Conformational states of the kinase Lck regulate clustering in early T cell signaling

Nature Immunology

Volumn 14, Issue 1, 2013, Pages 82-89

  Rossy, Jérémie ^a   Owen, Dylan M ^a   Williamson, David J ^a   Yang, Zhengmin ^a   Gaus, Katharina ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; MUTANT PROTEIN; PROTEIN KINASE LCK; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ZETA; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME CONFORMATION; ENZYME INACTIVATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; T LYMPHOCYTE; WILD TYPE;

ALLOSTERIC REGULATION; HUMANS; JURKAT CELLS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE MICRODOMAINS; MICROSCOPY, FLUORESCENCE; MUTANT PROTEINS; PROTEIN CONFORMATION; RECEPTOR CROSS-TALK; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES; TRANSGENES;

EID: 84871201282     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2488     Document Type: Article

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