Mammalian target of rapamycin complex 2 (mTORC2) regulates lps-induced expression of il-12 and il-23 in human dendritic cells

Journal of Leukocyte Biology

Volumn 97, Issue 6, 2015, Pages 1071-1080

  Wei, Wen Chi ^a   Liu, Chih Pin ^b   Yang, Wen Chin ^a   Shyur, Lie Fen ^a   Sheu, Jyh Horng ^c   Chen, Swey Shen ^d,e   Yang, Ning Sun ^a,f,g  

^a AGRICULTURAL BIOTECHNOLOGY RESEARCH CENTER   (Taiwan)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^c NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^d IgE Therapeutics Inc   (United States)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

^f NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^g NATIONAL CENTRAL UNIVERSITY   (Taiwan)

Author keywords

Cytopiloyne; NF kB; Th1; Th17

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CYTOPILOYNE; GAMMA INTERFERON; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN 1; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PLANT MEDICINAL PRODUCT; PROTEIN KINASE B; PROTEIN S6; RAPAMYCIN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CARRIER PROTEIN; GLUCOSIDE; IL23R PROTEIN, HUMAN; INTERLEUKIN RECEPTOR; MAPKAP1 PROTEIN, HUMAN; MTOR PROTEIN, HUMAN; MULTIPROTEIN COMPLEX; POLYACETYLENE DERIVATIVE; RICTOR PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL MATURATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RESPONSE; DENDRITIC CELL; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; TH2 CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MONOCYTE; PRIMARY CELL CULTURE;

MAMMALIA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARRIER PROTEINS; CELL DIFFERENTIATION; DENDRITIC CELLS; GENE EXPRESSION REGULATION; GLUCOSIDES; HUMANS; INTERLEUKIN-12; INTERLEUKIN-12 SUBUNIT P40; LIPOPOLYSACCHARIDES; MONOCYTES; MULTIPROTEIN COMPLEXES; NF-KAPPA B; POLYACETYLENES; PRIMARY CELL CULTURE; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, INTERLEUKIN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84930269016     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.2A0414-206RR     Document Type: Article

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