SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase

Journal of Cell Biology

Volumn 163, Issue 5, 2003, Pages 999-1010

  Marsh, H Nicholas ^a,h   Dubreuil, Catherine I ^a   Quevedo, Celia ^b   Lee, Anna ^b   Majdan, Marta ^a   Walsh, Gregory S ^a,b   Hausdorff, Sharon ^c   Said, Farid Arab ^d   Zoueva, Olga ^e   Kozlowski, Maya ^e   Siminovitch, Katherine ^f   Neel, Benjamin G ^c   Miller, Freda D ^a,b,g   Kaplan, David R ^a,b,g  

^a MCGILL UNIVERSITY   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^d INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^e HEALTH CANADA   (Canada)

^f MOUNT SINAI HOSPITAL   (Canada)

^g UNIVERSITY OF TORONTO   (Canada)

^h Archemix Corporation   (United States)

Author keywords

Apoptosis; Neurotrophins; NGF; PC12 cells; Sympathetic neurons

Indexed keywords

NERVE GROWTH FACTOR; NERVE GROWTH FACTOR PHOSPHATASE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; DEPHOSPHORYLATION; ENZYME ACTIVITY; MOUSE; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SYMPATHETIC NERVE CELL;

ANIMALS; APOPTOSIS; CARRIER PROTEINS; CELL SURVIVAL; CELLS, CULTURED; ENZYME ACTIVATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED STRAINS; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE GROWTH FACTOR; NEURONS; PC12 CELLS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKA; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION; SYMPATHETIC NERVOUS SYSTEM;

ANIMALIA;

EID: 10744230020     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200309036     Document Type: Article

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