Antioxidative and hepatoprotective diarylheptanoids from the bark of alnus japonica

Planta Medica

Volumn 76, Issue 6, 2010, Pages 626-629

  Tung, Nguyen Huu ^a   Kim, Sang Kyum ^a   Ra, Jeong Chan ^b   Zhao, Yu Zhe ^c   Sohn, Dong Hwan ^c   Kim, Young Ho ^a  

^a Chungnam National University   (South Korea)

^b RNL Bio Co   (South Korea)

^c Wonkwang University   (South Korea)

Author keywords

Alnus japonica; Alusenone; Antioxidative activity; Betulaceae; Diarylheptanoid; Hepatoprotective activity

Indexed keywords

ALNUSIDE A; ALNUSIDE B; ALUSENONE; ANTIOXIDANT; CURCUMIN; HEPTANE DERIVATIVE; HIRSUTANONOL; HIRSUTENONE; OREGONIN; PLATYPHYLLONE; PLATYPHYLLONOL 5 XYLOSE; PLATYPHYLLOSIDE; QUERCETIN; RUBRANOSIDE B; RUBRANOSIDE C; TROLOX C; UNCLASSIFIED DRUG;

ALDER; ALNUS JAPONICA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BARK; CONTROLLED STUDY; DRUG STRUCTURE; LIVER PROTECTION; LIVER TOXICITY; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

ALNUS; ANIMALS; ANTIOXIDANTS; DIARYLHEPTANOIDS; DRUG-INDUCED LIVER INJURY; MOLECULAR STRUCTURE; PLANT BARK; RATS;

ALNUS JAPONICA; BETULACEAE; RATTUS;

EID: 77951030284     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1240595     Document Type: Article

References (23)

1. Lee S J. Korea folk medicine. Seoul Seoul National University Publishing Center Press 1996 40
2. Cho K J. Method of making health drink for reducing hangover using Alnus japonica extract and green tea leaf extract. Korea Patent KR 2006023093. 2006
3. Kim H J., Yeom S H., Kim M K., Shim J G., Paek I N., Lee M W. Nitric oxide and prostaglandin E2 synthesis inhibitory activities of diarylheptanoids from the barks of Alnus japonica Steudel. Arch Pharm Res 2005 28 177-179
4. Kuroyanagi M, Shimomae M, Nagashima Y, Muto N, Okuda T, Kawahara N, Nakane T, Sano T. New diarylheptanoids from Alnus japonica and their antioxidative activity. Chem Pharm Bull 2005 53 1519-1523 (Pubitemid 41744475)
5. Lee M W., Tanaka T, Nonaka G I., Nishioka I. Tannins and related compounds. Part 115. Dimeric ellagitannins from Alnus japonica. Phytochemistry 1992 31 2835-2839
6. Nomura M, Tokoroyama T, Kubota T. Biarylheptanoids and other constituents from wood of Alnus japonica. Phytochemistry 1981 20 1097-1104
7. Wada H, Tachibana H, Fuchino H, Tanaka N. Three new diarylheptanoid glycosides from Alnus japonica. Chem Pharm Bull 1998 46 1054-1055 (Pubitemid 28363339)
8. Gonzalez-Laredo R F., Helm R F., Chen J, Karchesy J J. Two acylated diarylheptanoid glycosides from red alder bark. J Nat Prod 1998 61 1292-1294 (Pubitemid 28513363)
9. Lee M W., Kim N Y., Park M S., Ahn K H., Toh S H., Hahn D R., Kim Y C., Chung H T. Diarylheptanoids with in vitro inducible nitric oxide synthesis inhibitory activity from Alnus hirsuta. Planta Med 2000 66 551-553
10. Lee W S., Kim J R., Im K R., Cho K H., Sok D E., Jeong T S. Antioxidant effects of diarylheptanoid derivatives from Alnus japonica on human LDL oxidation. Planta Med 2005 71 295-299
11. Savikin K, Zdunic G, Stanojkovic T, Juranic Z, Jankovic T, Menkovic N. Preliminary investigation of antiproliferative and antioxidant activity of Alnus incana (L.) Moench and A. viridis (Chaix) DC. Planta Med 2007 73 980-981
12. Joo S S., Choi S E., Kwon J H., Nam S Y., Lee D K., Lee M W. Development of a new anti-atopic agent using the diarylheptanoid from the barks of Alnus japonica and its role in immunological activity. Planta Med 2008 74 77
13. Chen J, Karchesy J J., Gonzalez-Laredo R F. Phenolic diarylheptenones from Alnus rubra bark. Planta Med 1998 64 74-75 (Pubitemid 28060004)
14. Giang P M., Son P T., Matsunami K, Otsuka H. New diarylheptanoids from Amomum muricarpum Elmer. Chem Pharm Bull 2006 54 139-140 (Pubitemid 43036770)
15. Lee M W., Park M S., Jeong D W., Kim K H., Kim H H., Toh S H. Diarylheptanoids from the leaves of Alnus hirsute Turcz. Arch Pharm Res 2000 23 50-53
16. Smite E, Lundgren L N., Andersson R. Arylbutanoid and diarylheptanoid glycosides from inner bark of Betula pendula. Phytochemistry 1993 32 365-369
17. Gonzalez-Laredo R F., Chen J, Karchesy Y M., Karchesy J J. Four new diarylheptanoid glycosides from Alnus rubra bark. Nat Prod Lett 1999 13 75-80 (Pubitemid 29196968)
18. Regoli F, Winston G W. Quantification of total oxidant scavenging capacity of antioxidants for peroxynitrite, peroxyl radicals, and hydroxyl radicals. Toxicol Appl Pharmacol 1999 156 96-105 (Pubitemid 29196572)
19. Halliwell B, Aeschbach R, Loeliger J, Aruoma O I. The characterization of antioxidants. Food Chem Toxicol 1995 33 601-617
20. Kim S T., Kim J D., Ahn S H., Ahn G S., Lee Y I., Jeong Y S. Hepatoprotective and antioxidant effects of Alnus japonica extracts on acetaminophen-induced hepatotoxicity in rats. Phytother Res 2004 18 971-975
21. Modriansk M, Ulrichov J, Bachleda P, Anzenbacher P, Anzenbacherov E, Walterov D. Human hepatocyte-a model for toxicological studies. Functional and biochemical characterization. Gen Physiol Biophys 2000 19 223-235
22. Winston G W., Regoli F, Dugas A J., Fong J H., Blanchard K A. A rapid gas chromatographic assay for determining oxyradical scavenging capacity of antioxidants and biological fluids. Free Radic Biol Med 1998 24 480-493 (Pubitemid 28008793)
23. Park E J., Zhao Y Z., Kim Y C., Sohn D H. Protective effect of (S)-bakuchiol from Psoralea corylifolia on rat liver injury in vitro and in vivo. Planta Med 2005 71 508-513