Autophagy plays an important role in triptolide-induced apoptosis in cardiomyocytes

Toxicology Letters

Volumn 236, Issue 3, 2015, Pages 168-183

  Zhou, Jie ^a   Xi, Chen ^a,b   Wang, Wenwen ^a   Yang, Yanqin ^a   Qiu, Yuwen ^a   Huang, Zhiying ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; Cardioprotective; Mitochondrion; Rapamycin; Triptolide

Indexed keywords

BECLIN 1; CASPASE 3; CHLOROQUINE; GLUTATHIONE; INTERLEUKIN 6; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRIPTOLIDE; TUMOR NECROSIS FACTOR ALPHA; DITERPENE; EPOXIDE; PHENANTHRENE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CARDIOTOXICITY; CELL DAMAGE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ANTAGONISM; DRUG MECHANISM; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEART PROTECTION; MALE; MOUSE; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMICALLY INDUCED; DRUG EFFECTS; HEART DISEASES; PHYSIOLOGY;

MUS; RATTUS; TRIPTERYGIUM WILFORDII;

ANIMALS; APOPTOSIS; AUTOPHAGY; CELL LINE; DITERPENES; EPOXY COMPOUNDS; HEART DISEASES; MICE; MICE, INBRED BALB C; MYOCYTES, CARDIAC; PHENANTHRENES; RATS; SIROLIMUS;

EID: 84930196921     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2015.05.013     Document Type: Article

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