New bisindole alkaloids of the topsentin and hamacanthin classes from the Mediterranean marine sponge Rhaphisia lacazei

Journal of Natural Products

Volumn 63, Issue 4, 2000, Pages 447-451

  Casapullo, Agostino ^a   Bifulco, Giuseppe ^a   Bruno, Ines ^a   Riccio, Raffaele ^a  

^a UNIVERSITY OF SALERNO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DIHDYROHAMACANTHIN A; 3,4 DIHYDROHAMACANTHIN B; 6' DEBROMO 3,4 DIHYDROHAMACANTHIN A; 6' DEBROMO 3,4 DIHYDROHAMACANTHIN B; 6'' DEBROMO 3,4 DIHYDROHAMACANTHIN A; 6'' DEOXY BROMOTOPSENTIN; ANTINEOPLASTIC AGENT; ETHER; HAMACANTHIN; INDOLE ALKALOID; TOPSENTIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOASSAY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CARCINOMA; OPTICAL DENSITY; RHAPHISIA LACAZEI; SPONGE (PORIFERA);

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG SCREENING ASSAYS, ANTITUMOR; IMIDAZOLES; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; PIPERAZINES; PORIFERA; SPECTROPHOTOMETRY, ULTRAVIOLET; TISSUE EXTRACTS; TUMOR CELLS, CULTURED;

PORIFERA; RHAPHISIA; RHAPHISIA LACAZEI;

EID: 0034098001     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np9903292     Document Type: Article

References (20)

1. Christophersen, C. In The Alkaloids; Brossi, A., Ed.; Academic Press: New York, 1985; Vol. 24, pp 25-111.
2. Kobayashi, J.; Ishibashi, M. In The Alkaloids; Brossi, A.; Cordell, G. A., Eds.; Academic Press: New York, 1992; Vol. 41, pp 41-124.
3. Alvarez, M.; Salas, M. Heterocycles 1991, 32, 1391-1429.
4. Faulkner, D. J. Nat. Prod. Rep. 1993, 10, 497-539.
5. Faulkner, D. J. Nat. Prod. Rep. 1992, 9, 323-364.
6. Faulkner, D. J. Nat. Prod. Rep. 1991, 5, 97-147, and previous papers in the series.
7. Fahy, E., Potts, B. C. M.; Faulkner, D. J.; Smith, K. J. Nat. Prod. 1991, 54, 564-569.
8. Dumei, E.; Andersen, R. J. J. Nat. Prod. 1992, 56, 792-796.
9. Butler, M. S.; Capon, R. J.; Lu, C. C. Aust. J. Chem. 1992, 45, 1871-1877.
10. Wright, A. E.; Pomponi, S. A.; Cross, S. S.; McCarthy, P. J. Org. Chem. 1992, 57, 4772-4775.
11. Chbani, M.; Pais, M.; Delauneux, J. M.; Debitus, C. J. Nat. Prod. 1993, 56, 99-104.
12. Bartik, K.; Braekman, J. C.; Daloze, D.; Stoller, C.; Huysecom, J.; Vandevyer, G.; Ottinger, R. Can. J. Chem. 1987, 65, 2118-2121.
13. Braekman, J. C.; Daloze, D.; Stoller, C. Bull. Soc. Chim. Belg. 1987, 96, 809-812.
14. Tsujii, S.; Rinehart, K. L., Jr.; Gunasekera, S. P.; Kashman, Y.; Cross, S. S.; Lui, M. S.; Pomponi, S. A.; Diaz, M. C. J. Org. Chem. 1988, 53, 5446-5453.
15. Morris, S. A.; Andersen, R. J. Can. J. Chem. 1989, 67, 677-681.
16. Gunasekera, S. P.; McCarthy, P. S.; Kelly-Borges, M. J. Nat. Prod. 1994, 57, 1437-1441.
17. Sakemi, S.; Sun, H. H. J. Org. Chem. 1991, 56, 4304-4307.
18. Roll, D. M.; Ireland, C. M.; Lu, H. S. M.; Clardy, J. J. Org. Chem. 1988, 53, 3276-3278.
19. After the submission, this compound was published by: Shin, J.; Seo, Y.; Cho, K. W.; Rho, J.; Sim, C. J. J. Nat. Prod. 1999, 62, 647-649.
20. Mosmann, T. J. Immunol. Methods 1983, 65, 55-68.