3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin Analogues with antiproliferative activity

Marine Drugs

Volumn 13, Issue 4, 2015, Pages 1901-1924

  Parrino, Barbara ^a   Carbone, Anna ^a   Di Vita, Gloria ^a   Ciancimino, Cristina ^a   Attanzio, Alessandro ^a   Spanò, Virginia ^a   Montalbano, Alessandra ^a   Barraja, Paola ^a   Tesoriere, Luisa ^a   Livrea, Maria Antonia ^a   Diana, Patrizia ^a   Cirrincione, Girolamo ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

3 4 (1H indol 3 yl) 1,3 thiazol 2 yl 1H pyrrolo 2,3 b pyridines; Antiproliferative activity; Indolyl alkaloids; Marine alkaloids; Nortopsentin analogues

Indexed keywords

1 METHYL 3 [4 (1 METHYL 1H INDOL 3 YL) 1,3 THIAZOL 2 YL] 1H PYRROLO[2,3 B]PYRIDINE; 1 METHYL 3 [4 [1 [(4 METHYLPHENYL)SULFONYL] 1H INDOL 3 YL] 1,3 THIAZOL 2 YL] 1H PYRROLO [2,3 B]PYRIDINE; 3 [4 (1 METHYL 1H INDOL 3 YL) 1,3 THIAZOL 2 YL] 1H PYRROLO[2,3 B]PYRIDINE; 3 [4 (1H INDOL 3 YL) 1,3 THIAZOL 2 YL] 1 METHYL 1H PYRROLO[2,3 B]PYRIDINE; 3 [4 (1H INDOL 3 YL) 1,3 THIAZOL 2 YL] 1H PYRROLO[2,3 B]PYRIDINE; 3 [4 (1H INDOL 3 YL) 1,3 THIAZOL 2 YL] 1H PYRROLO[2,3 B]PYRIDINE DERIVATIVE; 3 [4 (5 FLUORO 1 METHYL 1H INDOL 3 YL) 1,3 THIAZOL 2 YL] 1 METHYL 1H PYRROLO[2,3 B]PYRIDINE; 3 [4 (5 FLUORO 1 METHYL 1H INDOL 3 YL) 1,3 THIAZOL 2 YL] 1H PYRROLO[2,3 B]PYRIDINE; 3 [4 (5 FLUORO 1H INDOL 3 YL) 1,3 THIAZOL 2 YL] 1H PYRROLO[2,3 B]PYRIDINE; 3 [4 (5 FLUORO 1H INDOL 3 YL) 1,3 THIAZOL 2 YL] 1METHYL 1H PYRROLO[2,3 B]PYRIDINE; 3 [4 [1 [(4 METHYLPHENYL)SULFONYL] 1H INDOL 3 YL] 1,3 THIAZOL 2 YL] 1H PYRROLO [2,3 B]PYRIDINE; 3 [4 [5 FLUORO 1 [(4-METHYLPHENYL)SULFONYL] 1H INDOL 3 YL] 1,3 THIAZOL 2 YL] 1 METHYL 1H PYRROLO (2,3 B)PYRIDINE; 3 [4 [5 FLUORO 1 [(4-METHYLPHENYL)SULFONYL] 1H INDOL 3 YL] 1,3 THIAZOL 2 YL] 1 METHYL 1H PYRROLO [2,3 B]PYRIDINE; 3 [4 [5 FLUORO 1 [(4-METHYLPHENYL)SULFONYL] 1H INDOL 3 YL] 1,3 THIAZOL 2 YL] 1H PYRROLO [2,3 B]PYRIDINE; ANTINEOPLASTIC AGENT; NORTOPSENTIN DERIVATIVE; PHOSPHATIDYLSERINE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; ALKALOID; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; PYRROLE DERIVATIVE; THIAZOLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER CELL LINE; CANCER CELL LINE; CELL VIABILITY; CENTRAL NERVOUS SYSTEM TUMOR; CHEMICAL MODIFICATION; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; HEPATOCELLULAR CARCINOMA CELL LINE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LUNG CANCER CELL LINE; MELANOMA CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; NON SMALL CELL LUNG CANCER; OVARIAN CANCER CELL LINE; PROSTATE CANCER CELL LINE; RENAL CANCER CELL LINE; CELL CYCLE G0 PHASE; CELL CYCLE G2 PHASE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG DESIGN; DRUG EFFECTS; HALOGENATION; METHYLATION; MITOCHONDRION; NEOPLASMS; PATHOLOGY; SYNTHESIS; TUMOR CELL LINE;

ALKALOIDS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG DESIGN; G0 PHASE; G2 PHASE; HALOGENATION; HUMANS; IMIDAZOLES; INDOLES; MEMBRANE POTENTIAL, MITOCHONDRIAL; METHYLATION; MITOCHONDRIA; MOLECULAR STRUCTURE; NEOPLASMS; PYRIDINES; PYRROLES; THIAZOLES;

EID: 84928501009     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md13041901     Document Type: Article

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