Down-regulation of some miRNAs by degrading their precursors contributes to anti-cancer effect of mistletoe lectin-I

British Journal of Pharmacology

Volumn 162, Issue 2, 2011, Pages 349-364

  Li, Lin Na ^a   Zhang, Hua Dong ^a   Zhi, Run ^a   Yuan, Shou Jun ^a  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

adenomatous polyposis coli; colorectal cancer; miR 135a b; mistletoe lectin I; Wnt signalling pathway

Indexed keywords

BETA CATENIN; CM 1; MICRORNA; RNA PRECURSOR; UNCLASSIFIED DRUG; VISCUM ALBUM LECTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN HEK293; CELL STRAIN HT29; CHINESE; COLON POLYPOSIS; COLORECTAL CANCER; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA DEGRADATION; TRANSCRIPTION TERMINATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HT29 CELLS; HUMANS; MICE; MICE, NUDE; MICRORNAS; MOLECULAR TARGETED THERAPY; NEOPLASMS, EXPERIMENTAL; PHYTOTHERAPY; PLANT LEAVES; PROTEIN ARRAY ANALYSIS; RIBOSOME INACTIVATING PROTEINS, TYPE 2; RNA PRECURSORS; TOXINS, BIOLOGICAL; VISCUM;

EID: 78650321191     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.01042.x     Document Type: Article

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