메뉴 건너뛰기




Volumn 1852, Issue 8, 2015, Pages 1665-1675

Alzheimer's disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers

Author keywords

Alzheimer's disease; Autophagy; Mitochondrial function and biogenesis; Synaptic integrity; Type 2 diabetes

Indexed keywords

ADENINE NUCLEOTIDE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MITOCHONDRIAL PROTEIN; NUCLEAR RESPIRATORY FACTOR 1; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; POSTSYNAPTIC DENSITY PROTEIN 95; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SYNAPTOPHYSIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; TRANSCRIPTION FACTOR NRF2; BIOLOGICAL MARKER;

EID: 84929430489     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2015.05.001     Document Type: Article
Times cited : (126)

References (79)
  • 1
    • 84897109680 scopus 로고    scopus 로고
    • Alzheimer's disease and type 2 diabetes: multiple mechanisms contribute to interactions
    • Jayaraman A., Pike C.J. Alzheimer's disease and type 2 diabetes: multiple mechanisms contribute to interactions. Curr. Diab. Rep. 2014, 14:476.
    • (2014) Curr. Diab. Rep. , vol.14 , pp. 476
    • Jayaraman, A.1    Pike, C.J.2
  • 2
    • 84870213683 scopus 로고    scopus 로고
    • Altered APP processing in insulin-resistant conditions is mediated by autophagosome accumulation via the inhibition of mammalian target of rapamycin pathway
    • Son S.M., Song H., Byun J., Park K.S., Jang H.C., Park Y.J., Mook-Jung I. Altered APP processing in insulin-resistant conditions is mediated by autophagosome accumulation via the inhibition of mammalian target of rapamycin pathway. Diabetes 2012, 61(12):3126-3138.
    • (2012) Diabetes , vol.61 , Issue.12 , pp. 3126-3138
    • Son, S.M.1    Song, H.2    Byun, J.3    Park, K.S.4    Jang, H.C.5    Park, Y.J.6    Mook-Jung, I.7
  • 3
    • 55749114205 scopus 로고    scopus 로고
    • Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury
    • Yin W., Signore A.P., Iwai M., Cao G., Gao Y., Chen J. Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury. Stroke 2008, 39:3057-3063.
    • (2008) Stroke , vol.39 , pp. 3057-3063
    • Yin, W.1    Signore, A.P.2    Iwai, M.3    Cao, G.4    Gao, Y.5    Chen, J.6
  • 4
    • 0033782296 scopus 로고    scopus 로고
    • Mitochondrial participation in ischemic and traumatic neural cell death
    • Fiskum G. Mitochondrial participation in ischemic and traumatic neural cell death. J. Neurotrauma 2000, 17:843-855.
    • (2000) J. Neurotrauma , vol.17 , pp. 843-855
    • Fiskum, G.1
  • 6
    • 84925858717 scopus 로고    scopus 로고
    • Mitochondrial biogenesis: a therapeutic target for neurodevelopmental disorders and neurodegenerative diseases
    • Uittenbogaard M., Chiaramello A. Mitochondrial biogenesis: a therapeutic target for neurodevelopmental disorders and neurodegenerative diseases. Curr. Pharm. Des. 2014, 20(35):5574-5593.
    • (2014) Curr. Pharm. Des. , vol.20 , Issue.35 , pp. 5574-5593
    • Uittenbogaard, M.1    Chiaramello, A.2
  • 7
    • 0025339440 scopus 로고
    • Treatment of cervical intraepithelial neoplasia: experience with the low-voltage diathermy loop
    • Whiteley P.F., Olah K.S. Treatment of cervical intraepithelial neoplasia: experience with the low-voltage diathermy loop. Am. J. Obstet. Gynecol. 1990, 162:1272-1277.
    • (1990) Am. J. Obstet. Gynecol. , vol.162 , pp. 1272-1277
    • Whiteley, P.F.1    Olah, K.S.2
  • 10
    • 58049218922 scopus 로고    scopus 로고
    • Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
    • Wang X., Su B., Siedlak S.L., Moreira P.I., Fujioka H., Wang Y., Casadesus G., Zhu X. Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:19318-19323.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 19318-19323
    • Wang, X.1    Su, B.2    Siedlak, S.L.3    Moreira, P.I.4    Fujioka, H.5    Wang, Y.6    Casadesus, G.7    Zhu, X.8
  • 11
    • 84863091207 scopus 로고    scopus 로고
    • Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression
    • Heyward F.D., Walton R.G., Carle M.S., Coleman M.A., Garvey W.T., Sweatt J.D. Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression. Neurobiol. Learn. Mem. 2012, 98:25-32.
    • (2012) Neurobiol. Learn. Mem. , vol.98 , pp. 25-32
    • Heyward, F.D.1    Walton, R.G.2    Carle, M.S.3    Coleman, M.A.4    Garvey, W.T.5    Sweatt, J.D.6
  • 12
    • 84880926594 scopus 로고    scopus 로고
    • Effects of resveratrol and SIRT1 on PGC-1alpha activity and mitochondrial biogenesis: a reevaluation
    • Higashida K., Kim S.H., Jung S.R., Asaka M., Holloszy J.O., Han D.H. Effects of resveratrol and SIRT1 on PGC-1alpha activity and mitochondrial biogenesis: a reevaluation. PLoS Biol. 2013, 11:e1001603.
    • (2013) PLoS Biol. , vol.11 , pp. e1001603
    • Higashida, K.1    Kim, S.H.2    Jung, S.R.3    Asaka, M.4    Holloszy, J.O.5    Han, D.H.6
  • 14
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N., Levine B., Cuervo A.M., Klionsky D.J. Autophagy fights disease through cellular self-digestion. Nature 2008, 451:1069-1075.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 17
    • 4344689871 scopus 로고    scopus 로고
    • Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease
    • Yu W.H., Kumar A., Peterhoff C., Shapiro Kulnane L., Uchiyama Y., Lamb B.T., Cuervo A.M., Nixon R.A. Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease. Int. J. Biochem. Cell Biol. 2004, 36:2531-2540.
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 2531-2540
    • Yu, W.H.1    Kumar, A.2    Peterhoff, C.3    Shapiro Kulnane, L.4    Uchiyama, Y.5    Lamb, B.T.6    Cuervo, A.M.7    Nixon, R.A.8
  • 18
    • 84871417031 scopus 로고    scopus 로고
    • Role of mitochondrial homeostasis and dynamics in Alzheimer's disease
    • Selfridge J.E., L.E, Lu J., Swerdlow R.H. Role of mitochondrial homeostasis and dynamics in Alzheimer's disease. Neurobiol. Dis. 2013, 51:3-12.
    • (2013) Neurobiol. Dis. , vol.51 , pp. 3-12
    • Selfridge, J.E.1    Lu, J.2    Swerdlow, R.H.3
  • 21
    • 34047179973 scopus 로고    scopus 로고
    • Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy
    • Kaniuk N.A., Kiraly M., Bates H., Vranic M., Volchuk A., Brumell J.H. Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy. Diabetes 2007, 56:930-939.
    • (2007) Diabetes , vol.56 , pp. 930-939
    • Kaniuk, N.A.1    Kiraly, M.2    Bates, H.3    Vranic, M.4    Volchuk, A.5    Brumell, J.H.6
  • 22
    • 84870895663 scopus 로고    scopus 로고
    • Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions
    • Son S.M., Song H., Byun J., Park K.S., Jang H.C., Park Y.J., Mook-Jung I. Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions. Autophagy 2012, 8:1842-1844.
    • (2012) Autophagy , vol.8 , pp. 1842-1844
    • Son, S.M.1    Song, H.2    Byun, J.3    Park, K.S.4    Jang, H.C.5    Park, Y.J.6    Mook-Jung, I.7
  • 23
    • 79955973768 scopus 로고    scopus 로고
    • 3-n-butylphthalide (NBP) attenuated neuronal autophagy and amyloid-beta expression in diabetic mice subjected to brain ischemia
    • Zhang T., Yan W., Li Q., Fu J., Liu K., Jia W., Sun X., Liu X. 3-n-butylphthalide (NBP) attenuated neuronal autophagy and amyloid-beta expression in diabetic mice subjected to brain ischemia. Neurol. Res. 2011, 33:396-404.
    • (2011) Neurol. Res. , vol.33 , pp. 396-404
    • Zhang, T.1    Yan, W.2    Li, Q.3    Fu, J.4    Liu, K.5    Jia, W.6    Sun, X.7    Liu, X.8
  • 24
    • 84860599622 scopus 로고    scopus 로고
    • Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities
    • Carvalho C., Cardoso S., Correia S.C., Santos R.X., Santos M.S., Baldeiras I., Oliveira C.R., Moreira P.I. Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities. Diabetes 2012, 61:1234-1242.
    • (2012) Diabetes , vol.61 , pp. 1234-1242
    • Carvalho, C.1    Cardoso, S.2    Correia, S.C.3    Santos, R.X.4    Santos, M.S.5    Baldeiras, I.6    Oliveira, C.R.7    Moreira, P.I.8
  • 26
    • 29744466425 scopus 로고
    • Determination of serum proteins by means of the biuret reaction
    • Gornall A.G., Bardawill C.J., David M.M. Determination of serum proteins by means of the biuret reaction. J. Biol. Chem. 1949, 177:751-766.
    • (1949) J. Biol. Chem. , vol.177 , pp. 751-766
    • Gornall, A.G.1    Bardawill, C.J.2    David, M.M.3
  • 27
    • 77957003282 scopus 로고
    • [7] Mitochondrial respiratory control and the polarographic measurement of ADP:O ratios
    • Academic Press, M.E.P. Ronald, W. Estabrook (Eds.)
    • Estabrook R.W. [7] Mitochondrial respiratory control and the polarographic measurement of ADP:O ratios. Methods in Enzymology 1967, vol. 10:41-47. Academic Press. M.E.P. Ronald, W. Estabrook (Eds.).
    • (1967) Methods in Enzymology , vol.10 , pp. 41-47
    • Estabrook, R.W.1
  • 28
    • 0018665167 scopus 로고
    • Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state
    • Kamo N., Muratsugu M., Hongoh R., Kobatake Y. Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state. J. Membr. Biol. 1979, 49:105-121.
    • (1979) J. Membr. Biol. , vol.49 , pp. 105-121
    • Kamo, N.1    Muratsugu, M.2    Hongoh, R.3    Kobatake, Y.4
  • 29
    • 0002461479 scopus 로고
    • The use of tetraphenylphosphonium (TPP+) to measure membrane potentials in mitochondria: membrane binding and respiratory effects
    • Jensen B., Gunther T. The use of tetraphenylphosphonium (TPP+) to measure membrane potentials in mitochondria: membrane binding and respiratory effects. Biophys. J. 1984, 49:105-121.
    • (1984) Biophys. J. , vol.49 , pp. 105-121
    • Jensen, B.1    Gunther, T.2
  • 30
    • 0017339912 scopus 로고
    • Selective electrode for dibenzyl dimethyl ammonium cation as indicator of the membrane potential in biological systems
    • Muratsugu M., Kamo N., Kurihara K., Kobatake Y. Selective electrode for dibenzyl dimethyl ammonium cation as indicator of the membrane potential in biological systems. Biochim. Biophys. Acta 1977, 464:613-619.
    • (1977) Biochim. Biophys. Acta , vol.464 , pp. 613-619
    • Muratsugu, M.1    Kamo, N.2    Kurihara, K.3    Kobatake, Y.4
  • 32
    • 33749041268 scopus 로고    scopus 로고
    • Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagy
    • Eskelinen E.L. Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagy. Mol. Aspects Med. 2006, 27:495-502.
    • (2006) Mol. Aspects Med. , vol.27 , pp. 495-502
    • Eskelinen, E.L.1
  • 33
    • 0031670604 scopus 로고    scopus 로고
    • The association of weight change in Alzheimer's disease with severity of disease and mortality: a longitudinal analysis
    • White H., Pieper C., Schmader K. The association of weight change in Alzheimer's disease with severity of disease and mortality: a longitudinal analysis. J. Am. Geriatr. Soc. 1998, 46:1223-1227.
    • (1998) J. Am. Geriatr. Soc. , vol.46 , pp. 1223-1227
    • White, H.1    Pieper, C.2    Schmader, K.3
  • 34
    • 0035128130 scopus 로고    scopus 로고
    • Circulating leptin levels and weight loss in Alzheimer's disease patients
    • Power D.A., Noel J., Collins R., O'Neill D. Circulating leptin levels and weight loss in Alzheimer's disease patients. Dement. Geriatr. Cogn. Disord. 2001, 12:167-170.
    • (2001) Dement. Geriatr. Cogn. Disord. , vol.12 , pp. 167-170
    • Power, D.A.1    Noel, J.2    Collins, R.3    O'Neill, D.4
  • 35
    • 33947581042 scopus 로고    scopus 로고
    • Systemic and brain metabolic dysfunction as a new paradigm for approaching Alzheimer's dementia
    • Giordano V., Peluso G., Iannuccelli M., Benatti P., Nicolai R., Calvani M. Systemic and brain metabolic dysfunction as a new paradigm for approaching Alzheimer's dementia. Neurochem. Res. 2007, 32:555-567.
    • (2007) Neurochem. Res. , vol.32 , pp. 555-567
    • Giordano, V.1    Peluso, G.2    Iannuccelli, M.3    Benatti, P.4    Nicolai, R.5    Calvani, M.6
  • 36
    • 84897146296 scopus 로고    scopus 로고
    • Selective inhibition of PI3K/Akt/mTOR signaling pathway regulates autophagy of macrophage and vulnerability of atherosclerotic plaque
    • Zhai C., Cheng J., Mujahid H., Wang H., Kong J., Yin Y., Li J., Zhang Y., Ji X., Chen W. Selective inhibition of PI3K/Akt/mTOR signaling pathway regulates autophagy of macrophage and vulnerability of atherosclerotic plaque. PLoS ONE 2014, 9:e90563.
    • (2014) PLoS ONE , vol.9 , pp. e90563
    • Zhai, C.1    Cheng, J.2    Mujahid, H.3    Wang, H.4    Kong, J.5    Yin, Y.6    Li, J.7    Zhang, Y.8    Ji, X.9    Chen, W.10
  • 37
    • 21344459656 scopus 로고    scopus 로고
    • MTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease
    • Lafay-Chebassier C., Paccalin M., Page G., Barc-Pain S., Perault-Pochat M.C., Gil R., Pradier L., Hugon J. mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease. J. Neurochem. 2005, 94:215-225.
    • (2005) J. Neurochem. , vol.94 , pp. 215-225
    • Lafay-Chebassier, C.1    Paccalin, M.2    Page, G.3    Barc-Pain, S.4    Perault-Pochat, M.C.5    Gil, R.6    Pradier, L.7    Hugon, J.8
  • 38
    • 77951227122 scopus 로고    scopus 로고
    • Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments
    • Caccamo A., Majumder S., Richardson A., Strong R., Oddo S. Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments. J. Biol. Chem. 2010, 285:13107-13120.
    • (2010) J. Biol. Chem. , vol.285 , pp. 13107-13120
    • Caccamo, A.1    Majumder, S.2    Richardson, A.3    Strong, R.4    Oddo, S.5
  • 39
  • 40
    • 65649154065 scopus 로고    scopus 로고
    • Lean and obese Zucker rats exhibit different patterns of p70s6 kinase regulation in the tibialis anterior muscle in response to high-force muscle contraction
    • Katta A., Karkala S.K., Wu M., Meduru S., Desai D.H., Rice K.M., Blough E.R. Lean and obese Zucker rats exhibit different patterns of p70s6 kinase regulation in the tibialis anterior muscle in response to high-force muscle contraction. Muscle Nerve 2009, 39:503-511.
    • (2009) Muscle Nerve , vol.39 , pp. 503-511
    • Katta, A.1    Karkala, S.K.2    Wu, M.3    Meduru, S.4    Desai, D.H.5    Rice, K.M.6    Blough, E.R.7
  • 41
    • 84894143655 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein expression
    • Das A., Durrant D., Koka S., Salloum F.N., Xi L., Kukreja R.C. Mammalian target of rapamycin (mTOR) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein expression. J. Biol. Chem. 2014, 289:4145-4160.
    • (2014) J. Biol. Chem. , vol.289 , pp. 4145-4160
    • Das, A.1    Durrant, D.2    Koka, S.3    Salloum, F.N.4    Xi, L.5    Kukreja, R.C.6
  • 44
    • 84875450015 scopus 로고    scopus 로고
    • Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes
    • He C., Zhu H., Li H., Zou M.H., Xie Z. Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes. Diabetes 2013, 62:1270-1281.
    • (2013) Diabetes , vol.62 , pp. 1270-1281
    • He, C.1    Zhu, H.2    Li, H.3    Zou, M.H.4    Xie, Z.5
  • 45
    • 2642620565 scopus 로고    scopus 로고
    • Bcl-2 and Bax protein expression in Alzheimer's disease
    • Tortosa A., Lopez E., Ferrer I. Bcl-2 and Bax protein expression in Alzheimer's disease. Acta Neuropathol. 1998, 95:407-412.
    • (1998) Acta Neuropathol. , vol.95 , pp. 407-412
    • Tortosa, A.1    Lopez, E.2    Ferrer, I.3
  • 46
    • 79956048660 scopus 로고    scopus 로고
    • Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models
    • Khandelwal P.J., Herman A.M., Hoe H.S., Rebeck G.W., Moussa C.E. Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models. Hum. Mol. Genet. 2011, 20:2091-2102.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 2091-2102
    • Khandelwal, P.J.1    Herman, A.M.2    Hoe, H.S.3    Rebeck, G.W.4    Moussa, C.E.5
  • 47
    • 84881490638 scopus 로고    scopus 로고
    • Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance
    • Lonskaya I., Hebron M.L., Desforges N.M., Franjie A., Moussa C.E. Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance. EMBO Mol. Med. 2013, 5:1247-1262.
    • (2013) EMBO Mol. Med. , vol.5 , pp. 1247-1262
    • Lonskaya, I.1    Hebron, M.L.2    Desforges, N.M.3    Franjie, A.4    Moussa, C.E.5
  • 48
    • 77956400005 scopus 로고    scopus 로고
    • Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance
    • Yang L., Li P., Fu S., Calay E.S., Hotamisligil G.S. Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab. 2010, 11:467-478.
    • (2010) Cell Metab. , vol.11 , pp. 467-478
    • Yang, L.1    Li, P.2    Fu, S.3    Calay, E.S.4    Hotamisligil, G.S.5
  • 49
    • 77956834462 scopus 로고    scopus 로고
    • Autophagy: a potential link between obesity and insulin resistance
    • Codogno P., Meijer A.J. Autophagy: a potential link between obesity and insulin resistance. Cell Metab. 2010, 11:449-451.
    • (2010) Cell Metab. , vol.11 , pp. 449-451
    • Codogno, P.1    Meijer, A.J.2
  • 52
    • 33749074277 scopus 로고    scopus 로고
    • Neuronal macroautophagy: from development to degeneration
    • Boland B., Nixon R.A. Neuronal macroautophagy: from development to degeneration. Mol. Aspects Med. 2006, 27:503-519.
    • (2006) Mol. Aspects Med. , vol.27 , pp. 503-519
    • Boland, B.1    Nixon, R.A.2
  • 55
    • 0028046233 scopus 로고
    • Regulation of glycosylation of Lamp-1 in the bovine renal epithelial cell line NBL-1 by changes in the concentration of extracellular phosphate
    • Helps C.R., McGivan J.D. Regulation of glycosylation of Lamp-1 in the bovine renal epithelial cell line NBL-1 by changes in the concentration of extracellular phosphate. Biochem. J. 1994, 303(Pt 2):613-618.
    • (1994) Biochem. J. , vol.303 , pp. 613-618
    • Helps, C.R.1    McGivan, J.D.2
  • 58
    • 79955969705 scopus 로고    scopus 로고
    • Autophagy failure in Alzheimer's disease-locating the primary defect
    • Nixon R.A., Yang D.S. Autophagy failure in Alzheimer's disease-locating the primary defect. Neurobiol. Dis. 2011, 43:38-45.
    • (2011) Neurobiol. Dis. , vol.43 , pp. 38-45
    • Nixon, R.A.1    Yang, D.S.2
  • 61
    • 42049114034 scopus 로고    scopus 로고
    • Transcriptional paradigms in mammalian mitochondrial biogenesis and function
    • Scarpulla R.C. Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol. Rev. 2008, 88:611-638.
    • (2008) Physiol. Rev. , vol.88 , pp. 611-638
    • Scarpulla, R.C.1
  • 62
    • 58849149820 scopus 로고    scopus 로고
    • Coupling of energy metabolism and synaptic transmission at the transcriptional level: role of nuclear respiratory factor 1 in regulating both cytochrome c oxidase and NMDA glutamate receptor subunit genes
    • Dhar S.S., Wong-Riley M.T. Coupling of energy metabolism and synaptic transmission at the transcriptional level: role of nuclear respiratory factor 1 in regulating both cytochrome c oxidase and NMDA glutamate receptor subunit genes. J. Neurosci. 2009, 29:483-492.
    • (2009) J. Neurosci. , vol.29 , pp. 483-492
    • Dhar, S.S.1    Wong-Riley, M.T.2
  • 63
    • 69949105097 scopus 로고    scopus 로고
    • Transcriptional coupling of synaptic transmission and energy metabolism: role of nuclear respiratory factor 1 in co-regulating neuronal nitric oxide synthase and cytochrome c oxidase genes in neurons
    • Dhar S.S., Liang H.L., Wong-Riley M.T. Transcriptional coupling of synaptic transmission and energy metabolism: role of nuclear respiratory factor 1 in co-regulating neuronal nitric oxide synthase and cytochrome c oxidase genes in neurons. Biochim. Biophys. Acta 2009, 1793:1604-1613.
    • (2009) Biochim. Biophys. Acta , vol.1793 , pp. 1604-1613
    • Dhar, S.S.1    Liang, H.L.2    Wong-Riley, M.T.3
  • 64
    • 48449104125 scopus 로고    scopus 로고
    • A combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of type 2 diabetic Goto-Kakizaki rats
    • Shen W., Hao J., Tian C., Ren J., Yang L., Li X., Luo C., Cotma C.W., Liu J. A combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of type 2 diabetic Goto-Kakizaki rats. PLoS ONE 2008, 3:e2328.
    • (2008) PLoS ONE , vol.3 , pp. e2328
    • Shen, W.1    Hao, J.2    Tian, C.3    Ren, J.4    Yang, L.5    Li, X.6    Luo, C.7    Cotma, C.W.8    Liu, J.9
  • 66
    • 84055204963 scopus 로고    scopus 로고
    • Role of mitochondria biogenesis in the metabolic memory associated with the continued progression of diabetic retinopathy and its regulation by lipoic acid
    • Santos J.M., Kowluru R.A. Role of mitochondria biogenesis in the metabolic memory associated with the continued progression of diabetic retinopathy and its regulation by lipoic acid. Invest. Ophthalmol. Vis. Sci. 2011, 52:8791-8798.
    • (2011) Invest. Ophthalmol. Vis. Sci. , vol.52 , pp. 8791-8798
    • Santos, J.M.1    Kowluru, R.A.2
  • 69
    • 79551575483 scopus 로고    scopus 로고
    • Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo
    • Tan Y., Ichikawa T., Li J., Si Q., Yang H., Chen X., Goldblatt C.S., Meyer C.J., Li X., Cai L., Cui T. Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo. Diabetes 2011, 60:625-633.
    • (2011) Diabetes , vol.60 , pp. 625-633
    • Tan, Y.1    Ichikawa, T.2    Li, J.3    Si, Q.4    Yang, H.5    Chen, X.6    Goldblatt, C.S.7    Meyer, C.J.8    Li, X.9    Cai, L.10    Cui, T.11
  • 70
    • 26444545461 scopus 로고    scopus 로고
    • Is nuclear respiratory factor 2 a master transcriptional coordinator for all ten nuclear-encoded cytochrome c oxidase subunits in neurons?
    • Ongwijitwat S., Wong-Riley M.T. Is nuclear respiratory factor 2 a master transcriptional coordinator for all ten nuclear-encoded cytochrome c oxidase subunits in neurons?. Gene 2005, 360:65-77.
    • (2005) Gene , vol.360 , pp. 65-77
    • Ongwijitwat, S.1    Wong-Riley, M.T.2
  • 71
    • 84875037406 scopus 로고    scopus 로고
    • Impaired transport of mitochondrial transcription factor A (TFAM) and the metabolic memory phenomenon associated with the progression of diabetic retinopathy
    • Santos J.M., Kowluru R.A. Impaired transport of mitochondrial transcription factor A (TFAM) and the metabolic memory phenomenon associated with the progression of diabetic retinopathy. Diabetes Metab. Res. Rev. 2013, 29:204-213.
    • (2013) Diabetes Metab. Res. Rev. , vol.29 , pp. 204-213
    • Santos, J.M.1    Kowluru, R.A.2
  • 72
    • 0035369935 scopus 로고    scopus 로고
    • Peritoneal implantation of macroencapsulated porcine pancreatic islets in diabetic rats ameliorates severe hyperglycemia and prevents retraction and simplification of hippocampal dendrites
    • Magarinos A.M., Jain K., Blount E.D., Reagan L., Smith B.H., McEwen B.S. Peritoneal implantation of macroencapsulated porcine pancreatic islets in diabetic rats ameliorates severe hyperglycemia and prevents retraction and simplification of hippocampal dendrites. Brain Res. 2001, 902:282-287.
    • (2001) Brain Res. , vol.902 , pp. 282-287
    • Magarinos, A.M.1    Jain, K.2    Blount, E.D.3    Reagan, L.4    Smith, B.H.5    McEwen, B.S.6
  • 73
    • 84873733865 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 inhibition prevents learning deficits in diabetic mice
    • King M.R., Anderson N.J., Guernsey L.S., Jolivalt C.G. Glycogen synthase kinase-3 inhibition prevents learning deficits in diabetic mice. J. Neurosci. Res. 2013, 91:506-514.
    • (2013) J. Neurosci. Res. , vol.91 , pp. 506-514
    • King, M.R.1    Anderson, N.J.2    Guernsey, L.S.3    Jolivalt, C.G.4
  • 75
    • 7244223228 scopus 로고    scopus 로고
    • Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence
    • Gylys K.H., Fein J.A., Yang F., Wiley D.J., Miller C.A., Cole G.M. Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence. Am. J. Pathol. 2004, 165:1809-1817.
    • (2004) Am. J. Pathol. , vol.165 , pp. 1809-1817
    • Gylys, K.H.1    Fein, J.A.2    Yang, F.3    Wiley, D.J.4    Miller, C.A.5    Cole, G.M.6
  • 76
    • 33749648798 scopus 로고    scopus 로고
    • Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins
    • Elias G.M., Funke L., Stein V., Grant S.G., Bredt D.S., Nicoll R.A. Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins. Neuron 2006, 52:307-320.
    • (2006) Neuron , vol.52 , pp. 307-320
    • Elias, G.M.1    Funke, L.2    Stein, V.3    Grant, S.G.4    Bredt, D.S.5    Nicoll, R.A.6
  • 77
    • 79958033258 scopus 로고    scopus 로고
    • Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons
    • Kwon S.E., Chapman E.R. Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron 2011, 70:847-854.
    • (2011) Neuron , vol.70 , pp. 847-854
    • Kwon, S.E.1    Chapman, E.R.2
  • 78
    • 0032947530 scopus 로고    scopus 로고
    • Decreased levels of synaptosomal associated protein 25 in the brain of patients with Down syndrome and Alzheimer's disease
    • Greber S., Lubec G., Cairns N., Fountoulakis M. Decreased levels of synaptosomal associated protein 25 in the brain of patients with Down syndrome and Alzheimer's disease. Electrophoresis 1999, 20:928-934.
    • (1999) Electrophoresis , vol.20 , pp. 928-934
    • Greber, S.1    Lubec, G.2    Cairns, N.3    Fountoulakis, M.4
  • 79
    • 77955414626 scopus 로고    scopus 로고
    • Diabetes differentially affects the content of exocytotic proteins in hippocampal and retinal nerve terminals
    • Gaspar J.M., Baptista F.I., Galvao J., Castilho A.F., Cunha R.A., Ambrosio A.F. Diabetes differentially affects the content of exocytotic proteins in hippocampal and retinal nerve terminals. Neuroscience 2010, 169:1589-1600.
    • (2010) Neuroscience , vol.169 , pp. 1589-1600
    • Gaspar, J.M.1    Baptista, F.I.2    Galvao, J.3    Castilho, A.F.4    Cunha, R.A.5    Ambrosio, A.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.