Hirsutenone directly targets PI3K and ERK to inhibit adipogenesis in 3T3-L1 preadipocytes

Journal of Cellular Biochemistry

Volumn 116, Issue 7, 2015, Pages 1361-1370

  Cheong, Lai Yee ^a   Suk, Sujin ^b   Thimmegowda, N R ^c   Chung, Min Yu ^a,d   Yang, Hee ^a   Seo, Sang Gwon ^a   Shwetha, B ^c   Kim, Jong Eun ^a,b   Kwon, Jung Yeon ^e   Kim, Bo Yeon ^c   Lee, Ki Won ^a,b,e  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^d Korea Food Research Institute   (South Korea)

^e Seoul National University   (South Korea)

Author keywords

ADIPOGENESIS; ERK; HIRSUTENONE; MITOTIC CLONAL EXPANSION; PI3K

Indexed keywords

AGENTS AFFECTING LIPID METABOLISM; CCAAT ENHANCER BINDING PROTEIN ALPHA; CYCLIN A1; CYCLIN D1; FATTY ACID SYNTHASE; HIRSUTENONE; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG; CATECHOL DERIVATIVE; HEPTANE DERIVATIVE;

ADIPOGENESIS; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL VIABILITY; CONCENTRATION RESPONSE; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; IMMUNOPRECIPITATION; LIPID STORAGE; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; 3T3 CELL LINE; ANIMAL; CELL CYCLE; CELL SURVIVAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; MOUSE;

ALNUS;

3T3-L1 CELLS; ADIPOGENESIS; ANIMALS; CATECHOLS; CELL CYCLE; CELL SURVIVAL; DIARYLHEPTANOIDS; GENE EXPRESSION REGULATION; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES;

EID: 84929103650     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.25093     Document Type: Article

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