AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism

Cellular and Molecular Life Sciences

Volumn 65, Issue 23, 2008, Pages 3737-3755

  Witczak, C A ^a   Sharoff, C G ^b   Goodyear, L J ^a  

^a JOSLIN DIABETES CENTER   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Ca2+ calmodulin dependent protein kinase kinase; Carbohydrate; Glucose; Lipid; LKB1; Protein phosphatase; Transforming growth factor activated kinase 1

Indexed keywords

A 769662; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; ENZYME ACTIVATOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; PHOSPHOPROTEIN PHOSPHATASE; PIOGLITAZONE; PROTEIN KINASE LKB1; REACTIVE OXYGEN METABOLITE; ROSIGLITAZONE; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG;

CALCIUM CELL LEVEL; CELL METABOLISM; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; GLUCOSE METABOLISM; LIPID METABOLISM; LIPOLYSIS; MUSCLE CONTRACTION; MUSCLE EXCITATION; NON INSULIN DEPENDENT DIABETES MELLITUS; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN STRUCTURE; REVIEW; SKELETAL MUSCLE;

AMP-ACTIVATED PROTEIN KINASES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; ENERGY METABOLISM; GENE COMPONENTS; GLUCOSE; LIPID METABOLISM; MAP KINASE KINASE KINASES; MODELS, BIOLOGICAL; MUSCLE, SKELETAL; PROTEIN PHOSPHATASE 2; PROTEIN-SERINE-THREONINE KINASES;

EID: 57349094302     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-008-8244-6     Document Type: Review

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