Multifaceted effects of rapamycin on functional recovery after spinal cord injury in rats through autophagy promotion, anti-inflammation, and neuroprotection

Journal of Surgical Research

Volumn 179, Issue 1, 2013, Pages

  Chen, Hsien Chih ^a,b,c   Fong, Tsorng Harn ^d   Hsu, Peng Wei ^b   Chiu, Wen Ta ^c  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Autophagy; Inflammation; Neuroprotection; Rapamycin; Spinal cord injury

Indexed keywords

NEURON SPECIFIC NUCLEAR PROTEIN; RAPAMYCIN; S6 KINASE; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; AUTOPHAGY; CELL SURVIVAL; CONTROLLED STUDY; CONVALESCENCE; DRUG EFFECT; FEMALE; IMMUNOHISTOCHEMISTRY; LAMINECTOMY; LOCOMOTION; MICROGLIA; NERVE CELL; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SPINAL CORD INJURY; TREATMENT OUTCOME;

ANIMALS; ANTI-INFLAMMATORY AGENTS; AUTOPHAGY; FEMALE; LAMINECTOMY; MICROGLIA; MODELS, ANIMAL; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SIROLIMUS; SPINAL CORD INJURIES; TREATMENT OUTCOME;

EID: 84870676088     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2012.02.023     Document Type: Article

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