메뉴 건너뛰기




Volumn 114, Issue 18, 2009, Pages 3947-3955

The human alloreactive CD4+ T-cell repertoire is biased to a Th17 response and the frequency is inversely related to the number of HLA class II mismatches

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 2; MINOR HISTOCOMPATIBILITY ANTIGEN; ANTINEOPLASTIC AGENT; CD40 LIGAND; IL2 PROTEIN, HUMAN; INTERLEUKIN 2;

EID: 70449730679     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-03-211896     Document Type: Article
Times cited : (31)

References (34)
  • 1
    • 0024993328 scopus 로고
    • Cytoxic T cell recognition of an endogenous class I HLA peptide presented by a HLA molecule
    • Chen BP, Madrigal A, Parham P. Cytoxic T cell recognition of an endogenous class I HLA peptide presented by a HLA molecule. J Exp Med. 1990;172(3):779-788.
    • (1990) J Exp Med , vol.172 , Issue.3 , pp. 779-788
    • Chen, B.P.1    Madrigal, A.2    Parham, P.3
  • 2
    • 0030272420 scopus 로고    scopus 로고
    • Antigen processing and presentation in transplantation
    • Auchincloss H Jr, Sultan H. Antigen processing and presentation in transplantation. Curr Opin Immunol. 1996;8(5):681-687.
    • (1996) Curr Opin Immunol , vol.8 , Issue.5 , pp. 681-687
    • Auchincloss Jr., H.1    Sultan, H.2
  • 3
    • 4344617233 scopus 로고    scopus 로고
    • Mechanism of action of donor-specific transfusion in inducing tolerance: Role of donor MHC molecules, donor co-stimulatory molecules, and indirect antigen presentation
    • Kishimoto K, Yuan X, Auchincloss H Jr, Sharpe HH, Mandelbrot DA, Sayegh MH. Mechanism of action of donor-specific transfusion in inducing tolerance: role of donor MHC molecules, donor co-stimulatory molecules, and indirect antigen presentation. J Am Soc Nephrol. 2004;15(9):2423-2428.
    • (2004) J Am Soc Nephrol , vol.15 , Issue.9 , pp. 2423-2428
    • Kishimoto, K.1    Yuan, X.2    Auchincloss Jr., H.3    Sharpe, H.H.4    Mandelbrot, D.A.5    Sayegh, M.H.6
  • 4
    • 0033083953 scopus 로고    scopus 로고
    • Direct and indirect recognition: The role of MHC antigens in graft rejection
    • Gould DS, Auchincloss H Jr. Direct and indirect recognition: the role of MHC antigens in graft rejection. Immunol Today. 1999;20(2):77-82.
    • (1999) Immunol Today , vol.20 , Issue.2 , pp. 77-82
    • Gould, D.S.1    Auchincloss Jr., H.2
  • 5
    • 21344457939 scopus 로고    scopus 로고
    • Indirect recognition of MHC class I allopeptides accelerates lung allograft rejection in miniature swine
    • Shoji T, Wain JC, Houser SL, et al. Indirect recognition of MHC class I allopeptides accelerates lung allograft rejection in miniature swine. Am J Transplant. 2005;5(7):1626-1634.
    • (2005) Am J Transplant , vol.5 , Issue.7 , pp. 1626-1634
    • Shoji, T.1    Wain, J.C.2    Houser, S.L.3
  • 6
    • 1942451803 scopus 로고    scopus 로고
    • Depleting anti-CD4 monoclonal antibody cures new-onset diabetes, prevents recurrent autoimmune diabetes, and delays allograft rejection in nonobese diabetic mice
    • Makhlouf L, Grey ST, Dong V, et al. Depleting anti-CD4 monoclonal antibody cures new-onset diabetes, prevents recurrent autoimmune diabetes, and delays allograft rejection in nonobese diabetic mice. Transplantation. 2004;77(7):990-997.
    • (2004) Transplantation , vol.77 , Issue.7 , pp. 990-997
    • Makhlouf, L.1    Grey, S.T.2    Dong, V.3
  • 7
    • 41149094672 scopus 로고    scopus 로고
    • Defective alloreactive CD8 T cell function and memory response in allograft recipients in the absence of CD4 help
    • Zhai Y, Wang Y, Wu Z, Kupiec-Weglinski JW. Defective alloreactive CD8 T cell function and memory response in allograft recipients in the absence of CD4 help. J Immunol. 2007;179(7):4529-4534.
    • (2007) J Immunol , vol.179 , Issue.7 , pp. 4529-4534
    • Zhai, Y.1    Wang, Y.2    Wu, Z.3    Kupiec-Weglinski, J.W.4
  • 8
    • 34548356891 scopus 로고    scopus 로고
    • Allopeptide-specific CD4(+) T cells facilitate the differentiation of directly alloreactive graft-infiltrating CD8(+) T Cells
    • Richards DM, Zhang N, Dalheimer SL, Mueller DL. Allopeptide-specific CD4(+) T cells facilitate the differentiation of directly alloreactive graft-infiltrating CD8(+) T Cells. Am J Transplant. 2007;7(10):2269-2278.
    • (2007) Am J Transplant , vol.7 , Issue.10 , pp. 2269-2278
    • Richards, D.M.1    Zhang, N.2    Dalheimer, S.L.3    Mueller, D.L.4
  • 9
    • 0036775284 scopus 로고    scopus 로고
    • Regulatory functions of human CD4(+) T cells recognizing allopeptides in the context of self-HLA class II
    • Roelen DL, van Bree S, van Hulst P, van Beelen E, Claas FH. Regulatory functions of human CD4(+) T cells recognizing allopeptides in the context of self-HLA class II. Hum Immunol. 2002;63(10):902-911.
    • (2002) Hum Immunol , vol.63 , Issue.10 , pp. 902-911
    • Roelen, D.L.1    Van Bree, S.2    Van Hulst, P.3    Van Beelen, E.4    Claas, F.H.5
  • 10
    • 25444508245 scopus 로고    scopus 로고
    • Sayegh MH.T-cell costimulatory pathways in allograft rejection and tolerance
    • Clarkson MR, Sayegh MH.T-cell costimulatory pathways in allograft rejection and tolerance. Transplantation. 2005;80(5):555-563.
    • (2005) Transplantation , vol.80 , Issue.5 , pp. 555-563
    • Clarkson, M.R.1
  • 11
    • 0031977605 scopus 로고    scopus 로고
    • The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells
    • Mackey MF, Barth RJ Jr, Noelle RJ. The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells. J Leukoc Biol. 1998;63(4):418-428.
    • (1998) J Leukoc Biol , vol.63 , Issue.4 , pp. 418-428
    • Mackey, M.F.1    Barth Jr., R.J.2    Noelle, R.J.3
  • 12
    • 0037443493 scopus 로고    scopus 로고
    • Activation of alloreactive CD8+ T cells operates via CD4-dependent and CD4-independent mechanisms and is CD154 blockade sensitive
    • ZhaiY, Meng L, Busuttil RW, Sayegh MH, Kupiec-Weglinski JW. Activation of alloreactive CD8+ T cells operates via CD4-dependent and CD4-independent mechanisms and is CD154 blockade sensitive. J Immunol. 2003;170(6):3024-3028.
    • (2003) J Immunol , vol.170 , Issue.6 , pp. 3024-3028
    • Zhaiy Meng, L.1    Busuttil, R.W.2    Sayegh, M.H.3    Kupiec-Weglinski, J.W.4
  • 14
    • 27144540183 scopus 로고    scopus 로고
    • + T cells specific for defined antigens according to CD154 expression
    • + T cells specific for defined antigens according to CD154 expression. Nat Med. 2005;11(10):1118-1124.
    • (2005) Nat Med , vol.11 , Issue.10 , pp. 1118-1124
    • Frentsch, M.1    Arbach, O.2    Kirchhoff, D.3
  • 15
    • 50849124444 scopus 로고    scopus 로고
    • Expansion of cytolytic CD4+CD28- T cells in end-stage renal disease
    • Betjes MG, Huisman M, Weimar W, Litjens NH. Expansion of cytolytic CD4+CD28- T cells in end-stage renal disease. Kidney Int. 2008;74(6):760-767.
    • (2008) Kidney Int , vol.74 , Issue.6 , pp. 760-767
    • Betjes, M.G.1    Huisman, M.2    Weimar, W.3    Litjens, N.H.4
  • 16
    • 29444433970 scopus 로고    scopus 로고
    • Progressive loss of renal function is associated with activation and depletion of naive T lymphocytes
    • Litjens NH, van Druningen CJ, Betjes MG. Progressive loss of renal function is associated with activation and depletion of naive T lymphocytes. Clin Immunol. 2006;118(1):83-91.
    • (2006) Clin Immunol , vol.118 , Issue.1 , pp. 83-91
    • Litjens, N.H.1    Van Druningen, C.J.2    Betjes, M.G.3
  • 17
    • 38349171278 scopus 로고    scopus 로고
    • Hepatitis B vaccine-specific CD4(+) T cells can be detected and characterised at the single cell level: Limited usefulness of dendritic cells as signal enhancers
    • Litjens NH, Huisman M, Baan CC, van Druningen CJ, Betjes MG. Hepatitis B vaccine-specific CD4(+) T cells can be detected and characterised at the single cell level: limited usefulness of dendritic cells as signal enhancers. J Immunol Methods. 2008;330(1-2):1-11.
    • (2008) J Immunol Methods , vol.330 , Issue.1-2 , pp. 1-11
    • Litjens, N.H.1    Huisman, M.2    Baan, C.C.3    Van Druningen, C.J.4    Betjes, M.G.5
  • 18
    • 0033566737 scopus 로고    scopus 로고
    • Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes
    • Heeger PS, Greenspan NS, Kuhlenschmidt S, et al. Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes. J Immunol. 1999;163(4):2267-2275.
    • (1999) J Immunol , vol.163 , Issue.4 , pp. 2267-2275
    • Heeger, P.S.1    Greenspan, N.S.2    Kuhlenschmidt, S.3
  • 20
    • 0028939698 scopus 로고
    • A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex
    • Casamayor-Palleja M, Khan M, MacLennan IC. A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex. J Exp Med. 1995;181(4):1293-1301.
    • (1995) J Exp Med , vol.181 , Issue.4 , pp. 1293-1301
    • Casamayor-Palleja, M.1    Khan, M.2    MacLennan, I.C.3
  • 21
    • 34948892926 scopus 로고    scopus 로고
    • Preformed CD40 ligand exists in secretory lysosomes in effector and memory CD4+ T cells and is quickly expressed on the cell surface in an antigen-specific manner
    • Koguchi Y, Thauland TJ, Slifka MK, Parker DC. Preformed CD40 ligand exists in secretory lysosomes in effector and memory CD4+ T cells and is quickly expressed on the cell surface in an antigen-specific manner. Blood. 2007;110(7):2520-2527.
    • (2007) Blood , vol.110 , Issue.7 , pp. 2520-2527
    • Koguchi, Y.1    Thauland, T.J.2    Slifka, M.K.3    Parker, D.C.4
  • 22
    • 0036721711 scopus 로고    scopus 로고
    • IL-2 receptor blockade inhibits late, but not early, IFN-gamma and CD40 ligand expression in human T cells: Disruption of both IL-12-dependent and -independent pathways of IFN-gamma production
    • McDyer JF, Li Z, John S, Yu X, Wu CY, Ragheb JA. IL-2 receptor blockade inhibits late, but not early, IFN-gamma and CD40 ligand expression in human T cells: disruption of both IL-12-dependent and -independent pathways of IFN-gamma production. J Immunol. 2002;169(5):2736-2746.
    • (2002) J Immunol , vol.169 , Issue.5 , pp. 2736-2746
    • McDyer, J.F.1    Li, Z.2    John, S.3    Yu, X.4    Wu, C.Y.5    Ragheb, J.A.6
  • 23
    • 34250024900 scopus 로고    scopus 로고
    • Direct inhibition of CD40L expression can contribute to the clinical efficacy of daclizumab independently of its effects on cell division and Th1/Th2 cytokine production
    • Snyder JT, Shen J, Azmi H, Hou J, Fowler DH, Ragheb JA. Direct inhibition of CD40L expression can contribute to the clinical efficacy of daclizumab independently of its effects on cell division and Th1/Th2 cytokine production. Blood. 2007;109(12):5399-5406.
    • (2007) Blood , vol.109 , Issue.12 , pp. 5399-5406
    • Snyder, J.T.1    Shen, J.2    Azmi, H.3    Hou, J.4    Fowler, D.H.5    Ragheb, J.A.6
  • 24
    • 4644293264 scopus 로고    scopus 로고
    • Ten Berge IJ. Differentiation of human alloreactive CD4+ and CD8+ T cells in vitro
    • Nikolaeva N, Uss E, van Leeuwen EM, van Lier RA, ten Berge IJ. Differentiation of human alloreactive CD4+ and CD8+ T cells in vitro. Transplantation. 2004;78(6):815-824.
    • (2004) Transplantation , vol.78 , Issue.6 , pp. 815-824
    • Nikolaeva, N.1    Uss, E.2    Van Leeuwen, E.M.3    Van Lier, R.A.4
  • 25
    • 36448937145 scopus 로고    scopus 로고
    • Specificity of T-cell alloreactivity
    • Felix NJ, Allen PM. Specificity of T-cell alloreactivity. Nat Rev Immunol. 2007;7(12):942-953.
    • (2007) Nat Rev Immunol , vol.7 , Issue.12 , pp. 942-953
    • Felix, N.J.1    Allen, P.M.2
  • 26
    • 0033571515 scopus 로고    scopus 로고
    • The new-generation therapeutic anti-CD25 monoclonal antibodies
    • Williams KA, Thiel MA, Zola H. The new-generation therapeutic anti-CD25 monoclonal antibodies. Transplantation. 1999;68(9):1228-1229.
    • (1999) Transplantation , vol.68 , Issue.9 , pp. 1228-1229
    • Williams, K.A.1    Thiel, Ma.2    Zola, H.3
  • 28
    • 0031903820 scopus 로고    scopus 로고
    • Interleukin-17 activates human renal epithelial cells in vitro and is expressed during renal allograft rejection
    • Van Kooten C, Boonstra JG, Paape ME, et al. Interleukin-17 activates human renal epithelial cells in vitro and is expressed during renal allograft rejection. J Am Soc Nephrol. 1998;9(8):1526-1534.
    • (1998) J Am Soc Nephrol , vol.9 , Issue.8 , pp. 1526-1534
    • Van Kooten, C.1    Boonstra, J.G.2    Paape, M.E.3
  • 29
    • 0036063633 scopus 로고    scopus 로고
    • Evidence for the early involvement of interleukin 17 in human and experimental renal allograft rejection
    • Loong CC, Hsieh HG, Lui WY, Chen A, Lin CY. Evidence for the early involvement of interleukin 17 in human and experimental renal allograft rejection. J Pathol. 2002;197(3):322-332.
    • (2002) J Pathol , vol.197 , Issue.3 , pp. 322-332
    • Loong, C.C.1    Hsieh, H.G.2    Lui, W.Y.3    Chen, A.4    Lin, C.Y.5
  • 30
    • 0033765333 scopus 로고    scopus 로고
    • Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells
    • Woltman AM, de Haij S, Boonstra JG, Gobin SJ, Daha MR, van Kooten C. Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells. J Am Soc Nephrol. 2000;11(11):2044-2055.
    • (2000) J Am Soc Nephrol , vol.11 , Issue.11 , pp. 2044-2055
    • Woltman, A.M.1    De Haij, S.2    Boonstra, J.G.3    Gobin, S.J.4    Daha, M.R.5    Van Kooten, C.6
  • 32
    • 59649098784 scopus 로고    scopus 로고
    • IL-17 contributes to CD4-mediated graft-versus-host disease
    • Kappel LW, Goldberg GL, King CG, et al. IL-17 contributes to CD4-mediated graft-versus-host disease. Blood. 2009;113(4):945-952.
    • (2009) Blood , vol.113 , Issue.4 , pp. 945-952
    • Kappel, L.W.1    Goldberg, G.L.2    King, C.G.3
  • 33
    • 0037467793 scopus 로고    scopus 로고
    • Early versus late acute rejection episodes in renal transplantation
    • SijpkensYW, Doxiadis II, Mallat MJ, et al. Early versus late acute rejection episodes in renal transplantation. Transplantation. 2003;75(2):204-208.
    • (2003) Transplantation , vol.75 , Issue.2 , pp. 204-208
    • Sijpkensyw II, D.1    Mallat, M.J.2
  • 34
    • 36048968753 scopus 로고    scopus 로고
    • IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants
    • Burlingham WJ, Love RB, Jankowska-Gan E, et al. IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants. J Clin Invest. 2007;117:3498-3506.
    • (2007) J Clin Invest , vol.117 , pp. 3498-3506
    • Burlingham, W.J.1    Love, R.B.2    Jankowska-Gan, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.