-
1
-
-
26244462712
-
Thymic regulatory T cells
-
Maggi, E., L. Cosmi, F. Liotta, P. Romagnani, S. Romagnani, and F. Annunziato. 2005. Thymic regulatory T cells. Autoimmun. Rev. 4: 579-586.
-
(2005)
Autoimmun. Rev
, vol.4
, pp. 579-586
-
-
Maggi, E.1
Cosmi, L.2
Liotta, F.3
Romagnani, P.4
Romagnani, S.5
Annunziato, F.6
-
2
-
-
16844365788
-
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
-
Sakaguchi, S. 2005. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat. Immunol. 6: 345-352.
-
(2005)
Nat. Immunol
, vol.6
, pp. 345-352
-
-
Sakaguchi, S.1
-
3
-
-
84865483192
-
Administration of CD4+CD25highCD127- regulatory T cells preserves b-cell function in type 1 diabetes in children
-
Marek-Trzonkowska, N., M. Mysliwiec, A. Dobyszuk, M. Grabowska, I. Techmanska, J. Juscinska, M. A. Wujtewicz, P. Witkowski, W. Mlynarski, A. Balcerska, et al. 2012. Administration of CD4+CD25highCD127- regulatory T cells preserves b-cell function in type 1 diabetes in children. Diabetes Care 35: 1817-1820.
-
(2012)
Diabetes Care
, vol.35
, pp. 1817-1820
-
-
Marek-Trzonkowska, N.1
Mysliwiec, M.2
Dobyszuk, A.3
Grabowska, M.4
Techmanska, I.5
Juscinska, J.6
Wujtewicz, M.A.7
Witkowski, P.8
Mlynarski, W.9
Balcerska, A.10
-
4
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
Tang, Q., K. J. Henriksen, M. Bi, E. B. Finger, G. Szot, J. Ye, E. L. Masteller, H. McDevitt, M. Bonyhadi, and J. A. Bluestone. 2004. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J. Exp. Med. 199: 1455-1465.
-
(2004)
J. Exp. Med
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
Finger, E.B.4
Szot, G.5
Ye, J.6
Masteller, E.L.7
McDevitt, H.8
Bonyhadi, M.9
Bluestone, J.A.10
-
5
-
-
33846410255
-
Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
-
Tarbell, K. V., L. Petit, X. Zuo, P. Toy, X. Luo, A. Mqadmi, H. Yang, M. Suthanthiran, S. Mojsov, and R. M. Steinman. 2007. Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice. J. Exp. Med. 204: 191-201.
-
(2007)
J. Exp. Med
, vol.204
, pp. 191-201
-
-
Tarbell, K.V.1
Petit, L.2
Zuo, X.3
Toy, P.4
Luo, X.5
Mqadmi, A.6
Yang, H.7
Suthanthiran, M.8
Mojsov, S.9
Steinman, R.M.10
-
6
-
-
70249122695
-
First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells
-
Trzonkowski, P., M. Bieniaszewska, J. Jus̈cińska, A. Dobyszuk, A. Krzystyniak, N. Marek, J. Mys̈liwska, and A. Hellmann. 2009. First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells. Clin. Immunol. 133: 22-26.
-
(2009)
Clin. Immunol
, vol.133
, pp. 22-26
-
-
Trzonkowski, P.1
Bieniaszewska, M.2
Jus̈cińska, J.3
Dobyszuk, A.4
Krzystyniak, A.5
Marek, N.6
Mys̈liwska, J.7
Hellmann, A.8
-
7
-
-
78751696183
-
Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics
-
Brunstein, C. G., J. S. Miller, Q. Cao, D. H. McKenna, K. L. Hippen, J. Curtsinger, T. Defor, B. L. Levine, C. H. June, P. Rubinstein, et al. 2011. Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics. Blood 117: 1061-1070.
-
(2011)
Blood
, vol.117
, pp. 1061-1070
-
-
Brunstein, C.G.1
Miller, J.S.2
Cao, Q.3
McKenna, D.H.4
Hippen, K.L.5
Curtsinger, J.6
Defor, T.7
Levine, B.L.8
June, C.H.9
Rubinstein, P.10
-
8
-
-
79953809817
-
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
-
Di Ianni, M., F. Falzetti, A. Carotti, A. Terenzi, F. Castellino, E. Bonifacio, B. Del Papa, T. Zei, R. I. Ostini, D. Cecchini, et al. 2011. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood 117: 3921-3928.
-
(2011)
Blood
, vol.117
, pp. 3921-3928
-
-
Di Ianni, M.1
Falzetti, F.2
Carotti, A.3
Terenzi, A.4
Castellino, F.5
Bonifacio, E.6
Del Papa, B.7
Zei, T.8
Ostini, R.I.9
Cecchini, D.10
-
9
-
-
79956288367
-
Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells
-
Sagoo, P., N. Ali, G. Garg, F. O. Nestle, R. I. Lechler, and G. Lombardi. 2011. Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells. Sci. Transl. Med. 3: 83ra42.
-
(2011)
Sci. Transl. Med
, vol.3
, pp. 83ra42
-
-
Sagoo, P.1
Ali, N.2
Garg, G.3
Nestle, F.O.4
Lechler, R.I.5
Lombardi, G.6
-
10
-
-
84886786872
-
Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation
-
Putnam, A. L., N. Safinia, A. Medvec, M. Laszkowska, M. Wray, M. A. Mintz, E. Trotta, G. L. Szot, W. Liu, A. Lares, et al. 2013. Clinical grade manufacturing of human alloantigen-reactive regulatory T cells for use in transplantation. Am. J. Transplant. 13: 3010-3020.
-
(2013)
Am. J. Transplant
, vol.13
, pp. 3010-3020
-
-
Putnam, A.L.1
Safinia, N.2
Medvec, A.3
Laszkowska, M.4
Wray, M.5
Mintz, M.A.6
Trotta, E.7
Szot, G.L.8
Liu, W.9
Lares, A.10
-
11
-
-
84856578856
-
Identification of circulating human antigen-reactive CD4+ FOXP3+ natural regulatory T cells
-
Litjens, N. H., K. Boer, and M. G. Betjes. 2012. Identification of circulating human antigen-reactive CD4+ FOXP3+ natural regulatory T cells. J. Immunol. 188: 1083-1090.
-
(2012)
J. Immunol
, vol.188
, pp. 1083-1090
-
-
Litjens, N.H.1
Boer, K.2
Betjes, M.G.3
-
12
-
-
33244455884
-
Isolation of CD4+CD25+ regulatory T cells for clinical trials
-
Hoffmann, P., T. J. Boeld, R. Eder, J. Albrecht, K. Doser, B. Piseshka, A. Dada, C. Niemand, M. Assenmacher, E. Orsó, et al. 2006. Isolation of CD4+CD25+ regulatory T cells for clinical trials. Biol. Blood Marrow Transplant. 12: 267-274.
-
(2006)
Biol. Blood Marrow Transplant
, vol.12
, pp. 267-274
-
-
Hoffmann, P.1
Boeld, T.J.2
Eder, R.3
Albrecht, J.4
Doser, K.5
Piseshka, B.6
Dada, A.7
Niemand, C.8
Assenmacher, M.9
Orsó, E.10
-
13
-
-
33748936649
-
Efficient and reproducible large-scale isolation of human CD4+ CD25+ regulatory T cells with potent suppressor activity
-
Wichlan, D. G., P. L. Roddam, P. Eldridge, R. Handgretinger, and J. M. Riberdy. 2006. Efficient and reproducible large-scale isolation of human CD4+ CD25+ regulatory T cells with potent suppressor activity. J. Immunol. Methods 315: 27-36.
-
(2006)
J. Immunol. Methods
, vol.315
, pp. 27-36
-
-
Wichlan, D.G.1
Roddam, P.L.2
Eldridge, P.3
Handgretinger, R.4
Riberdy, J.M.5
-
14
-
-
18144396195
-
In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation
-
Earle, K. E., Q. Tang, X. Zhou, W. Liu, S. Zhu, M. L. Bonyhadi, and J. A. Bluestone. 2005. In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation. Clin. Immunol. 115: 3-9.
-
(2005)
Clin. Immunol
, vol.115
, pp. 3-9
-
-
Earle, K.E.1
Tang, Q.2
Zhou, X.3
Liu, W.4
Zhu, S.5
Bonyhadi, M.L.6
Bluestone, J.A.7
-
15
-
-
79952199736
-
Polyclonal expansion of human CD4(+)CD25(+) regulatory T cells
-
Hoffmann, P., R. Eder, and M. Edinger. 2011. Polyclonal expansion of human CD4(+)CD25(+) regulatory T cells. Methods Mol. Biol. 677: 15-30.
-
(2011)
Methods Mol. Biol
, vol.677
, pp. 15-30
-
-
Hoffmann, P.1
Eder, R.2
Edinger, M.3
-
16
-
-
33845379986
-
Rapamycin promotes expansion of functional CD4+ CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients
-
Battaglia, M., A. Stabilini, B. Migliavacca, J. Horejs-Hoeck, T. Kaupper, and M. G. Roncarolo. 2006. Rapamycin promotes expansion of functional CD4+ CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients. J. Immunol. 177: 8338-8347.
-
(2006)
J. Immunol
, vol.177
, pp. 8338-8347
-
-
Battaglia, M.1
Stabilini, A.2
Migliavacca, B.3
Horejs-Hoeck, J.4
Kaupper, T.5
Roncarolo, M.G.6
-
17
-
-
20444373376
-
Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells
-
Battaglia, M., A. Stabilini, and M. G. Roncarolo. 2005. Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. Blood 105: 4743-4748.
-
(2005)
Blood
, vol.105
, pp. 4743-4748
-
-
Battaglia, M.1
Stabilini, A.2
Roncarolo, M.G.3
-
18
-
-
48249098901
-
Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25 (high) T cells for immunotherapy
-
Peters, J. H., L. B. Hilbrands, H. J. Koenen, and I. Joosten. 2008. Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25 (high) T cells for immunotherapy. PLoS ONE 3: e2233.
-
(2008)
PLoS ONE
, vol.3
-
-
Peters, J.H.1
Hilbrands, L.B.2
Koenen, H.J.3
Joosten, I.4
-
19
-
-
81555214616
-
Ex vivo expansion of human Tregs specific for alloantigens presented directly or indirectly
-
Veerapathran, A., J. Pidala, F. Beato, X. Z. Yu, and C. Anasetti. 2011. Ex vivo expansion of human Tregs specific for alloantigens presented directly or indirectly. Blood 118: 5671-5680.
-
(2011)
Blood
, vol.118
, pp. 5671-5680
-
-
Veerapathran, A.1
Pidala, J.2
Beato, F.3
Yu, X.Z.4
Anasetti, C.5
-
20
-
-
70349336184
-
Direct expansion of human allospecific FoxP3+CD4+ regulatory T cells with allogeneic B cells for therapeutic application
-
Chen, L. C., J. C. Delgado, P. E. Jensen, and X. Chen. 2009. Direct expansion of human allospecific FoxP3+CD4+ regulatory T cells with allogeneic B cells for therapeutic application. J. Immunol. 183: 4094-4102.
-
(2009)
J. Immunol
, vol.183
, pp. 4094-4102
-
-
Chen, L.C.1
Delgado, J.C.2
Jensen, P.E.3
Chen, X.4
-
21
-
-
79958224706
-
Requirements for prolongation of allograft survival with regulatory T cell infusion in lymphosufficient hosts
-
Brennan, T. V., Q. Tang, F. C. Liu, V. Hoang, M. Bi, J. A. Bluestone, and S. M. Kang. 2011. Requirements for prolongation of allograft survival with regulatory T cell infusion in lymphosufficient hosts. J. Surg. Res. 169: e69-e75.
-
(2011)
J. Surg. Res
, vol.169
, pp. e69-e75
-
-
Brennan, T.V.1
Tang, Q.2
Liu, F.C.3
Hoang, V.4
Bi, M.5
Bluestone, J.A.6
Kang, S.M.7
-
22
-
-
33846214275
-
In vitro-expanded donor alloantigen-specific CD4+CD25+ regulatory T cells promote experimental transplantation tolerance
-
Golshayan, D., S. Jiang, J. Tsang, M. I. Garin, C. Mottet, and R. I. Lechler. 2007. In vitro-expanded donor alloantigen-specific CD4+CD25+ regulatory T cells promote experimental transplantation tolerance. Blood 109: 827-835.
-
(2007)
Blood
, vol.109
, pp. 827-835
-
-
Golshayan, D.1
Jiang, S.2
Tsang, J.3
Garin, M.I.4
Mottet, C.5
Lechler, R.I.6
-
23
-
-
38049020656
-
Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes
-
Joffre, O., T. Santolaria, D. Calise, T. Al Saati, D. Hudrisier, P. Romagnoli, and J. P. van Meerwijk. 2008. Prevention of acute and chronic allograft rejection with CD4+CD25+Foxp3+ regulatory T lymphocytes. Nat. Med. 14: 88-92.
-
(2008)
Nat. Med
, vol.14
, pp. 88-92
-
-
Joffre, O.1
Santolaria, T.2
Calise, D.3
Al Saati, T.4
Hudrisier, D.5
Romagnoli, P.6
Van Meerwijk, J.P.7
-
24
-
-
77954539326
-
In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells
-
Nadig, S. N., J. Wieckiewicz, D. C. Wu, G. Warnecke, W. Zhang, S. Luo, A. Schiopu, D. P. Taggart, and K. J. Wood. 2010. In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells. Nat. Med. 16: 809-813.
-
(2010)
Nat. Med
, vol.16
, pp. 809-813
-
-
Nadig, S.N.1
Wieckiewicz, J.2
Wu, D.C.3
Warnecke, G.4
Zhang, W.5
Luo, S.6
Schiopu, A.7
Taggart, D.P.8
Wood, K.J.9
-
25
-
-
0346690399
-
Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
-
Trenado, A., F. Charlotte, S. Fisson, M. Yagello, D. Klatzmann, B. L. Salomon, and J. L. Cohen. 2003. Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia. J. Clin. Invest. 112: 1688-1696.
-
(2003)
J. Clin. Invest
, vol.112
, pp. 1688-1696
-
-
Trenado, A.1
Charlotte, F.2
Fisson, S.3
Yagello, M.4
Klatzmann, D.5
Salomon, B.L.6
Cohen, J.L.7
-
26
-
-
55849142632
-
Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice
-
Tsang, J. Y., Y. Tanriver, S. Jiang, S. A. Xue, K. Ratnasothy, D. Chen, H. J. Stauss, R. P. Bucy, G. Lombardi, and R. Lechler. 2008. Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice. J. Clin. Invest. 118: 3619-3628.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 3619-3628
-
-
Tsang, J.Y.1
Tanriver, Y.2
Jiang, S.3
Xue, S.A.4
Ratnasothy, K.5
Chen, D.6
Stauss, H.J.7
Bucy, R.P.8
Lombardi, G.9
Lechler, R.10
-
27
-
-
0042512461
-
Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells
-
Yamazaki, S., T. Iyoda, K. Tarbell, K. Olson, K. Velinzon, K. Inaba, and R. M. Steinman. 2003. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198: 235-247.
-
(2003)
J. Exp. Med
, vol.198
, pp. 235-247
-
-
Yamazaki, S.1
Iyoda, T.2
Tarbell, K.3
Olson, K.4
Velinzon, K.5
Inaba, K.6
Steinman, R.M.7
-
28
-
-
32644461186
-
Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction
-
Yamazaki, S., M. Patel, A. Harper, A. Bonito, H. Fukuyama, M. Pack, K. V. Tarbell, M. Talmor, J. V. Ravetch, K. Inaba, and R. M. Steinman. 2006. Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction. Proc. Natl. Acad. Sci. USA 103: 2758-2763.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 2758-2763
-
-
Yamazaki, S.1
Patel, M.2
Harper, A.3
Bonito, A.4
Fukuyama, H.5
Pack, M.6
Tarbell, K.V.7
Talmor, M.8
Ravetch, J.V.9
Inaba, K.10
Steinman, R.M.11
-
29
-
-
10844252294
-
Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells
-
Fehérvári, Z., and S. Sakaguchi. 2004. Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells. Int. Immunol. 16: 1769-1780.
-
(2004)
Int. Immunol
, vol.16
, pp. 1769-1780
-
-
Fehérvári, Z.1
Sakaguchi, S.2
-
30
-
-
84874038489
-
Therapeutic potential of semi-mature dendritic cells for tolerance induction
-
Lutz, M. B. 2012. Therapeutic potential of semi-mature dendritic cells for tolerance induction. Front. Immunol. 3: 123.
-
(2012)
Front. Immunol
, vol.3
, pp. 123
-
-
Lutz, M.B.1
-
31
-
-
80051789004
-
IL-15 and dendritic cells induce proliferation of CD4+CD25+ regulatory T cells from peripheral blood
-
Xu, S., Z. Sun, Y. Sun, J. Zhu, X. Li, X. Zhang, G. Shan, Z. Wang, H. Liu, and X. Wu. 2011. IL-15 and dendritic cells induce proliferation of CD4+CD25+ regulatory T cells from peripheral blood. Immunol. Lett. 140: 59-67.
-
(2011)
Immunol. Lett
, vol.140
, pp. 59-67
-
-
Xu, S.1
Sun, Z.2
Sun, Y.3
Zhu, J.4
Li, X.5
Zhang, X.6
Shan, G.7
Wang, Z.8
Liu, H.9
Wu, X.10
-
32
-
-
70449730679
-
The human alloreactive CD4+ T-cell repertoire is biased to a Th17 response and the frequency is inversely related to the number of HLA class II mismatches
-
Litjens, N. H., J. van de Wetering, N. M. van Besouw, and M. G. Betjes. 2009. The human alloreactive CD4+ T-cell repertoire is biased to a Th17 response and the frequency is inversely related to the number of HLA class II mismatches. Blood 114: 3947-3955.
-
(2009)
Blood
, vol.114
, pp. 3947-3955
-
-
Litjens, N.H.1
Wetering De J.Van2
Van Besouw, N.M.3
Betjes, M.G.4
-
33
-
-
38349171278
-
Hepatitis B vaccine-specific CD4(+) T cells can be detected and characterised at the single cell level: Limited usefulness of dendritic cells as signal enhancers
-
Litjens, N. H., M. Huisman, C. C. Baan, C. J. van Druningen, and M. G. Betjes. 2008. Hepatitis B vaccine-specific CD4(+) T cells can be detected and characterised at the single cell level: limited usefulness of dendritic cells as signal enhancers. J. Immunol. Methods 330: 1-11.
-
(2008)
J. Immunol. Methods
, vol.330
, pp. 1-11
-
-
Litjens, N.H.1
Huisman, M.2
Baan, C.C.3
Van Druningen, C.J.4
Betjes, M.G.5
-
34
-
-
0032546352
-
Dendritic cells and the control of immunity
-
Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252.
-
(1998)
Nature
, vol.392
, pp. 245-252
-
-
Banchereau, J.1
Steinman, R.M.2
-
35
-
-
33744918280
-
A postmigrational switch among skin-derived dendritic cells to a macrophage-like phenotype is predetermined by the intracutaneous cytokine balance
-
de Gruijl, T. D., C. C. Sombroek, S. M. Lougheed, D. Oosterhoff, J. Buter, A. J. van den Eertwegh, R. J. Scheper, and H. M. Pinedo. 2006. A postmigrational switch among skin-derived dendritic cells to a macrophage-like phenotype is predetermined by the intracutaneous cytokine balance. J. Immunol. 176: 7232-7242.
-
(2006)
J. Immunol
, vol.176
, pp. 7232-7242
-
-
De Gruijl, T.D.1
Sombroek, C.C.2
Lougheed, S.M.3
Oosterhoff, D.4
Buter, J.5
Eertwegh Den Van, A.J.6
Scheper, R.J.7
Pinedo, H.M.8
-
36
-
-
14644396156
-
Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro
-
Game, D. S., M. P. Hernandez-Fuentes, and R. I. Lechler. 2005. Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro. Am. J. Transplant. 5: 454-464.
-
(2005)
Am. J. Transplant
, vol.5
, pp. 454-464
-
-
Game, D.S.1
Hernandez-Fuentes, M.P.2
Lechler, R.I.3
-
37
-
-
51549098855
-
IL-2 producing memory CD4+ T lymphocytes are closely associated with the generation of IgG-secreting plasma cells
-
Litjens, N. H., M. Huisman, D. Hijdra, B. M. Lambrecht, K. J. Stittelaar, and M. G. Betjes. 2008. IL-2 producing memory CD4+ T lymphocytes are closely associated with the generation of IgG-secreting plasma cells. J. Immunol. 181: 3665-3673.
-
(2008)
J. Immunol
, vol.181
, pp. 3665-3673
-
-
Litjens, N.H.1
Huisman, M.2
Hijdra, D.3
Lambrecht, B.M.4
Stittelaar, K.J.5
Betjes, M.G.6
-
38
-
-
84879997952
-
Human adipose-tissue derived mesenchymal stem cells induce functional de-novo regulatory T cells with methylated FOXP3 gene DNA
-
Engela, A. U., M. J. Hoogduijn, K. Boer, N. H. Litjens, M. G. Betjes, W. Weimar, and C. C. Baan. 2013. Human adipose-tissue derived mesenchymal stem cells induce functional de-novo regulatory T cells with methylated FOXP3 gene DNA. Clin. Exp. Immunol. 173: 343-354.
-
(2013)
Clin. Exp. Immunol
, vol.173
, pp. 343-354
-
-
Engela, A.U.1
Hoogduijn, M.J.2
Boer, K.3
Litjens, N.H.4
Betjes, M.G.5
Weimar, W.6
Baan, C.C.7
-
39
-
-
65549166894
-
Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenileonset lupus
-
Dai, Z., C. J. Turtle, G. C. Booth, S. R. Riddell, T. A. Gooley, A. M. Stevens, T. Spies, and V. Groh. 2009. Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenileonset lupus. J. Exp. Med. 206: 793-805.
-
(2009)
J. Exp. Med
, vol.206
, pp. 793-805
-
-
Dai, Z.1
Turtle, C.J.2
Booth, G.C.3
Riddell, S.R.4
Gooley, T.A.5
Stevens, A.M.6
Spies, T.7
Groh, V.8
-
40
-
-
0028220396
-
Helper effector function of human T cells stimulated by anti-CD3 mAb can be enhanced by co-stimulatory signals and is partially dependent on CD40- CD40 ligand interaction
-
Kwekkeboom, J., D. de Rijk, A. Kasran, S. Barcy, C. de Groot, and M. de Boer. 1994. Helper effector function of human T cells stimulated by anti-CD3 mAb can be enhanced by co-stimulatory signals and is partially dependent on CD40- CD40 ligand interaction. Eur. J. Immunol. 24: 508-517.
-
(1994)
Eur. J. Immunol
, vol.24
, pp. 508-517
-
-
Kwekkeboom, J.1
De Rijk, D.2
Kasran, A.3
Barcy, S.4
De Groot, C.5
De Boer, M.6
-
41
-
-
0031725838
-
High-level IL-12 production by human dendritic cells requires two signals
-
Snijders, A., P. Kalinski, C. M. Hilkens, and M. L. Kapsenberg. 1998. High-level IL-12 production by human dendritic cells requires two signals. Int. Immunol. 10: 1593-1598.
-
(1998)
Int. Immunol
, vol.10
, pp. 1593-1598
-
-
Snijders, A.1
Kalinski, P.2
Hilkens, C.M.3
Kapsenberg, M.L.4
-
42
-
-
0842265533
-
Blocking B7 and CD40 co-stimulatory molecules decreases antiviral T cell activity
-
Vermeiren, J., J. L. Ceuppens, H. Haegel-Kronenberger, M. De Boer, L. Boon, and S. W. Van Gool. 2004. Blocking B7 and CD40 co-stimulatory molecules decreases antiviral T cell activity. Clin. Exp. Immunol. 135: 253-258.
-
(2004)
Clin. Exp. Immunol
, vol.135
, pp. 253-258
-
-
Vermeiren, J.1
Ceuppens, J.L.2
Haegel-Kronenberger, H.3
De Boer, M.4
Boon, L.5
Van Gool, S.W.6
-
43
-
-
58349116249
-
Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue
-
Wieczorek, G., A. Asemissen, F. Model, I. Turbachova, S. Floess, V. Liebenberg, U. Baron, D. Stauch, K. Kotsch, J. Pratschke, et al. 2009. Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue. Cancer Res. 69: 599-608.
-
(2009)
Cancer Res
, vol.69
, pp. 599-608
-
-
Wieczorek, G.1
Asemissen, A.2
Model, F.3
Turbachova, I.4
Floess, S.5
Liebenberg, V.6
Baron, U.7
Stauch, D.8
Kotsch, K.9
Pratschke, J.10
-
44
-
-
33845990567
-
Functional impairment of monocyte-derived dendritic cells in patients with severe chronic kidney disease
-
Verkade, M. A., C. J. van Druningen, L. M. Vaessen, D. A. Hesselink, W. Weimar, and M. G. Betjes. 2007. Functional impairment of monocyte-derived dendritic cells in patients with severe chronic kidney disease. Nephrol. Dial. Transplant. 22: 128-138.
-
(2007)
Nephrol. Dial. Transplant
, vol.22
, pp. 128-138
-
-
Verkade, M.A.1
Van Druningen, C.J.2
Vaessen, L.M.3
Hesselink, D.A.4
Weimar, W.5
Betjes, M.G.6
-
45
-
-
3242801352
-
Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells
-
Hoffmann, P., R. Eder, L. A. Kunz-Schughart, R. Andreesen, and M. Edinger. 2004. Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells. Blood 104: 895-903.
-
(2004)
Blood
, vol.104
, pp. 895-903
-
-
Hoffmann, P.1
Eder, R.2
Kunz-Schughart, L.A.3
Andreesen, R.4
Edinger, M.5
-
46
-
-
0035554678
-
Inducible IL-2 production by dendritic cells revealed by global gene expression analysis
-
Granucci, F., C. Vizzardelli, N. Pavelka, S. Feau, M. Persico, E. Virzi, M. Rescigno, G. Moro, and P. Ricciardi-Castagnoli. 2001. Inducible IL-2 production by dendritic cells revealed by global gene expression analysis. Nat. Immunol. 2: 882-888.
-
(2001)
Nat. Immunol
, vol.2
, pp. 882-888
-
-
Granucci, F.1
Vizzardelli, C.2
Pavelka, N.3
Feau, S.4
Persico, M.5
Virzi, E.6
Rescigno, M.7
Moro, G.8
Ricciardi-Castagnoli, P.9
-
47
-
-
65449141433
-
Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation
-
Hoffmann, P., T. J. Boeld, R. Eder, J. Huehn, S. Floess, G. Wieczorek, S. Olek, W. Dietmaier, R. Andreesen, and M. Edinger. 2009. Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation. Eur. J. Immunol. 39: 1088-1097.
-
(2009)
Eur. J. Immunol
, vol.39
, pp. 1088-1097
-
-
Hoffmann, P.1
Boeld, T.J.2
Eder, R.3
Huehn, J.4
Floess, S.5
Wieczorek, G.6
Olek, S.7
Dietmaier, W.8
Andreesen, R.9
Edinger, M.10
-
48
-
-
65549115862
-
Plasticity of CD4+ T cell lineage differentiation
-
Zhou, L., M. M. Chong, and D. R. Littman. 2009. Plasticity of CD4+ T cell lineage differentiation. Immunity 30: 646-655.
-
(2009)
Immunity
, vol.30
, pp. 646-655
-
-
Zhou, L.1
Chong, M.M.2
Littman, D.R.3
-
49
-
-
67049168780
-
Plasticity of CD4(+) FoxP3(+) T cells
-
Zhou, X., S. Bailey-Bucktrout, L. T. Jeker, and J. A. Bluestone. 2009. Plasticity of CD4(+) FoxP3(+) T cells. Curr. Opin. Immunol. 21: 281-285.
-
(2009)
Curr. Opin. Immunol
, vol.21
, pp. 281-285
-
-
Zhou, X.1
Bailey-Bucktrout, S.2
Jeker, L.T.3
Bluestone, J.A.4
-
50
-
-
0036379775
-
X-chromosome inactivation analysis in a female carrier of FOXP3 mutation
-
Tommasini, A., S. Ferrari, D. Moratto, R. Badolato, M. Boniotto, D. Pirulli, L. D. Notarangelo, and M. Andolina. 2002. X-chromosome inactivation analysis in a female carrier of FOXP3 mutation. Clin. Exp. Immunol. 130: 127-130.
-
(2002)
Clin. Exp. Immunol
, vol.130
, pp. 127-130
-
-
Tommasini, A.1
Ferrari, S.2
Moratto, D.3
Badolato, R.4
Boniotto, M.5
Pirulli, D.6
Notarangelo, L.D.7
Andolina, M.8
-
51
-
-
84874232301
-
Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans
-
Himmel, M. E., K. G. MacDonald, R. V. Garcia, T. S. Steiner, and M. K. Levings. 2013. Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans. J. Immunol. 190: 2001-2008.
-
(2013)
J. Immunol
, vol.190
, pp. 2001-2008
-
-
Himmel, M.E.1
Macdonald, K.G.2
Garcia, R.V.3
Steiner, T.S.4
Levings, M.K.5
-
52
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
Takahashi, T., T. Tagami, S. Yamazaki, T. Uede, J. Shimizu, N. Sakaguchi, T. W. Mak, and S. Sakaguchi. 2000. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med. 192: 303-310.
-
(2000)
J. Exp. Med
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
Uede, T.4
Shimizu, J.5
Sakaguchi, N.6
Mak, T.W.7
Sakaguchi, S.8
-
53
-
-
0036467522
-
CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
-
Kingsley, C. I., M. Karim, A. R. Bushell, and K. J. Wood. 2002. CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J. Immunol. 168: 1080-1086.
-
(2002)
J. Immunol
, vol.168
, pp. 1080-1086
-
-
Kingsley, C.I.1
Karim, M.2
Bushell, A.R.3
Wood, K.J.4
-
54
-
-
33747303831
-
Signatures of human regulatory T cells: An encounter with old friends and new players
-
Pfoertner, S., A. Jeron, M. Probst-Kepper, C. A. Guzman, W. Hansen, A. M. Westendorf, T. Toepfer, A. J. Schrader, A. Franzke, J. Buer, and R. Geffers. 2006. Signatures of human regulatory T cells: an encounter with old friends and new players. Genome Biol. 7: R54.
-
(2006)
Genome Biol
, vol.7
, pp. R54
-
-
Pfoertner, S.1
Jeron, A.2
Probst-Kepper, M.3
Guzman, C.A.4
Hansen, W.5
Westendorf, A.M.6
Toepfer, T.7
Schrader, A.J.8
Franzke, A.9
Buer, J.10
Geffers, R.11
-
55
-
-
80054079921
-
Next-generation insights into regulatory T cells: Expression profiling and FoxP3 occupancy in Human
-
Birzele, F., T. Fauti, H. Stahl, M. C. Lenter, E. Simon, D. Knebel, A. Weith, T. Hildebrandt, and D. Mennerich. 2011. Next-generation insights into regulatory T cells: expression profiling and FoxP3 occupancy in Human. Nucleic Acids Res. 39: 7946-7960.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 7946-7960
-
-
Birzele, F.1
Fauti, T.2
Stahl, H.3
Lenter, M.C.4
Simon, E.5
Knebel, D.6
Weith, A.7
Hildebrandt, T.8
Mennerich, D.9
-
56
-
-
77955486658
-
Genome-wide identification of human FOXP3 target genes in natural regulatory T cells
-
Sadlon, T. J., B. G. Wilkinson, S. Pederson, C. Y. Brown, S. Bresatz, T. Gargett, E. L. Melville, K. Peng, R. J. D'Andrea, G. G. Glonek, et al. 2010. Genome-wide identification of human FOXP3 target genes in natural regulatory T cells. J. Immunol. 185: 1071-1081.
-
(2010)
J. Immunol
, vol.185
, pp. 1071-1081
-
-
Sadlon, T.J.1
Wilkinson, B.G.2
Pederson, S.3
Brown, C.Y.4
Bresatz, S.5
Gargett, T.6
Melville, E.L.7
Peng, K.8
D'Andrea, R.J.9
Glonek, G.G.10
-
57
-
-
84880418854
-
Developmental plasticity of murine and human Foxp3(+) regulatory T cells
-
Liston, A., and C. A. Piccirillo. 2013. Developmental plasticity of murine and human Foxp3(+) regulatory T cells. Adv. Immunol. 119: 85-106.
-
(2013)
Adv. Immunol
, vol.119
, pp. 85-106
-
-
Liston, A.1
Piccirillo, C.A.2
-
58
-
-
51549104932
-
IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development
-
Vang, K. B., J. Yang, S. A. Mahmud, M. A. Burchill, A. L. Vegoe, and M. A. Farrar. 2008. IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development. J. Immunol. 181: 3285-3290.
-
(2008)
J. Immunol
, vol.181
, pp. 3285-3290
-
-
Vang, K.B.1
Yang, J.2
Mahmud, S.A.3
Burchill, M.A.4
Vegoe, A.L.5
Farrar, M.A.6
-
59
-
-
54249117326
-
The influence of IL-2 family cytokines on activation and function of naturally occurring regulatory T cells
-
Wuest, T. Y., J. Willette-Brown, S. K. Durum, and A. A. Hurwitz. 2008. The influence of IL-2 family cytokines on activation and function of naturally occurring regulatory T cells. J. Leukoc. Biol. 84: 973-980.
-
(2008)
J. Leukoc. Biol
, vol.84
, pp. 973-980
-
-
Wuest, T.Y.1
Willette-Brown, J.2
Durum, S.K.3
Hurwitz, A.A.4
-
60
-
-
34447574943
-
The maintenance of human CD4+ CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro
-
Yates, J., F. Rovis, P. Mitchell, B. Afzali, J. Tsang, M. Garin, R. I. Lechler, G. Lombardi, and O. A. Garden. 2007. The maintenance of human CD4+ CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro. Int. Immunol. 19: 785-799.
-
(2007)
Int. Immunol
, vol.19
, pp. 785-799
-
-
Yates, J.1
Rovis, F.2
Mitchell, P.3
Afzali, B.4
Tsang, J.5
Garin, M.6
Lechler, R.I.7
Lombardi, G.8
Garden, O.A.9
-
61
-
-
27544446622
-
Development and function of agonistinduced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling
-
D'Cruz, L. M., and L. Klein. 2005. Development and function of agonistinduced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling. Nat. Immunol. 6: 1152-1159.
-
(2005)
Nat. Immunol
, vol.6
, pp. 1152-1159
-
-
D'Cruz, L.M.1
Klein, L.2
-
62
-
-
27544481941
-
A function for interleukin 2 in Foxp3-expressing regulatory T cells
-
Fontenot, J. D., J. P. Rasmussen, M. A. Gavin, and A. Y. Rudensky. 2005. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6: 1142-1151.
-
(2005)
Nat. Immunol
, vol.6
, pp. 1142-1151
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Gavin, M.A.3
Rudensky, A.Y.4
-
63
-
-
33845935950
-
IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells
-
Burchill, M. A., J. Yang, C. Vogtenhuber, B. R. Blazar, and M. A. Farrar. 2007. IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells. J. Immunol. 178: 280-290.
-
(2007)
J. Immunol
, vol.178
, pp. 280-290
-
-
Burchill, M.A.1
Yang, J.2
Vogtenhuber, C.3
Blazar, B.R.4
Farrar, M.A.5
-
64
-
-
0038752591
-
Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming
-
Granucci, F., S. Feau, V. Angeli, F. Trottein, and P. Ricciardi-Castagnoli. 2003. Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming. J. Immunol. 170: 5075-5081.
-
(2003)
J. Immunol
, vol.170
, pp. 5075-5081
-
-
Granucci, F.1
Feau, S.2
Angeli, V.3
Trottein, F.4
Ricciardi-Castagnoli, P.5
-
65
-
-
11244277486
-
Dendritic cellderived IL-2 production is regulated by IL-15 in humans and in mice
-
Feau, S., V. Facchinetti, F. Granucci, S. Citterio, D. Jarrossay, S. Seresini, M. P. Protti, A. Lanzavecchia, and P. Ricciardi-Castagnoli. 2005. Dendritic cellderived IL-2 production is regulated by IL-15 in humans and in mice. Blood 105: 697-702.
-
(2005)
Blood
, vol.105
, pp. 697-702
-
-
Feau, S.1
Facchinetti, V.2
Granucci, F.3
Citterio, S.4
Jarrossay, D.5
Seresini, S.6
Protti, M.P.7
Lanzavecchia, A.8
Ricciardi-Castagnoli, P.9
-
66
-
-
29644434293
-
Specificity of CD4+CD25+ regulatory T cell function in alloimmunity
-
Sánchez-Fueyo, A., S. Sandner, A. Habicht, C. Mariat, J. Kenny, N. Degauque, X. X. Zheng, T. B. Strom, L. A. Turka, and M. H. Sayegh. 2006. Specificity of CD4+CD25+ regulatory T cell function in alloimmunity. J. Immunol. 176: 329-334.
-
(2006)
J. Immunol
, vol.176
, pp. 329-334
-
-
Sánchez-Fueyo, A.1
Sandner, S.2
Habicht, A.3
Mariat, C.4
Kenny, J.5
Degauque, N.6
Zheng, X.X.7
Strom, T.B.8
Turka, L.A.9
Sayegh, M.H.10
-
67
-
-
84862791213
-
Regulatory T cell migration during an immune response
-
Ding, Y., J. Xu, and J. S. Bromberg. 2012. Regulatory T cell migration during an immune response. Trends Immunol. 33: 174-180.
-
(2012)
Trends Immunol
, vol.33
, pp. 174-180
-
-
Ding, Y.1
Xu, J.2
Bromberg, J.S.3
-
68
-
-
84055170530
-
Role of dendritic cell maturity/costimulation for generation, homeostasis, and suppressive activity of regulatory T cells
-
Pletinckx, K., A. Döhler, V. Pavlovic, and M. B. Lutz. 2011. Role of dendritic cell maturity/costimulation for generation, homeostasis, and suppressive activity of regulatory T cells. Front. Immunol. 2: 39.
-
(2011)
Front. Immunol
, vol.2
, pp. 39
-
-
Pletinckx, K.1
Döhler, A.2
Pavlovic, V.3
Lutz, M.B.4
-
69
-
-
55849107041
-
The kinetics of CD4+Foxp3+ T cell accumulation during a human cutaneous antigen-specific memory response in vivo
-
Vukmanovic-Stejic, M., E. Agius, N. Booth, P. J. Dunne, K. E. Lacy, J. R. Reed, T. O. Sobande, S. Kissane, M. Salmon, M. H. Rustin, and A. N. Akbar. 2008. The kinetics of CD4+Foxp3+ T cell accumulation during a human cutaneous antigen-specific memory response in vivo. J. Clin. Invest. 118: 3639-3650.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 3639-3650
-
-
Vukmanovic-Stejic, M.1
Agius, E.2
Booth, N.3
Dunne, P.J.4
Lacy, K.E.5
Reed, J.R.6
Sobande, T.O.7
Kissane, S.8
Salmon, M.9
Rustin, M.H.10
Akbar, A.N.11
-
70
-
-
84896697076
-
Novel GMPcompatible protocol employing an allogeneic B cell bank for clonal expansion of allospecific natural regulatory T cells
-
Landwehr-Kenzel, S., F. Issa, S. H. Luu, M. Schmück, H. Lei, A. Zobel, A. Thiel, N. Babel, K. Wood, H. D. Volk, and P. Reinke. 2014. Novel GMPcompatible protocol employing an allogeneic B cell bank for clonal expansion of allospecific natural regulatory T cells. Am. J. Transplant. 14: 594-606.
-
(2014)
Am. J. Transplant
, vol.14
, pp. 594-606
-
-
Landwehr-Kenzel, S.1
Issa, F.2
Luu, S.H.3
Schmück, M.4
Lei, H.5
Zobel, A.6
Thiel, A.7
Babel, N.8
Wood, K.9
Volk, H.D.10
Reinke, P.11
|