2    Sidis, Y.3    Chung, R.T.4    Lin, H.Y.5
  • 42
    • 77950604264 scopus 로고    scopus 로고
    • Dragon enhances BMP signaling and increases transepithelial resistance in kidney epithelial cells
    • Xia Y, Babitt JL, Bouley R, Zhang Y, Da Silva N, et al. (2010) Dragon enhances BMP signaling and increases transepithelial resistance in kidney epithelial cells. J Am Soc Nephrol 21: 666-677.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 666-677
    • Xia, Y.1    Babitt, J.L.2    Bouley, R.3    Zhang, Y.4    Da Silva, N.5
  • 43
    • 0025672641 scopus 로고
    • Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone
    • Celeste AJ, Iannazzi JA, Taylor RC, Hewick RM, Rosen V, et al. (1990) Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone. Proc Natl Acad Sci U S A 87: 9843-9847.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 9843-9847
    • Celeste, A.J.1    Iannazzi, J.A.2    Taylor, R.C.3    Hewick, R.M.4    Rosen, V.5
  • 44
    • 0000304260 scopus 로고
    • Bone morphogenetic protein-9, a new member of the TGF-beta superfamily
    • Celeste AJ, Song JJ, Cox K, Rosen V, Wozeny JM (1994) Bone morphogenetic protein-9, a new member of the TGF-beta superfamily. J Bone Min Res 9[Suppl 1]: S136.
    • (1994) J Bone Min Res , vol.9 , Issue.SUPPL. 1
    • Celeste, A.J.1    Song, J.J.2    Cox, K.3    Rosen, V.4    Wozeny, J.M.5
  • 45
    • 21644461778 scopus 로고    scopus 로고
    • Crystal structure of BMP-9 and functional interactions with pro-region and receptors
    • Brown MA, Zhao Q, Baker KA, Naik C, Chen C, et al. (2005) Crystal structure of BMP-9 and functional interactions with pro-region and receptors. J Biol Chem 280: 25111-25118.
    • (2005) J Biol Chem , vol.280 , pp. 25111-25118
    • Brown, M.A.1    Zhao, Q.2    Baker, K.A.3    Naik, C.4    Chen, C.5
  • 46
    • 34547759860 scopus 로고    scopus 로고
    • Role of RGM coreceptors in bone morphogenetic protein signaling
    • Halbrooks PJ, Ding R, Wozney JM, Bain G, (2007) Role of RGM coreceptors in bone morphogenetic protein signaling. J Mol Signal 2: 4.
    • (2007) J Mol Signal , vol.2 , pp. 4
    • Halbrooks, P.J.1    Ding, R.2    Wozney, J.M.3    Bain, G.4
  • 47
    • 41849096388 scopus 로고    scopus 로고
    • Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domains
    • Yang F, West AP Jr, Allendorph GP, Choe S, Bjorkman PJ, (2008) Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domains. Biochemistry 47: 4237-4245.
    • (2008) Biochemistry , vol.47 , pp. 4237-4245
    • Yang, F.1    West Jr., A.P.2    Allendorph, G.P.3    Choe, S.4    Bjorkman, P.J.5
  • 48
    • 34250308049 scopus 로고    scopus 로고
    • Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin
    • Zhang AS, Anderson SA, Meyers KR, Hernandez C, Eisenstein RS, et al. (2007) Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin. J Biol Chem 282: 12547-12556.
    • (2007) J Biol Chem , vol.282 , pp. 12547-12556
    • Zhang, A.S.1    Anderson, S.A.2    Meyers, K.R.3    Hernandez, C.4    Eisenstein, R.S.5
  • 50
    • 84874756816 scopus 로고    scopus 로고
    • A novel validated enzyme-linked immunosorbent assay (ELISA) to quantify soluble hemojuvelin in mouse serum
    • doi: 10.3324/haematol.2012.070136
    • Chen W, Sun CC, Chen S, Meynard D, Babitt JL, et al. (2012) A novel validated enzyme-linked immunosorbent assay (ELISA) to quantify soluble hemojuvelin in mouse serum. Haematologica doi: 10.3324/haematol.2012.070136.
    • (2012) Haematologica
    • Chen, W.1    Sun, C.C.2    Chen, S.3    Meynard, D.4    Babitt, J.L.5
  • 51
    • 37349118993 scopus 로고    scopus 로고
    • Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand
    • Saremba S, Nickel J, Seher A, Kotzsch A, Sebald W, et al. (2008) Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand. FEBS J 275: 172-183.
    • (2008) FEBS J , vol.275 , pp. 172-183
    • Saremba, S.1    Nickel, J.2    Seher, A.3    Kotzsch, A.4    Sebald, W.5
  • 52
    • 78149304850 scopus 로고    scopus 로고
    • In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2
    • Maes K, Nemeth E, Roodman GD, Huston A, Esteve F, et al. (2010) In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2. Blood 116: 3635-3644.
    • (2010) Blood , vol.116 , pp. 3635-3644
    • Maes, K.1    Nemeth, E.2    Roodman, G.D.3    Huston, A.4    Esteve, F.5


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