메뉴 건너뛰기




Volumn 6, Issue 4, 2011, Pages

Rapid temporal control of foxp3 protein degradation by sirtuin-1

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; SIRTUIN 4; SIRTUIN 5; SIRTUIN 6; SIRTUIN 7; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; SIRT1 PROTEIN, HUMAN;

EID: 79955438868     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019047     Document Type: Article
Times cited : (103)

References (39)
  • 1
    • 73449117582 scopus 로고    scopus 로고
    • Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells
    • Wang L, de Zoeten EF, Greene MI, Hancock WW, (2009) Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells. Nat Rev Drug Discov 8: 969-981.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 969-981
    • Wang, L.1    de Zoeten, E.F.2    Greene, M.I.3    Hancock, W.W.4
  • 2
    • 75449114277 scopus 로고    scopus 로고
    • Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice
    • de Zoeten EF, Wang L, Sai H, Dillmann WH, Hancock WW, (2010) Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice. Gastroenterology 138: 583-594.
    • (2010) Gastroenterology , vol.138 , pp. 583-594
    • de Zoeten, E.F.1    Wang, L.2    Sai, H.3    Dillmann, W.H.4    Hancock, W.W.5
  • 3
    • 70349385423 scopus 로고    scopus 로고
    • Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis
    • Saouaf SJ, Li B, Zhang G, Shen Y, Furuuchi N, et al. (2009) Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis. Exp Mol Pathol 87: 99-104.
    • (2009) Exp Mol Pathol , vol.87 , pp. 99-104
    • Saouaf, S.J.1    Li, B.2    Zhang, G.3    Shen, Y.4    Furuuchi, N.5
  • 4
    • 35948980739 scopus 로고    scopus 로고
    • Deacetylase inhibition promotes the generation and function of regulatory T cells
    • Tao R, de Zoeten EF, Ozkaynak E, Chen C, Wang L, et al. (2007) Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med 13: 1299-1307.
    • (2007) Nat Med , vol.13 , pp. 1299-1307
    • Tao, R.1    de Zoeten, E.F.2    Ozkaynak, E.3    Chen, C.4    Wang, L.5
  • 5
    • 77649225958 scopus 로고    scopus 로고
    • Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization
    • van Loosdregt J, Vercoulen Y, Guichelaar T, Gent YY, Beekman JM, et al. (2010) Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization. Blood 115: 965-974.
    • (2010) Blood , vol.115 , pp. 965-974
    • van Loosdregt, J.1    Vercoulen, Y.2    Guichelaar, T.3    Gent, Y.Y.4    Beekman, J.M.5
  • 6
    • 34248379172 scopus 로고    scopus 로고
    • FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression
    • Li B, Samanta A, Song X, Iacono KT, Bembas K, et al. (2007) FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression. Proc Natl Acad Sci USA 104: 4571-4576.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 4571-4576
    • Li, B.1    Samanta, A.2    Song, X.3    Iacono, K.T.4    Bembas, K.5
  • 7
    • 52949138267 scopus 로고    scopus 로고
    • TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3
    • Samanta A, Li B, Song X, Bembas K, Zhang G, et al. (2008) TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3. Proc Natl Acad Sci USA 105: 14023-14027.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14023-14027
    • Samanta, A.1    Li, B.2    Song, X.3    Bembas, K.4    Zhang, G.5
  • 8
    • 78049240315 scopus 로고    scopus 로고
    • Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function
    • Xiao Y, Li B, Zhou Z, Hancock WW, Zhang H, et al. (2010) Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function. Curr Opin Immunol 22: 583-591.
    • (2010) Curr Opin Immunol , vol.22 , pp. 583-591
    • Xiao, Y.1    Li, B.2    Zhou, Z.3    Hancock, W.W.4    Zhang, H.5
  • 9
    • 79952274915 scopus 로고    scopus 로고
    • Sirtuin-1 Targeting Promotes Foxp3+ T-Regulatory Cell Function And Prolongs Allograft Survival
    • Beier UH, Wang L, Bhatti TR, Liu Y, Han R, et al. (2011) Sirtuin-1 Targeting Promotes Foxp3+ T-Regulatory Cell Function And Prolongs Allograft Survival. Mol Cell Biol.
    • (2011) Mol Cell Biol
    • Beier, U.H.1    Wang, L.2    Bhatti, T.R.3    Liu, Y.4    Han, R.5
  • 10
    • 0028841317 scopus 로고
    • The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability
    • Brachmann CB, Sherman JM, Devine SE, Cameron EE, Pillus L, et al. (1995) The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes Dev 9: 2888-2902.
    • (1995) Genes Dev , vol.9 , pp. 2888-2902
    • Brachmann, C.B.1    Sherman, J.M.2    Devine, S.E.3    Cameron, E.E.4    Pillus, L.5
  • 11
    • 26244436281 scopus 로고    scopus 로고
    • Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
    • Michishita E, Park JY, Burneskis JM, Barrett JC, Horikawa I, (2005) Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 16: 4623-4635.
    • (2005) Mol Biol Cell , vol.16 , pp. 4623-4635
    • Michishita, E.1    Park, J.Y.2    Burneskis, J.M.3    Barrett, J.C.4    Horikawa, I.5
  • 12
    • 0035913903 scopus 로고    scopus 로고
    • hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
    • Vaziri H, Dessain SK, Ng EE, Imai SI, Frye RA, et al. (2001) hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107: 149-159.
    • (2001) Cell , vol.107 , pp. 149-159
    • Vaziri, H.1    Dessain, S.K.2    Ng, E.E.3    Imai, S.I.4    Frye, R.A.5
  • 13
    • 51649112590 scopus 로고    scopus 로고
    • sirt1-null mice develop an autoimmune-like condition
    • Sequeira J, Boily G, Bazinet S, Saliba S, He X, et al. (2008) sirt1-null mice develop an autoimmune-like condition. Exp Cell Res 314: 3069-3074.
    • (2008) Exp Cell Res , vol.314 , pp. 3069-3074
    • Sequeira, J.1    Boily, G.2    Bazinet, S.3    Saliba, S.4    He, X.5
  • 14
    • 70349440053 scopus 로고    scopus 로고
    • The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice
    • Zhang J, Lee SM, Shannon S, Gao B, Chen W, et al. (2009) The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice. J Clin Invest 119: 3048-3058.
    • (2009) J Clin Invest , vol.119 , pp. 3048-3058
    • Zhang, J.1    Lee, S.M.2    Shannon, S.3    Gao, B.4    Chen, W.5
  • 15
    • 33745889628 scopus 로고    scopus 로고
    • Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
    • Schwer B, Bunkenborg J, Verdin RO, Andersen JS, Verdin E, (2006) Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2. Proc Natl Acad Sci USA. 103: 10224-10229.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 10224-10229
    • Schwer, B.1    Bunkenborg, J.2    Verdin, R.O.3    Andersen, J.S.4    Verdin, E.5
  • 16
    • 33749595579 scopus 로고    scopus 로고
    • The chemokine and chemokine receptor profile of infiltrating cells in the wall of arteries with cardiac allograft vasculopathy is indicative of a memory T-helper 1 response
    • van Loosdregt J, van Oosterhout MF, Bruggink AH, van Wichen DF, van Kuik J, (2006) The chemokine and chemokine receptor profile of infiltrating cells in the wall of arteries with cardiac allograft vasculopathy is indicative of a memory T-helper 1 response. Circulation 114: 1599-1607.
    • (2006) Circulation , vol.114 , pp. 1599-1607
    • van Loosdregt, J.1    van Oosterhout, M.F.2    Bruggink, A.H.3    van Wichen, D.F.4    van Kuik, J.5
  • 17
    • 20744448187 scopus 로고    scopus 로고
    • Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity
    • Feng L, Lin T, Uranishi H, Gu W, Xu Y, (2005) Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity. Mol Cell Biol 25: 5389-5395.
    • (2005) Mol Cell Biol , vol.25 , pp. 5389-5395
    • Feng, L.1    Lin, T.2    Uranishi, H.3    Gu, W.4    Xu, Y.5
  • 18
    • 0036753547 scopus 로고    scopus 로고
    • Control of Smad7 stability by competition between acetylation and ubiquitination
    • Gronroos E, Hellman U, Heldin CH, Ericsson J, (2002) Control of Smad7 stability by competition between acetylation and ubiquitination. Mol Cell 10: 483-493.
    • (2002) Mol Cell , vol.10 , pp. 483-493
    • Gronroos, E.1    Hellman, U.2    Heldin, C.H.3    Ericsson, J.4
  • 19
    • 33645230001 scopus 로고    scopus 로고
    • Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1)
    • Zhao Y, Lu S, Wu L, Chai G, Wang H, et al. (2006) Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1). Mol Cell Biol 26: 2782-2790.
    • (2006) Mol Cell Biol , vol.26 , pp. 2782-2790
    • Zhao, Y.1    Lu, S.2    Wu, L.3    Chai, G.4    Wang, H.5
  • 20
    • 35348980724 scopus 로고    scopus 로고
    • SIRT1 controls endothelial angiogenic functions during vascular growth
    • Potente M, Ghaeni L, Baldessari D, Mostoslavsky R, Rossig L, et al. (2007) SIRT1 controls endothelial angiogenic functions during vascular growth. Genes Dev 21: 2644-2658.
    • (2007) Genes Dev , vol.21 , pp. 2644-2658
    • Potente, M.1    Ghaeni, L.2    Baldessari, D.3    Mostoslavsky, R.4    Rossig, L.5
  • 21
    • 77955489675 scopus 로고    scopus 로고
    • Nicotinamide phosphoribosyltransferase/sirtuin 1 pathway is involved in human immunodeficiency virus type 1 Tat-mediated long terminal repeat transactivation
    • Zhang HS, Sang WW, Wang YO, Liu W, (2010) Nicotinamide phosphoribosyltransferase/sirtuin 1 pathway is involved in human immunodeficiency virus type 1 Tat-mediated long terminal repeat transactivation. J Cell Biochem 110: 1464-1470.
    • (2010) J Cell Biochem , vol.110 , pp. 1464-1470
    • Zhang, H.S.1    Sang, W.W.2    Wang, Y.O.3    Liu, W.4
  • 22
    • 33847242598 scopus 로고    scopus 로고
    • Foxp3 occupancy and regulation of key target genes during T-cell stimulation
    • Marson A, Kretschmer K, Frampton GM, Jacobsen ES, Polansky JK, et al. (2007) Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature 445: 931-935.
    • (2007) Nature , vol.445 , pp. 931-935
    • Marson, A.1    Kretschmer, K.2    Frampton, G.M.3    Jacobsen, E.S.4    Polansky, J.K.5
  • 23
    • 27644449311 scopus 로고    scopus 로고
    • The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs
    • Allan SE, Passerini L, Bacchetta R, Crellin N, Dai M, et al. (2005) The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs. J Clin Invest 115: 3276-3284.
    • (2005) J Clin Invest , vol.115 , pp. 3276-3284
    • Allan, S.E.1    Passerini, L.2    Bacchetta, R.3    Crellin, N.4    Dai, M.5
  • 24
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY, (2003) Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4: 330-336.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 25
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F, (2003) An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 4: 337-342.
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 26
    • 34247271308 scopus 로고    scopus 로고
    • Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
    • Williams LM, Rudensky AY, (2007) Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat Immunol 8: 277-284.
    • (2007) Nat Immunol , vol.8 , pp. 277-284
    • Williams, L.M.1    Rudensky, A.Y.2
  • 27
    • 33646240855 scopus 로고    scopus 로고
    • Single-cell analysis of normal and FOXP3-mutant human T cells:FOXP3 expression without regulatory T cell development
    • Gavin MA, Torgerson TR, Houston E, DeRoos P, Ho WY, et al. (2006) Single-cell analysis of normal and FOXP3-mutant human T cells:FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci USA 103: 6659-6664.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6659-6664
    • Gavin, M.A.1    Torgerson, T.R.2    Houston, E.3    deRoos, P.4    Ho, W.Y.5
  • 28
    • 33846375082 scopus 로고    scopus 로고
    • Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells
    • Wang J, Ioan-Facsinay A, van d V, Huizinga TW, Toes RE, (2007) Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells. Eur J Immunol 37: 129-138.
    • (2007) Eur J Immunol , vol.37 , pp. 129-138
    • Wang, J.1    Ioan-Facsinay, A.2    van d, V.3    Huizinga, T.W.4    Toes, R.E.5
  • 29
    • 77955277730 scopus 로고    scopus 로고
    • Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs
    • Akimova T, Ge G, Golovina T, Mikheeva T, Wang L, et al. (2010) Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs. Clin Immunol 136: 348-363.
    • (2010) Clin Immunol , vol.136 , pp. 348-363
    • Akimova, T.1    Ge, G.2    Golovina, T.3    Mikheeva, T.4    Wang, L.5
  • 30
    • 0029919434 scopus 로고    scopus 로고
    • Nicotinamide's effects on glucose metabolism in subjects at risk for IDDM
    • Greenbaum CJ, Kahn SE, Palmer JP, (1996) Nicotinamide's effects on glucose metabolism in subjects at risk for IDDM. Diabetes 45: 1631-1634.
    • (1996) Diabetes , vol.45 , pp. 1631-1634
    • Greenbaum, C.J.1    Kahn, S.E.2    Palmer, J.P.3
  • 31
    • 0031860075 scopus 로고    scopus 로고
    • The Deutsche Nicotinamide Intervention Study:an attempt to prevent type 1 diabetes. DENIS Group
    • Lampeter EF, Klinghammer A, Scherbaum WA, Heinze E, Haastert B, et al. (1998) The Deutsche Nicotinamide Intervention Study:an attempt to prevent type 1 diabetes. DENIS Group. Diabetes 47: 980-984.
    • (1998) Diabetes , vol.47 , pp. 980-984
    • Lampeter, E.F.1    Klinghammer, A.2    Scherbaum, W.A.3    Heinze, E.4    Haastert, B.5
  • 32
    • 73849128602 scopus 로고
    • Effect of nicotinic acid on liver function and leukocytes
    • Hoffer A, Callbeack MJ, (1959) Effect of nicotinic acid on liver function and leukocytes. Can Med Assoc J 80: 736-737.
    • (1959) Can Med Assoc J , vol.80 , pp. 736-737
    • Hoffer, A.1    Callbeack, M.J.2
  • 33
    • 0030017473 scopus 로고    scopus 로고
    • The effect of niacinamide on osteoarthritis:a pilot study
    • Jonas WB, Rapoza CP, Blair WF, (1996) The effect of niacinamide on osteoarthritis:a pilot study. Inflamm Res 45: 330-334.
    • (1996) Inflamm Res , vol.45 , pp. 330-334
    • Jonas, W.B.1    Rapoza, C.P.2    Blair, W.F.3
  • 34
    • 2942642383 scopus 로고    scopus 로고
    • In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
    • Tang Q, Henriksen KJ, Bi M, Finger EB, Szot G, et al. (2004) In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med 199: 1455-1465.
    • (2004) J Exp Med , vol.199 , pp. 1455-1465
    • Tang, Q.1    Henriksen, K.J.2    Bi, M.3    Finger, E.B.4    Szot, G.5
  • 36
    • 3543140687 scopus 로고    scopus 로고
    • Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy
    • Ehrenstein MR, Evans JG, Singh A, Moore S, Warnes G, et al. (2004) Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy. J Exp Med 200: 277-285.
    • (2004) J Exp Med , vol.200 , pp. 277-285
    • Ehrenstein, M.R.1    Evans, J.G.2    Singh, A.3    Moore, S.4    Warnes, G.5
  • 37
    • 12144249838 scopus 로고    scopus 로고
    • Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes
    • Lindley S, Dayan CM, Bishop A, Roep BO, Peakman M, et al. (2005) Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes. Diabetes 54: 92-99.
    • (2005) Diabetes , vol.54 , pp. 92-99
    • Lindley, S.1    Dayan, C.M.2    Bishop, A.3    Roep, B.O.4    Peakman, M.5
  • 38
    • 34047174849 scopus 로고    scopus 로고
    • Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production
    • Allan SE, Crome SQ, Crellin NK, Passerini L, Steiner TS, et al. (2007) Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production. Int Immunol 19: 345-354.
    • (2007) Int Immunol , vol.19 , pp. 345-354
    • Allan, S.E.1    Crome, S.Q.2    Crellin, N.K.3    Passerini, L.4    Steiner, T.S.5
  • 39
    • 37549032709 scopus 로고    scopus 로고
    • Generation of potent and stable human CD4+ T regulatory cells by activation-independent expression of FOXP3
    • Allan SE, Alstad AN, Merindol N, Crellin NK, Amendola M, et al. (2008) Generation of potent and stable human CD4+ T regulatory cells by activation-independent expression of FOXP3. Mol Ther 16: 194-202.
    • (2008) Mol Ther , vol.16 , pp. 194-202
    • Allan, S.E.1    Alstad, A.N.2    Merindol, N.3    Crellin, N.K.4    Amendola, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.