Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway

Cancer Letters

Volumn 275, Issue 1, 2009, Pages 54-60

  Liu, Bo ^a   Cheng, Yan ^b   Zhang, Bo ^a   Bian, He jiao ^a   Bao, Jin ku ^a  

^a SICHUAN UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

A375 cells; Apoptosis; Autophagy; Mitochondria; Polygonatum cyrtonema lectin; ROS

Indexed keywords

CASPASE; CYTOCHROME C; GLUTATHIONE; LECTIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PLANT EXTRACT; POLYGONATUM CYRTONEMA EXTRACT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CONTROLLED STUDY; DEPOLARIZATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MELANOMA; MITOCHONDRION; POLYGONATUM; POLYGONATUM CYRTONEMA; PRIORITY JOURNAL;

APOPTOSIS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; LECTINS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POLYGONATUM; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

POLYGONATUM CYRTONEMA;

EID: 58749105634     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.09.042     Document Type: Article

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