Upregulation of PGC-1α expression by Alzheimer's disease-associated pathway: Presenilin 1/amyloid precursor protein (APP)/intracellular domain of APP

Aging Cell

Volumn 13, Issue 2, 2014, Pages 263-272

  Robinson, Ari ^a,d   Grösgen, Sven ^b   Mett, Janine ^b   Zimmer, Valerie C ^b   Haupenthal, Viola J ^b   Hundsdörfer, Benjamin ^b   Stahlmann, Christoph P ^b   Slobodskoy, Yulia ^a   Müller, Ulrike C ^c   Hartmann, Tobias ^b   Stein, Reuven ^a   Grimm, Marcus O W ^b  

^a TEL AVIV UNIVERSITY   (Israel)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d BAR ILAN UNIVERSITY   (Israel)

Author keywords

Alzheimer's disease; Amyloid precursor protein intracellular domain; Amyloid precursor protein processing; Fe65; Mitochondrial function; PGC1

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMINO ACID; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; MESSENGER RNA; MITOCHONDRIAL PROTEIN; OXYGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMBRYO; ENERGY METABOLISM; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; MOUSE; MUTANT; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; UPREGULATION; WILD TYPE;

MUS;

ALZHEIMER'S DISEASE; AMYLOID PRECURSOR PROTEIN INTRACELLULAR DOMAIN; AMYLOID PRECURSOR PROTEIN PROCESSING; FE65; MITOCHONDRIAL FUNCTION; PGC1-Α;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; HUMANS; MICE; MITOCHONDRIA; PRESENILIN-1; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 84895782808     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12183     Document Type: Article

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