Effects of the I559P gp41 change on the conformation and function of the human immunodeficiency virus (HIV-1) membrane envelope glycoprotein trimer

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Alsahafi, Nirmin ^a,b   Debbeche, Olfa ^b,c   Sodroski, Joseph ^d,e,f   Finzi, Andrés ^a,b,c  

^a MCGILL UNIVERSITY   (Canada)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; VIRUS ENVELOPE PROTEIN; DISULFIDE; NEUTRALIZING ANTIBODY; PROTEIN BINDING;

AMINO ACID SUBSTITUTION; ANTIBODY COMBINING SITE; ANTIGEN EXPRESSION; ARTICLE; CELL FUSION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISULFIDE BOND; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN QUATERNARY STRUCTURE; PROTEIN STABILITY; VIRUS ENTRY; VIRUS NEUTRALIZATION; CHEMISTRY; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; METABOLISM; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIBODIES, NEUTRALIZING; ANTIGENS, CD4; DISULFIDES; HEK293 CELLS; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; VIRUS INTERNALIZATION;

EID: 84929483871     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0122111     Document Type: Article

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