Piceatannol, natural polyphenolic stilbene, inhibits adipogenesis via modulation of mitotic clonal expansion and insulin receptor-dependent insulin signaling in early phase of differentiation

Journal of Biological Chemistry

Volumn 287, Issue 14, 2012, Pages 11566-11578

  Kwon, Jung Yeon ^a   Seo, Sang Gwon ^b   Heo, Yong Seok ^c   Yue, Shuhua ^d   Cheng, Ji Xin ^a,d   Lee, Ki Won ^b   Kim, Kee Hong ^a  

^a PURDUE UNIVERSITY   (United States)

^b Seoul National University   (South Korea)

^c Konkuk University   (South Korea)

^d PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOGENESIS; ADIPOSE TISSUE; AFTER INITIATION; CELL CYCLE; CLONAL EXPANSION; DOSE-DEPENDENT MANNER; HEALTH BENEFITS; INSULIN RECEPTORS; INSULIN SIGNALING; KINASE ACTIVITY; KINETICS STUDIES; PHOSPHATIDYLINOSITOL 3-KINASE; PREADIPOCYTES; RESVERATROL; UNDERLYING MECHANISM;

ENZYMES; PHOSPHORYLATION; TISSUE;

INSULIN;

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PICEATANNOL; PROTEIN KINASE B;

ADIPOGENESIS; ARTICLE; BINDING AFFINITY; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL DIFFERENTIATION; CELL STRAIN 3T3; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING; DRUG MECHANISM; ENZYME INHIBITION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ADENOSINE TRIPHOSPHATE; ADIPOCYTES; ADIPOGENESIS; ANIMALS; CELL DIVISION; CELL SURVIVAL; GENE EXPRESSION REGULATION; INSULIN; MICE; MODELS, MOLECULAR; PHENOLS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; STILBENES; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 84859503387     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.259721     Document Type: Article

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