Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-κB as a potential molecular target

FEBS Letters

Volumn 580, Issue 2, 2006, Pages 385-392

  Kim, Jung Hwan ^a   Lee, Ki Won ^a   Lee, Min Won ^b   Lee, Hyong Joo ^a   Kim, Sung Hoon ^c   Surh, Young Joon ^a  

^a Seoul National University   (South Korea)

^b Chung Ang University   (South Korea)

^c Kyung Hee University   (South Korea)

Author keywords

Cyclooxygenase 2; Hirsutenone; Human breast epithelial cells; Invasion; Matrix metalloproteinase 9; Migration; Nuclear factor kappa B

Indexed keywords

CYCLOOXYGENASE 2; GELATINASE B; HEPTANE DERIVATIVE; HIRSUTENONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL ESTER; PROSTAGLANDIN E2; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; TUMOR PROMOTER; UNCLASSIFIED DRUG;

ALDER; ARTICLE; BREAST EPITHELIUM; CONTROLLED STUDY; DNA BINDING; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; FATTY ACID SYNTHESIS; HUMAN; HUMAN CELL; MEDICINAL PLANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; UPREGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; CATECHOLS; CELL LINE; CELL MOVEMENT; CYCLOOXYGENASE 2; DIARYLHEPTANOIDS; DINOPROSTONE; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; HUMANS; MAMMARY GLANDS, HUMAN; MATRIX METALLOPROTEINASE 9; MEMBRANE PROTEINS; MOLECULAR STRUCTURE; NF-KAPPA B; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION, GENETIC; UP-REGULATION;

ALNUS HIRSUTA; BETULACEAE;

EID: 30644461913     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.12.015     Document Type: Article

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