Calpain activation through galectin-3 inhibition sensitizes prostate cancer cells to cisplatin treatment

Cell Death and Disease

Volumn 1, Issue 11, 2010, Pages

  Wang, Y ^a   Nangia Makker, P ^a   Balan, V ^a   Hogan, V ^a   Raz, A ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Calpain; Galectin 3; MCP; Prostate cancer

Indexed keywords

ANDROGEN RECEPTOR; CALPAIN; CISPLATIN; GALECTIN 3; PECTIN; SMALL INTERFERING RNA; ANTINEOPLASTIC AGENT; GCS 100; GCS-100; POLYSACCHARIDE;

APOPTOSIS; ARTICLE; CANCER CELL; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN CLEAVAGE; PROTEINASE INHIBITION; DRUG ANTAGONISM; GENETICS; METABOLISM; PROSTATE TUMOR; RNA INTERFERENCE; TUMOR CELL LINE;

CITRUS;

ANTINEOPLASTIC AGENTS; CALPAIN; CELL LINE, TUMOR; CISPLATIN; GALECTIN 3; HUMANS; MALE; POLYSACCHARIDES; PROSTATIC NEOPLASMS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 79958708479     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2010.79     Document Type: Article

References (40)

1. Eisenberg MA, Blumenstein BA, Crawford ED, Miller G, McLeod DG, Loehrer PJ et al. Bilateral orchiectomy with or without flutamide for metastatic prostate cancer. N Engl J Med 1998; 339: 1036-1042. (Pubitemid 28457865)
2. Inohara H, Akahani S, Raz A. Galectin-3 stimulates cell proliferation. Exp Cell Res 1998; 245: 294-302. (Pubitemid 28565771)
3. O'Driscoll L, Linehan R, Liang YH, Joyce H, Oglesby I, Clynes M. Galectin-3 expression alters adhesion, motility and invasion in a lung cell line (DLKP), in vitro. Anticancer Res 2002; 22: 3117-3125. (Pubitemid 36070082)
4. Nangia-Makker P, Nakahara S, Hogan V, Raz A. Galectin-3 in apoptosis, a novel therapeutic target. J Bioenerg Biomembr 2007; 39: 79-84. (Pubitemid 46877176)
5. Miyazaki J, Hokari R, Kato S, Tsuzuki Y, Kawaguchi A, Nagao S. Increased expression of galectin-3 in primary gastric cancer and the metastatic lymph nodes. Oncol Rep 2002; 9: 1307-1312.
6. Turkoz HK, Oksuz H, Yurdakul Z, Ozcan D. Galectin-3 expression in tumor progression and metastasis of papillary thyroid carcinoma. Endocr Pathol 2008; 19: 92-96.
7. Buttery R, Monaghan H, Salter DM, Sethi T. Galectin-3: differential expression between small-cell and non-small-cell lung cancer. Histopathology 2004; 44: 339-344. (Pubitemid 38491300)
8. Iurisci I, Cumashi A, Sherman AA, Tsvetkov YE, Tinari N, Piccolo E et al. Synthetic inhibitors of galectin-1 and -3 selectively modulate homotypic cell aggregation and tumor cell apoptosis. Anticancer Res 2009; 29: 403-410.
9. Pacis RA, Pilat MJ, Pienta KJ, Wojno K, Raz A, Hogan V et al. Decreased galectin-3 expression in prostate cancer. Prostate 2000; 44: 118-123. (Pubitemid 30419186)
10. Wang Y, Nangia-Makker P, Tait L, Balan V, Hogan V, Pienta KJ et al. Regulation of prostate cancer progression by galectin-3. Am J Pathol 2009; 174: 1515-1523.
11. Ahmed H, Banerjee PP, Vasta GR. Differential expression of galectins in normal, benign and malignant prostate epithelial cells: silencing of galectin-3 expression in prostate cancer by its promoter methylation. Biochem Biophys Res Commun 2007; 358: 241-246. (Pubitemid 46719109)
12. Ahmed H, Cappello F, Rodolico V, Vasta GR. Evidence of heavy methylation in the galectin 3 promoter in early stages of prostate adenocarcinoma: development and validation of a methylated marker for early diagnosis of prostate cancer. Transl Oncol 2009; 2: 146-156.
13. Choi JH, Chun KH, Raz A, Lotan R. Inhibition of N-(4-hydroxyphenyl) retinamide-induced apoptosis in breast cancer cells by galectin-3. Cancer Biol Ther 2004; 3: 447-452. (Pubitemid 41350858)
14. Oishi T, Itamochi H, Kigawa J, Kanamori Y, Shimada M, Takahashi M et al. Galectin-3 may contribute to cisplatin resistance in clear cell carcinoma of the ovary. Int J Gynecol Cancer 2007; 17: 1040-1046. (Pubitemid 47414828)
15. Oka N, Nakahara S, Takenaka Y, Fukumori T, Hogan V, Kanayama HO et al. Galectin-3 inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by activating Akt in human bladder carcinoma cells. Cancer Res 2005; 65: 7546-7553. (Pubitemid 41297223)
16. Fukumori T, Oka N, Takenaka Y, Nangia-Makker P, Elsamman E, Kasai T et al. Galectin-3 regulates mitochondrial stability and antiapoptotic function in response to anticancer drug in prostate cancer. Cancer Res 2006; 66: 3114-3119.
17. Platt D, Raz A. Modulation of the lung colonization of B16-F1 melanoma cells by citrus pectin. J Natl Cancer Inst 1992; 84: 438-442.
18. Inohara H, Raz A. Effects of natural complex carbohydrate (citrus pectin) on murine melanoma cell properties related to galectin-3 functions. Glycoconj J 1994; 11: 527-532.
19. Pienta KJ, Naik H, Akhtar A, Yamazaki K, Replogle TS, Lehr J et al. Inhibition of spontaneous metastasis in a rat prostate cancer model by oral administration of modified citrus pectin. J Natl Cancer Inst 1995; 87: 348-353.
20. Nangia-Makker P, Hogan V, Honjo Y, Baccarini S, Tait L, Bresalier R et al. Inhibition of human cancer cell growth and metastasis in nude mice by oral intake of modified citrus pectin. J Natl Cancer Inst 2002; 94: 1854-1862. (Pubitemid 36104630)
21. Jackson CL, Dreaden TM, Theobald LK, Tran NM, Beal TL, Eid M et al. Pectin induces apoptosis in human prostate cancer cells: correlation of apoptotic function with pectin structure. Glycobiology 2007; 17: 805-819. (Pubitemid 47241818)
22. Chauhan D, Li G, Podar K, Hideshima T, Neri P, He D et al. A novel carbohydrate-based therapeutic GCS-100 overcomes bortezomib resistance and enhances dexamethasoneinduced apoptosis in multiple myeloma cells. Cancer Res 2005; 65: 8350-8358. (Pubitemid 41330600)
23. Nomura T, Yamasaki M, Nomura Y, Mimata H. Expression of the inhibitors of apoptosis proteins in cisplatin-resistant prostate cancer cells. Oncol Rep 2005; 14: 993-997.
24. Strasser A, O'Connor L, Dixit VM. Apoptosis signaling. Annu Rev Biochem 2000; 69: 217-245.
25. Lien YC, Kung HN, Lu KS, Jeng CJ, Chau YP. Involvement of endoplasmic reticulum stress and activation of MAP kinases in beta-lapachone-induced human prostate cancer cell apoptosis. Histol Histopathol 2008; 23: 1299-1308.
26. St John Floyd Jr M, Teahan SJ, Fitzpatrick JM, Watson RW. Differential mechanisms of bicalutamide-induced apoptosis in prostate cell lines. Prostate Cancer Prostatic Dis 2009; 12: 25-33.
27. Vosler PS, Sun D, Wang S, Gao Y, Kintner DB, Signore AP et al. Calcium dysregulation induces apoptosis-inducing factor release: cross-talk between PARP-1- and calpainsignaling pathways. Exp Neurol 2009; 218: 213-220.
28. Yang H, Murthy S, Sarkar FH, Sheng S, Reddy GP, Dou QP. Calpain-mediated androgen receptor breakdown in apoptotic prostate cancer cells. J Cell Physiol 2008; 217: 569-576.
29. Lazebnik YA, Kaufmann SH, Desnoyers S, Poirier GG, Earnshaw WC. Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 1994; 371: 346-347. (Pubitemid 24300618)
30. Oliver FJ, la Rubia G, Rolli V, Ruiz-Ruiz MC, de Murcia G, Murcia JM. Importance of poly (ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant. J Biol Chem 1998; 273: 33533-33539. (Pubitemid 29005737)
31. Bennett V, Gilligan DM. The spectrin-based membrane skeleton and micron-scale organization of the plasma membrane. Annu Rev Cell Biol 1993; 9: 27-66.
32. Yokota M, Saido TC, Kamitani H, Tabuchi S, Satokata I, Watanabe T. Calpain induces proteolysis of neuronal cytoskeleton in ischemic gerbil forebrain. Brain Res 2003; 984: 122-132. (Pubitemid 36976801)
33. Nath R, Huggins M, Glantz SB, Morrow JS, McGinnis K, Nadimpalli R et al. Development and characterization of antibodies specific to caspase-3-produced alpha II-spectrin 120 kDa breakdown product: marker for neuronal apoptosis. Neurochem Int 2000; 37: 351-361. (Pubitemid 30301727)
34. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ. Cancer statistics. CA Cancer J Clin 2007; 57: 43-66.
35. Fukumori T, Takenaka Y, Yoshii T, Kim HR, Hogan V, Inohara H et al. CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis. Cancer Res 2003; 63: 8302-8311. (Pubitemid 37549482)
36. Lin HM, Moon BK, Yu F, Kim HR. Galectin-3 mediates genistein-induced G (2)/M arrest and inhibits apoptosis. Carcinogenesis 2000; 21: 1941-1945.
37. Chauhan D, Li G, Podar K, Hideshima T, Neri P, He D et al. A novel carbohydrate-based therapeutic GCS-100 overcomes bortezomib resistance and enhances dexamethasoneinduced apoptosis in multiple myeloma cells. Cancer Res 2005; 65: 8350-8358. (Pubitemid 41330600)
38. Chao DT, Korsmeyer SJ. Bcl-2 family: regulators of cell death. Annu Rev Immunol 1998; 16: 395-419. (Pubitemid 28183370)
39. Liu L, Xing D, Chen WR, Chen T, Pei Y, Gao X. Calpain-mediated pathway dominates cisplatin-induced apoptosis in human lung adenocarcinoma cells as determined by real-time single cell analysis. Int J Cancer 2008; 122: 2210-2222. (Pubitemid 351542323)
40. Raser KJ, Posner A, Wang KK. Casein zymography: a method to study mu-calpain, m-calpain, and their inhibitory agents. Arch Biochem Biophys 1995; 319: 211-216.