Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions

Molecular Cell

Volumn 37, Issue 5, 2010, Pages 656-667

  Finzi, Andrés ^a   Xiang, Shi Hua ^a   Pacheco, Beatriz ^a   Wang, Liping ^a   Haight, Jessica ^a   Kassa, Aemro ^a   Danek, Brenda ^a   Pancera, Marie ^b   Kwong, Peter D ^b   Sodroski, Joseph ^a,c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

HUMDISEASE; PROTEINS; SIGNALING

Indexed keywords

CD4 ANTIGEN; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 41; PROTEIN SUBUNIT; VIRUS ENVELOPE PROTEIN;

ANTIGEN BINDING; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PHENOTYPE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN STRUCTURE; VIRUS ENTRY;

ANIMALS; ANTIGENS, CD4; DOGS; GENOTYPE; HELA CELLS; HIV ENVELOPE PROTEIN GP120; HIV ENVELOPE PROTEIN GP41; HIV PROTEASE; HIV-1; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTATION; PHENOTYPE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CCR5; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; VIRUS INTERNALIZATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77749329921     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2010.02.012     Document Type: Article

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