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Volumn 20, Issue 3, 2015, Pages 3791-3810

Lectins with potential for anti-cancer therapy

Author keywords

Apoptosis; Autophagy; Cancer cells; Lectins

Indexed keywords

ANTINEOPLASTIC AGENT; LECTIN;

EID: 84929587322     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules20033791     Document Type: Review
Times cited : (190)

References (96)
  • 1
    • 84936992297 scopus 로고    scopus 로고
    • Section 11.4, Lectins Are Specific Carbohydrate-Binding Proteins
    • W H Freeman: New York, NY, USA
    • Berg, J.M.; Tymoczko, J.L.; Stryer, L. Section 11.4, Lectins Are Specific Carbohydrate-Binding Proteins. In Biochemistry, 5th ed.; W H Freeman: New York, NY, USA, 2002.
    • (2002) Biochemistry, 5th Ed.
    • Berg, J.M.1    Tymoczko, J.L.2    Stryer, L.3
  • 2
    • 77949653079 scopus 로고    scopus 로고
    • Section 4.1, The purification of proteins is an essential first step in understanding their function
    • W H Freeman: New York, NY, USA
    • Berg, J.M.; Tymoczko, J.L.; Stryer, L. Section 4.1, The purification of proteins is an essential first step in understanding their function. In Biochemistry, 5th ed.; W H Freeman: New York, NY, USA, 2002.
    • (2002) Biochemistry, 5th Ed.
    • Berg, J.M.1    Tymoczko, J.L.2    Stryer, L.3
  • 3
    • 0020774097 scopus 로고
    • An insertion sequence blocks the expression of a soybean lectin gene
    • Goldberg, R.B.; Hoschek, G.; Vodkin, L.O. An insertion sequence blocks the expression of a soybean lectin gene. Cell 1983, 33, 465-475.
    • (1983) Cell , vol.33 , pp. 465-475
    • Goldberg, R.B.1    Hoschek, G.2    Vodkin, L.O.3
  • 5
    • 84879155766 scopus 로고    scopus 로고
    • Measuring apoptosis by microscopy and flow cytometry
    • Henry, C.M.; Hollville, E.; Martin, S.J. Measuring apoptosis by microscopy and flow cytometry. Methods 2003, 61, 90-97.
    • (2003) Methods , vol.61 , pp. 90-97
    • Henry, C.M.1    Hollville, E.2    Martin, S.J.3
  • 6
    • 84865547975 scopus 로고    scopus 로고
    • Identification of microRNA-regulated autophagic pathways in plant lectin-induced cancer cell death
    • Fu, L.L.; Zhao, X.; Xu, H.L.; Wen, X.; Wang, S.Y.; Liu, B.; Bao, J.K.; Wei, Y.Q. Identification of microRNA-regulated autophagic pathways in plant lectin-induced cancer cell death. Cell Prolif. 2012, 45, 477-485.
    • (2012) Cell Prolif. , vol.45 , pp. 477-485
    • Fu, L.L.1    Zhao, X.2    Xu, H.L.3    Wen, X.4    Wang, S.Y.5    Liu, B.6    Bao, J.K.7    Wei, Y.Q.8
  • 7
    • 78650321191 scopus 로고    scopus 로고
    • Down-regulation of some miRNAs by degrading their precursors contributes to anti-cancer effect of mistletoe lectin-I
    • Li, L.N.; Zhang, H.D.; Zhi, R.; Yuan, S.J. Down-regulation of some miRNAs by degrading their precursors contributes to anti-cancer effect of mistletoe lectin-I. Br. J. Pharmacol. 2011, 162, 349-364.
    • (2011) Br. J. Pharmacol. , vol.162 , pp. 349-364
    • Li, L.N.1    Zhang, H.D.2    Zhi, R.3    Yuan, S.J.4
  • 8
    • 18044396712 scopus 로고    scopus 로고
    • On the role of galectin-3 in cancer apoptosis
    • Nakahara, S.; Oka, N.; Raz, A. On the role of galectin-3 in cancer apoptosis. Apoptosis 2005, 10, 267-275.
    • (2005) Apoptosis , vol.10 , pp. 267-275
    • Nakahara, S.1    Oka, N.2    Raz, A.3
  • 9
    • 39549123615 scopus 로고    scopus 로고
    • Biological modulation by lectins and their ligands in tumor progression and metastasis
    • Nakahara, S.; Raz, A. Biological modulation by lectins and their ligands in tumor progression and metastasis. AntiCancer Agents Med. Chem. 2008, 8, 22-36.
    • (2008) AntiCancer Agents Med. Chem. , vol.8 , pp. 22-36
    • Nakahara, S.1    Raz, A.2
  • 12
    • 0033613211 scopus 로고    scopus 로고
    • Galectin-7 overexpression is associated with the apoptotic process in UVB-induced sunburn keratinocytes
    • Bernerd, F.; Sarasin, A.; Magnaldo, T. Galectin-7 overexpression is associated with the apoptotic process in UVB-induced sunburn keratinocytes. Proc. Natl. Acad. Sci. USA 1999, 96, 11329-11334.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11329-11334
    • Bernerd, F.1    Sarasin, A.2    Magnaldo, T.3
  • 13
    • 49149130853 scopus 로고    scopus 로고
    • Glycosylation-dependent interactions of C-type lectin DC-SIGN with colorectal tumor-associated Lewis glycans impair the function and differentiation of monocyte-derived dendritic cells
    • Nonaka, M.; Ma, B.Y.; Murai, R.; Nakamura, N.; Baba, M.; Kawasaki, N.; Hodohara, K.; Asano, S.; Kawasaki, T. Glycosylation-dependent interactions of C-type lectin DC-SIGN with colorectal tumor-associated Lewis glycans impair the function and differentiation of monocyte-derived dendritic cells. J. Immunol. 2008, 180, 3347-3356.
    • (2008) J. Immunol. , vol.180 , pp. 3347-3356
    • Nonaka, M.1    Ma, B.Y.2    Murai, R.3    Nakamura, N.4    Baba, M.5    Kawasaki, N.6    Hodohara, K.7    Asano, S.8    Kawasaki, T.9
  • 14
    • 57949099850 scopus 로고    scopus 로고
    • Bringing natural killer cells to the clinic: Ex vivo manipulation
    • Srivastava, S.; Lundqvist, A.; Childs, R.W. Bringing natural killer cells to the clinic: Ex vivo manipulation. Cytotherapy 2008, 10, 775-783.
    • (2008) Cytotherapy , vol.10 , pp. 775-783
    • Srivastava, S.1    Lundqvist, A.2    Childs, R.W.3
  • 15
    • 84869107330 scopus 로고    scopus 로고
    • Animal lectins: Potential antitumor therapeutic targets in apoptosis
    • Liu, Z.; Zhang, Q.; Peng, H.; Zhang, W. Animal lectins: potential antitumor therapeutic targets in apoptosis. Appl. Biochem. Biotechnol. 2012, 168, 629-637.
    • (2012) Appl. Biochem. Biotechnol. , vol.168 , pp. 629-637
    • Liu, Z.1    Zhang, Q.2    Peng, H.3    Zhang, W.4
  • 16
    • 77950235551 scopus 로고    scopus 로고
    • Annexin 1 induced by anti-inflammatory drugs binds to NF-kappaB and inhibits its activation: Anticancer effects in vitro and in vivo
    • Zhang, Z.; Huang, L.; Zhao, W.; Rigas, B. Annexin 1 induced by anti-inflammatory drugs binds to NF-kappaB and inhibits its activation: Anticancer effects in vitro and in vivo. Cancer Res. 2010, 70, 2379-2388.
    • (2010) Cancer Res. , vol.70 , pp. 2379-2388
    • Zhang, Z.1    Huang, L.2    Zhao, W.3    Rigas, B.4
  • 17
  • 19
    • 0029814439 scopus 로고    scopus 로고
    • Identification by differential display of annexin-VI, a gene differentially expressed during melanoma progression
    • Francia, G.; Mitchell, S.D.; Moss, S.E.; Hanby, A.M.; Marshall, J.F.; Hart, I.R. Identification by differential display of annexin-VI, a gene differentially expressed during melanoma progression. Cancer Res. 1996, 56, 3855-3858.
    • (1996) Cancer Res. , vol.56 , pp. 3855-3858
    • Francia, G.1    Mitchell, S.D.2    Moss, S.E.3    Hanby, A.M.4    Marshall, J.F.5    Hart, I.R.6
  • 21
    • 41949132295 scopus 로고    scopus 로고
    • A novel C-type lectin from abalone, Haliotis discus discus, agglutinates Vibrio alginolyticus
    • Wang, N.; Whang, I.; Lee, J. A novel C-type lectin from abalone, Haliotis discus discus, agglutinates Vibrio alginolyticus. Dev. Comp. Immunol. 2008, 32, 1034-1040.
    • (2008) Dev. Comp. Immunol. , vol.32 , pp. 1034-1040
    • Wang, N.1    Whang, I.2    Lee, J.3
  • 22
    • 84905841959 scopus 로고    scopus 로고
    • Adenovirus carrying gene coding Haliotis discus discus sialic acid binding lectin induces cancer cell apoptosis
    • Yang, X.; Wu, L.; Duan, X.; Cui, L.; Luo, J.; Li, G. Adenovirus carrying gene coding Haliotis discus discus sialic acid binding lectin induces cancer cell apoptosis. Mar. Drugs 2014, 127, 3994-4004.
    • (2014) Mar. Drugs , vol.127 , pp. 3994-4004
    • Yang, X.1    Wu, L.2    Duan, X.3    Cui, L.4    Luo, J.5    Li, G.6
  • 23
    • 84876467658 scopus 로고    scopus 로고
    • Anti-tumor and anti-viral activities of Galanthus nivalis agglutinin (GNA)-related lectins
    • Wu, L.; Bao, J.K. Anti-tumor and anti-viral activities of Galanthus nivalis agglutinin (GNA)-related lectins. Glycoconj. J. 2013, 30, 269-279.
    • (2013) Glycoconj. J. , vol.30 , pp. 269-279
    • Wu, L.1    Bao, J.K.2
  • 24
    • 84903773018 scopus 로고    scopus 로고
    • Molecular switch role of Akt in Polygonatum odoratum lectin-induced apoptosis and autophagy in human non-small cell lung cancer A549 cells
    • Li, C.; Chen, J.; Lu, B.; Shi, Z.; Wang, H.; Zhang, B.; Zhao, K.; Qi, W.; Bao, J.; Wang, Y. Molecular switch role of Akt in Polygonatum odoratum lectin-induced apoptosis and autophagy in human non-small cell lung cancer A549 cells. PLoS One 2014, 9, e101526.
    • (2014) PLoS One , vol.9 , pp. e101526
    • Li, C.1    Chen, J.2    Lu, B.3    Shi, Z.4    Wang, H.5    Zhang, B.6    Zhao, K.7    Qi, W.8    Bao, J.9    Wang, Y.10
  • 25
    • 67649381654 scopus 로고    scopus 로고
    • Induction of apoptosis by Polygonatum odoratum lectin and its molecular mechanisms in murine fibrosarcoma L929 cells
    • Liu, B.; Zhang, B.; Min, M.W.; Bian, H.J.; Chen, L.F.; Liu, Q.; Bao, J.K. Induction of apoptosis by Polygonatum odoratum lectin and its molecular mechanisms in murine fibrosarcoma L929 cells. Biochim. Biophys. Acta 2009, 1790, 840-844.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 840-844
    • Liu, B.1    Zhang, B.2    Min, M.W.3    Bian, H.J.4    Chen, L.F.5    Liu, Q.6    Bao, J.K.7
  • 26
    • 84907187245 scopus 로고    scopus 로고
    • Polygonatum odoratum lectin induces apoptosis and autophagy via targeting EGFR-mediated Ras-Raf-MEK-ERK pathway in human MCF-7 breast cancer cells
    • Ouyang, L.; Chen, Y.; Wang, X.Y.; Lu, R.F.; Zhang, S.Y.; Tian, M.; Xie, T.; Liu, B.; He, G. Polygonatum odoratum lectin induces apoptosis and autophagy via targeting EGFR-mediated Ras-Raf-MEK-ERK pathway in human MCF-7 breast cancer cells. Phytomedicine 2014, 21, 1658-1665.
    • (2014) Phytomedicine , vol.21 , pp. 1658-1665
    • Ouyang, L.1    Chen, Y.2    Wang, X.Y.3    Lu, R.F.4    Zhang, S.Y.5    Tian, M.6    Xie, T.7    Liu, B.8    He, G.9
  • 27
    • 35648956226 scopus 로고    scopus 로고
    • Effects of Korean mistletoe lectin (Viscum album coloratum) on proliferation and cytokine expression in human peripheral blood mononuclear cells and T-lymphocytes
    • Lyu, S.Y.; Park, W.B. Effects of Korean mistletoe lectin (Viscum album coloratum) on proliferation and cytokine expression in human peripheral blood mononuclear cells and T-lymphocytes. Arch. Pharmacal Res. 2007, 30, 1252-1264.
    • (2007) Arch. Pharmacal Res. , vol.30 , pp. 1252-1264
    • Lyu, S.Y.1    Park, W.B.2
  • 29
    • 84939888480 scopus 로고    scopus 로고
    • Synergistic anticancer effects of lectin and doxorubicin in breast cancer cells
    • Hong, C.E.; Park, A.K.; Lyu, S.Y. Synergistic anticancer effects of lectin and doxorubicin in breast cancer cells. Mol. Cell Biochem. 2014, 94, 225-235.
    • (2014) Mol. Cell Biochem. , vol.94 , pp. 225-235
    • Hong, C.E.1    Park, A.K.2    Lyu, S.Y.3
  • 30
    • 0036480161 scopus 로고    scopus 로고
    • Korean mistletoe lectin-induced apoptosis in hepatocarcinoma cells is associated with inhibition of telomerase via mitochondrial controlled pathway independent of p53
    • Lyu, S.Y.; Choi, S.H.; Park, W.B. Korean mistletoe lectin-induced apoptosis in hepatocarcinoma cells is associated with inhibition of telomerase via mitochondrial controlled pathway independent of p53. Arch. Pharmacal Res. 2002, 25, 93-101.
    • (2002) Arch. Pharmacal Res. , vol.25 , pp. 93-101
    • Lyu, S.Y.1    Choi, S.H.2    Park, W.B.3
  • 31
    • 43049176801 scopus 로고    scopus 로고
    • Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro
    • Seifert, G.; Jesse, P.; Laengler, A.; Tobias Reindl, T.; Lüth, M.; Lobitz, S.; Henze, G.; Prokopa, A.; Lode, H.N. Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro. Cancer Lett. 2008, 264, 218-228.
    • (2008) Cancer Lett. , vol.264 , pp. 218-228
    • Seifert, G.1    Jesse, P.2    Laengler, A.3    Tobias Reindl, T.4    Lüth, M.5    Lobitz, S.6    Henze, G.7    Prokopa, A.8    Lode, H.N.9
  • 33
    • 0034004867 scopus 로고    scopus 로고
    • Recombinant mistletoe lectin (rML) is successful in treating human ovarian cancer cells transplanted into severe combined immunodeficient (SCID) mice
    • Schumacher, U.; Feldhaus, S.; Mengs, U. Recombinant mistletoe lectin (rML) is successful in treating human ovarian cancer cells transplanted into severe combined immunodeficient (SCID) mice. Cancer Lett. 2000, 150, 171-175.
    • (2000) Cancer Lett. , vol.150 , pp. 171-175
    • Schumacher, U.1    Feldhaus, S.2    Mengs, U.3
  • 34
    • 34250890733 scopus 로고    scopus 로고
    • Induction of autophagy by Concanavalin A and its application in anti-tumor therapy
    • Lei, H.Y.; Chang, C.P. Induction of autophagy by Concanavalin A and its application in anti-tumor therapy. Autophagy 2007, 4, 402-404.
    • (2007) Autophagy , vol.4 , pp. 402-404
    • Lei, H.Y.1    Chang, C.P.2
  • 35
    • 58849153349 scopus 로고    scopus 로고
    • Antiproliferative activity and apoptosis-inducing mechanism of Concanavalin A on human melanoma A375 cells
    • Liu, B.; Li, C.Y.; Bian, H.J.; Min, M.W.; Chen, L.F.; Bao, J.K. Antiproliferative activity and apoptosis-inducing mechanism of Concanavalin A on human melanoma A375 cells. Arch. Biochem. Biophys. 2009, 482, 1-6.
    • (2009) Arch. Biochem. Biophys. , vol.482 , pp. 1-6
    • Liu, B.1    Li, C.Y.2    Bian, H.J.3    Min, M.W.4    Chen, L.F.5    Bao, J.K.6
  • 36
    • 65249144593 scopus 로고    scopus 로고
    • Induction of apoptosis by Concanavalin A and its molecular mechanisms in cancer cells
    • Liu, B.; Min, M.W.; Bao, J.K. Induction of apoptosis by Concanavalin A and its molecular mechanisms in cancer cells. Autophagy 2009, 5, 432-433.
    • (2009) Autophagy , vol.5 , pp. 432-433
    • Liu, B.1    Min, M.W.2    Bao, J.K.3
  • 37
    • 63449123137 scopus 로고    scopus 로고
    • Lectin of Concanavalin A as an anti-hepatoma therapeutic agent
    • Lei, H.Y.; Chang, C.P. Lectin of Concanavalin A as an anti-hepatoma therapeutic agent. J. Biomed. Sci. 2009, 16, 10.
    • (2009) J. Biomed. Sci. , vol.16 , pp. 10
    • Lei, H.Y.1    Chang, C.P.2
  • 38
    • 84864436118 scopus 로고    scopus 로고
    • Concanavalin-A-induced autophagy biomarkers requires membrane type-1 matrix metalloproteinase intracellular signaling in glioblastoma cells
    • Pratt, J.; Roy, R.; Annabi, B. Concanavalin-A-induced autophagy biomarkers requires membrane type-1 matrix metalloproteinase intracellular signaling in glioblastoma cells. Glycobiology 2012, 22, 1245-1255.
    • (2012) Glycobiology , vol.22 , pp. 1245-1255
    • Pratt, J.1    Roy, R.2    Annabi, B.3
  • 39
    • 78649835565 scopus 로고    scopus 로고
    • Concanavalin A from an old protein to novel candidate anti-neoplastic drug
    • Li, C.Y.; Xu, H.L.; Liu, B.; Bao, J.K. Concanavalin A from an old protein to novel candidate anti-neoplastic drug. Curr. Mol. Pharmacol. 2010, 5, 123-128.
    • (2010) Curr. Mol. Pharmacol. , vol.5 , pp. 123-128
    • Li, C.Y.1    Xu, H.L.2    Liu, B.3    Bao, J.K.4
  • 41
    • 79958708479 scopus 로고    scopus 로고
    • Calpain activation through galectin-3 inhibition sensitizes prostate cancer cells to cisplatin treatment
    • Wang, Y.; Nangia-Makker, P.; Balan, V.; Hogan, V.; Raz, A. Calpain activation through galectin-3 inhibition sensitizes prostate cancer cells to cisplatin treatment. Cell Death Dis. 2010, 1, e101.
    • (2010) Cell Death Dis. , vol.1 , pp. e101
    • Wang, Y.1    Nangia-Makker, P.2    Balan, V.3    Hogan, V.4    Raz, A.5
  • 42
    • 0033215424 scopus 로고    scopus 로고
    • Restricted receptor segregation into membrane microdomains occurs on human T cells during apoptosis induced by galectin-1
    • Pace, K.E.; Lee, C.; Stewart, P.L.; Baum, L.G. Restricted receptor segregation into membrane microdomains occurs on human T cells during apoptosis induced by galectin-1. J. Immunol. 1999, 163, 3801-3811.
    • (1999) J. Immunol. , vol.163 , pp. 3801-3811
    • Pace, K.E.1    Lee, C.2    Stewart, P.L.3    Baum, L.G.4
  • 43
    • 14844334137 scopus 로고    scopus 로고
    • Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission
    • Matarrese, P.; Tinari, A.; Mormone, E.; Bianco, G.A.; Toscano, M.A.; Ascione, B.; Rabinovich, G.A.; Malorni, W. Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission. J. Biol. Chem. 2005, 280, 6969-6985.
    • (2005) J. Biol. Chem. , vol.280 , pp. 6969-6985
    • Matarrese, P.1    Tinari, A.2    Mormone, E.3    Bianco, G.A.4    Toscano, M.A.5    Ascione, B.6    Rabinovich, G.A.7    Malorni, W.8
  • 44
    • 77449124815 scopus 로고    scopus 로고
    • N- and O-glycans modulate galectin-1 binding, CD45 signaling, and T cell death
    • Earl, L.A.; Bi, S.; Baum, L.G. N- and O-glycans modulate galectin-1 binding, CD45 signaling, and T cell death. J. Biol. Chem. 2010, 285, 2232-2244.
    • (2010) J. Biol. Chem. , vol.285 , pp. 2232-2244
    • Earl, L.A.1    Bi, S.2    Baum, L.G.3
  • 46
    • 84911912245 scopus 로고    scopus 로고
    • Knockdown of galectin-1 suppresses the growth and invasion of osteosarcoma cells through inhibition of the MAPK/ERK pathway
    • Miao, J.H.; Wang, S.Q.; Zhang, M.H.; Yu, F.B.; Zhang, L.; Yu, Z.X.; Kuang, Y. Knockdown of galectin-1 suppresses the growth and invasion of osteosarcoma cells through inhibition of the MAPK/ERK pathway. Oncol. Rep. 2014, 32, 1497-1504.
    • (2014) Oncol. Rep. , vol.32 , pp. 1497-1504
    • Miao, J.H.1    Wang, S.Q.2    Zhang, M.H.3    Yu, F.B.4    Zhang, L.5    Yu, Z.X.6    Kuang, Y.7
  • 47
    • 67549095234 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase targeting by the beta galactoside binding protein cytokine negates akt gene expression and leads aggressive breast cancer cells to apoptotic death
    • Wells, V.; Mallucci, L. Phosphoinositide 3-kinase targeting by the beta galactoside binding protein cytokine negates akt gene expression and leads aggressive breast cancer cells to apoptotic death. Breast Cancer Res. 2009, 11, R2.
    • (2009) Breast Cancer Res. , vol.11 , pp. R2
    • Wells, V.1    Mallucci, L.2
  • 48
    • 0037136419 scopus 로고    scopus 로고
    • Animal lectins: A historical introduction and overview
    • Kilpatrick, D.C. Animal lectins: A historical introduction and overview. Biochim. Biophys. Acta 2002, 1572, 187-197.
    • (2002) Biochim. Biophys. Acta , vol.1572 , pp. 187-197
    • Kilpatrick, D.C.1
  • 49
    • 83355163630 scopus 로고    scopus 로고
    • A serum fucose-binding lectin (DlFBL) from adult Dicentrarchus labrax is expressed in larva and juvenile tissues and contained in eggs
    • Parisi, M.G.; Cammarata, M.; Benenati, G.; Salerno, G.; Mangano, V.; Vizzini, A.; Parrinello, N. A serum fucose-binding lectin (DlFBL) from adult Dicentrarchus labrax is expressed in larva and juvenile tissues and contained in eggs. Cell Tissue Res. 2010, 341, 279-288.
    • (2010) Cell Tissue Res. , vol.341 , pp. 279-288
    • Parisi, M.G.1    Cammarata, M.2    Benenati, G.3    Salerno, G.4    Mangano, V.5    Vizzini, A.6    Parrinello, N.7
  • 50
    • 84897146297 scopus 로고    scopus 로고
    • Exogenous expression of marine lectins DlFBL and SpRBL induces cancer cell apoptosis possibly through PRMT5-E2F-1 pathway
    • Wu, L.; Yang, X.; Duan, X.; Cui, L.; Li, G. Exogenous expression of marine lectins DlFBL and SpRBL induces cancer cell apoptosis possibly through PRMT5-E2F-1 pathway. Sci. Rep. 2014, 4, 4505.
    • (2014) Sci. Rep. , vol.4 , pp. 4505
    • Wu, L.1    Yang, X.2    Duan, X.3    Cui, L.4    Li, G.5
  • 51
    • 84920941027 scopus 로고    scopus 로고
    • Plant lectins, from ancient sugar-binding proteins to emerging anti-cancer drugs in apoptosis and autophagy
    • Jiang, Q.L.; Zhang, S.; Tian, M.; Zhang, S.Y.; Xie, T.; Chen, D.Y.; Chen, Y.J.; He, J.; Liu, J.; Ouyang, L.; et al. Plant lectins, from ancient sugar-binding proteins to emerging anti-cancer drugs in apoptosis and autophagy. Cell Prolif. 2015, 48, 17-28.
    • (2015) Cell Prolif. , vol.48 , pp. 17-28
    • Jiang, Q.L.1    Zhang, S.2    Tian, M.3    Zhang, S.Y.4    Xie, T.5    Chen, D.Y.6    Chen, Y.J.7    He, J.8    Liu, J.9    Ouyang, L.10
  • 52
    • 59849118717 scopus 로고    scopus 로고
    • Autophagy induction in T cell-independent acute hepatitis induced by concanavalin A in SCID/NOD mice
    • Chang, C.P.; Lei, H.Y. Autophagy induction in T cell-independent acute hepatitis induced by concanavalin A in SCID/NOD mice. Int. J. Immunopathol. Pharmacol. 2008, 21, 817-826.
    • (2008) Int. J. Immunopathol. Pharmacol. , vol.21 , pp. 817-826
    • Chang, C.P.1    Lei, H.Y.2
  • 54
    • 70349314681 scopus 로고    scopus 로고
    • Clematis montana lectin, a novel mannose-binding lectin from traditional Chinese medicine with antiviral and apoptosis-inducing activities
    • Peng, H.; Lv, H.; Wang, Y.; Liu, Y.H.; Li, C.Y.; Meng, L.; Chen, F.; Bao, J.K. Clematis montana lectin, a novel mannose-binding lectin from traditional Chinese medicine with antiviral and apoptosis-inducing activities. Peptides 2009, 30, 1805-1815.
    • (2009) Peptides , vol.30 , pp. 1805-1815
    • Peng, H.1    Lv, H.2    Wang, Y.3    Liu, Y.H.4    Li, C.Y.5    Meng, L.6    Chen, F.7    Bao, J.K.8
  • 55
    • 84911449640 scopus 로고    scopus 로고
    • Conformational study reveals amino acid residues essential for hemagglutinating and anti-proliferative activities of Clematis montana lectin
    • Lu, B.; Zhang, B.; Qi, W.; Zhu, Y.; Zhao, Y.; Zhou, N.; Sun, R.; Bao, J.; Wu, C. Conformational study reveals amino acid residues essential for hemagglutinating and anti-proliferative activities of Clematis montana lectin. Acta Biochim. Biophys. Sin. (Shanghai) 2014, 46, 923-934.
    • (2014) Acta Biochim. Biophys. Sin. (Shanghai) , vol.46 , pp. 923-934
    • Lu, B.1    Zhang, B.2    Qi, W.3    Zhu, Y.4    Zhao, Y.5    Zhou, N.6    Sun, R.7    Bao, J.8    Wu, C.9
  • 56
    • 84909951960 scopus 로고    scopus 로고
    • Sclerotium rolfsii Lectin Induces Stronger Inhibition of Proliferation in Human Breast Cancer Cells than Normal Human Mammary Epithelial Cells by Induction of Cell Apoptosis
    • Savanur, M.A.; Eligar, S.M.; Pujari, R.; Chen, C.; Mahajan, P.; Borges, A.; Shastry, P.; Ingle, A.; Kalraiya, R.D.; Swamy, B.M.; et al. Sclerotium rolfsii Lectin Induces Stronger Inhibition of Proliferation in Human Breast Cancer Cells than Normal Human Mammary Epithelial Cells by Induction of Cell Apoptosis. PLoS One 2014, 9, e110107.
    • (2014) PLoS One , vol.9 , pp. e110107
    • Savanur, M.A.1    Eligar, S.M.2    Pujari, R.3    Chen, C.4    Mahajan, P.5    Borges, A.6    Shastry, P.7    Ingle, A.8    Kalraiya, R.D.9    Swamy, B.M.10
  • 57
    • 0036584407 scopus 로고    scopus 로고
    • Evolution of the lectin-complement pathway and its role in innate immunity
    • Fujita, T. Evolution of the lectin-complement pathway and its role in innate immunity. Nat. Rev. Immunol. 2002, 2, 346-353.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 346-353
    • Fujita, T.1
  • 58
    • 84871980316 scopus 로고    scopus 로고
    • In silico analysis of molecular mechanisms of legume lectin-induced apoptosis in cancer cells
    • Shi, Z.; An, N.; Zhao, S.; Li, X.; Bao, J.K.; Yue, B.S. In silico analysis of molecular mechanisms of legume lectin-induced apoptosis in cancer cells. Cell Prolif. 2013, 46, 86-96.
    • (2013) Cell Prolif. , vol.46 , pp. 86-96
    • Shi, Z.1    An, N.2    Zhao, S.3    Li, X.4    Bao, J.K.5    Yue, B.S.6
  • 59
    • 33847754341 scopus 로고    scopus 로고
    • Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model
    • Chang, C.P.; Yang, M.C.; Liu, H.S.; Lin, Y.S.; Lei, H.Y. Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model. Hepatology 2007, 45, 286-296.
    • (2007) Hepatology , vol.45 , pp. 286-296
    • Chang, C.P.1    Yang, M.C.2    Liu, H.S.3    Lin, Y.S.4    Lei, H.Y.5
  • 60
    • 23844534708 scopus 로고    scopus 로고
    • Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells
    • Shalom-Feuerstein, R.; Cooks, T.; Raz, A.; Kloog, Y. Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells. Cancer Res. 2005, 65, 7292-7300.
    • (2005) Cancer Res. , vol.65 , pp. 7292-7300
    • Shalom-Feuerstein, R.1    Cooks, T.2    Raz, A.3    Kloog, Y.4
  • 62
    • 84875242379 scopus 로고    scopus 로고
    • Sensing of cell death by myeloid C-type lectin receptors
    • Sancho, D, Reis e Sousa, C. Sensing of cell death by myeloid C-type lectin receptors. Curr. Opin. Immunol. 2013, 25, 46-52.
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 46-52
    • Sancho, D.1    Reis E Sousa, C.2
  • 64
    • 0033135490 scopus 로고    scopus 로고
    • Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis
    • Bantel, H.; Engels, I.H.; Voelter, W.; Schulze-Osthoff, K.; Wesselborg, S. Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis. Cancer Res. 1999, 59, 2083-2090.
    • (1999) Cancer Res. , vol.59 , pp. 2083-2090
    • Bantel, H.1    Engels, I.H.2    Voelter, W.3    Schulze-Osthoff, K.4    Wesselborg, S.5
  • 65
    • 34250826027 scopus 로고    scopus 로고
    • A novel role for p73 in the regulation of Akt-Foxo1a-Bim signaling and apoptosis induced by the plant lectin
    • Amin, A.R.; Paul, R.K.; Thakur, V.S.; Agarwal, M.L. A novel role for p73 in the regulation of Akt-Foxo1a-Bim signaling and apoptosis induced by the plant lectin, Concanavalin A. Cancer Res. 2007, 67, 5617-5621.
    • (2007) Concanavalin A. Cancer Res. , vol.67 , pp. 5617-5621
    • Amin, A.R.1    Paul, R.K.2    Thakur, V.S.3    Agarwal, M.L.4
  • 66
    • 67649595826 scopus 로고    scopus 로고
    • Apoptosis and cancer: The genesis of a research field
    • Cotter, T.G. Apoptosis and cancer: The genesis of a research field. Nat. Rev. Cancer 2009, 9, 501-507.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 501-507
    • Cotter, T.G.1
  • 67
    • 80052753545 scopus 로고    scopus 로고
    • Quality of life and related dimensions in cancer patients treated with mistletoes extract (Iscador): A meta-analysis
    • Büssing, A.; Raak, C.; Ostermann, T. Quality of life and related dimensions in cancer patients treated with mistletoes extract (Iscador): A meta-analysis. Evid. Based Complement. Altern. Med. 2012, 2012, 219402.
    • (2012) Evid. Based Complement. Altern. Med. , vol.2012 , pp. 219402
    • Büssing, A.1    Raak, C.2    Ostermann, T.3
  • 68
    • 0141857776 scopus 로고    scopus 로고
    • Mistletoe for cancer? A systematic review of randomised clinical trials
    • Ernst, E.; Schmidt, K.; Steuer-Vogt, M.K. Mistletoe for cancer? A systematic review of randomised clinical trials. Int. J. Cancer 2003, 107, 262-267.
    • (2003) Int. J. Cancer , vol.107 , pp. 262-267
    • Ernst, E.1    Schmidt, K.2    Steuer-Vogt, M.K.3
  • 70
    • 77952190319 scopus 로고    scopus 로고
    • Individual patient data meta-analysis of survival and psychosomatic self-regulation from published prospective controlled cohort studies for long-term therapy of breast cancer patients with a mistletoe preparation (Iscador)
    • Ziegler, R.; Grossarth-Maticek, R. Individual patient data meta-analysis of survival and psychosomatic self-regulation from published prospective controlled cohort studies for long-term therapy of breast cancer patients with a mistletoe preparation (Iscador). Evid. Based Complement. Altern. Med. 2010, 7, 157-166.
    • (2010) Evid. Based Complement. Altern. Med. , vol.7 , pp. 157-166
    • Ziegler, R.1    Grossarth-Maticek, R.2
  • 72
    • 84888015440 scopus 로고    scopus 로고
    • Viscum album [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: A randomised clinical trial on overall survival
    • Tröger, W.; Galun, D.; Reif, M.; Schumann, A.; Stanković, N.; Milićević, M. Viscum album [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: A randomised clinical trial on overall survival. Eur. J. Cancer 2013, 49, 3788-3797.
    • (2013) Eur. J. Cancer , vol.49 , pp. 3788-3797
    • Tröger, W.1    Galun, D.2    Reif, M.3    Schumann, A.4    Stanković, N.5    Milićević, M.6
  • 73
    • 84866857650 scopus 로고    scopus 로고
    • Quality of life, immunomodulation and safety of adjuvant mistletoe treatment in patients with gastric carcinoma - A randomized, controlled pilot study
    • Kim, K.C.; Yook, J.H.; Eisenbraun, J.; Kim, B.S.; Huber, R. Quality of life, immunomodulation and safety of adjuvant mistletoe treatment in patients with gastric carcinoma - A randomized, controlled pilot study. BMC Complement. Altern. Med. 2012, 12, 172.
    • (2012) BMC Complement. Altern. Med. , vol.12 , pp. 172
    • Kim, K.C.1    Yook, J.H.2    Eisenbraun, J.3    Kim, B.S.4    Huber, R.5
  • 74
    • 78651322711 scopus 로고    scopus 로고
    • Quality of life in breast cancer patients during chemotherapy and concurrent therapy with a mistletoe extract
    • Eisenbraun, J.; Scheer, R.; Kröz, M.; Schad, F.; Huber, R. Quality of life in breast cancer patients during chemotherapy and concurrent therapy with a mistletoe extract. Phytomedicine 2011, 18, 151-157.
    • (2011) Phytomedicine , vol.18 , pp. 151-157
    • Eisenbraun, J.1    Scheer, R.2    Kröz, M.3    Schad, F.4    Huber, R.5
  • 75
    • 76749158966 scopus 로고    scopus 로고
    • Systematic evaluation of the clinical effects of supportive mistletoe treatment within chemo- and/or radiotherapy protocols and long-term mistletoe application in nonmetastatic colorectal carcinoma: Multicenter, controlled, observational cohort study
    • Friedel, W.E.; Matthes, H.; Bock, P.R.; Zänker, K.S. Systematic evaluation of the clinical effects of supportive mistletoe treatment within chemo- and/or radiotherapy protocols and long-term mistletoe application in nonmetastatic colorectal carcinoma: multicenter, controlled, observational cohort study. J. Soc. Integr. Oncol. 2009, 7, 137-145.
    • (2009) J. Soc. Integr. Oncol. , vol.7 , pp. 137-145
    • Friedel, W.E.1    Matthes, H.2    Bock, P.R.3    Zänker, K.S.4
  • 76
    • 84874936058 scopus 로고    scopus 로고
    • Mistletoe as complementary treatment in patients with advanced non-small-cell lung cancer treated with carboplatin-based combinations: A randomised phase II study
    • Bar-Sela, G.; Wollner, M.; Hammer, L.; Agbarya, A.; Dudnik, E.; Haim, N. Mistletoe as complementary treatment in patients with advanced non-small-cell lung cancer treated with carboplatin-based combinations: A randomised phase II study. Eur. J. Cancer 2013, 49, 1058-1064.
    • (2013) Eur. J. Cancer , vol.49 , pp. 1058-1064
    • Bar-Sela, G.1    Wollner, M.2    Hammer, L.3    Agbarya, A.4    Dudnik, E.5    Haim, N.6
  • 77
    • 40549134157 scopus 로고    scopus 로고
    • Impact of complementary treatment of breast cancer patients with standardized mistletoe extract during aftercare: A controlled multicenter comparative epidemiological cohort study
    • Beuth, J.; Schneider, B.; Schierholz, J.M. Impact of complementary treatment of breast cancer patients with standardized mistletoe extract during aftercare: A controlled multicenter comparative epidemiological cohort study. Anticancer Res. 2008, 28, 523-527.
    • (2008) Anticancer Res. , vol.28 , pp. 523-527
    • Beuth, J.1    Schneider, B.2    Schierholz, J.M.3
  • 80
    • 82655173829 scopus 로고    scopus 로고
    • Galectin-3 - A jack-of-all-trades in cancer
    • Newlaczyl, A.; Yu, L.G. Galectin-3 - A jack-of-all-trades in cancer. Cancer Lett. 2011, 313, 123-810.
    • (2011) Cancer Lett. , vol.313 , pp. 123-810
    • Newlaczyl, A.1    Yu, L.G.2
  • 81
    • 11144241063 scopus 로고    scopus 로고
    • Galectins as modulators of tumour progression
    • Liu, F.T.; Rabinovich, G.A. Galectins as modulators of tumour progression. Nat. Rev. Cancer 2005, 5, 29-41.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 29-41
    • Liu, F.T.1    Rabinovich, G.A.2
  • 82
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • Mizushima, N. Autophagy: Process and function. Genes Dev. 2007, 21, 2861-2873.
    • (2007) Genes Dev. , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 83
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • Levine, B.; Klionsky, D.J. Development by self-digestion: Molecular mechanisms and biological functions of autophagy. Dev. Cell 2004, 6, 463-477.
    • (2004) Dev. Cell , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 84
    • 33750284176 scopus 로고    scopus 로고
    • Autophagy in cancer: Good, bad, or both?
    • Hippert, M.M.; O'Toole, P.S.; Thorburn, A. Autophagy in cancer: Good, bad, or both? Cancer Res. 2006, 66, 9349-9351.
    • (2006) Cancer Res. , vol.66 , pp. 9349-9351
    • Hippert, M.M.1    O'Toole, P.S.2    Thorburn, A.3
  • 86
    • 34147193472 scopus 로고    scopus 로고
    • Cell biology: Autophagy and cancer
    • Levine, B. Cell biology: Autophagy and cancer. Nature 2007, 446, 745-747.
    • (2007) Nature , vol.446 , pp. 745-747
    • Levine, B.1
  • 87
    • 69349094578 scopus 로고    scopus 로고
    • Role and regulation of autophagy in cancer
    • Chen, N.; Karantza-Wadsworth, V. Role and regulation of autophagy in cancer. Biochim. Biophys. Acta 2009, 1793, 1516-1523.
    • (2009) Biochim. Biophys. Acta , vol.1793 , pp. 1516-1523
    • Chen, N.1    Karantza-Wadsworth, V.2
  • 88
    • 84904903972 scopus 로고    scopus 로고
    • Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing Wnt/β-catenin signaling pathway
    • Fu, Y.; Chang, H.; Peng, X.; Bai, Q.; Yi, L.; Zhou, Y.; Zhu, J.; Mi, M. Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing Wnt/β-catenin signaling pathway. PLoS One 2014, 9, e102535.
    • (2014) PLoS One , vol.9 , pp. e102535
    • Fu, Y.1    Chang, H.2    Peng, X.3    Bai, Q.4    Yi, L.5    Zhou, Y.6    Zhu, J.7    Mi, M.8
  • 89
    • 67549101188 scopus 로고    scopus 로고
    • Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
    • Zhang, J.; Ney, P.A. Role of BNIP3 and NIX in cell death, autophagy, and mitophagy. Cell Death Differ. 2009, 16, 939-946.
    • (2009) Cell Death Differ. , vol.16 , pp. 939-946
    • Zhang, J.1    Ney, P.A.2
  • 90
    • 84858145258 scopus 로고    scopus 로고
    • Annexin A5 stimulates autophagy and inhibits endocytosis
    • Ghislat, G.; Aguado, C.; Knecht, E. Annexin A5 stimulates autophagy and inhibits endocytosis. J. Cell Sci. 2012, 125, 92-107.
    • (2012) J. Cell Sci. , vol.125 , pp. 92-107
    • Ghislat, G.1    Aguado, C.2    Knecht, E.3
  • 91
    • 58749105634 scopus 로고    scopus 로고
    • Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway
    • Liu, B.; Cheng, Y.; Zhang, B.; Bian, H.J.; Bao, J.K. Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway. Cancer Lett. 2009, 75, 54-60.
    • (2009) Cancer Lett. , vol.75 , pp. 54-60
    • Liu, B.1    Cheng, Y.2    Zhang, B.3    Bian, H.J.4    Bao, J.K.5
  • 92
    • 84925521913 scopus 로고    scopus 로고
    • Protective role of autophagy and autophagy-related protein 5 in early tumorigenesis
    • Liu, H.; He, Z.; Simon, H.U. Protective role of autophagy and autophagy-related protein 5 in early tumorigenesis. J. Mol. Med. (Berl) 2015, 93, 159-164.
    • (2015) J. Mol. Med. (Berl) , vol.93 , pp. 159-164
    • Liu, H.1    He, Z.2    Simon, H.U.3
  • 93
    • 84899767626 scopus 로고    scopus 로고
    • Mistletoe preparation (Viscum Fraxini-2) as palliative treatment for malignant pleural effusion: A feasibility study with comparison to bleomycin
    • Gaafar, R.; Abdel Rahman, A.R.; Aboulkasem, F.; El Bastawisy, A. Mistletoe preparation (Viscum Fraxini-2) as palliative treatment for malignant pleural effusion: A feasibility study with comparison to bleomycin. Ecancermedicalscience 2014, 8, 424.
    • (2014) Ecancermedicalscience , vol.8 , pp. 424
    • Gaafar, R.1    Abdel Rahman, A.R.2    Aboulkasem, F.3    El Bastawisy, A.4
  • 95
    • 80054853917 scopus 로고    scopus 로고
    • Case reports of sarcoma patients with optimized lectin-oriented mistletoe extract therapy
    • Kirsch, A.; Hajto, T. Case reports of sarcoma patients with optimized lectin-oriented mistletoe extract therapy. J. Altern. Complement. Med. 2011, 17, 973-979.
    • (2011) J. Altern. Complement. Med. , vol.17 , pp. 973-979
    • Kirsch, A.1    Hajto, T.2
  • 96
    • 80052025838 scopus 로고    scopus 로고
    • Safety of higher dosages of Viscum album L. in animals and humans - Systematic review of immune changes and safety parameters
    • Kienle, G.S.; Grugel, R.; Kiene, H. Safety of higher dosages of Viscum album L. in animals and humans - Systematic review of immune changes and safety parameters. BMC Complement. Altern. Med. 2011, 11, 72.
    • (2011) BMC Complement. Altern. Med. , vol.11 , pp. 72
    • Kienle, G.S.1    Grugel, R.2    Kiene, H.3


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