Synthesis and antiproliferative activity of substituted 3[2-(1h-indol-3-yl)- 1,3-thiazol-4-yl]-1h-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues

Current Medicinal Chemistry

Volumn 21, Issue 14, 2014, Pages 1654-1666

  Carbone, A ^a   Pennati, M ^b   Barraja, P ^a   Montalbano, A ^a   Parrino, B ^a   Spano V ^a   Lopergolo, A ^b   Sbarra, S ^b   Doldi, V ^b   Zaffaroni, N ^b   Cirrincione, G ^a   Diana, P ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Antiproliferative activity; CDK1 inhibitors; Diffuse malignant peritoneal mesothelioma; Indolyl 4 azaindolyl thiazoles; Nortopsentin analogues; Survivin

Indexed keywords

ALKALOID DERIVATIVE; CYCLIN DEPENDENT KINASE INHIBITOR; NORTOPSENTIN DERIVATIVE; PACLITAXEL; SURVIVIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL LINE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENTIATION; DRUG SYNTHESIS; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; PERITONEUM MESOTHELIOMA; APOPTOSIS; CELL LINE; CELL PROLIFERATION; DRUG EFFECTS; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE; CELL PROLIFERATION; HUMANS; PROTEIN KINASE INHIBITORS; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84899857869     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/09298673113206660307     Document Type: Article

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