Neuroblastoma tyrosine kinase signaling networks involve FYN and LYN in endosomes and lipid rafts

PLoS Computational Biology

Volumn 11, Issue 4, 2015, Pages

  Palacios Moreno, Juan ^a   Foltz, Lauren ^a   Guo, Ailan ^b   Stokes, Matthew P ^b   Kuehn, Emily D ^c   George, Lynn ^d   Comb, Michael ^b   Grimes, Mark L ^a  

^a UNIVERSITY OF MONTANA   (United States)

^b CELL SIGNALING TECHNOLOGY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MONTANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; CELL CULTURE; CELL SIGNALING; CELLS; ENZYME ACTIVITY; GRAPH THEORY; PATTERN RECOGNITION; PHOSPHORYLATION; SIGNALING;

ENDOSOMES; INTRACELLULAR LOCALIZATION; LIPID RAFT; NEURAL CRESTS; NEUROBLASTOMAS; PROTEIN PHOSPHORYLATION; RECEPTOR-TYROSINE KINASE; SIGNALING NETWORKS; SIGNALLING PATHWAYS; TYROSINE KINASE;

CHEMICAL ACTIVATION;

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; DETERGENT; EPHRIN RECEPTOR A2; EPHRIN RECEPTOR B3; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FOCAL ADHESION KINASE 1; GUANYLATE KINASE; NEUROTROPHIN RECEPTOR; PDZ PROTEIN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN KINASE FYN; PROTEIN KINASE LYN; PROTEIN KINASE YES; PROTEIN P53; PROTEIN RET; PROTEIN SH2; PROTEIN SH3; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE A; PROTEIN TYROSINE PHOSPHATASE SHP 2; SOMATOMEDIN C RECEPTOR; STEM CELL FACTOR RECEPTOR; FYB PROTEIN, HUMAN; LYN PROTEIN-TYROSINE KINASE; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR PROTEIN;

ANIMAL CELL; ARTICLE; CANCER CELL LINE; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL FRACTIONATION; CELL FUNCTION; CELL MIGRATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; ENDOSOME; HUMAN; HUMAN CELL; HUMAN GENOME; LIPID RAFT; MASS SPECTROMETRY; NEURAL CREST CELL; NEUROBLASTOMA; NEUROBLASTOMA CELL LINE; NONHUMAN; PATTERN RECOGNITION; PHENOTYPE; PHOSPHOPROTEOMICS; POINT MUTATION; PROTEIN DEPHOSPHORYLATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; BIOLOGICAL MODEL; CELL MEMBRANE; COMPUTER SIMULATION; METABOLISM; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL LINE, TUMOR; COMPUTER SIMULATION; ENDOSOMES; HUMANS; MEMBRANE MICRODOMAINS; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; NEUROBLASTOMA; PHOSPHOPROTEINS; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84929485236     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004130     Document Type: Article

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