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Volumn 33, Issue 2, 2015, Pages 279-286

Genomics, proteomics and metabolomics: Their emerging roles in the discovery and validation of rheumatoid arthritis biomarkers

Author keywords

Genomics; Metabolomics; Proteomics; Rheumatoid arthritis

Indexed keywords

BIOLOGICAL MARKER; MICRORNA; GENETIC MARKER;

EID: 84929940942     PISSN: 0392856X     EISSN: 1593098X     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (32)

References (78)
  • 1
    • 0035883897 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • LEE DM, WEINBLATT ME: Rheumatoid arthritis. Lancet 2001; 358: 903-11.
    • (2001) Lancet , vol.358 , pp. 903-911
    • Lee, D.M.1    Weinblatt, M.E.2
  • 2
    • 77953289185 scopus 로고    scopus 로고
    • The environment, geo-epidemiology, and autoimmune disease: Rheumatoid arthritis
    • TOBóN GJ, YOUINOU P, SARAUX A: The environment, geo-epidemiology, and autoimmune disease: Rheumatoid arthritis. J Autoimmun 2010; 35: 10-4.
    • (2010) J Autoimmun , vol.35 , pp. 10-14
    • Tobón, G.J.1    Youinou, P.2    Saraux, A.3
  • 3
    • 84867081740 scopus 로고    scopus 로고
    • Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis
    • AREND WP, FIRESTEIN GS: Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis. Nat Rev Rheumatol 2012; 8: 573-86.
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 573-586
    • Arend, W.P.1    Firestein, G.S.2
  • 4
    • 85027956586 scopus 로고    scopus 로고
    • Can rheumatoid arthritis be prevented?
    • DEANE KD: Can rheumatoid arthritis be prevented?. Best Pract Res Clin Rheumatol 2013; 27: 467-85.
    • (2013) Best Pract Res Clin Rheumatol , vol.27 , pp. 467-485
    • Deane, K.D.1
  • 5
    • 77956036473 scopus 로고    scopus 로고
    • 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative
    • ALETAHA D, NEOGI T, SILMAN AJ et al.: 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis 2010; 69: 1580-8.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1580-1588
    • Aletaha, D.1    Neogi, T.2    Silman, A.J.3
  • 6
    • 0034121235 scopus 로고    scopus 로고
    • Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins
    • MacGREGOR AJ, SNIEDER H, RIGBY AS et al.: Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis Rheum 2000; 43: 30-7.
    • (2000) Arthritis Rheum , vol.43 , pp. 30-37
    • Macgregor, A.J.1    Snieder, H.2    Rigby, A.S.3
  • 7
    • 34147219949 scopus 로고    scopus 로고
    • Prediction models for rheumatoid arthritis during diagnostic investigation: evaluation of combinations of rheumatoid factor, anti-citrullinated protein/peptide antibodies and the human leucocyte antigen-shared epitope
    • vander CRUYSSEN B, HOFMANN IE, PEENE I et al.: Prediction models for rheumatoid arthritis during diagnostic investigation: evaluation of combinations of rheumatoid factor, anti-citrullinated protein/peptide antibodies and the human leucocyte antigen-shared epitope. Ann Rheum Dis 2007; 66: 364-9.
    • (2007) Ann Rheum Dis , vol.66 , pp. 364-369
    • Vander Cruyssen, B.1    Hofmann, I.E.2    Peene, I.3
  • 8
    • 80054806901 scopus 로고    scopus 로고
    • Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage
    • SHI J, KNEVEL R, SUWANNALAI P et al.: Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage. Proc Natl Acad Sci USA 2011; 108: 17372-7.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 17372-17377
    • Shi, J.1    Knevel, R.2    Suwannalai, P.3
  • 10
    • 34547646716 scopus 로고    scopus 로고
    • Analytical and diagnostic characteristics of 11 2nd-and 3rd-generation immunoenzymatic methods for the detection of antibodies to citrullinated proteins
    • BIZZARO N, TONUTTI E, TOZZOLI R, VILLALTA D: Analytical and diagnostic characteristics of 11 2nd-and 3rd-generation immunoenzymatic methods for the detection of antibodies to citrullinated proteins. Clin Chem 2007; 53: 1527-33.
    • (2007) Clin Chem , vol.53 , pp. 1527-1533
    • Bizzaro, N.1    Tonutti, E.2    Tozzoli, R.3    Villalta, D.4
  • 11
    • 78049416309 scopus 로고    scopus 로고
    • Analytical approaches to metabolomics and applications to systems biology
    • WANG JH, BYUN J, PENNATHUR S: Analytical approaches to metabolomics and applications to systems biology. Semin Nephrol 2010; 30: 500-11.
    • (2010) Semin Nephrol , vol.30 , pp. 500-511
    • Wang, J.H.1    Byun, J.2    Pennathur, S.3
  • 12
    • 72149113840 scopus 로고    scopus 로고
    • Anti-citrullinated protein/peptide autoantibodies in association with genetic and environmental factors as indicators of disease outcome in rheumatoid arthritis
    • SZODORAY P, SZABO Z, KAPITANY A et al.: Anti-citrullinated protein/peptide autoantibodies in association with genetic and environmental factors as indicators of disease outcome in rheumatoid arthritis. Autoimmun Rev 2010; 9: 140-3.
    • (2010) Autoimmun Rev , vol.9 , pp. 140-143
    • Szodoray, P.1    Szabo, Z.2    Kapitany, A.3
  • 14
    • 84862776511 scopus 로고    scopus 로고
    • Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
    • RAYCHAUDHURI S, SANDOR C, STAHL EA et al.: Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat Genet 2012; 44: 291-6.
    • (2012) Nat Genet , vol.44 , pp. 291-296
    • Raychaudhuri, S.1    Sandor, C.2    Stahl, E.A.3
  • 15
    • 0023500817 scopus 로고
    • The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
    • GREGERSEN PK, SILVER J, WINCHESTER RJ: The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 1987; 30: 1205-13.
    • (1987) Arthritis Rheum , vol.30 , pp. 1205-1213
    • Gregersen, P.K.1    Silver, J.2    Winchester, R.J.3
  • 16
    • 84860918306 scopus 로고    scopus 로고
    • Antibodies against cyclic citrullinated peptides of IgG, IgA and IgM isotype and rheumatoid factor of IgM and IgA isotype are increased in unaffected members of multicase rheumatoid arthritis families from northern Sweden
    • ÄRLESTIG L, MULLAZEGI M., KOKKONEN H, ROCKLöV J, RöNELID J, DAHLQVIST SR: Antibodies against cyclic citrullinated peptides of IgG, IgA and IgM isotype and rheumatoid factor of IgM and IgA isotype are increased in unaffected members of multicase rheumatoid arthritis families from northern Sweden. Ann Rheum Dis 2012; 71: 825-9.
    • (2012) Ann Rheum Dis , vol.71 , pp. 825-829
    • Ärlestig, L.1    Mullazegi, M.2    Kokkonen, H.3    Rocklöv, J.4    Rönelid, J.5    Dahlqvist, S.R.6
  • 17
    • 73449140089 scopus 로고    scopus 로고
    • A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA
    • KOLFENBACH JR, DEANE KD, DERBER LA et al.: A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA. Arthritis Rheum 2009; 61: 1735-42.
    • (2009) Arthritis Rheum , vol.61 , pp. 1735-1742
    • Kolfenbach, J.R.1    Deane, K.D.2    Derber, L.A.3
  • 18
    • 58249097071 scopus 로고    scopus 로고
    • Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region
    • DING B, PADYUKOV L, LUNDSTRöM E et al.: Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region. Arthritis Rheum 2009; 60: 30-8.
    • (2009) Arthritis Rheum , vol.60 , pp. 30-38
    • Ding, B.1    Padyukov, L.2    Lundström, E.3
  • 19
    • 44649135985 scopus 로고    scopus 로고
    • Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus
    • LEE HS, LEE AT, CRISWELL LA et al.: Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus. Mol Med 2008; 14: 293-300.
    • (2008) Mol Med , vol.14 , pp. 293-300
    • Lee, H.S.1    Lee, A.T.2    Criswell, L.A.3
  • 20
    • 58249104988 scopus 로고    scopus 로고
    • Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci
    • VIGNAL C, BANSAL AT, BALDING DJ et al.: Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci. Arthritis Rheum 2009; 60: 53-62.
    • (2009) Arthritis Rheum , vol.60 , pp. 53-62
    • Vignal, C.1    Bansal, A.T.2    Balding, D.J.3
  • 21
    • 3242713277 scopus 로고    scopus 로고
    • A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
    • BEGOVICH AB, CARLTON VE, HONIGBERG LA et al.: A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet 2004; 75: 330-7.
    • (2004) Am J Hum Genet , vol.75 , pp. 330-337
    • Begovich, A.B.1    Carlton, V.E.2    Honigberg, L.A.3
  • 22
    • 28144441356 scopus 로고    scopus 로고
    • Replication of putative candidate-gene associations with rheumatoid arthritis in > 4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4
    • PLENGE RM, PADYUKOV L, REMMERS EF et al.: Replication of putative candidate-gene associations with rheumatoid arthritis in > 4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. Am J Hum Genet 2005; 77: 1044-60.
    • (2005) Am J Hum Genet , vol.77 , pp. 1044-1060
    • Plenge, R.M.1    Padyukov, L.2    Remmers, E.F.3
  • 23
    • 77952888454 scopus 로고    scopus 로고
    • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
    • STAHL EA, RAYCHAUDHURI S, REMMERS EF et al.: Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet 2010; 42: 508-14.
    • (2010) Nat Genet , vol.42 , pp. 508-514
    • Stahl, E.A.1    Raychaudhuri, S.2    Remmers, E.F.3
  • 24
    • 84870531924 scopus 로고    scopus 로고
    • High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
    • EYRE S, BOWES J, DIOGO D et al.: High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet 2012; 44: 1336-40.
    • (2012) Nat Genet , vol.44 , pp. 1336-1340
    • Eyre, S.1    Bowes, J.2    Diogo, D.3
  • 25
    • 84894288992 scopus 로고    scopus 로고
    • Genetics of rheumatoid arthritis contributes to biology and drug discovery
    • OKADA Y, WU D, TRYNKA G et al.: Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature 2014; 506: 376-81.
    • (2014) Nature , vol.506 , pp. 376-381
    • Okada, Y.1    Wu, D.2    Trynka, G.3
  • 26
    • 84873451584 scopus 로고    scopus 로고
    • RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritis
    • HERUTH DP, GIBSON M, GRIGORYEV DN, ZHANG LQ, YE SQ: RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritis. Cell Biosci 2012; 2: 43.
    • (2012) Cell Biosci , vol.2 , pp. 43
    • Heruth, D.P.1    Gibson, M.2    Grigoryev, D.N.3    Zhang, L.Q.4    Ye, S.Q.5
  • 27
    • 34548448091 scopus 로고    scopus 로고
    • Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity
    • GALLIGAN CL, BAIG E, BYKERK V, KEYSTONE EC, FISH EN: Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity. Genes Immun 2007; 8: 480-91.
    • (2007) Genes Immun , vol.8 , pp. 480-491
    • Galligan, C.L.1    Baig, E.2    Bykerk, V.3    Keystone, E.C.4    Fish, E.N.5
  • 28
    • 0036289709 scopus 로고    scopus 로고
    • Gene expression profile analysis of rheumatoid synovial fibroblast cultures revealing the overexpression of genes responsible for tumor-like growth of rheumatoid synovium
    • WATANABE N, ANDO K, YOSHIDA S et al.: Gene expression profile analysis of rheumatoid synovial fibroblast cultures revealing the overexpression of genes responsible for tumor-like growth of rheumatoid synovium. Biochem Biophys Res Commun 2002; 294: 1121-9.
    • (2002) Biochem Biophys Res Commun , vol.294 , pp. 1121-1129
    • Watanabe, N.1    Ando, K.2    Yoshida, S.3
  • 29
    • 78650045543 scopus 로고    scopus 로고
    • The transcriptional response of normal and rheumatoid arthritis synovial fibroblasts to hypoxia
    • DEL REY MJ, IZQUIERDO E, USATEGUI A et al.: The transcriptional response of normal and rheumatoid arthritis synovial fibroblasts to hypoxia. Arthritis Rheum 2010; 62: 3584-94.
    • (2010) Arthritis Rheum , vol.62 , pp. 3584-3594
    • Del Rey, M.J.1    Izquierdo, E.2    Usategui, A.3
  • 30
    • 59249107052 scopus 로고    scopus 로고
    • DNA methylation profiles in monozygotic and dizygotic twins
    • KAMINSKY ZA, TANG T, WANG SC et al.: DNA methylation profiles in monozygotic and dizygotic twins. Nat Genet 2009; 41: 240-5.
    • (2009) Nat Genet , vol.41 , pp. 240-245
    • Kaminsky, Z.A.1    Tang, T.2    Wang, S.C.3
  • 31
    • 84901928838 scopus 로고    scopus 로고
    • Genetic and epigenetic predictors of responsiveness to treatment in RA
    • PLANT D, WILSON AG, BARTON A: Genetic and epigenetic predictors of responsiveness to treatment in RA. Nat Rev 2014; 10: 329-37.
    • (2014) Nat Rev , vol.10 , pp. 329-337
    • Plant, D.1    Wilson, A.G.2    Barton, A.3
  • 33
    • 49449106856 scopus 로고    scopus 로고
    • Methylation status of a single CpG site in the IL-6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis
    • NILE CJ, READ RC, AKIL M, DUFF GW, WILSON AG: Methylation status of a single CpG site in the IL-6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis Rheum 2008; 58: 2686-93.
    • (2008) Arthritis Rheum , vol.58 , pp. 2686-2693
    • Nile, C.J.1    Read, R.C.2    Akil, M.3    Duff, G.W.4    Wilson, A.G.5
  • 35
    • 0025666735 scopus 로고
    • Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis
    • RICHARDSON B, SCHEINBART L, STRAHLER J, GROSS L, HANASH S, JOHNSON M: Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum 1990; 33: 1665-73.
    • (1990) Arthritis Rheum , vol.33 , pp. 1665-1673
    • Richardson, B.1    Scheinbart, L.2    Strahler, J.3    Gross, L.4    Hanash, S.5    Johnson, M.6
  • 36
    • 84873576566 scopus 로고    scopus 로고
    • Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
    • LIU Y, ARYEE MJ, PADYUKOV L et al.: Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nature Biotech 2013; 31: 142-7.
    • (2013) Nature Biotech , vol.31 , pp. 142-147
    • Liu, Y.1    Aryee, M.J.2    Padyukov, L.3
  • 37
    • 0030205396 scopus 로고    scopus 로고
    • DNA hypomethylation in inflammatory arthritis: reversal with methotrexate
    • KIM YI, LOGAN JW, MASON JB, ROUBENOFF R: DNA hypomethylation in inflammatory arthritis: reversal with methotrexate. J Lab Clin Med 1996; 128: 165-72.
    • (1996) J Lab Clin Med , vol.128 , pp. 165-172
    • Kim, Y.I.1    Logan, J.W.2    Mason, J.B.3    Roubenoff, R.4
  • 38
    • 84874962763 scopus 로고    scopus 로고
    • Genome-scale case-control analysis of CD4+ T-cell DNA methylation in juvenile idiopathic arthritis reveals potential targets involved in disease
    • ELLIS JA, MUNRO JE, CHAVEZ RA et al.: Genome-scale case-control analysis of CD4+ T-cell DNA methylation in juvenile idiopathic arthritis reveals potential targets involved in disease. Clin Epigenetics 2012; 4: 20.
    • (2012) Clin Epigenetics , vol.4 , pp. 20
    • Ellis, J.A.1    Munro, J.E.2    Chavez, R.A.3
  • 40
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • KOUZARIDES T: Chromatin modifications and their function. Cell 2007; 128: 693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 42
    • 84877602531 scopus 로고    scopus 로고
    • The ascent of acetylation in the epigenetics of rheumatoid arthritis
    • GRABIEC AM, REEDQUIST KA: The ascent of acetylation in the epigenetics of rheumatoid arthritis. Nat Rev 2013; 9: 311-18.
    • (2013) Nat Rev , vol.9 , pp. 311-318
    • Grabiec, A.M.1    Reedquist, K.A.2
  • 44
    • 77954286123 scopus 로고    scopus 로고
    • Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis
    • KAWABATA T, NISHIDA K, TAKASUGI K et al.: Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis. Arthritis Res Ther 2010; 12: R133.
    • (2010) Arthritis Res Ther , vol.12 , pp. R133
    • Kawabata, T.1    Nishida, K.2    Takasugi, K.3
  • 45
    • 84857233842 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocytes and macrophage IL-6 production by accelerating mRNA decay
    • GRABIEC AM, KORCHYNSKY O, TAK PP, REEDQUIST KA: Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocytes and macrophage IL-6 production by accelerating mRNA decay. Ann Rheum Dis 2012; 71: 424-31.
    • (2012) Ann Rheum Dis , vol.71 , pp. 424-431
    • Grabiec, A.M.1    Korchynsky, O.2    Tak, P.P.3    Reedquist, K.A.4
  • 46
    • 84890017303 scopus 로고    scopus 로고
    • Immune-mediated pore-forming pathways induce celular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis
    • ROMERO V, FERT-BOBER J, NIGROVIC PA et al.: Immune-mediated pore-forming pathways induce celular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis. Sci Transl Med 2013; 5: 209ra150.
    • (2013) Sci Transl Med , vol.5
    • Romero, V.1    Fert-Bober, J.2    Nigrovic, P.A.3
  • 47
    • 84902057700 scopus 로고    scopus 로고
    • Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: analysis of underlying signal transduction pathways and potential diagnostic utility
    • CHOWDHURY CS, GIAGLIS S, WALKER UA, BUSER A, HAHN S, HASLER P: Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: analysis of underlying signal transduction pathways and potential diagnostic utility. Arthritis Res Ther 2014; 16: R122.
    • (2014) Arthritis Res Ther , vol.16 , pp. R122
    • Chowdhury, C.S.1    Giaglis, S.2    Walker, U.A.3    Buser, A.4    Hahn, S.5    Hasler, P.6
  • 49
    • 52249094653 scopus 로고    scopus 로고
    • Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients
    • PAULEY KM, SATOH M, CHAN AL, BUBB MR, REEVES WH, CHAN EK: Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Ther 2008; 10: R101.
    • (2008) Arthritis Res Ther , vol.10 , pp. R101
    • Pauley, K.M.1    Satoh, M.2    Chan, A.L.3    Bubb, M.R.4    Reeves, W.H.5    Chan, E.K.6
  • 50
    • 74449090482 scopus 로고    scopus 로고
    • miR-223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis
    • FULCI V, SCAPPUCCI G, SEBASTIANI GD et al.: miR-223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis. Human Immunol 2010; 71: 206-11.
    • (2010) Human Immunol , vol.71 , pp. 206-211
    • Fulci, V.1    Scappucci, G.2    Sebastiani, G.D.3
  • 51
    • 77952086523 scopus 로고    scopus 로고
    • Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis
    • MURATA K, YOSHITOMI H, TANIDA S et al.: Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis. Arthritis Res Ther 2010; 12: R86.
    • (2010) Arthritis Res Ther , vol.12 , pp. R86
    • Murata, K.1    Yoshitomi, H.2    Tanida, S.3
  • 52
    • 0034095972 scopus 로고    scopus 로고
    • The current state of two-dimensional electrophoresis with immobilized pH gradients
    • GORG A, BOGUTH G, HARDER A, SCHEIBE B, WILDGRUBER R, WEISS W: The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 2000; 21: 1037-53.
    • (2000) Electrophoresis , vol.21 , pp. 1037-1053
    • Gorg, A.1    Boguth, G.2    Harder, A.3    Scheibe, B.4    Wildgruber, R.5    Weiss, W.6
  • 53
    • 0034662907 scopus 로고    scopus 로고
    • Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology
    • GYGI SP, ZHANG Y, ROCHON Y, AEBERSOLD R: Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology. Proc Natl Acad Sci 2000; 97: 9390-5.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 9390-9395
    • Gygi, S.P.1    Zhang, Y.2    Rochon, Y.3    Aebersold, R.4
  • 54
    • 84921977401 scopus 로고    scopus 로고
    • Pathway and network analysis in proteomics
    • WU X, HASAN MA, CHEN JY: Pathway and network analysis in proteomics. J Theor Biol 2014; 362: 44-52.
    • (2014) J Theor Biol , vol.362 , pp. 44-52
    • Wu, X.1    Hasan, M.A.2    Chen, J.Y.3
  • 55
    • 19944432197 scopus 로고    scopus 로고
    • Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents
    • ROSS PL, HUANG YN, MARCHESE JN et al.: Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol Cell Proteomics 2004; 3: 1154-69.
    • (2004) Mol Cell Proteomics , vol.3 , pp. 1154-1169
    • Ross, P.L.1    Huang, Y.N.2    Marchese, J.N.3
  • 56
    • 84893084416 scopus 로고    scopus 로고
    • Comparative proteomic analyses of synovial fluids and serums from rheumatoid arthritis patients
    • NOH R, PARK SG, JU JH et al.: Comparative proteomic analyses of synovial fluids and serums from rheumatoid arthritis patients. J Microbiol Biotechnol 2014; 24: 119-26.
    • (2014) J Microbiol Biotechnol , vol.24 , pp. 119-126
    • Noh, R.1    Park, S.G.2    Ju, J.H.3
  • 57
    • 62749090550 scopus 로고    scopus 로고
    • Study of the human plasma proteome of rheumatoid arthritis
    • ZHENG X, WU SL, HINCAPIE M, HANCOCK WS: Study of the human plasma proteome of rheumatoid arthritis. J Chromatogr A 2009; 1216: 3538-45.
    • (2009) J Chromatogr A , vol.1216 , pp. 3538-3545
    • Zheng, X.1    Wu, S.L.2    Hincapie, M.3    Hancock, W.S.4
  • 58
    • 84861347338 scopus 로고    scopus 로고
    • Differential protein profiling of synovial fluid from rheumatoid arthritis and osteoarthritis patients using LC-MALDI TOF/TOF
    • MATEOS J, LOURIDO L, FERNáNDEZ-PUENTE P et al.: Differential protein profiling of synovial fluid from rheumatoid arthritis and osteoarthritis patients using LC-MALDI TOF/TOF. J Proteomics 2012; 75: 2869-78.
    • (2012) J Proteomics , vol.75 , pp. 2869-2878
    • Mateos, J.1    Lourido, L.2    Fernández-Puente, P.3
  • 59
    • 84903735770 scopus 로고    scopus 로고
    • Differential proteomic analysis of synovial fluid from rheumatoid arthritis and osteoarthritis patients
    • BALAKRISHNAN L, BHATTACHARJEE M, AHMAD S et al.: Differential proteomic analysis of synovial fluid from rheumatoid arthritis and osteoarthritis patients. Clin Proteomics 2014; 11: 1.
    • (2014) Clin Proteomics , vol.11 , pp. 1
    • Balakrishnan, L.1    Bhattacharjee, M.2    Ahmad, S.3
  • 60
    • 84883509256 scopus 로고    scopus 로고
    • Proteomic analysis of synovial fibroblast-like synoviocytes from rheumatoid arthritis
    • LI XJ, XU M, ZHAO XQ et al.: Proteomic analysis of synovial fibroblast-like synoviocytes from rheumatoid arthritis. Clin Exp Rheumatol 2013; 31: 552-8.
    • (2013) Clin Exp Rheumatol , vol.31 , pp. 552-558
    • Li, X.J.1    Xu, M.2    Zhao, X.Q.3
  • 64
    • 18844406001 scopus 로고    scopus 로고
    • Measuring the metabolome: current analytical technologies
    • DUNN WB, BAILEY NJ, JOHNSON HE: Measuring the metabolome: current analytical technologies. Analyst 2005; 130: 606-25.
    • (2005) Analyst , vol.130 , pp. 606-625
    • Dunn, W.B.1    Bailey, N.J.2    Johnson, H.E.3
  • 65
    • 48949117000 scopus 로고    scopus 로고
    • Utility of separation science in metabolomic studies
    • ISSAQ HJ, ABBOTT E, VEENSTRA TD: Utility of separation science in metabolomic studies. J Sep Sci 2008; 31: 1936-47.
    • (2008) J Sep Sci , vol.31 , pp. 1936-1947
    • Issaq, H.J.1    Abbott, E.2    Veenstra, T.D.3
  • 66
    • 0043069547 scopus 로고    scopus 로고
    • Understanding 'global' systems biology: metabonomics and the continuum of metabolism
    • NICHOLSON JK, WILSON ID: Understanding 'global' systems biology: metabonomics and the continuum of metabolism. Nat Rev Drug Discov 2003; 2: 668-76.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 668-676
    • Nicholson, J.K.1    Wilson, I.D.2
  • 67
    • 0346366560 scopus 로고    scopus 로고
    • Application of high-throughput Fourier-transform infrared spectroscopy in toxicology studies: contribution to a study on the development of an animal model for idiosyncratic toxicity
    • HARRIGAN GG, LAPLANTE RH, COSMA GN et al.: Application of high-throughput Fourier-transform infrared spectroscopy in toxicology studies: contribution to a study on the development of an animal model for idiosyncratic toxicity. Toxicol Lett 2004; 146: 197-205.
    • (2004) Toxicol Lett , vol.146 , pp. 197-205
    • Harrigan, G.G.1    Laplante, R.H.2    Cosma, G.N.3
  • 68
    • 1642312092 scopus 로고    scopus 로고
    • High-throughput metabolic fingerprinting of legume silage fermentations via Fourier transforms infrared spectroscopy and chemometrics
    • JOHNSON HE, BROADHURST D, KELL DB, THEODOROU MK, MERRY RJ, GRIFFITH GW: High-throughput metabolic fingerprinting of legume silage fermentations via Fourier transforms infrared spectroscopy and chemometrics. Appl Environm Microbiol 2004; 70: 1583-92.
    • (2004) Appl Environm Microbiol , vol.70 , pp. 1583-1592
    • Johnson, H.E.1    Broadhurst, D.2    Kell, D.B.3    Theodorou, M.K.4    Merry, R.J.5    Griffith, G.W.6
  • 69
    • 0345490738 scopus 로고    scopus 로고
    • A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects
    • LENZ EM, BRIGHT J, WILSON ID, MORGAN SR, NASH A: A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects. J Pharmac Biomed Anal 2003; 33: 1103-15.
    • (2003) J Pharmac Biomed Anal , vol.33 , pp. 1103-1115
    • Lenz, E.M.1    Bright, J.2    Wilson, I.D.3    Morgan, S.R.4    Nash, A.5
  • 70
    • 79551689052 scopus 로고    scopus 로고
    • Diagnostic properties of metabolic perturbations in rheumatoid arthritis
    • MADSEN RK, LUNDSTEDT T, GABRIELSSON J et al.: Diagnostic properties of metabolic perturbations in rheumatoid arthritis. Arthr Res Ther 2011; 13: R19.
    • (2011) Arthr Res Ther , vol.13 , pp. R19
    • Madsen, R.K.1    Lundstedt, T.2    Gabrielsson, J.3
  • 71
    • 0027405652 scopus 로고
    • An investigation of the abnormal metabolic status of synovial fluid from patients with rheumatoid arthritis by high field proton nuclear magnetic resonance spectroscopy
    • NAUGTON D, WHELAN M, SMITH EC, WILLIAMS R, BLAKE DR, GROOTVELD M: An investigation of the abnormal metabolic status of synovial fluid from patients with rheumatoid arthritis by high field proton nuclear magnetic resonance spectroscopy. FEBS Lett 1993; 317: 135-8.
    • (1993) FEBS Lett , vol.317 , pp. 135-138
    • Naugton, D.1    Whelan, M.2    Smith, E.C.3    Williams, R.4    Blake, D.R.5    Grootveld, M.6
  • 72
    • 84898546574 scopus 로고    scopus 로고
    • Plasma metabolomics reveals a potential panel of biomarkers for early diagnosis in acute coronary syndrome
    • LABORDE CM, MOURIñO-ALVAREZ L, POSADA-AYALA M et al.: Plasma metabolomics reveals a potential panel of biomarkers for early diagnosis in acute coronary syndrome. Metabolomics 2014; 10: 414-24.
    • (2014) Metabolomics , vol.10 , pp. 414-424
    • Laborde, C.M.1    Mouriño-Alvarez, L.2    Posada-Ayala, M.3
  • 73
    • 84866316346 scopus 로고    scopus 로고
    • Characterization of rheumatoid arthritis subtypes using symptom profiles, clinical chemistry and metabolomics measurements
    • van WIETMARSCHEN HA, DAI W, van der KOOIJ AJ et al.: Characterization of rheumatoid arthritis subtypes using symptom profiles, clinical chemistry and metabolomics measurements. PLoS One 2012; 7: e44331.
    • (2012) PLoS One , vol.7
    • Van Wietmarschen, H.A.1    Dai, W.2    Van Der Kooij, A.J.3
  • 74
    • 0028929853 scopus 로고
    • Synovial fluid lipids and apolipoproteins: a contemporary perspective
    • PRETE PE, GURAKAR-OSBORNE A, KASHYAP ML: Synovial fluid lipids and apolipoproteins: a contemporary perspective. Biorheology 1995; 32: 1-16.
    • (1995) Biorheology , vol.32 , pp. 1-16
    • Prete, P.E.1    Gurakar-Osborne, A.2    Kashyap, M.L.3
  • 75
    • 0023149183 scopus 로고
    • Syn-ovial fluid lipid abnormalities in various disease states: review and classification
    • WISE CM, WHITE RE, AGUDELO CA: Syn-ovial fluid lipid abnormalities in various disease states: review and classification. Semin Arthritis Rheum 1987; 16: 222-30.
    • (1987) Semin Arthritis Rheum , vol.16 , pp. 222-230
    • Wise, C.M.1    White, R.E.2    Agudelo, C.A.3
  • 76
    • 84865281324 scopus 로고    scopus 로고
    • Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC-MS/MS
    • GIERA M, IOAN-FACSINAY A, TOES R et al.: Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC-MS/MS. Biochim Biophys Acta 2012; 1821: 1415-24.
    • (2012) Biochim Biophys Acta , vol.1821 , pp. 1415-1424
    • Giera, M.1    Ioan-Facsinay, A.2    Toes, R.3
  • 77
    • 84863737272 scopus 로고    scopus 로고
    • Synovial fluid metabolomics in different forms of arthritis assessed by nuclear magnetic resonance spectroscopy
    • HüGLE T, KOVACS H, HEINEN IA et al.: Synovial fluid metabolomics in different forms of arthritis assessed by nuclear magnetic resonance spectroscopy. Clin Exp Rheumatol 2012; 30: 240-5.
    • (2012) Clin Exp Rheumatol , vol.30 , pp. 240-245
    • Hügle, T.1    Kovacs, H.2    Heinen, I.A.3
  • 78
    • 84872323563 scopus 로고    scopus 로고
    • Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWAS contribute to risk of rheumatoid arthritis
    • DIOGO D, KURREEMAN F, STAHL EA et al.: Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWAS contribute to risk of rheumatoid arthritis. Am J Hum Genet 2013; 92: 15-27.
    • (2013) Am J Hum Genet , vol.92 , pp. 15-27
    • Diogo, D.1    Kurreeman, F.2    Stahl, E.A.3


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