-
1
-
-
33845602526
-
Hormonal induction of adipogenesis induces Skp2 expression through PI3K and MARK pathways
-
DOI 10.1002/jcb.21063
-
Auld CA, Caccia CD, Morrison RF (2007a) Hormonal induction of adipogenesis induces Skp2 expression through PI3K and MAPK pathways. J Cell Biochem 100: 204-216 (Pubitemid 44958191)
-
(2007)
Journal of Cellular Biochemistry
, vol.100
, Issue.1
, pp. 204-216
-
-
Auld, C.A.1
Caccia, C.D.2
Morrison, R.F.3
-
2
-
-
33847671842
-
2 phase progression of adipocyte hyperplasia
-
DOI 10.1002/jcp.20915
-
Auld CA, Fernandes KM, Morrison RF (2007b) Skp2-mediated p27(Kip1) degradation during S/G2 phase progression of adipocyte hyperplasia. J Cell Physiol 211: 101-111 (Pubitemid 46363899)
-
(2007)
Journal of Cellular Physiology
, vol.211
, Issue.1
, pp. 101-111
-
-
Auld, C.A.1
Fernandes, K.M.2
Morrison, R.F.3
-
3
-
-
77953530400
-
Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localization
-
Bashir T, Pagan JK, Busino L, Pagano M (2010) Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localization. Cell Cycle 9: 971-974
-
(2010)
Cell Cycle
, vol.9
, pp. 971-974
-
-
Bashir, T.1
Pagan, J.K.2
Busino, L.3
Pagano, M.4
-
4
-
-
34047095297
-
The Two TORCs and Akt
-
DOI 10.1016/j.devcel.2007.03.020, PII S1534580707001207
-
Bhaskar PT, Hay N (2007) The two TORCs and Akt. Dev Cell 12: 487-502 (Pubitemid 46523652)
-
(2007)
Developmental Cell
, vol.12
, Issue.4
, pp. 487-502
-
-
Bhaskar, P.T.1
Hay, N.2
-
5
-
-
70249146172
-
MTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition
-
Bhaskar PT, Nogueira V, Patra KC, Jeon SM, Park Y, Robey RB, Hay N (2009) mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition. Mol Cell Biol 29: 5136-5147
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5136-5147
-
-
Bhaskar, P.T.1
Nogueira, V.2
Patra, K.C.3
Jeon, S.M.4
Park, Y.5
Robey, R.B.6
Hay, N.7
-
6
-
-
77953494031
-
Phosphorylation of Ser72 does not regulate the ubiquitin ligase activity and subcellular localization of Skp2
-
Boutonnet C, Tanguay PL, Julien C, Rodier G, Coulombe P, Meloche S (2010) Phosphorylation of Ser72 does not regulate the ubiquitin ligase activity and subcellular localization of Skp2. Cell Cycle 9: 975-979
-
(2010)
Cell Cycle
, vol.9
, pp. 975-979
-
-
Boutonnet, C.1
Tanguay, P.L.2
Julien, C.3
Rodier, G.4
Coulombe, P.5
Meloche, S.6
-
7
-
-
34547200053
-
The F box protein S phase kinase-associated protein 2 regulates adipose mass and adipocyte number in vivo
-
Cooke PS, Holsberger DR, Cimafranca MA, Meling DD, Beals CM, Nakayama K, Nakayama KI, Kiyokawa H (2007) The F box protein S phase kinase-associated protein 2 regulates adipose mass and adipocyte number in vivo. Obesity (Silver Spring) 15: 1400-1408 (Pubitemid 47110903)
-
(2007)
Obesity
, vol.15
, Issue.6
, pp. 1400-1408
-
-
Cooke, P.S.1
Holsberger, D.R.2
Cimafranca, M.A.3
Meling, D.D.4
Beals, C.M.5
Nakayama, K.6
Nakayama, K.I.7
Kiyokawa, H.8
-
8
-
-
33750325725
-
S6k1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth
-
DOI 10.1126/science.1130276
-
Dorrello NV, Peschiaroli A, Guardavaccaro D, Colburn NH, Sherman NE, Pagano M (2006) S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science 314: 467-471 (Pubitemid 44628968)
-
(2006)
Science
, vol.314
, Issue.5798
, pp. 467-471
-
-
Dorrello, N.V.1
Peschiaroli, A.2
Guardavaccaro, D.3
Colburn, N.H.4
Sherman, N.E.5
Pagano, M.6
-
9
-
-
77952967459
-
MTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs
-
Dowling RJ, Topisirovic I, Alain T, Bidinosti M, Fonseca BD, Petroulakis E, Wang X, Larsson O, Selvaraj A, Liu Y, Kozma SC, Thomas G, Sonenberg N (2010) mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. Science 328: 1172-1176
-
(2010)
Science
, vol.328
, pp. 1172-1176
-
-
Dowling, R.J.1
Topisirovic, I.2
Alain, T.3
Bidinosti, M.4
Fonseca, B.D.5
Petroulakis, E.6
Wang, X.7
Larsson, O.8
Selvaraj, A.9
Liu, Y.10
Kozma, S.C.11
Thomas, G.12
Sonenberg, N.13
-
10
-
-
0032793068
-
Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: Implications for adipocyte differentiation and metabolism
-
Fajas L, Schoonjans K, Gelman L, Kim JB, Najib J, Martin G, Fruchart JC, Briggs M, Spiegelman BM, Auwerx J (1999) Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism. Mol Cell Biol 19: 5495-5503
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5495-5503
-
-
Fajas, L.1
Schoonjans, K.2
Gelman, L.3
Kim, J.B.4
Najib, J.5
Martin, G.6
Fruchart, J.C.7
Briggs, M.8
Spiegelman, B.M.9
Auwerx, J.10
-
11
-
-
44349122993
-
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: Tipping the scales of cancer
-
DOI 10.1038/nrc2396, PII NRC2396
-
Frescas D, Pagano M (2008) Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer. Nat Rev Cancer 8: 438-449 (Pubitemid 351744963)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.6
, pp. 438-449
-
-
Frescas, D.1
Pagano, M.2
-
12
-
-
77956275419
-
EIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression
-
Furic L, Rong L, Larsson O, Koumakpayi IH, Yoshida K, Brueschke A, Petroulakis E, Robichaud N, Pollak M, Gaboury LA, Pandolfi PP, Saad F, Sonenberg N (2010) eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression. Proc Natl Acad Sci USA 107: 14134-14139
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14134-14139
-
-
Furic, L.1
Rong, L.2
Larsson, O.3
Koumakpayi, I.H.4
Yoshida, K.5
Brueschke, A.6
Petroulakis, E.7
Robichaud, N.8
Pollak, M.9
Gaboury, L.A.10
Pandolfi, P.P.11
Saad, F.12
Sonenberg, N.13
-
13
-
-
64049086572
-
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction
-
Gao D, Inuzuka H, Tseng A, Chin RY, Toker A, Wei W (2009) Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. Nat Cell Biol 11: 397-408
-
(2009)
Nat Cell Biol
, vol.11
, pp. 397-408
-
-
Gao, D.1
Inuzuka, H.2
Tseng, A.3
Chin, R.Y.4
Toker, A.5
Wei, W.6
-
14
-
-
2542528670
-
A family with severe insulin resistance and diabetes due to a mutation in AKT2
-
DOI 10.1126/science.1096706
-
George S, Rochford JJ, Wolfrum C, Gray SL, Schinner S, Wilson JC, Soos MA, Murgatroyd PR, Williams RM, Acerini CL, Dunger DB, Barford D, Umpleby AM, Wareham NJ, Davies HA, Schafer AJ, Stoffel M, O'Rahilly S, Barroso I (2004) A family with severe insulin resistance and diabetes due to a mutation in AKT2. Science 304: 1325-1328 (Pubitemid 38697429)
-
(2004)
Science
, vol.304
, Issue.5675
, pp. 1325-1328
-
-
George, S.1
Rochford, J.J.2
Wolfrum, C.3
Gray, S.L.4
Schinner, S.5
Wilson, J.C.6
Soos, M.A.7
Murgatroyd, P.R.8
Williams, R.M.9
Acerini, C.L.10
Dunger, D.B.11
Barford, D.12
Umpleby, A.M.13
Wareham, N.J.14
Davies, H.A.15
Schafer, A.J.16
Stoffel, M.17
O'Rahilly, S.18
Barroso, I.19
-
15
-
-
4043171462
-
Upstream and downstream of mTOR
-
DOI 10.1101/gad.1212704
-
Hay N, Sonenberg N (2004) Upstream and downstream of mTOR. Genes Dev 18: 1926-1945 (Pubitemid 39071573)
-
(2004)
Genes and Development
, vol.18
, Issue.16
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
16
-
-
0032516081
-
ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand
-
DOI 10.1073/pnas.95.8.4333
-
Kim JB, Wright HM, Wright M, Spiegelman BM (1998) ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand. Proc Natl Acad Sci USA 95: 4333-4337 (Pubitemid 28207912)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.8
, pp. 4333-4337
-
-
Kim, J.B.1
Wright, H.M.2
Wright, M.3
Spiegelman, B.M.4
-
17
-
-
0036010603
-
Novel adipocyte lines from brown fat: A model system for the study of differentiation, energy metabolism, and insulin action
-
DOI 10.1002/bies.10058
-
Klein J, Fasshauer M, Klein HH, Benito M, Kahn CR (2002) Novel adipocyte lines from brown fat: a model system for the study of differentiation, energy metabolism, and insulin action. Bioessays 24: 382-388 (Pubitemid 34305693)
-
(2002)
BioEssays
, vol.24
, Issue.4
, pp. 382-388
-
-
Klein, J.1
Fasshauer, M.2
Klein, H.H.3
Benito, M.4
Ronald, K.C.5
-
18
-
-
70350418625
-
MTOR signaling at a glance
-
Laplante M, Sabatini DM (2009) mTOR signaling at a glance. J Cell Sci 122: 3589-3594
-
(2009)
J Cell Sci
, vol.122
, pp. 3589-3594
-
-
Laplante, M.1
Sabatini, D.M.2
-
19
-
-
0034845958
-
PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
-
Lawlor MA, Alessi DR (2001) PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J Cell Sci 114: 2903-2910 (Pubitemid 32821530)
-
(2001)
Journal of Cell Science
, vol.114
, Issue.16
, pp. 2903-2910
-
-
Lawlor, M.A.1
Alessi, D.R.2
-
20
-
-
33846806078
-
Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2
-
DOI 10.1172/JCI29528
-
Le Bacquer O, Petroulakis E, Paglialunga S, Poulin F, Richard D, Cianflone K, Sonenberg N (2007) Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2. J Clin Invest 117: 387-396 (Pubitemid 46203967)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.2
, pp. 387-396
-
-
Le, B.O.1
Petroulakis, E.2
Paglialunga, S.3
Poulin, F.4
Richard, D.5
Cianflone, K.6
Sonenberg, N.7
-
21
-
-
64049087382
-
Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB
-
Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, Chan CH, Yang WL, Erdjument-Bromage H, Nakayama KI, Nimer S, Tempst P, Pandolfi PP (2009) Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. Nat Cell Biol 11: 420-432
-
(2009)
Nat Cell Biol
, vol.11
, pp. 420-432
-
-
Lin, H.K.1
Wang, G.2
Chen, Z.3
Teruya-Feldstein, J.4
Liu, Y.5
Chan, C.H.6
Yang, W.L.7
Erdjument-Bromage, H.8
Nakayama, K.I.9
Nimer, S.10
Tempst, P.11
Pandolfi, P.P.12
-
22
-
-
14844317298
-
Atypical transcriptional regulators and cofactors of PPARgamma
-
DOI 10.1038/sj.ijo.0802906
-
Miard S, Fajas L (2005) Atypical transcriptional regulators and cofactors of PPARgamma. Int J Obes (Lond) 29(Suppl 1): S10-S12 (Pubitemid 40343164)
-
(2005)
International Journal of Obesity
, vol.29
, Issue.SUPPL. 1
-
-
Miard, S.1
Fajas, L.2
-
23
-
-
10044265249
-
Loss of cyclin-dependent kinase inhibitors produces adipocyte hyperplasia and obesity
-
DOI 10.1096/fj.04-2631fje
-
Naaz A, Holsberger DR, Iwamoto GA, Nelson A, Kiyokawa H, Cooke PS (2004) Loss of cyclin-dependent kinase inhibitors produces adipocyte hyperplasia and obesity. FASEB J 18: 1925-1927 (Pubitemid 39602286)
-
(2004)
FASEB Journal
, vol.18
, Issue.15
, pp. 1925-1927
-
-
Naaz, A.1
Holsberger, D.R.2
Iwamoto, G.A.3
Nelson, A.4
Kiyokawa, H.5
Cooke, P.S.6
-
24
-
-
2342650733
-
Skp2-Mediated degradation of p27 regulates progression into mitosis
-
DOI 10.1016/S1534-5807(04)00131-5, PII S1534580704001315
-
Nakayama K, Nagahama H, Minamishima YA, Miyake S, Ishida N, Hatakeyama S, Kitagawa M, Iemura S, Natsume T, Nakayama KI (2004) Skp2-mediated degradation of p27 regulates progression into mitosis. Dev Cell 6: 661-672 (Pubitemid 38579350)
-
(2004)
Developmental Cell
, vol.6
, Issue.5
, pp. 661-672
-
-
Nakayama, K.1
Nagahama, H.2
Minamishima, Y.A.3
Miyake, S.4
Ishida, N.5
Hatakeyama, S.6
Kitagawa, M.7
Iemura, S.-I.8
Natsume, T.9
Nakayama, K.I.10
-
25
-
-
17044370346
-
Regulation of the cell cycle by SCF-type ubiquitin ligases
-
Nakayama KI, Nakayama K (2005) Regulation of the cell cycle by SCF-type ubiquitin ligases. Semin Cell Dev Biol 16: 323-333
-
(2005)
Semin Cell Dev Biol
, vol.16
, pp. 323-333
-
-
Nakayama, K.I.1
Nakayama, K.2
-
26
-
-
56849118516
-
Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis
-
Nogueira V, Park Y, Chen CC, Xu PZ, Chen ML, Tonic I, Unterman T, Hay N (2008) Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis. Cancer Cell 14: 458-470
-
(2008)
Cancer Cell
, vol.14
, pp. 458-470
-
-
Nogueira, V.1
Park, Y.2
Chen, C.C.3
Xu, P.Z.4
Chen, M.L.5
Tonic, I.6
Unterman, T.7
Hay, N.8
-
27
-
-
2442515980
-
Control of DNA synthesis and mitosis by the Skp2-p27-Cdk1/2 axis
-
Pagano M (2004) Control of DNA synthesis and mitosis by the Skp2-p27-Cdk1/2 axis. Mol Cell 14: 414-416
-
(2004)
Mol Cell
, vol.14
, pp. 414-416
-
-
Pagano, M.1
-
28
-
-
0034625418
-
Mitotic clonal expansion during preadipocyte differentiation: Calpain- mediated turnover of p27
-
DOI 10.1074/jbc.M910445199
-
Patel YM, Lane MD (2000) Mitotic clonal expansion during preadipocyte differentiation: calpain-mediated turnover of p27. J Biol Chem 275: 17653-17660 (Pubitemid 30430813)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.23
, pp. 17653-17660
-
-
Patel, Y.M.1
Lane, M.D.2
-
29
-
-
0038624395
-
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2
-
Peng XD, Xu PZ, Chen ML, Hahn-Windgassen A, Skeen J, Jacobs J, Sundararajan D, Chen WS, Crawford SE, Coleman KG, Hay N (2003) Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes Dev 17: 1352-1365 (Pubitemid 36666005)
-
(2003)
Genes and Development
, vol.17
, Issue.11
, pp. 1352-1365
-
-
Peng, X.-D.1
Xu, P.-Z.2
Chen, M.-L.3
Hahn-Windgassen, A.4
Skeen, J.5
Jacobs, J.6
Sundararajan, D.7
Chen, W.S.8
Crawford, S.E.9
Coleman, K.G.10
Hay, N.11
-
30
-
-
70350494540
-
P53-dependent translational control of senescence and transformation via 4E-BPs
-
Petroulakis E, Parsyan A, Dowling RJ, LeBacquer O, Martineau Y, Bidinosti M, Larsson O, Alain T, Rong L, Mamane Y, Paquet M, Furic L, Topisirovic I, Shahbazian D, Livingstone M, Costa-Mattioli M, Teodoro JG, Sonenberg N (2009) p53-dependent translational control of senescence and transformation via 4E-BPs. Cancer Cell 16: 439-446
-
(2009)
Cancer Cell
, vol.16
, pp. 439-446
-
-
Petroulakis, E.1
Parsyan, A.2
Dowling, R.J.3
LeBacquer, O.4
Martineau, Y.5
Bidinosti, M.6
Larsson, O.7
Alain, T.8
Rong, L.9
Mamane, Y.10
Paquet, M.11
Furic, L.12
Topisirovic, I.13
Shahbazian, D.14
Livingstone, M.15
Costa-Mattioli, M.16
Teodoro, J.G.17
Sonenberg, N.18
-
31
-
-
42449138319
-
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy
-
DOI 10.1083/jcb.200710215
-
Ramirez-Valle F, Braunstein S, Zavadil J, Formenti SC, Schneider RJ (2008) eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy. J Cell Biol 181: 293-307 (Pubitemid 351574554)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.2
, pp. 293-307
-
-
Ramirez-Valle, F.1
Braunstein, S.2
Zavadil, J.3
Formenti, S.C.4
Schneider, R.J.5
-
32
-
-
60549111398
-
Is Akt the 'Warburg kinase'?-Akt-energy metabolism interactions and oncogenesis
-
Robey RB, Hay N (2009) Is Akt the 'Warburg kinase'?-Akt-energy metabolism interactions and oncogenesis. Semin Cancer Biol 19: 25-31
-
(2009)
Semin Cancer Biol
, vol.19
, pp. 25-31
-
-
Robey, R.B.1
Hay, N.2
-
33
-
-
33845325476
-
Adipocyte differentiation from the inside out
-
DOI 10.1038/nrm2066, PII NRM2066
-
Rosen ED, MacDougald OA (2006) Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 7: 885-896 (Pubitemid 44871415)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.12
, pp. 885-896
-
-
Rosen, E.D.1
MacDougald, O.A.2
-
34
-
-
0033213631
-
PPARgamma is required for the differentiation of adipose tissue in vivo and in vitro
-
DOI 10.1016/S1097-2765(00)80211-7
-
Rosen ED, Sarraf P, Troy AE, Bradwin G, Moore K, Milstone DS, Spiegelman BM, Mortensen RM (1999) PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell 4: 611-617 (Pubitemid 29531140)
-
(1999)
Molecular Cell
, vol.4
, Issue.4
, pp. 611-617
-
-
Rosen, E.D.1
Sarraf, P.2
Troy, A.E.3
Bradwin, G.4
Moore, K.5
Milstone, D.S.6
Spiegelman, B.M.7
Mortensen, R.M.8
-
35
-
-
0035851187
-
PPARgamma: A nuclear regulator of metabolism, differentiation, and cell growth
-
Rosen ED, Spiegelman BM (2001) PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem 276: 37731-37734
-
(2001)
J Biol Chem
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
36
-
-
0034214246
-
Transcriptional regulation of adipogenesis
-
Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM (2000) Transcriptional regulation of adipogenesis. Genes Dev 14: 1293-1307 (Pubitemid 30397073)
-
(2000)
Genes and Development
, vol.14
, Issue.11
, pp. 1293-1307
-
-
Rosen, E.D.1
Walkey, C.J.2
Puigserver, P.3
Spiegelman, B.M.4
-
37
-
-
33847250516
-
Skp2 controls adipocyte proliferation during the development of obesity
-
DOI 10.1074/jbc.M608144200
-
Sakai T, Sakaue H, Nakamura T, Okada M, Matsuki Y, Watanabe E, Hiramatsu R, Nakayama K, Nakayama KI, Kasuga M (2007) Skp2 controls adipocyte proliferation during the development of obesity. J Biol Chem 282: 2038-2046 (Pubitemid 47076733)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.3
, pp. 2038-2046
-
-
Sakai, T.1
Sakaue, H.2
Nakamura, T.3
Okada, M.4
Matsuki, Y.5
Watanabe, E.6
Hiramatsu, R.7
Nakayama, K.8
Nakayama, K.I.9
Kasuga, M.10
-
38
-
-
33749430399
-
Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner
-
DOI 10.1016/j.ccr.2006.08.022, PII S1535610806002789
-
Skeen JE, Bhaskar PT, Chen CC, Chen WS, Peng XD, Nogueira V, Hahn-Windgassen A, Kiyokawa H, Hay N (2006) Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner. Cancer Cell 10: 269-280 (Pubitemid 44512190)
-
(2006)
Cancer Cell
, vol.10
, Issue.4
, pp. 269-280
-
-
Skeen, J.E.1
Bhaskar, P.T.2
Chen, C.-C.3
Chen, W.S.4
Peng, X.-d.5
Nogueira, V.6
Hahn-Windgassen, A.7
Kiyokawa, H.8
Hay, N.9
-
40
-
-
77956271160
-
Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development
-
Ueda T, Sasaki M, Elia AJ, Chio II, Hamada K, Fukunaga R, Mak TW (2010) Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development. Proc Natl Acad Sci USA 107: 13984-13990
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 13984-13990
-
-
Ueda, T.1
Sasaki, M.2
Elia, A.J.3
Chio, I.I.4
Hamada, K.5
Fukunaga, R.6
Mak, T.W.7
-
41
-
-
77953519397
-
A comparison between Skp2 and FOXO1 for their cytoplasmic localization by Akt1
-
Wang H, Cui J, Bauzon F, Zhu L (2010) A comparison between Skp2 and FOXO1 for their cytoplasmic localization by Akt1. Cell Cycle 9: 1021-1022
-
(2010)
Cell Cycle
, vol.9
, pp. 1021-1022
-
-
Wang, H.1
Cui, J.2
Bauzon, F.3
Zhu, L.4
-
42
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg RA (1995) The retinoblastoma protein and cell cycle control. Cell 81: 323-330
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
43
-
-
0033083803
-
Cross-regulation of C/EBPalpha and PPARgamma controls the transcriptional pathway of adipogenesis and insulin sensitivity
-
DOI 10.1016/S1097-2765(00)80306-8
-
Wu Z, Rosen ED, Brun R, Hauser S, Adelmant G, Troy AE, McKeon C, Darlington GJ, Spiegelman BM (1999) Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol Cell 3: 151-158 (Pubitemid 29292616)
-
(1999)
Molecular Cell
, vol.3
, Issue.2
, pp. 151-158
-
-
Wu, Z.1
Rosen, E.D.2
Brun, R.3
Hauser, S.4
Adelmant, G.5
Troy, A.E.6
McKeon, C.7
Darlington, G.J.8
Spiegelman, B.M.9
-
44
-
-
67650523945
-
Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway
-
Zhang HH, Huang J, Duvel K, Boback B, Wu S, Squillace RM, Wu CL, Manning BD (2009) Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway. PLoS One 4: e6189
-
(2009)
PLoS One
, vol.4
-
-
Zhang, H.H.1
Huang, J.2
Duvel, K.3
Boback, B.4
Wu, S.5
Squillace, R.M.6
Wu, C.L.7
Manning, B.D.8
|