Ten years of pathway analysis: Current approaches and outstanding challenges

PLoS Computational Biology

Volumn 8, Issue 2, 2012, Pages

  Khatri, Purvesh ^a,b   Sirota, Marina ^a,b   Butte, Atul J ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LUCILE PACKARD CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KNOWLEDGE BASED SYSTEMS; MOLECULAR BIOLOGY; PROTEINS;

'CURRENT; ANALYSIS METHOD; DIFFERENTIALLY EXPRESSED GENE; EXPLANATORY POWER; GAINING INSIGHTS; GENOMICS; PATHWAY ANALYSIS; PROTEOMICS; TECHNOLOGICAL ADVANCES; THREE GENERATIONS;

GENOME;

MITOGEN ACTIVATED PROTEIN KINASE;

CELL SPECIFICITY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE INTERACTION; GENE STRUCTURE; GENETIC ASSOCIATION; GENOMICS; HUMAN; KNOWLEDGE BASE; METHODOLOGY; MICROARRAY ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; REVIEW; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; UPREGULATION; ALGORITHM; ANIMAL; BIOLOGICAL MODEL; BIOLOGY; COMPUTER PROGRAM; GENE EXPRESSION REGULATION; MULTIVARIATE ANALYSIS; REPRODUCIBILITY; STATISTICAL MODEL;

ALGORITHMS; ANIMALS; COMPUTATIONAL BIOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOMICS; HUMANS; MODELS, BIOLOGICAL; MODELS, GENETIC; MODELS, STATISTICAL; MULTIVARIATE ANALYSIS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOFTWARE;

EID: 84861123691     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002375     Document Type: Review

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