Inhibition of rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation

Neuroscience

Volumn 203, Issue , 2012, Pages 160-169

  Carloni, S ^a   Buonocore, G ^b   Longini, M ^b   Proietti, F ^b   Balduini, W ^a  

^a UNIVERSITY OF URBINO   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

Author keywords

3 methyladenine; Apoptosis; Autophagy; Ischemia; Necrosis; Rapamycin

Indexed keywords

3 METHYLADENINE; CASPASE 3; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAD; PROTEIN BAX; RAPAMYCIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; HYPOXIA; ISCHEMIA; MITOCHONDRION; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ADENINE; ANIMALS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL DEATH; MITOCHONDRIA; NECROSIS; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SIROLIMUS;

EID: 84856457651     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.12.021     Document Type: Article

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