메뉴 건너뛰기




Volumn 29, Issue 11, 2010, Pages 1566-1579

Molecular pathogenesis of peripheral neuroblastic tumors

Author keywords

ALK mutations; Expression profiling; Genetic alterations; Neuroblastoma; Progression; Susceptibility

Indexed keywords

3 [1 (2,6 DICHLORO 3 FLUOROPHENYL)ETHOXY] 5 [1 (4 PIPERIDINYL) 1H PYRAZOL 4 YL] 2 PYRIDINYLAMINE; ANAPLASTIC LYMPHOMA KINASE; NVP TAE 684; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 77949647233     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.518     Document Type: Review
Times cited : (80)

References (132)
  • 1
    • 0142200927 scopus 로고    scopus 로고
    • A case of a diffuse large B-cell lymphoma of plasmablastic type associated with the t(2;5)(p23;q35) chromosome translocation
    • Adam P, Katzenberger T, Seeberger H, Gattenlohner S, Wolf J, Steinlein C, et al. (2003). A case of a diffuse large B-cell lymphoma of plasmablastic type associated with the t(2;5)(p23;q35) chromosome translocation. Am J Surg Pathol 27: 1473-1476.
    • (2003) Am J Surg Pathol , vol.27 , pp. 1473-1476
    • Adam, P.1    Katzenberger, T.2    Seeberger, H.3    Gattenlohner, S.4    Wolf, J.5    Steinlein, C.6
  • 2
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc proteins
    • Adhikary S, Eilers M. (2005). Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 6: 635-645.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 3
    • 0037379890 scopus 로고    scopus 로고
    • Polyalanine expansion and frameshift mutations of the paired-like homeobox gene PHOX2B in Congenital Central Hypoventilation Syndrome
    • Amiel J, Laudier B, Attie-Bitach T, Trang H, de Pontual L, Gener B, et al. (2003). Polyalanine expansion and frameshift mutations of the paired-like homeobox gene PHOX2B in Congenital Central Hypoventilation Syndrome. Nat Genet 33: 459-461.
    • (2003) Nat Genet , vol.33 , pp. 459-461
    • Amiel, J.1    Laudier, B.2    Attie-Bitach, T.3    Trang, H.4    De Pontual, L.5    Gener, B.6
  • 4
    • 33748702052 scopus 로고    scopus 로고
    • Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification
    • Asgharzadeh S, Pique-Regi R, Sposto R, Wang H, Yang Y, Shimada H, et al. (2006). Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification. J Natl Cancer Inst 98: 1193-1203.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 1193-1203
    • Asgharzadeh, S.1    Pique-Regi, R.2    Sposto, R.3    Wang, H.4    Yang, Y.5    Shimada, H.6
  • 7
    • 33644829154 scopus 로고    scopus 로고
    • Stops along the RAS pathway in human genetic disease
    • Bentires-Alj M, Kontaridis MI, Neel BG. (2006). Stops along the RAS pathway in human genetic disease. Nat Med 12: 283-285.
    • (2006) Nat Med , vol.12 , pp. 283-285
    • Bentires-Alj, M.1    Kontaridis, M.I.2    Neel, B.G.3
  • 8
    • 19044380776 scopus 로고    scopus 로고
    • Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma
    • Berwanger B, Hartmann O, Bergmann E, Bernard S, Nielsen D, Krause M, et al. (2002). Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma. Cancer Cell 2: 377-386.
    • (2002) Cancer Cell , vol.2 , pp. 377-386
    • Berwanger, B.1    Hartmann, O.2    Bergmann, E.3    Bernard, S.4    Nielsen, D.5    Krause, M.6
  • 9
    • 38149121417 scopus 로고    scopus 로고
    • Behavioral and neurochemical alterations in mice deficient in anaplastic lymphoma kinase suggest therapeutic potential for psychiatric indications
    • Bilsland JG, Wheeldon A, Mead A, Znamenskiy P, Almond S, Waters KA, et al. (2008). Behavioral and neurochemical alterations in mice deficient in anaplastic lymphoma kinase suggest therapeutic potential for psychiatric indications. Neuropsychopharmacology 33: 685-700.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 685-700
    • Bilsland, J.G.1    Wheeldon, A.2    Mead, A.3    Znamenskiy, P.4    Almond, S.5    Waters, K.A.6
  • 11
    • 43449122453 scopus 로고    scopus 로고
    • In neuroblastic tumours, Schwann cells do not harbour the genetic alterations of neuroblasts but may nevertheless share the same clonal origin
    • Bourdeaut F, Ribeiro A, Paris R, Pierron G, Couturier J, Peuchmaur M, et al. (2008). In neuroblastic tumours, Schwann cells do not harbour the genetic alterations of neuroblasts but may nevertheless share the same clonal origin. Oncogene 27: 3066-3071.
    • (2008) Oncogene , vol.27 , pp. 3066-3071
    • Bourdeaut, F.1    Ribeiro, A.2    Paris, R.3    Pierron, G.4    Couturier, J.5    Peuchmaur, M.6
  • 13
    • 0037366067 scopus 로고    scopus 로고
    • Neuroblastoma: Biological insights into a clinical enigma
    • Brodeur GM. (2003). Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 3: 203-216.
    • (2003) Nat Rev Cancer , vol.3 , pp. 203-216
    • Brodeur, G.M.1
  • 14
    • 0027239723 scopus 로고
    • Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment
    • Brodeur GM, Pritchard J, Berthold F, Carlsen NL, Castel V, Castelberry RP, et al. (1993). Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol 11: 1466-1477.
    • (1993) J Clin Oncol , vol.11 , pp. 1466-1477
    • Brodeur, G.M.1    Pritchard, J.2    Berthold, F.3    Carlsen, N.L.4    Castel, V.5    Castelberry, R.P.6
  • 16
    • 58149289668 scopus 로고    scopus 로고
    • High incidence of DNA mutations and gene amplifications of the ALK gene in advanced sporadic neuroblastoma tumours
    • Caren H, Abel F, Kogner P, Martinsson T. (2008). High incidence of DNA mutations and gene amplifications of the ALK gene in advanced sporadic neuroblastoma tumours. Biochem J 416: 153-159.
    • (2008) Biochem J , vol.416 , pp. 153-159
    • Caren, H.1    Abel, F.2    Kogner, P.3    Martinsson, T.4
  • 17
    • 0035158966 scopus 로고    scopus 로고
    • Chromosome bands 1p35-36 contain two distinct neuroblastoma tumor suppressor loci, one of which is imprinted
    • Caron H, Spieker N, Godfried M, Veenstra M, van Sluis P, de Kraker J, et al. (2001). Chromosome bands 1p35-36 contain two distinct neuroblastoma tumor suppressor loci, one of which is imprinted. Genes Chromosomes Cancer 30: 168-174.
    • (2001) Genes Chromosomes Cancer , vol.30 , pp. 168-174
    • Caron, H.1    Spieker, N.2    Godfried, M.3    Veenstra, M.4    Van Sluis, P.5    De Kraker, J.6
  • 18
    • 0028128737 scopus 로고
    • Recurrent 1;17 translocations in human neuroblastoma reveal nonhomologous mitotic recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity
    • Caron H, van Sluis P, van Roy N, de Kraker J, Speleman F, Voute PA, et al. (1994). Recurrent 1;17 translocations in human neuroblastoma reveal nonhomologous mitotic recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity. Am J Hum Genet 55: 341-347.
    • (1994) Am J Hum Genet , vol.55 , pp. 341-347
    • Caron, H.1    Van Sluis, P.2    Van Roy, N.3    De Kraker, J.4    Speleman, F.5    Voute, P.A.6
  • 19
    • 33845965035 scopus 로고    scopus 로고
    • High-resolution analysis of allelic imbalance in neuroblastoma cell lines by single nucleotide polymorphism arrays
    • Carr J, Bown NP, Case MC, Hall AG, Lunec J, Tweddle DA. (2007). High-resolution analysis of allelic imbalance in neuroblastoma cell lines by single nucleotide polymorphism arrays. Cancer Genet Cytogenet 172: 127-138.
    • (2007) Cancer Genet Cytogenet , vol.172 , pp. 127-138
    • Carr, J.1    Bown, N.P.2    Case, M.C.3    Hall, A.G.4    Lunec, J.5    Tweddle, D.A.6
  • 20
    • 0027080193 scopus 로고
    • Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene
    • Charron J, Malynn BA, Fisher P, Stewart V, Jeannotte L, Goff SP, et al. (1992). Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene. Genes Dev 6: 2248-2257.
    • (1992) Genes Dev , vol.6 , pp. 2248-2257
    • Charron, J.1    Malynn, B.A.2    Fisher, P.3    Stewart, V.4    Jeannotte, L.5    Goff, S.P.6
  • 21
    • 9144245019 scopus 로고    scopus 로고
    • CDNA array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuro-blastoma
    • Chen QR, Bilke S, Wei JS, Whiteford CC, Cenacchi N, Krasnoselsky AL, et al. (2004). cDNA array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuro-blastoma. BMC Genomics 5: 70.
    • (2004) BMC Genomics , vol.5 , pp. 70
    • Chen, Q.R.1    Bilke, S.2    Wei, J.S.3    Whiteford, C.C.4    Cenacchi, N.5    Krasnoselsky, A.L.6
  • 22
  • 23
    • 35148877172 scopus 로고    scopus 로고
    • Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma
    • Chesler L, Goldenberg DD, Seales IT, Satchi-Fainaro R, Grimmer M, Collins R, et al. (2007). Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma. Cancer Res 67: 9435-9442.
    • (2007) Cancer Res , vol.67 , pp. 9435-9442
    • Chesler, L.1    Goldenberg, D.D.2    Seales, I.T.3    Satchi-Fainaro, R.4    Grimmer, M.5    Collins, R.6
  • 24
    • 0037372285 scopus 로고    scopus 로고
    • NPM-ALK transgenic mice spontaneously develop T-cell lympho-mas and plasma cell tumors
    • Chiarle R, Gong JZ, Guasparri I, Pesci A, Cai J, Liu J, et al. (2003). NPM-ALK transgenic mice spontaneously develop T-cell lympho-mas and plasma cell tumors. Blood 101: 1919-1927.
    • (2003) Blood , vol.101 , pp. 1919-1927
    • Chiarle, R.1    Gong, J.Z.2    Guasparri, I.3    Pesci, A.4    Cai, J.5    Liu, J.6
  • 26
    • 58249093955 scopus 로고    scopus 로고
    • The International Neuroblastoma Risk Group (INRG) classification system: An INRG Task Force report
    • Cohn SL, Pearson AD, London WB, Monclair T, Ambros PF, Brodeur GM, et al. (2009). The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report. J Clin Oncol 27: 289-297.
    • (2009) J Clin Oncol , vol.27 , pp. 289-297
    • Cohn, S.L.1    Pearson, A.D.2    London, W.B.3    Monclair, T.4    Ambros, P.F.5    Brodeur, G.M.6
  • 28
    • 56049088767 scopus 로고    scopus 로고
    • Clinical and molecular aspects of RAS related disorders
    • Denayer E, de Ravel T, Legius E. (2008). Clinical and molecular aspects of RAS related disorders. J Med Genet 45: 695-703.
    • (2008) J Med Genet , vol.45 , pp. 695-703
    • Denayer, E.1    De Ravel, T.2    Legius, E.3
  • 30
    • 54349087788 scopus 로고    scopus 로고
    • Myc's broad reach
    • Eilers M, Eisenman RN. (2008). Myc's broad reach. Genes Dev 22: 2755-2766.
    • (2008) Genes Dev , vol.22 , pp. 2755-2766
    • Eilers, M.1    Eisenman, R.N.2
  • 31
    • 0015014530 scopus 로고
    • A proposed staging for children with neuroblastoma
    • Children's cancer study group A
    • Evans AE, D'Angio GJ, Randolph J. (1971). A proposed staging for children with neuroblastoma. Children's cancer study group A. Cancer 27: 374-378.
    • (1971) Cancer , vol.27 , pp. 374-378
    • Evans, A.E.1    D'Angio, G.J.2    Randolph, J.3
  • 32
    • 50249123931 scopus 로고    scopus 로고
    • Characterization of amplicons in neuroblastoma: High-resolution mapping using DNA microarrays, relationship with outcome, and identification of overexpressed genes
    • Fix A, Lucchesi C, Ribeiro A, Lequin D, Pierron G, Schleiermacher G, et al. (2008). Characterization of amplicons in neuroblastoma: high-resolution mapping using DNA microarrays, relationship with outcome, and identification of overexpressed genes. Genes Chromosomes Cancer 47: 819-834.
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 819-834
    • Fix, A.1    Lucchesi, C.2    Ribeiro, A.3    Lequin, D.4    Pierron, G.5    Schleiermacher, G.6
  • 33
    • 2542595412 scopus 로고    scopus 로고
    • High-resolution mapping of amplicons of the short arm of chromosome 1 in two neuroblastoma tumors by microarray-based comparative genomic hybridization
    • Fix A, Peter M, Pierron G, Aurias A, Delattre O, Janoueix-Lerosey I. (2004). High-resolution mapping of amplicons of the short arm of chromosome 1 in two neuroblastoma tumors by microarray-based comparative genomic hybridization. Genes Chromosomes Cancer 40: 266-270.
    • (2004) Genes Chromosomes Cancer , vol.40 , pp. 266-270
    • Fix, A.1    Peter, M.2    Pierron, G.3    Aurias, A.4    Delattre, O.5    Janoueix-Lerosey, I.6
  • 34
    • 52949154642 scopus 로고    scopus 로고
    • High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma
    • Fredlund E, Ringner M, Maris JM, Pahlman S. (2008). High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma. Proc Natl Acad Sci USA 105: 14094-14099.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14094-14099
    • Fredlund, E.1    Ringner, M.2    Maris, J.M.3    Pahlman, S.4
  • 35
    • 39049191809 scopus 로고    scopus 로고
    • Exploration of human miRNA target genes in neuronal differentiation
    • Fukuda Y, Kawasaki H, Taira K. (2005). Exploration of human miRNA target genes in neuronal differentiation. Nucleic Acids Symp Ser (Oxf) 49: 341-342.
    • (2005) Nucleic Acids Symp ser (Oxf) , vol.49 , pp. 341-342
    • Fukuda, Y.1    Kawasaki, H.2    Taira, K.3
  • 36
    • 33846110366 scopus 로고    scopus 로고
    • Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK
    • Galkin AV, Melnick JS, Kim S, Hood TL, Li N, Li L, et al. (2007). Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK. Proc Natl Acad Sci USA 104: 270-275.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 270-275
    • Galkin, A.V.1    Melnick, J.S.2    Kim, S.3    Hood, T.L.4    Li, N.5    Li, L.6
  • 37
    • 35648978472 scopus 로고    scopus 로고
    • Genome-wide analysis of neuroblastomas using high-density single nucleotide polymorphism arrays
    • George RE, Attiyeh EF, Li S, Moreau LA, Neuberg D, Li C, et al. (2007). Genome-wide analysis of neuroblastomas using high-density single nucleotide polymorphism arrays. PLoS ONE 2: e255.
    • (2007) PLoS ONE , vol.2
    • George, R.E.1    Attiyeh, E.F.2    Li, S.3    Moreau, L.A.4    Neuberg, D.5    Li, C.6
  • 39
    • 54049120220 scopus 로고    scopus 로고
    • Activating mutations in ALK provide a therapeutic target in neuroblastoma
    • George RE, Sanda T, Hanna M, Frohling S, Luther II W, Zhang J, et al. (2008). Activating mutations in ALK provide a therapeutic target in neuroblastoma. Nature 455: 975-978.
    • (2008) Nature , vol.455 , pp. 975-978
    • George, R.E.1    Sanda, T.2    Hanna, M.3    Frohling, S.4    Luther Ii, W.5    Zhang, J.6
  • 42
    • 41449105183 scopus 로고    scopus 로고
    • Effectiveness of screening for neuroblastoma at 6 months of age: A retrospective population-based cohort study
    • Hiyama E, Iehara T, Sugimoto T, Fukuzawa M, Hayashi Y, Sasaki F, et al. (2008). Effectiveness of screening for neuroblastoma at 6 months of age: a retrospective population-based cohort study. Lancet 371: 1173-1180.
    • (2008) Lancet , vol.371 , pp. 1173-1180
    • Hiyama, E.1    Iehara, T.2    Sugimoto, T.3    Fukuzawa, M.4    Hayashi, Y.5    Sasaki, F.6
  • 43
  • 46
    • 0024803497 scopus 로고
    • Coamplifica-tion of the L-myc and N-myc oncogenes in a neuroblastoma cell line
    • Jinbo T, Iwamura Y, Kaneko M, Sawaguchi S. (1989). Coamplifica-tion of the L-myc and N-myc oncogenes in a neuroblastoma cell line. Jpn J Cancer Res 80: 299-301.
    • (1989) Jpn J Cancer Res , vol.80 , pp. 299-301
    • Jinbo, T.1    Iwamura, Y.2    Kaneko, M.3    Sawaguchi, S.4
  • 47
    • 0037108268 scopus 로고    scopus 로고
    • N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
    • Knoepfler PS, Cheng PF, Eisenman RN. (2002). N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev 16: 2699-2712.
    • (2002) Genes Dev , vol.16 , pp. 2699-2712
    • Knoepfler, P.S.1    Cheng, P.F.2    Eisenman, R.N.3
  • 51
    • 34249946434 scopus 로고    scopus 로고
    • The interplay between microRNAs and the neuro-trophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells
    • Laneve P, Di Marcotullio L, Gioia U, Fiori ME, Ferretti E, Gulino A, et al. (2007). The interplay between microRNAs and the neuro-trophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells. Proc Natl Acad Sci USA 104: 7957-7962.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 7957-7962
    • Laneve, P.1    Di Marcotullio, L.2    Gioia, U.3    Fiori, M.E.4    Ferretti, E.5    Gulino, A.6
  • 52
    • 0035876142 scopus 로고    scopus 로고
    • Comprehensive genetic and histopathologic study reveals three types of neuroblastoma tumors
    • Lastowska M, Cullinane C, Variend S, Cotterill S, Bown N, O'Neill S, et al. (2001). Comprehensive genetic and histopathologic study reveals three types of neuroblastoma tumors. J Clin Oncol 19: 3080-3090.
    • (2001) J Clin Oncol , vol.19 , pp. 3080-3090
    • Lastowska, M.1    Cullinane, C.2    Variend, S.3    Cotterill, S.4    Bown, N.5    O'Neill, S.6
  • 53
    • 39849099343 scopus 로고    scopus 로고
    • Deregulated Wnt/beta-catenin program in high-risk neuroblastomas without MYCN amplification
    • Liu X, Mazanek P, Dam V, Wang Q, Zhao H, Guo R, et al. (2008). Deregulated Wnt/beta-catenin program in high-risk neuroblastomas without MYCN amplification. Oncogene 27: 1478-1488.
    • (2008) Oncogene , vol.27 , pp. 1478-1488
    • Liu, X.1    Mazanek, P.2    Dam, V.3    Wang, Q.4    Zhao, H.5    Guo, R.6
  • 54
    • 0021201236 scopus 로고
    • Cellular DNA content as a predictor of response to chemotherapy in infants with unresectable neuroblastoma
    • Look AT, Hayes FA, Nitschke R, McWilliams NB, Green AA. (1984). Cellular DNA content as a predictor of response to chemotherapy in infants with unresectable neuroblastoma. N Engl J Med 311: 231-235.
    • (1984) N Engl J Med , vol.311 , pp. 231-235
    • Look, A.T.1    Hayes, F.A.2    Nitschke, R.3    McWilliams, N.B.4    Green, A.A.5
  • 55
    • 0025979843 scopus 로고
    • Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: A Pediatric Oncology Group study
    • Look AT, Hayes FA, Shuster JJ, Douglass EC, Castleberry RP, Bowman LC, et al. (1991). Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study. J Clin Oncol 9: 581-591.
    • (1991) J Clin Oncol , vol.9 , pp. 581-591
    • Look, A.T.1    Hayes, F.A.2    Shuster, J.J.3    Douglass, E.C.4    Castleberry, R.P.5    Bowman, L.C.6
  • 56
    • 0029947714 scopus 로고    scopus 로고
    • Double-strand break repair in the absence of RAD51 in yeast: A possible role for break-induced DNA replication
    • Malkova A, Ivanov EL, Haber JE. (1996). Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced DNA replication. Proc Natl Acad Sci USA 93: 7131-7136.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7131-7136
    • Malkova, A.1    Ivanov, E.L.2    Haber, J.E.3
  • 59
  • 60
    • 41449106522 scopus 로고    scopus 로고
    • Screening for neuroblastoma: A resurrected idea?
    • Maris JM, Woods WG. (2008). Screening for neuroblastoma: a resurrected idea? Lancet 371: 1142-1143.
    • (2008) Lancet , vol.371 , pp. 1142-1143
    • Maris, J.M.1    Woods, W.G.2
  • 61
    • 33744827949 scopus 로고    scopus 로고
    • PHOX2B analysis in non-syndromic neuroblastoma cases shows novel mutations and genotype-phenotype associations
    • McConville C, Reid S, Baskcomb L, Douglas J, Rahman N. (2006). PHOX2B analysis in non-syndromic neuroblastoma cases shows novel mutations and genotype-phenotype associations. Am J Med Genet A 140: 1297-1301.
    • (2006) Am J Med Genet A , vol.140 , pp. 1297-1301
    • McConville, C.1    Reid, S.2    Baskcomb, L.3    Douglas, J.4    Rahman, N.5
  • 62
    • 44849126091 scopus 로고    scopus 로고
    • Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors
    • McDermott U, Iafrate AJ, Gray NS, Shioda T, Classon M, Maheswaran S, et al. (2008). Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors. Cancer Res 68: 3389-3395.
    • (2008) Cancer Res , vol.68 , pp. 3389-3395
    • McDermott, U.1    Iafrate, A.J.2    Gray, N.S.3    Shioda, T.4    Classon, M.5    Maheswaran, S.6
  • 63
    • 34249676964 scopus 로고    scopus 로고
    • Chronic myeloid leukaemia as a model of disease evolution in human cancer
    • Melo JV, Barnes DJ. (2007). Chronic myeloid leukaemia as a model of disease evolution in human cancer. Nat Rev Cancer 7: 441-453.
    • (2007) Nat Rev Cancer , vol.7 , pp. 441-453
    • Melo, J.V.1    Barnes, D.J.2
  • 64
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with MYC
    • Meyer N, Penn LZ. (2008). Reflecting on 25 years with MYC. Nat Rev Cancer 8: 976-990.
    • (2008) Nat Rev Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 66
    • 0037194586 scopus 로고    scopus 로고
    • Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines
    • Miyake I, Hakomori Y, Shinohara A, Gamou T, Saito M, Iwamatsu A, et al. (2002). Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines. Oncogene 21: 5823-5834.
    • (2002) Oncogene , vol.21 , pp. 5823-5834
    • Miyake, I.1    Hakomori, Y.2    Shinohara, A.3    Gamou, T.4    Saito, M.5    Iwamatsu, A.6
  • 68
    • 58249093954 scopus 로고    scopus 로고
    • The International Neuroblastoma Risk Group (INRG) staging system: An INRG Task Force report
    • Monclair T, Brodeur GM, Ambros PF, Brisse HJ, Cecchetto G, Holmes K, et al. (2009). The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report. J Clin Oncol 27: 298-303.
    • (2009) J Clin Oncol , vol.27 , pp. 298-303
    • Monclair, T.1    Brodeur, G.M.2    Ambros, P.F.3    Brisse, H.J.4    Cecchetto, G.5    Holmes, K.6
  • 70
    • 0347503601 scopus 로고    scopus 로고
    • Identification and high-resolution mapping of a constitutional 11q deletion in an infant with multifocal neuroblastoma
    • Mosse Y, Greshock J, King A, Khazi D, Weber BL, Maris JM. (2003). Identification and high-resolution mapping of a constitutional 11q deletion in an infant with multifocal neuroblastoma. Lancet Oncol 4: 769-771.
    • (2003) Lancet Oncol , vol.4 , pp. 769-771
    • Mosse, Y.1    Greshock, J.2    King, A.3    Khazi, D.4    Weber, B.L.5    Maris, J.M.6
  • 71
    • 34548788439 scopus 로고    scopus 로고
    • Neuroblastomas have distinct genomic DNA profiles that predict clinical phenotype and regional gene expression
    • Mosse YP, Diskin SJ, Wasserman N, Rinaldi K, Attiyeh EF, Cole K, et al. (2007). Neuroblastomas have distinct genomic DNA profiles that predict clinical phenotype and regional gene expression. Genes Chromosomes Cancer 46: 936-949.
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 936-949
    • Mosse, Y.P.1    Diskin, S.J.2    Wasserman, N.3    Rinaldi, K.4    Attiyeh, E.F.5    Cole, K.6
  • 74
    • 54049094708 scopus 로고    scopus 로고
    • Identification of ALK as a major familial neuroblas-toma predisposition gene
    • Mosse YP, Laudenslager M, Longo L, Cole KA, Wood A, Attiyeh EF, et al. (2008). Identification of ALK as a major familial neuroblas-toma predisposition gene. Nature 455: 930-935.
    • (2008) Nature , vol.455 , pp. 930-935
    • Mosse, Y.P.1    Laudenslager, M.2    Longo, L.3    Cole, K.A.4    Wood, A.5    Attiyeh, E.F.6
  • 75
    • 33746947883 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage
    • Mourali J, Benard A, Lourenco FC, Monnet C, Greenland C, Moog-Lutz C, et al. (2006). Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage. Mol Cell Biol 26: 6209-6222.
    • (2006) Mol Cell Biol , vol.26 , pp. 6209-6222
    • Mourali, J.1    Benard, A.2    Lourenco, F.C.3    Monnet, C.4    Greenland, C.5    Moog-Lutz, C.6
  • 76
    • 42149180583 scopus 로고    scopus 로고
    • Birth-related characteristics, congenital malformation, maternal reproductive history and neuroblastoma: The ESCALE study (SFCE)
    • Munzer C, Menegaux F, Lacour B, Valteau-Couanet D, Michon J, Coze C, et al. (2008). Birth-related characteristics, congenital malformation, maternal reproductive history and neuroblastoma: the ESCALE study (SFCE). Int J Cancer 122: 2315-2321.
    • (2008) Int J Cancer , vol.122 , pp. 2315-2321
    • Munzer, C.1    Menegaux, F.2    Lacour, B.3    Valteau-Couanet, D.4    Michon, J.5    Coze, C.6
  • 77
    • 33750963337 scopus 로고    scopus 로고
    • Customized oligonucleotide microarray gene expression-based classification of neuroblastoma patients outperforms current clinical risk stratification
    • Oberthuer A, Berthold F, Warnat P, Hero B, Kahlert Y, Spitz R, et al. (2006). Customized oligonucleotide microarray gene expression-based classification of neuroblastoma patients outperforms current clinical risk stratification. J Clin Oncol 24: 5070-5078.
    • (2006) J Clin Oncol , vol.24 , pp. 5070-5078
    • Oberthuer, A.1    Berthold, F.2    Warnat, P.3    Hero, B.4    Kahlert, Y.5    Spitz, R.6
  • 78
    • 20244385561 scopus 로고    scopus 로고
    • Expression profiling using a tumor-specific cDNA microarray predicts the prognosis of intermediate risk neuroblasto-mas
    • Ohira M, Oba S, Nakamura Y, Isogai E, Kaneko S, Nakagawa A, et al. (2005). Expression profiling using a tumor-specific cDNA microarray predicts the prognosis of intermediate risk neuroblasto-mas. Cancer Cell 7: 337-350.
    • (2005) Cancer Cell , vol.7 , pp. 337-350
    • Ohira, M.1    Oba, S.2    Nakamura, Y.3    Isogai, E.4    Kaneko, S.5    Nakagawa, A.6
  • 79
    • 0141593498 scopus 로고    scopus 로고
    • ALK-positive plasmablastic B-cell lymphoma with expression of the NPM-ALK fusion transcript: Report of 2 cases
    • Onciu M, Behm FG, Downing JR, Shurtleff SA, Raimondi SC, Ma Z, et al. (2003). ALK-positive plasmablastic B-cell lymphoma with expression of the NPM-ALK fusion transcript: report of 2 cases. Blood 102: 2642-2644.
    • (2003) Blood , vol.102 , pp. 2642-2644
    • Onciu, M.1    Behm, F.G.2    Downing, J.R.3    Shurtleff, S.A.4    Raimondi, S.C.5    Ma, Z.6
  • 81
    • 66949152073 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase: Signalling in development and disease
    • Palmer RH, Vernersson E, Grabbe C, Hallberg B. (2009). Anaplastic lymphoma kinase: signalling in development and disease. Biochem J 420: 345-361.
    • (2009) Biochem J , vol.420 , pp. 345-361
    • Palmer, R.H.1    Vernersson, E.2    Grabbe, C.3    Hallberg, B.4
  • 82
    • 70349733112 scopus 로고    scopus 로고
    • Mutation-independent anaplastic lymphoma kinase over-expression in poor prognosis neuroblastoma patients
    • Passoni L, Longo L, Collini P, Coluccia AM, Bozzi F, Podda M, et al. (2009). Mutation-independent anaplastic lymphoma kinase over-expression in poor prognosis neuroblastoma patients. Cancer Res 69: 7338-7346.
    • (2009) Cancer Res , vol.69 , pp. 7338-7346
    • Passoni, L.1    Longo, L.2    Collini, P.3    Coluccia, A.M.4    Bozzi, F.5    Podda, M.6
  • 83
    • 0033609337 scopus 로고    scopus 로고
    • The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives
    • Pattyn A, Morin X, Cremer H, Goridis C, Brunet JF. (1999). The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature 399: 366-370.
    • (1999) Nature , vol.399 , pp. 366-370
    • Pattyn, A.1    Morin, X.2    Cremer, H.3    Goridis, C.4    Brunet, J.F.5
  • 84
    • 0035283744 scopus 로고    scopus 로고
    • Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11q deletion in tumors lacking MYCN amplification
    • Plantaz D, Vandesompele J, Van Roy N, Lastowska M, Bown N, Combaret V, et al. (2001). Comparative genomic hybridization (CGH) analysis of stage 4 neuroblastoma reveals high frequency of 11q deletion in tumors lacking MYCN amplification. Int J Cancer 91: 680-686.
    • (2001) Int J Cancer , vol.91 , pp. 680-686
    • Plantaz, D.1    Vandesompele, J.2    Van Roy, N.3    Lastowska, M.4    Bown, N.5    Combaret, V.6
  • 86
    • 36849065315 scopus 로고    scopus 로고
    • Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
    • Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, et al. (2007). Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 131: 1190-1203.
    • (2007) Cell , vol.131 , pp. 1190-1203
    • Rikova, K.1    Guo, A.2    Zeng, Q.3    Possemato, A.4    Yu, J.5    Haack, H.6
  • 87
    • 58149114635 scopus 로고    scopus 로고
    • Neuroblastoma-remembering the three physicians who described it a century ago: James Homer Wright, William Pepper, and Robert Hutchison
    • Rothenberg AB, Berdon WE, D'Angio GJ, Yamashiro DJ, Cowles RA. (2009). Neuroblastoma-remembering the three physicians who described it a century ago: James Homer Wright, William Pepper, and Robert Hutchison. Pediatr Radiol 39: 155-160.
    • (2009) Pediatr Radiol , vol.39 , pp. 155-160
    • Rothenberg, A.B.1    Berdon, W.E.2    D'Angio, G.J.3    Yamashiro, D.J.4    Cowles, R.A.5
  • 88
    • 0242575113 scopus 로고    scopus 로고
    • Abnormal constitutional karyotypes in patients with neuroblastoma: A report of four new cases and review of 47 others in the literature
    • Satge D, Moore SW, Stiller CA, Niggli FK, Pritchard-Jones K, Bown N, et al. (2003). Abnormal constitutional karyotypes in patients with neuroblastoma: a report of four new cases and review of 47 others in the literature. Cancer Genet Cytogenet 147: 89-98.
    • (2003) Cancer Genet Cytogenet , vol.147 , pp. 89-98
    • Satge, D.1    Moore, S.W.2    Stiller, C.A.3    Niggli, F.K.4    Pritchard-Jones, K.5    Bown, N.6
  • 90
    • 18844382646 scopus 로고    scopus 로고
    • Stepwise occurrence of a complex unbalanced translocation in neuroblastoma leading to insertion of a telomere sequence and late chromosome 17q gain
    • Schleiermacher G, Bourdeaut F, Combaret V, Picrron G, Raynal V, Aurias A, et al. (2005). Stepwise occurrence of a complex unbalanced translocation in neuroblastoma leading to insertion of a telomere sequence and late chromosome 17q gain. Oncogene 24: 3377-3384.
    • (2005) Oncogene , vol.24 , pp. 3377-3384
    • Schleiermacher, G.1    Bourdeaut, F.2    Combaret, V.3    Picrron, G.4    Raynal, V.5    Aurias, A.6
  • 91
    • 0037308543 scopus 로고    scopus 로고
    • Combined 24-color karyotyping and comparative genomic hybridization analysis indicates predominant rearrangements of early replicating chromosome regions in neuroblastoma
    • Schleiermacher G, Janoueix-Lerosey I, Combaret V, Derre J, Couturier J, Aurias A, et al. (2003). Combined 24-color karyotyping and comparative genomic hybridization analysis indicates predominant rearrangements of early replicating chromosome regions in neuroblastoma. Cancer Genet Cytogenet 141: 32-42.
    • (2003) Cancer Genet Cytogenet , vol.141 , pp. 32-42
    • Schleiermacher, G.1    Janoueix-Lerosey, I.2    Combaret, V.3    Derre, J.4    Couturier, J.5    Aurias, A.6
  • 94
    • 39749177356 scopus 로고    scopus 로고
    • Clinical significance of MYCN amplification and ploidy in favorable-stage neuroblastoma: A report from the Children's Oncology Group
    • Schneiderman J, London WB, Brodeur GM, Castleberry RP, Look AT, Cohn SL. (2008). Clinical significance of MYCN amplification and ploidy in favorable-stage neuroblastoma: a report from the Children's Oncology Group. J Clin Oncol 26: 913-918.
    • (2008) J Clin Oncol , vol.26 , pp. 913-918
    • Schneiderman, J.1    London, W.B.2    Brodeur, G.M.3    Castleberry, R.P.4    Look, A.T.5    Cohn, S.L.6
  • 95
    • 28344437416 scopus 로고    scopus 로고
    • Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling
    • Schramm A, Schulte JH, Klein-Hitpass L, Havers W, Sieverts H, Berwanger B, et al. (2005). Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling. Oncogene 24: 7902-7912.
    • (2005) Oncogene , vol.24 , pp. 7902-7912
    • Schramm, A.1    Schulte, J.H.2    Klein-Hitpass, L.3    Havers, W.4    Sieverts, H.5    Berwanger, B.6
  • 97
    • 0022388606 scopus 로고
    • Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
    • Seeger RC, Brodeur GM, Sather H, Dalton A, Siegel SE, Wong KY, et al. (1985). Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 313: 1111-1116.
    • (1985) N Engl J Med , vol.313 , pp. 1111-1116
    • Seeger, R.C.1    Brodeur, G.M.2    Sather, H.3    Dalton, A.4    Siegel, S.E.5    Wong, K.Y.6
  • 98
    • 0033565765 scopus 로고    scopus 로고
    • The International Neuroblastoma Pathology Classification (the Shimada system)
    • Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B, et al. (1999). The International Neuroblastoma Pathology Classification (the Shimada system). Cancer 86: 364-372.
    • (1999) Cancer , vol.86 , pp. 364-372
    • Shimada, H.1    Ambros, I.M.2    Dehner, L.P.3    Hata, J.4    Joshi, V.V.5    Roald, B.6
  • 100
    • 34547638047 scopus 로고    scopus 로고
    • Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
    • Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, Ishikawa S, et al. (2007). Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 448: 561-566.
    • (2007) Nature , vol.448 , pp. 561-566
    • Soda, M.1    Choi, Y.L.2    Enomoto, M.3    Takada, S.4    Yamashita, Y.5    Ishikawa, S.6
  • 102
    • 33751092280 scopus 로고    scopus 로고
    • Oligonucleotide array-based comparative genomic hybridization (aCGH) of 90 neuroblastomas reveals aberration patterns closely associated with relapse pattern and outcome
    • Spitz R, Oberthuer A, Zapatka M, Brors B, Hero B, Ernestus K, et al. (2006). Oligonucleotide array-based comparative genomic hybridization (aCGH) of 90 neuroblastomas reveals aberration patterns closely associated with relapse pattern and outcome. Genes Chromosomes Cancer 45: 1130-1142.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 1130-1142
    • Spitz, R.1    Oberthuer, A.2    Zapatka, M.3    Brors, B.4    Hero, B.5    Ernestus, K.6
  • 103
    • 33645749497 scopus 로고    scopus 로고
    • High-resolution analysis of chromosomal breakpoints and genomic instability identifies PTPRD as a candidate tumor suppressor gene in neuroblastoma
    • Stallings RL, Nair P, Maris JM, Catchpoole D, McDermott M, O'Meara A, et al. (2006). High-resolution analysis of chromosomal breakpoints and genomic instability identifies PTPRD as a candidate tumor suppressor gene in neuroblastoma. Cancer Res 66: 3673-3680.
    • (2006) Cancer Res , vol.66 , pp. 3673-3680
    • Stallings, R.L.1    Nair, P.2    Maris, J.M.3    Catchpoole, D.4    McDermott, M.5    O'Meara, A.6
  • 104
    • 0035907231 scopus 로고    scopus 로고
    • Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin
    • Stoica GE, Kuo A, Aigner A, Sunitha I, Souttou B, Malerczyk C, et al. (2001). Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin. J Biol Chem 276: 16772-16779.
    • (2001) J Biol Chem , vol.276 , pp. 16772-16779
    • Stoica, G.E.1    Kuo, A.2    Aigner, A.3    Sunitha, I.4    Souttou, B.5    Malerczyk, C.6
  • 105
    • 0037184128 scopus 로고    scopus 로고
    • Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types
    • Stoica GE, Kuo A, Powers C, Bowden ET, Sale EB, Riegel AT, et al. (2002). Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types. J Biol Chem 277: 35990-35998.
    • (2002) J Biol Chem , vol.277 , pp. 35990-35998
    • Stoica, G.E.1    Kuo, A.2    Powers, C.3    Bowden, E.T.4    Sale, E.B.5    Riegel, A.T.6
  • 106
    • 5144225768 scopus 로고    scopus 로고
    • Positional gene expression analysis identifies 12q overexpression and amplification in a subset of neuroblastomas
    • Su WT, Alaminos M, Mora J, Cheung NK, La Quaglia MP, Gerald WL. (2004). Positional gene expression analysis identifies 12q overexpression and amplification in a subset of neuroblastomas. Cancer Genet Cytogenet 154: 131-137.
    • (2004) Cancer Genet Cytogenet , vol.154 , pp. 131-137
    • Su, W.T.1    Alaminos, M.2    Mora, J.3    Cheung, N.K.4    La Quaglia, M.P.5    Gerald, W.L.6
  • 107
    • 38349064796 scopus 로고    scopus 로고
    • Novel risk stratification of patients with neuroblastoma by genomic signature, which is independent of molecular signature
    • Tomioka N, Oba S, Ohira M, Misra A, Fridlyand J, Ishii S, et al. (2008). Novel risk stratification of patients with neuroblastoma by genomic signature, which is independent of molecular signature. Oncogene 27: 441-449.
    • (2008) Oncogene , vol.27 , pp. 441-449
    • Tomioka, N.1    Oba, S.2    Ohira, M.3    Misra, A.4    Fridlyand, J.5    Ishii, S.6
  • 109
    • 28744432065 scopus 로고    scopus 로고
    • Molecular consequences of PHOX2B missense, frameshift and alanine expansion mutations leading to autonomic dysfunction
    • Trochet D, Hong SJ, Lim JK, Brunet JF, Munnich A, Kim KS, et al. (2005a). Molecular consequences of PHOX2B missense, frameshift and alanine expansion mutations leading to autonomic dysfunction. Hum Mol Genet 14: 3697-3708.
    • (2005) Hum Mol Genet , vol.14 , pp. 3697-3708
    • Trochet, D.1    Hong, S.J.2    Lim, J.K.3    Brunet, J.F.4    Munnich, A.5    Kim, K.S.6
  • 110
    • 64049114154 scopus 로고    scopus 로고
    • In vitro studies of non poly alanine PHOX2B mutations argue against a loss-of-function mechanism for congenital central hypoventilation
    • Trochet D, Mathieu Y, Pontual L, Savarirayan R, Munnich A, Brunet JF, et al. (2009). in vitro studies of non poly alanine PHOX2B mutations argue against a loss-of-function mechanism for congenital central hypoventilation. Hum Mutat 30: E421-E431.
    • (2009) Hum Mutat , vol.30
    • Trochet, D.1    Mathieu, Y.2    Pontual, L.3    Savarirayan, R.4    Munnich, A.5    Brunet, J.F.6
  • 111
    • 13844253252 scopus 로고    scopus 로고
    • PHOX2B genotype allows for prediction of tumor risk in Congenital Central Hypoventilation Syndrome
    • Trochet D, O'Brien LM, Gozal D, Trang H, Nordenskjold A, Laudier B, et al. (2005b). PHOX2B genotype allows for prediction of tumor risk in Congenital Central Hypoventilation Syndrome. Am J Hum Genet 76: 421-426.
    • (2005) Am J Hum Genet , vol.76 , pp. 421-426
    • Trochet, D.1    O'Brien, L.M.2    Gozal, D.3    Trang, H.4    Nordenskjold, A.5    Laudier, B.6
  • 112
    • 0344441893 scopus 로고    scopus 로고
    • Vav-promoter regulated oncogenic fusion protein NPM-ALK in transgenic mice causes B-cell lymphomas with hyperactive Jun kinase
    • Turner SD, Tooze R, Maclennan K, Alexander DR. (2003). Vav-promoter regulated oncogenic fusion protein NPM-ALK in transgenic mice causes B-cell lymphomas with hyperactive Jun kinase. Oncogene 22: 7750-7761.
    • (2003) Oncogene , vol.22 , pp. 7750-7761
    • Turner, S.D.1    Tooze, R.2    MacLennan, K.3    Alexander, D.R.4
  • 113
    • 20944433656 scopus 로고    scopus 로고
    • MYCN haploinsufficiency is associated with reduced brain size and intestinal atresias in Feingold syndrome
    • van Bokhoven H, Celli J, van Reeuwijk J, Rinne T, Glaudemans B, van Beusekom E, et al. (2005). MYCN haploinsufficiency is associated with reduced brain size and intestinal atresias in Feingold syndrome. Nat Genet 37: 465-467.
    • (2005) Nat Genet , vol.37 , pp. 465-467
    • Van Bokhoven, H.1    Celli, J.2    Van Reeuwijk, J.3    Rinne, T.4    Glaudemans, B.5    Van Beusekom, E.6
  • 115
    • 0034849513 scopus 로고    scopus 로고
    • Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in neuro-blastoma cell lines
    • Van Roy N, Van Limbergen H, Vandesompele J, Van Gele M, Poppe B, Salwen H, et al. (2001). Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in neuro-blastoma cell lines. Genes Chromosomes Cancer 32: 126-135.
    • (2001) Genes Chromosomes Cancer , vol.32 , pp. 126-135
    • Van Roy, N.1    Van Limbergen, H.2    Vandesompele, J.3    Van Gele, M.4    Poppe, B.5    Salwen, H.6
  • 116
    • 31944434940 scopus 로고    scopus 로고
    • Translocation-excision-deletion-amplifica-tion mechanism leading to nonsyntenic coamplification of MYC and ATBF1
    • Van Roy N, Vandesompele J, Menten B, Nilsson H, De Smet E, Rocchi M, et al. (2006). Translocation-excision-deletion-amplifica-tion mechanism leading to nonsyntenic coamplification of MYC and ATBF1. Genes Chromosomes Cancer 45: 107-117.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 107-117
    • Van Roy, N.1    Vandesompele, J.2    Menten, B.3    Nilsson, H.4    De Smet, E.5    Rocchi, M.6
  • 117
    • 48249093445 scopus 로고    scopus 로고
    • A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes
    • Vandepoele K, Andries V, Van Roy N, Staes K, Vandesompele J, Laureys G, et al. (2008). A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes. PLoS One 3: e2207.
    • (2008) PLoS One , vol.3
    • Vandepoele, K.1    Andries, V.2    Van Roy, N.3    Staes, K.4    Vandesompele, J.5    Laureys, G.6
  • 118
    • 26444529054 scopus 로고    scopus 로고
    • A novel gene family NBPF: Intricate structure generated by gene duplications during primate evolution
    • Vandepoele K, Van Roy N, Staes K, Speleman F, van Roy F. (2005). A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution. Mol Biol Evol 22: 2265-2274.
    • (2005) Mol Biol Evol , vol.22 , pp. 2265-2274
    • Vandepoele, K.1    Van Roy, N.2    Staes, K.3    Speleman, F.4    Van Roy, F.5
  • 119
    • 20244370742 scopus 로고    scopus 로고
    • Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma
    • Vandesompele J, Baudis M, De Preter K, Van Roy N, Ambros P, Bown N, et al. (2005). Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma. J Clin Oncol 23: 2280-2299.
    • (2005) J Clin Oncol , vol.23 , pp. 2280-2299
    • Vandesompele, J.1    Baudis, M.2    De Preter, K.3    Van Roy, N.4    Ambros, P.5    Bown, N.6
  • 120
    • 67649372693 scopus 로고    scopus 로고
    • Predicting outcomes for children with neuroblastoma using a multigene-expression signature: A retrospective SIOPEN/COG/GPOH study
    • Vermeulen J, De Preter K, Naranjo A, Vercruysse L, Van Roy N, Hellemans J, et al. (2009). Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study. Lancet Oncol 10: 663-671.
    • (2009) Lancet Oncol , vol.10 , pp. 663-671
    • Vermeulen, J.1    De Preter, K.2    Naranjo, A.3    Vercruysse, L.4    Van Roy, N.5    Hellemans, J.6
  • 121
    • 33748192942 scopus 로고    scopus 로고
    • The Myc oncoprotein as a therapeutic target for human cancer
    • Vita M, Henriksson M. (2006). The Myc oncoprotein as a therapeutic target for human cancer. Semin Cancer Biol 16: 318-330.
    • (2006) Semin Cancer Biol , vol.16 , pp. 318-330
    • Vita, M.1    Henriksson, M.2
  • 122
    • 33745700217 scopus 로고    scopus 로고
    • Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number
    • Wang Q, Diskin S, Rappaport E, Attiyeh E, Mosse Y, Shue D, et al. (2006). Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. Cancer Res 66: 6050-6062.
    • (2006) Cancer Res , vol.66 , pp. 6050-6062
    • Wang, Q.1    Diskin, S.2    Rappaport, E.3    Attiyeh, E.4    Mosse, Y.5    Shue, D.6
  • 123
    • 65749083100 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase: Role in cancer pathogenesis and small-molecule inhibitor development for therapy
    • Webb TR, Slavish J, George RE, Look AT, Xue L, Jiang Q, et al. (2009). Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy. Expert Rev Anticancer Ther 9: 331-356.
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 331-356
    • Webb, T.R.1    Slavish, J.2    George, R.E.3    Look, A.T.4    Xue, L.5    Jiang, Q.6
  • 125
    • 0037025173 scopus 로고    scopus 로고
    • Cancer. Addiction to oncogenes-the Achilles heal of cancer
    • Weinstein IB. (2002). Cancer. Addiction to oncogenes-the Achilles heal of cancer. Science 297: 63-64.
    • (2002) Science , vol.297 , pp. 63-64
    • Weinstein, I.B.1
  • 126
    • 44849093562 scopus 로고    scopus 로고
    • Oncogene addiction
    • discussion 3080
    • Weinstein IB, Joe A. (2008). Oncogene addiction. Cancer Res 68: 3077-3080; discussion 3080.
    • (2008) Cancer Res , vol.68 , pp. 3077-3080
    • Weinstein, I.B.1    Joe, A.2
  • 127
    • 0030999641 scopus 로고    scopus 로고
    • Targeted expression of MYCN causes neuroblastoma in transgenic mice
    • Weiss WA, Aldape K, Mohapatra G, Feuerstein BG, Bishop JM. (1997). Targeted expression of MYCN causes neuroblastoma in transgenic mice. EMBO J 16: 2985-2995.
    • (1997) EMBO J , vol.16 , pp. 2985-2995
    • Weiss, W.A.1    Aldape, K.2    Mohapatra, G.3    Feuerstein, B.G.4    Bishop, J.M.5
  • 128
    • 34249812122 scopus 로고    scopus 로고
    • MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
    • Welch C, Chen Y, Stallings RL. (2007). MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene 26: 5017-5022.
    • (2007) Oncogene , vol.26 , pp. 5017-5022
    • Welch, C.1    Chen, Y.2    Stallings, R.L.3
  • 129
    • 55649123695 scopus 로고    scopus 로고
    • Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas
    • Westermann F, Muth D, Benner A, Bauer T, Henrich KO, Oberthuer A, et al. (2008). Distinct transcriptional MYCN/cFMYC activities are associated with spontaneous regression or malignant progression in neuroblastomas. Genome Biol 9: R150.
    • (2008) Genome Biol , vol.9
    • Westermann, F.1    Muth, D.2    Benner, A.3    Bauer, T.4    Henrich, K.O.5    Oberthuer, A.6
  • 130
    • 0033531259 scopus 로고    scopus 로고
    • Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma
    • Wimmer K, Zhu XX, Lamb BJ, Kuick R, Ambros PF, Kovar H, et al. (1999). Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma. Oncogene 18: 233-238.
    • (1999) Oncogene , vol.18 , pp. 233-238
    • Wimmer, K.1    Zhu, X.X.2    Lamb, B.J.3    Kuick, R.4    Ambros, P.F.5    Kovar, H.6
  • 131
    • 0036498755 scopus 로고    scopus 로고
    • Marginal decrease in mortality and marked increase in incidence as a result of neuroblastoma screening at 6 months of age: Cohort study in seven prefectures in Japan
    • Yamamoto K, Ohta S, Ito E, Hayashi Y, Asami T, Mabuchi O, et al. (2002). Marginal decrease in mortality and marked increase in incidence as a result of neuroblastoma screening at 6 months of age: cohort study in seven prefectures in Japan. J Clin Oncol 20: 1209-1214.
    • (2002) J Clin Oncol , vol.20 , pp. 1209-1214
    • Yamamoto, K.1    Ohta, S.2    Ito, E.3    Hayashi, Y.4    Asami, T.5    Mabuchi, O.6
  • 132
    • 34249324494 scopus 로고    scopus 로고
    • An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through anti-proliferative and antiangiogenic mechanisms
    • Zou HY, Li Q, Lee JH, Arango ME, McDonnell SR, Yamazaki S, et al. (2007). An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through anti-proliferative and antiangiogenic mechanisms. Cancer Res 67: 4408-4417.
    • (2007) Cancer Res , vol.67 , pp. 4408-4417
    • Zou, H.Y.1    Li, Q.2    Lee, J.H.3    Arango, M.E.4    McDonnell, S.R.5    Yamazaki, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.