메뉴 건너뛰기




Volumn 2, Issue 1, 2012, Pages

RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritis

Author keywords

Next generation sequencing; Rheumatoid arthritis; RNA seq; Synovial fibroblasts; Transcriptional regulation

Indexed keywords


EID: 84873451584     PISSN: None     EISSN: 20453701     Source Type: Journal    
DOI: 10.1186/2045-3701-2-43     Document Type: Article
Times cited : (42)

References (60)
  • 1
    • 0035883897 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • 10.1016/S0140-6736(01)06075-5, 11567728
    • Lee DM, Weinblatt ME. Rheumatoid arthritis. Lancet 2001, 358:903-911. 10.1016/S0140-6736(01)06075-5, 11567728.
    • (2001) Lancet , vol.358 , pp. 903-911
    • Lee, D.M.1    Weinblatt, M.E.2
  • 3
    • 73249125200 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis
    • 10.1111/j.0105-2896.2009.00859.x, 2913689, 20193003
    • Bartok B, Firestein GS. Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunol Rev 2010, 233:233-255. 10.1111/j.0105-2896.2009.00859.x, 2913689, 20193003.
    • (2010) Immunol Rev , vol.233 , pp. 233-255
    • Bartok, B.1    Firestein, G.S.2
  • 4
    • 77957196913 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • 10.1016/S0140-6736(10)60826-4, 20870100
    • Scott DL, Wolfe F, Huizinga TW. Rheumatoid arthritis. Lancet 2010, 376:1094-1108. 10.1016/S0140-6736(10)60826-4, 20870100.
    • (2010) Lancet , vol.376 , pp. 1094-1108
    • Scott, D.L.1    Wolfe, F.2    Huizinga, T.W.3
  • 5
    • 77953251575 scopus 로고    scopus 로고
    • Innate immunity and rheumatoid arthritis
    • 10.1016/j.rdc.2010.03.004, 2937347, 20510234
    • Gierut A, Perlman H, Pope RM. Innate immunity and rheumatoid arthritis. Rheum Dis Clin North Am 2010, 36:271-296. 10.1016/j.rdc.2010.03.004, 2937347, 20510234.
    • (2010) Rheum Dis Clin North Am , vol.36 , pp. 271-296
    • Gierut, A.1    Perlman, H.2    Pope, R.M.3
  • 6
    • 79955049746 scopus 로고    scopus 로고
    • Pathophysiology of rheumatoid arthritis
    • 10.1097/BOR.0b013e32834518a3, 21427580
    • Cooles FA, Isaacs JD. Pathophysiology of rheumatoid arthritis. Curr Opin Rheumatol 2011, 23:233-240. 10.1097/BOR.0b013e32834518a3, 21427580.
    • (2011) Curr Opin Rheumatol , vol.23 , pp. 233-240
    • Cooles, F.A.1    Isaacs, J.D.2
  • 7
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • 10.1038/nature01661, 12748655
    • Firestein GS. Evolving concepts of rheumatoid arthritis. Nature 2003, 423:356-361. 10.1038/nature01661, 12748655.
    • (2003) Nature , vol.423 , pp. 356-361
    • Firestein, G.S.1
  • 8
    • 79955040826 scopus 로고    scopus 로고
    • New therapies in the management of rheumatoid arthritis
    • 10.1097/BOR.0b013e3283454124, 21427579
    • Buch MH, Emery P. New therapies in the management of rheumatoid arthritis. Curr Opin Rheumatol 2011, 23:245-251. 10.1097/BOR.0b013e3283454124, 21427579.
    • (2011) Curr Opin Rheumatol , vol.23 , pp. 245-251
    • Buch, M.H.1    Emery, P.2
  • 9
    • 79959435199 scopus 로고    scopus 로고
    • Genome-wide genetic marker discovery and genotyping using next-generation sequencing
    • 10.1038/nrg3012, 21681211
    • Davey JW, Hohenlohe PA, Etter PD, Boone JQ, Catchen JM, Blaxter ML. Genome-wide genetic marker discovery and genotyping using next-generation sequencing. Nat Rev Genet 2011, 12:499-510. 10.1038/nrg3012, 21681211.
    • (2011) Nat Rev Genet , vol.12 , pp. 499-510
    • Davey, J.W.1    Hohenlohe, P.A.2    Etter, P.D.3    Boone, J.Q.4    Catchen, J.M.5    Blaxter, M.L.6
  • 10
    • 50649089207 scopus 로고    scopus 로고
    • RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays
    • 10.1101/gr.079558.108, 2527709, 18550803
    • Marioni JC, Mason CE, Mane SM, Stephens M, Gilad Y. RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays. Genome Res 2008, 18:1509-1517. 10.1101/gr.079558.108, 2527709, 18550803.
    • (2008) Genome Res , vol.18 , pp. 1509-1517
    • Marioni, J.C.1    Mason, C.E.2    Mane, S.M.3    Stephens, M.4    Gilad, Y.5
  • 11
    • 84863176523 scopus 로고    scopus 로고
    • RNA-seq reveals novel transcriptome of genes and their isoforms in human pulmonary microvascular endothelial cells treated with thrombin
    • 10.1371/journal.pone.0031229, 3281071, 22359579
    • Zhang LQ, Cheranova D, Gibson M, Ding S, Heruth DP, Fang D, Ye SQ. RNA-seq reveals novel transcriptome of genes and their isoforms in human pulmonary microvascular endothelial cells treated with thrombin. PLoS One 2012, 7:e31229. 10.1371/journal.pone.0031229, 3281071, 22359579.
    • (2012) PLoS One , vol.7
    • Zhang, L.Q.1    Cheranova, D.2    Gibson, M.3    Ding, S.4    Heruth, D.P.5    Fang, D.6    Ye, S.Q.7
  • 12
    • 84873423701 scopus 로고    scopus 로고
    • RNA-seq analysis of transcriptomes in thrombin-treated and control human pulmonary microvascular endothelial cells
    • in press
    • Cheranova DGM, Chaudhary S, Zhang LQ, Heruth DP, Grigoryev DN, Ye SQ. RNA-seq analysis of transcriptomes in thrombin-treated and control human pulmonary microvascular endothelial cells. J Vis Exp 2012, in press.
    • (2012) J Vis Exp
    • Cheranova, D.G.M.1    Chaudhary, S.2    Zhang, L.Q.3    Heruth, D.P.4    Grigoryev, D.N.5    Ye, S.Q.6
  • 13
    • 79251644774 scopus 로고    scopus 로고
    • Whole transcriptome sequencing reveals gene expression and splicing differences in brain regions affected by Alzheimer's disease
    • 10.1371/journal.pone.0016266, 3025006, 21283692
    • Twine NA, Janitz K, Wilkins MR, Janitz M. Whole transcriptome sequencing reveals gene expression and splicing differences in brain regions affected by Alzheimer's disease. PLoS One 2011, 6:e16266. 10.1371/journal.pone.0016266, 3025006, 21283692.
    • (2011) PLoS One , vol.6
    • Twine, N.A.1    Janitz, K.2    Wilkins, M.R.3    Janitz, M.4
  • 14
    • 3242784052 scopus 로고    scopus 로고
    • A review of the MHC genetics of rheumatoid arthritis
    • 10.1038/sj.gene.6364045, 14749714
    • Newton JL, Harney SM, Wordsworth BP, Brown MA. A review of the MHC genetics of rheumatoid arthritis. Genes Immun 2004, 5:151-157. 10.1038/sj.gene.6364045, 14749714.
    • (2004) Genes Immun , vol.5 , pp. 151-157
    • Newton, J.L.1    Harney, S.M.2    Wordsworth, B.P.3    Brown, M.A.4
  • 16
    • 71249135693 scopus 로고    scopus 로고
    • Conditional analysis of the major histocompatibility complex in rheumatoid arthritis
    • Taylor KE, Criswell LA. Conditional analysis of the major histocompatibility complex in rheumatoid arthritis. BMC Proc 2009, 7(3):S36.
    • (2009) BMC Proc , vol.7 , Issue.3
    • Taylor, K.E.1    Criswell, L.A.2
  • 19
    • 0031898556 scopus 로고    scopus 로고
    • Prevalence and characterization of novel pANCA, antibodies to the high mobility group non-histone chromosomal proteins HMG1 and HMG2, in systemic rheumatic diseases
    • Uesugi H, Ozaki S, Sobajima J, Osakada F, Shirakawa H, Yoshida M, Nakao K. Prevalence and characterization of novel pANCA, antibodies to the high mobility group non-histone chromosomal proteins HMG1 and HMG2, in systemic rheumatic diseases. J Rheumatol 1998, 25:703-709.
    • (1998) J Rheumatol , vol.25 , pp. 703-709
    • Uesugi, H.1    Ozaki, S.2    Sobajima, J.3    Osakada, F.4    Shirakawa, H.5    Yoshida, M.6    Nakao, K.7
  • 20
    • 34547688939 scopus 로고    scopus 로고
    • Constitutive upregulation of the transforming growth factor-beta pathway in rheumatoid arthritis synovial fibroblasts
    • 10.1186/ar2217, 2206335, 17594488
    • Pohlers D, Beyer A, Koczan D, Wilhelm T, Thiesen HJ, Kinne RW. Constitutive upregulation of the transforming growth factor-beta pathway in rheumatoid arthritis synovial fibroblasts. Arthritis Res Ther 2007, 9:R59. 10.1186/ar2217, 2206335, 17594488.
    • (2007) Arthritis Res Ther , vol.9
    • Pohlers, D.1    Beyer, A.2    Koczan, D.3    Wilhelm, T.4    Thiesen, H.J.5    Kinne, R.W.6
  • 21
    • 4444260122 scopus 로고    scopus 로고
    • Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis
    • 10.1002/art.20478, 15457473
    • Williams AS, Mizuno M, Richards PJ, Holt DS, Morgan BP. Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis. Arthritis Rheum 2004, 50:3035-3044. 10.1002/art.20478, 15457473.
    • (2004) Arthritis Rheum , vol.50 , pp. 3035-3044
    • Williams, A.S.1    Mizuno, M.2    Richards, P.J.3    Holt, D.S.4    Morgan, B.P.5
  • 24
    • 84859495958 scopus 로고    scopus 로고
    • CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates beta-cleavage of beta-amyloid precursor protein (APP) through interacting with beta-site APP cleaving protein 1 (BACE1)
    • 10.1074/jbc.M111.330209, 22351782
    • Zhao Y, Wang Y, Hu J, Zhang X, Zhang YW. CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates beta-cleavage of beta-amyloid precursor protein (APP) through interacting with beta-site APP cleaving protein 1 (BACE1). J Biol Chem 2012, 287:11141-11150. 10.1074/jbc.M111.330209, 22351782.
    • (2012) J Biol Chem , vol.287 , pp. 11141-11150
    • Zhao, Y.1    Wang, Y.2    Hu, J.3    Zhang, X.4    Zhang, Y.W.5
  • 26
    • 77955711839 scopus 로고    scopus 로고
    • Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation
    • 10.1038/cdd.2010.16, 20186153
    • Xiao L, Gong LL, Yuan D, Deng M, Zeng XM, Chen LL, Zhang L, Yan Q, Liu JP, Hu XH, et al. Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation. Cell Death Differ 2010, 17:1448-1462. 10.1038/cdd.2010.16, 20186153.
    • (2010) Cell Death Differ , vol.17 , pp. 1448-1462
    • Xiao, L.1    Gong, L.L.2    Yuan, D.3    Deng, M.4    Zeng, X.M.5    Chen, L.L.6    Zhang, L.7    Yan, Q.8    Liu, J.P.9    Hu, X.H.10
  • 27
    • 84866714220 scopus 로고    scopus 로고
    • IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation
    • 10.1371/journal.pbio.1001395, 3463509, 23055831
    • Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, Hoppe E, Barré B, Audran M, Bouvard B, et al. IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. PLoS Biol 2012, 10:e1001395. 10.1371/journal.pbio.1001395, 3463509, 23055831.
    • (2012) PLoS Biol , vol.10
    • Corvaisier, M.1    Delneste, Y.2    Jeanvoine, H.3    Preisser, L.4    Blanchard, S.5    Garo, E.6    Hoppe, E.7    Barré, B.8    Audran, M.9    Bouvard, B.10
  • 28
    • 55049089081 scopus 로고    scopus 로고
    • Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis
    • Liu C, Batliwalla F, Li W, Lee A, Roubenoff R, Beckman E, Khalili H, Damle A, Kern M, Furie R, et al. Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis. Mol med (Cambridge, Mass) 2008, 14:575-581.
    • (2008) Mol med (Cambridge, Mass) , vol.14 , pp. 575-581
    • Liu, C.1    Batliwalla, F.2    Li, W.3    Lee, A.4    Roubenoff, R.5    Beckman, E.6    Khalili, H.7    Damle, A.8    Kern, M.9    Furie, R.10
  • 29
    • 0034745026 scopus 로고    scopus 로고
    • Molecular mechanisms for alpha2-adrenoceptor-mediated regulation of synoviocyte populations
    • 10.1254/jjp.85.214, 11325013
    • Mishima K, Otani H, Tanabe T, Kawasaki H, Oshiro A, Saito N, Ogawa R, Inagaki C. Molecular mechanisms for alpha2-adrenoceptor-mediated regulation of synoviocyte populations. Jpn J Pharmacol 2001, 85:214-226. 10.1254/jjp.85.214, 11325013.
    • (2001) Jpn J Pharmacol , vol.85 , pp. 214-226
    • Mishima, K.1    Otani, H.2    Tanabe, T.3    Kawasaki, H.4    Oshiro, A.5    Saito, N.6    Ogawa, R.7    Inagaki, C.8
  • 30
    • 77952924625 scopus 로고    scopus 로고
    • The axis of thrombospondin-1, transforming growth factor beta and connective tissue growth factor: an emerging therapeutic target in rheumatoid arthritis
    • 10.2174/157016110791112296, 19485899
    • Rico MC, Rough JJ, Del Carpio-Cano FE, Kunapuli SP, DeLa Cadena RA. The axis of thrombospondin-1, transforming growth factor beta and connective tissue growth factor: an emerging therapeutic target in rheumatoid arthritis. Curr Vasc Pharmacol 2010, 8:338-343. 10.2174/157016110791112296, 19485899.
    • (2010) Curr Vasc Pharmacol , vol.8 , pp. 338-343
    • Rico, M.C.1    Rough, J.J.2    Del Carpio-Cano, F.E.3    Kunapuli, S.P.4    DeLa Cadena, R.A.5
  • 32
    • 84866033089 scopus 로고    scopus 로고
    • Interactions of the complement system with molecules of extracellular matrix: relevance for joint diseases
    • 10.1016/j.imbio.2012.07.013, 22964234
    • Happonen KE, Heinegard D, Saxne T, Blom AM. Interactions of the complement system with molecules of extracellular matrix: relevance for joint diseases. Immunobiology 2012, 217:1088-1096. 10.1016/j.imbio.2012.07.013, 22964234.
    • (2012) Immunobiology , vol.217 , pp. 1088-1096
    • Happonen, K.E.1    Heinegard, D.2    Saxne, T.3    Blom, A.M.4
  • 33
    • 0030805452 scopus 로고    scopus 로고
    • Plasminogen activation in synovial tissues: differences between normal, osteoarthritis, and rheumatoid arthritis joints
    • 10.1136/ard.56.9.550, 1752434, 9370880
    • Busso N, Peclat V, So A, Sappino AP. Plasminogen activation in synovial tissues: differences between normal, osteoarthritis, and rheumatoid arthritis joints. Ann Rheum Dis 1997, 56:550-557. 10.1136/ard.56.9.550, 1752434, 9370880.
    • (1997) Ann Rheum Dis , vol.56 , pp. 550-557
    • Busso, N.1    Peclat, V.2    So, A.3    Sappino, A.P.4
  • 35
    • 43049113102 scopus 로고    scopus 로고
    • Coagulation signalling following tissue injury: focus on the role of factor Xa
    • 10.1016/j.biocel.2008.02.026, 18420447
    • Krupiczojc MA, Scotton CJ, Chambers RC. Coagulation signalling following tissue injury: focus on the role of factor Xa. Int J Biochem Cell Biol 2008, 40:1228-1237. 10.1016/j.biocel.2008.02.026, 18420447.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 1228-1237
    • Krupiczojc, M.A.1    Scotton, C.J.2    Chambers, R.C.3
  • 37
    • 33744760210 scopus 로고    scopus 로고
    • Coexistent Marfan's syndrome and ankylosing spondylitis
    • Kiss C, Jonap I, Gergely P, Poor G. Coexistent Marfan's syndrome and ankylosing spondylitis. J Rheumatol 2006, 33:1199-1200.
    • (2006) J Rheumatol , vol.33 , pp. 1199-1200
    • Kiss, C.1    Jonap, I.2    Gergely, P.3    Poor, G.4
  • 38
    • 17244370023 scopus 로고    scopus 로고
    • Reduced p53 in peripheral blood mononuclear cells from patients with rheumatoid arthritis is associated with loss of radiation-induced apoptosis
    • 10.1002/art.20931, 15818671
    • Maas K, Westfall M, Pietenpol J, Olsen NJ, Aune T. Reduced p53 in peripheral blood mononuclear cells from patients with rheumatoid arthritis is associated with loss of radiation-induced apoptosis. Arthritis Rheum 2005, 52:1047-1057. 10.1002/art.20931, 15818671.
    • (2005) Arthritis Rheum , vol.52 , pp. 1047-1057
    • Maas, K.1    Westfall, M.2    Pietenpol, J.3    Olsen, N.J.4    Aune, T.5
  • 40
    • 46249106990 scopus 로고    scopus 로고
    • Mapping and quantifying mammalian transcriptomes by RNA-Seq
    • 10.1038/nmeth.1226, 18516045
    • Mortazavi A, Williams BA, McCue K, Schaeffer L, Wold B. Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods 2008, 5:621-628. 10.1038/nmeth.1226, 18516045.
    • (2008) Nat Methods , vol.5 , pp. 621-628
    • Mortazavi, A.1    Williams, B.A.2    McCue, K.3    Schaeffer, L.4    Wold, B.5
  • 41
    • 34548448091 scopus 로고    scopus 로고
    • Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity
    • 10.1038/sj.gene.6364400, 17568789
    • Galligan CL, Baig E, Bykerk V, Keystone EC, Fish EN. Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity. Genes Immun 2007, 8:480-491. 10.1038/sj.gene.6364400, 17568789.
    • (2007) Genes Immun , vol.8 , pp. 480-491
    • Galligan, C.L.1    Baig, E.2    Bykerk, V.3    Keystone, E.C.4    Fish, E.N.5
  • 42
    • 84855358855 scopus 로고    scopus 로고
    • Transcriptome analysis reveals specific changes in osteoarthritis synovial fibroblasts
    • 10.1136/annrheumdis-2011-200281, 22021863
    • Del Rey MJ, Usategui A, Izquierdo E, Canete JD, Blanco FJ, Criado G, Pablos JL. Transcriptome analysis reveals specific changes in osteoarthritis synovial fibroblasts. Ann Rheum Dis 2012, 71:275-280. 10.1136/annrheumdis-2011-200281, 22021863.
    • (2012) Ann Rheum Dis , vol.71 , pp. 275-280
    • Del Rey, M.J.1    Usategui, A.2    Izquierdo, E.3    Canete, J.D.4    Blanco, F.J.5    Criado, G.6    Pablos, J.L.7
  • 43
    • 78650045543 scopus 로고    scopus 로고
    • The transcriptional response of normal and rheumatoid arthritis synovial fibroblasts to hypoxia
    • 10.1002/art.27750, 20848564
    • Del Rey MJ, Izquierdo E, Usategui A, Gonzalo E, Blanco FJ, Acquadro F, Pablos JL. The transcriptional response of normal and rheumatoid arthritis synovial fibroblasts to hypoxia. Arthritis Rheum 2010, 62:3584-3594. 10.1002/art.27750, 20848564.
    • (2010) Arthritis Rheum , vol.62 , pp. 3584-3594
    • Del Rey, M.J.1    Izquierdo, E.2    Usategui, A.3    Gonzalo, E.4    Blanco, F.J.5    Acquadro, F.6    Pablos, J.L.7
  • 44
    • 0036289709 scopus 로고    scopus 로고
    • Gene expression profile analysis of rheumatoid synovial fibroblast cultures revealing the overexpression of genes responsible for tumor-like growth of rheumatoid synovium
    • 10.1016/S0006-291X(02)00608-3, 12074593
    • Watanabe N, Ando K, Yoshida S, Inuzuka S, Kobayashi M, Matsui N, Okamoto T. Gene expression profile analysis of rheumatoid synovial fibroblast cultures revealing the overexpression of genes responsible for tumor-like growth of rheumatoid synovium. Biochem Biophys Res Commun 2002, 294:1121-1129. 10.1016/S0006-291X(02)00608-3, 12074593.
    • (2002) Biochem Biophys Res Commun , vol.294 , pp. 1121-1129
    • Watanabe, N.1    Ando, K.2    Yoshida, S.3    Inuzuka, S.4    Kobayashi, M.5    Matsui, N.6    Okamoto, T.7
  • 46
    • 0038151908 scopus 로고    scopus 로고
    • Discovery of distinctive gene expression profiles in rheumatoid synovium using cDNA microarray technology: evidence for the existence of multiple pathways of tissue destruction and repair
    • 10.1038/sj.gene.6363975, 12700593
    • Van Der Pouw Kraan TC, van Gaalen FA, Huizinga TW, Pieterman E, Breedveld FC, Verweij CL. Discovery of distinctive gene expression profiles in rheumatoid synovium using cDNA microarray technology: evidence for the existence of multiple pathways of tissue destruction and repair. Genes Immun 2003, 4:187-196. 10.1038/sj.gene.6363975, 12700593.
    • (2003) Genes Immun , vol.4 , pp. 187-196
    • Van Der Pouw Kraan, T.C.1    van Gaalen, F.A.2    Huizinga, T.W.3    Pieterman, E.4    Breedveld, F.C.5    Verweij, C.L.6
  • 47
    • 34247591787 scopus 로고    scopus 로고
    • Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation
    • 10.1186/ar427, 125298, 12223111
    • Masuda K, Masuda R, Neidhart M, Simmen BR, Michel BA, Muller-Ladner U, Gay RE, Gay S. Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation. Arthritis Res 2002, 4:R8. 10.1186/ar427, 125298, 12223111.
    • (2002) Arthritis Res , vol.4
    • Masuda, K.1    Masuda, R.2    Neidhart, M.3    Simmen, B.R.4    Michel, B.A.5    Muller-Ladner, U.6    Gay, R.E.7    Gay, S.8
  • 48
    • 34047144393 scopus 로고    scopus 로고
    • Gene expression profiling of rheumatoid arthritis synovial cells treated with antirheumatic drugs
    • 10.1177/1087057107299261, 17379860
    • Haupl T, Yahyawi M, Lubke C, Ringe J, Rohrlach T, Burmester GR, Sittinger M, Kaps C. Gene expression profiling of rheumatoid arthritis synovial cells treated with antirheumatic drugs. J Biomol Screen 2007, 12:328-340. 10.1177/1087057107299261, 17379860.
    • (2007) J Biomol Screen , vol.12 , pp. 328-340
    • Haupl, T.1    Yahyawi, M.2    Lubke, C.3    Ringe, J.4    Rohrlach, T.5    Burmester, G.R.6    Sittinger, M.7    Kaps, C.8
  • 51
    • 84863237736 scopus 로고    scopus 로고
    • Decoding the differential biomarkers of Rheumatoid arthritis and Osteoarthritis: a functional genomics paradigm to design disease specific therapeutics
    • 10.6026/97320630006153, 3092949, 21572882
    • Biswas S, Manikandan J, Pushparaj PN. Decoding the differential biomarkers of Rheumatoid arthritis and Osteoarthritis: a functional genomics paradigm to design disease specific therapeutics. Bioinformation 2011, 6:153-157. 10.6026/97320630006153, 3092949, 21572882.
    • (2011) Bioinformation , vol.6 , pp. 153-157
    • Biswas, S.1    Manikandan, J.2    Pushparaj, P.N.3
  • 53
    • 40949123747 scopus 로고    scopus 로고
    • TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes
    • Yarilina A, Park-Min KH, Antoniv T, Hu X, Ivashkiv LB. TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon-response genes. Nat Immunol 2008, 9:378-387.
    • (2008) Nat Immunol , vol.9 , pp. 378-387
    • Yarilina, A.1    Park-Min, K.H.2    Antoniv, T.3    Hu, X.4    Ivashkiv, L.B.5
  • 54
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-seq
    • 10.1093/bioinformatics/btp120, 2672628, 19289445
    • Trapnell C, Pachter L, Salzberg SL. TopHat: discovering splice junctions with RNA-seq. Bioinformatics 2009, 25:1105-1111. 10.1093/bioinformatics/btp120, 2672628, 19289445.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 56
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • 10.1186/gb-2009-10-3-r25, 2690996, 19261174
    • Langmead B, Trapnell C, Pop M, Salzberg SL. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 2009, 10:R25. 10.1186/gb-2009-10-3-r25, 2690996, 19261174.
    • (2009) Genome Biol , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 57
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • 10.1038/nbt.1621, 3146043, 20436464
    • Trapnell C, Williams BA, Pertea G, Mortazavi A, Kwan G, van Baren MJ, Salzberg SL, Wold BJ, Pachter L. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 2010, 28:511-515. 10.1038/nbt.1621, 3146043, 20436464.
    • (2010) Nat Biotechnol , vol.28 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3    Mortazavi, A.4    Kwan, G.5    van Baren, M.J.6    Salzberg, S.L.7    Wold, B.J.8    Pachter, L.9
  • 58
    • 77951770756 scopus 로고    scopus 로고
    • BEDTools: a flexible suite of utilities for comparing genomic features
    • 10.1093/bioinformatics/btq033, 2832824, 20110278
    • Quinlan AR, Hall IM. BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics 2010, 26:841-842. 10.1093/bioinformatics/btq033, 2832824, 20110278.
    • (2010) Bioinformatics , vol.26 , pp. 841-842
    • Quinlan, A.R.1    Hall, I.M.2
  • 60
    • 4644262045 scopus 로고    scopus 로고
    • Orthologous gene-expression profiling in multi-species models: search for candidate genes
    • 10.1186/gb-2004-5-5-r34, 416470, 15128448
    • Grigoryev DN, Ma SF, Irizarry RA, Ye SQ, Quackenbush J, Garcia JG. Orthologous gene-expression profiling in multi-species models: search for candidate genes. Genome Biol 2004, 5:R34. 10.1186/gb-2004-5-5-r34, 416470, 15128448.
    • (2004) Genome Biol , vol.5
    • Grigoryev, D.N.1    Ma, S.F.2    Irizarry, R.A.3    Ye, S.Q.4    Quackenbush, J.5    Garcia, J.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.