Cocoa polyphenols suppress adipogenesis in vitro and obesity in vivo by targeting insulin receptor

International Journal of Obesity

Volumn 37, Issue 4, 2013, Pages 584-592

  Min, S Y ^a   Yang, H ^a   Seo, S G ^a   Shin, S H ^a   Chung, M Y ^a,b   Kim, J ^a,b,c   Lee, S J ^a   Lee, H J ^a   Lee, K W ^a,b,c  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

adipogenesis; cocoa polyphenols; insulin receptor; mitotic clonal expansion

Indexed keywords

COCOA POLYPHENOL EXTRACT; DEXAMETHASONE; INSULIN; INSULIN RECEPTOR; ISOBUTYLMETHYLXANTHINE; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLANT EXTRACT; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADIPOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CACAO; CELL CYCLE PROGRESSION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG MEGADOSE; ENZYME BINDING; ENZYME PHOSPHORYLATION; LIPID DIET; LIPID STORAGE; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WEIGHT GAIN;

3T3-L1 CELLS; ADIPOGENESIS; ANIMALS; ANTI-OBESITY AGENTS; BLOTTING, WESTERN; CACAO; CELL PROLIFERATION; CELLS, CULTURED; DIET, HIGH-FAT; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; MALE; MICE; MICE, INBRED C57BL; OBESITY; PHOSPHORYLATION; POLYPHENOLS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN;

MUS; THEOBROMA CACAO;

EID: 84876185466     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2012.85     Document Type: Article

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