Pyrrolo[3,4-h]quinolinones a new class of photochemotherapeutic agents

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 7, 2011, Pages 2326-2341

  Barraja, Paola ^a   Diana, Patrizia ^a   Montalbano, Alessandra ^a   Carbone, Anna ^a   Viola, Giampietro ^b   Basso, Giuseppe ^b   Salvador, Alessia ^b   Vedaldi, Daniela ^b   Dall'Acqua, Francesco ^b   Cirrincione, Girolamo ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

Angelicin heteroanalogues; Photochemotherapy; Phototoxicity; Pyrrolo 3,4 h quinolinones

Indexed keywords

2 BENZYL 5 (HYDROXYMETHYLENE) 2,5,6,7 TETRAHYDRO 4H ISOINDOL 4 ONE; 2 BENZYL 5 (HYDROXYMETHYLENE) 3 METHYL 2,5,6,7 TETRAHYDRO 4H ISOINDOL 4 ONE; 2 BENZYL 5 [(DIETHYLAMINO)METHYLENE] 2,5,6,7 TETRAHYDRO 4H ISOINDOL 4 ONE; 2 BENZYL 5 [(DIETHYLAMINO)METHYLENE] 3 METHYL 2,5,6,7 TETRAHYDRO 4H ISOINDOL 4 ONE; 5 (HYDROXYMETHYLENE) 2 METHYL 2,5,6,7 TETRAHYDRO 4H ISOINDOL 4 ONE; 5 (HYDROXYMETHYLENE) 2 PHENYL 2,5,6,7 TETRAHYDRO 4H ISOINDOL 4 ONE; 5 (HYDROXYMETHYLENE) 2,3 DIMETHYL 2,5,6,7 TETRAHYDRO 4H ISOINDOL 4 ONE; 5 [(DIETHYLAMINO)METHYLENE] 2 METHYL 2,5,6,7 TETRAHYDRO 4H ISOINDOL 4 ONE; 5 [(DIETHYLAMINO)METHYLENE] 2 PHENYL 2,5,6,7 TETRAHYDRO 4H ISOINDOL 4 ONE; 5 [(DIETHYLAMINO)METHYLENE] 2,3 DIMETHYL 2,5,6,7 TETRAHYDRO 4H ISOINDOL 4 ONE; 5 [(DIETHYLAMINO)METHYLENE] 2,5,6,7 TETRAHYDRO 4H ISOINDOL 4 ONE; 8 BENZYL 3 (PHENYLSULFONYL) 1,5,6,8 TETRAHYDRO 2H PYRROLO[3,4 H]QUINOLIN 2 ONE; 8 BENZYL 9 METHYL 3 (PHENYLSULFONYL) 1,5,6,8 TETRAHYDRO 2H PYRROLO[3,4 H]QUINOLIN 2 ONE; 8 METHYL 3 (PHENYLSULFONYL) 1,5,6,8 TETRAHYDRO 2H PYRROLO[3,4 H]QUINOLIN 2 ONE; 8 PHENYL 3 (PHENYLSULFONYL) 1,5,6,8 TETRAHYDRO 2H PYRROLO[3,4 H]QUINOLIN 2 ONE; 8,9 DIMETHYL 3 (PHENYLSULFONYL) 1,5,6,8 TETRAHYDRO 2H PYRROLO[3,4 H]QUINOLIN 2 ONE; 8,9 DIMETHYL 3 (PHENYLSULFONYL) 1,5,6,8 TETRAHYDRO 2H PYRROLO[3,4 H]QUINOLINE 2 ONE 7 CARBOXYLIC ACID; 9 METHYL 3 (PHENYLSULFONYL) 1,5,6,8 TETRAHYDRO 2H PYRROLO[3,4 H]QUINOLINE 2 ONE 7 CARBOXYLIC ACID DERIVATIVE; ANGELICIN; ETHYL 2 BENZYL 5 [(DIETHYLAMINO)METHYLENE] 3 METHYL 4 OXO 4,5,6,7 TETRAHYDRO 2H ISOINDOLE 1 CARBOXYLATE; ETHYL 5 [(DIETHYLAMINO)METHYLENE] 2,3 DIMETHYL 4 OXO 4,5,6,7 TETRAHYDRO 2H ISOINDOLE 1 CARBOXYLATE; ETHYL 5 [(DIETHYLAMINO)METHYLENE] 3 METHYL 4 OXO 4,5,6,7 TETRAHYDRO 2H ISOINDOLE 1 CARBOXYLATE; ETHYL 8 BENZYL 9 METHYL 3 (PHENYLSULFONYL) 1,5,6,8 TETRAHYDRO 2H PYRROLO[3,4 H]QUINOLINE 2 ONE 7 CARBOXYLATE; ETHYL 8,9 DMETHYL 3 (PHENYLSULFONYL) 1,5,6,8 TETRAHYDRO 2H PYRROLO[3,4 H]QUINOLINE 2 ONE 7 CARBOXYLATE; ETHYL 9 METHYL 3 (PHENYLSULFONYL) 1,5,6,8 TETRAHYDRO 2H PYRROLO[3,4 H]QUINOLINE 2 ONE 7 CARBOXYLATE; PHOTOSENSITIZING AGENT; PYRROLE DERIVATIVE; PYRROLO[3,4 H]QUINOLINONE DERIVATIVE; PYRROLOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; LIPID MEMBRANE; LIPID PEROXIDATION; LYSOSOME; PHOTOBIOLOGY;

CELL CYCLE; CELL LINE, TUMOR; DNA; FLUOROMETRY; HL-60 CELLS; HUMANS; JURKAT CELLS; LIPID PEROXIDATION; PHOSPHATIDYLSERINES; PHOTOCHEMICAL PROCESSES; PHOTOCHEMOTHERAPY; PYRROLES; QUINOLONES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBCELLULAR FRACTIONS;

EID: 79953200428     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.02.023     Document Type: Article

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