An efficient synthesis of pyrrolo[3′,2′:4,5]thiopyrano[3,2-b] pyridin-2-one: A new ring system of pharmaceutical interest

Tetrahedron

Volumn 68, Issue 25, 2012, Pages 5087-5094

  Barraja, Paola ^a   Diana, Patrizia ^a   Spanò, Virginia ^a   Montalbano, Alessandra ^a   Carbone, Anna ^a   Parrino, Barbara ^a   Cirrincione, Girolamo ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

Angelicin; Antiproliferative activity; Enaminoketones; Pyrrolo 3 ,2 :4,5 thiopyrano 3,2 b pyridin 2 one

Indexed keywords

1 BENZYL 2 METHYL 1,7 DIHYDROTHIOPYRANO [3,4 BETA] PYRROL 4(5H) ONE; 1 BENZYL 5 [(DIMETHYLAMINO) METHYLIDENE] 2 METHYL 1,7 DIHYDROTHIOPYRANO [3,4 BETA] PYRROL 4(5H) ONE; 1(4 METHOXYBENZYL) 2 METHYL 1,7 DIHYDROTHIOPYRANO [3,4 BETA] PYRROL 4(5H) ONE; 1,2 DIMETHYL 1,7 DIHYDROTHIOPYRANO [3,4 BETA] PYRROL 4(5H) ONE; 2 CYANOACETOPHENONE; 2 METHYL 1 PHENYL 1,7 DIHYDROTHIOPYRANO [3,4 BETA] PYRROL 4(5H) ONE; 2 METHYL 1(4 METHYLBENZYL) 1,7 DIHYDROTHIOPYRANO [3,4 BETA] PYRROL 4(5H) ONE; 2 METHYL 1,7 DIHYDROTHIOPYRANO [3,4 BETA] PYRROL 4(5H) ONE; 4(2 OXOPROPYL) 2H THIOPYRAN (4H,6H) 3,5 DIONE; 5 [(DIMETHYLAMINO) METHYLIDENE] 1,2 DIMETHYL 1,7 DIHYDROTHIOPYRANO [3,4 BETA] PYRROL 4(5H) ONE; 5 [(DIMETHYLAMINO) METHYLIDENE] 2 METHYL 1,7 DIHYDROTHIOPYRANO [3,4 B] PYRROL 4(5H) ONE; ACETONITRILE; CARBENE; CYANOMETHYLENE; ENAMINOKETONE DERIVATIVE; ETHYL 1 BENZYL 3 METHY 4 OXO 1,4,5,7 TETRAHYDROTHIOPYRANO [3,4 BETA] PYRROLE 2 CARBOXYLATE; ETHYL 1 BENZYL 5 [(DIMETHYLAMINO) METHYLIDENE] 3 METHYL 4 OXO 1,4,5,7 TETRAHYDROTHIOPYRANO [3,4 BETA] PYRROLE 2 CARBOXYLATE; ETHYL 1(4 METHOXYBENZYL) 3 METHYL 4 OXO 1,4,5,7 TETRAHYDROTHIOPYRANO [3,4 BETA] PYRROLE 2 CARBOXYLATE; ETHYL 1,3 DIMETHYL 4 OXO 1,4,5,7 TETRAHYDROTHIOPYRANO [3,4 B] PYRROLE 2 CARBOXYLATE; ETHYL 3 METHYL 1(4 METHYLBENZYL) 4 OXO 1,4,5,7 TETRAHYDROTHIOPYRANO [3,4 BETA] PYRROLE 2 CARBOXYLATE; ETHYL 3 METHYL 4 OXO 1,4,5,7 TETRAHYDROTHIOPYRANO [3,4 BETA] PYRROLE 2 CARBOXYLATE; ETHYL 5 [(DIMETHYLAMINO) METHYLIDENE] 3 METHYL 4 OXO 1,4,5,7 TETRAHYDROTHIOPYRANO [3,4 BETA] PYRROLE 2 CARBOXYLATE; ETHYL 5 [(DIMETHYLAMINO)METHYLIDENE] 1,3 DIMETHYL 4 OXO 1,4,5,7 TETRAHYDROTHIOPYRANO [3,4 B] PYRROLE 2 CARBOXYLATE; KETONE; MALONONITRILE; PHENYLSULFONYLACETONITRILE; PYRIDINE DERIVATIVE; PYRROLO [3',2' 4,5] THIOPYRANO [3,2 BETA] PYRIDIN 2 ONE; SULFUR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER INHIBITION; CONCENTRATION RESPONSE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TUMOR CELL LINE;

EID: 84861527373     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2012.04.041     Document Type: Article

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