메뉴 건너뛰기




Volumn 12, Issue 5, 2015, Pages 813-825

Receptor-mediated endocytosis of macromolecules and strategy to enhance their transport in alveolar epithelial cells

Author keywords

Albumin; Alveolar epithelial cells; Cationic poly(amino acid)s; Clathrin; Endocytosis; Endocytosis receptor; Insulin; Intracellular trafficking; Megalin

Indexed keywords

ALBUMIN; ALBUMIN RECEPTOR; CUBILIN; INSULIN; MEGALIN; POLYLYSINE; POLYORNITHINE; PEPTIDE;

EID: 84928328494     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2015.992778     Document Type: Review
Times cited : (28)

References (115)
  • 1
    • 0343058935 scopus 로고    scopus 로고
    • Mechanisms of macromolecule absorption by the lungs
    • Patton JS. Mechanisms of macromolecule absorption by the lungs. Adv Drug Deliv Rev 1996;19:3-36
    • (1996) Adv Drug Deliv Rev , vol.19 , pp. 3-36
    • Patton, J.S.1
  • 2
    • 84902772220 scopus 로고    scopus 로고
    • Respirable nanocarriers as a promising strategy for antitubercular drug delivery
    • Mehanna MM, Mohyeldin SM, Elgindy NA. Respirable nanocarriers as a promising strategy for antitubercular drug delivery. J Control Release 2014;187:183-97
    • (2014) J Control Release , vol.187 , pp. 183-197
    • Mehanna, M.M.1    Mohyeldin, S.M.2    Elgindy, N.A.3
  • 3
    • 36249017868 scopus 로고    scopus 로고
    • Nanoparticles for drug delivery to the lungs
    • Sung JC, Pulliam BL, Edwards DA. Nanoparticles for drug delivery to the lungs. Trends Biotechnol 2007;25(12):563-70
    • (2007) Trends Biotechnol , vol.25 , Issue.12 , pp. 563-570
    • Sung, J.C.1    Pulliam, B.L.2    Edwards, D.A.3
  • 4
    • 79953902092 scopus 로고    scopus 로고
    • Reverse transcription polymerase chain reaction (RT-PCR) analysis of proteolytic enzymes in cultures of human respiratory epithelial cells
    • Baginski L, Tachon G, Falson F, et al. Reverse transcription polymerase chain reaction (RT-PCR) analysis of proteolytic enzymes in cultures of human respiratory epithelial cells. J Aerosol Med Pulm Drug Deliv 2011;24(2):89-101
    • (2011) J Aerosol Med Pulm Drug Deliv , vol.24 , Issue.2 , pp. 89-101
    • Baginski, L.1    Tachon, G.2    Falson, F.3
  • 5
    • 0026634773 scopus 로고
    • The pharmacokinetics of pulmonary-delivered insulin: A comparison of intratracheal and aerosol administration to the rabbit
    • Colthorpe P, Farr SJ, Taylor G, et al. The pharmacokinetics of pulmonary-delivered insulin: a comparison of intratracheal and aerosol administration to the rabbit. Pharm Res 1992;9(6):764-8
    • (1992) Pharm Res , vol.9 , Issue.6 , pp. 764-768
    • Colthorpe, P.1    Farr, S.J.2    Taylor, G.3
  • 6
    • 84898652900 scopus 로고    scopus 로고
    • Nanoparticle-mediated pulmonary drug delivery: A review
    • Paranjpe M, Müller-Goymann CC. Nanoparticle-mediated pulmonary drug delivery: a review. Int J Mol Sci 2014;15(4):5852-73
    • (2014) Int J Mol Sci , vol.15 , Issue.4 , pp. 5852-5873
    • Paranjpe, M.1    Müller-Goymann, C.C.2
  • 7
    • 0037952712 scopus 로고    scopus 로고
    • Targeted delivery of antiprotease to the epithelial surface of human tracheal xenografts
    • Ferkol T, Cohn LA, Phillips TE, et al. Targeted delivery of antiprotease to the epithelial surface of human tracheal xenografts. Am J Respir Crit Care Med 2003;167(10):1374-9
    • (2003) Am J Respir Crit Care Med , vol.167 , Issue.10 , pp. 1374-1379
    • Ferkol, T.1    Cohn, L.A.2    Phillips, T.E.3
  • 8
    • 1842706398 scopus 로고    scopus 로고
    • Impact of formulation and methods of pulmonary delivery on absorption of parathyroid hormone (1-34) from rat lungs
    • Codrons V, Vanderbist F, Ucakar B, et al. Impact of formulation and methods of pulmonary delivery on absorption of parathyroid hormone (1-34) from rat lungs. J Pharm Sci 2004;93(5):1241-52
    • (2004) J Pharm Sci , vol.93 , Issue.5 , pp. 1241-1252
    • Codrons, V.1    Vanderbist, F.2    Ucakar, B.3
  • 9
    • 1842789943 scopus 로고    scopus 로고
    • Pulmonary delivery of growth hormone using dry powders and visualization of its local fate in rats
    • Bosquillon C, Preat V, Vanbever R Pulmonary delivery of growth hormone using dry powders and visualization of its local fate in rats. J Control Release 2004;96(2):233-44
    • (2004) J Control Release , vol.96 , Issue.2 , pp. 233-244
    • Bosquillon, C.1    Preat, V.2    Vanbever, R.3
  • 10
    • 30544453617 scopus 로고    scopus 로고
    • Chitosan oligomers as potential and safe absorption enhancers for improving the pulmonary absorption of interferon-alpha in rats
    • Yamada K, Odomi M, Okada N, et al. Chitosan oligomers as potential and safe absorption enhancers for improving the pulmonary absorption of interferon-alpha in rats. J Pharm Sci 2005;94(11):2432-40
    • (2005) J Pharm Sci , vol.94 , Issue.11 , pp. 2432-2440
    • Yamada, K.1    Odomi, M.2    Okada, N.3
  • 11
    • 32544438613 scopus 로고    scopus 로고
    • Expression and transport functionality of FcRn within rat alveolar epithelium: A study in primary cell culture and in the isolated perfused lung
    • Sakagami M, Omidi Y, Campbell L, et al. Expression and transport functionality of FcRn within rat alveolar epithelium: a study in primary cell culture and in the isolated perfused lung. Pharm Res 2006;23(2):270-9
    • (2006) Pharm Res , vol.23 , Issue.2 , pp. 270-279
    • Sakagami, M.1    Omidi, Y.2    Campbell, L.3
  • 12
    • 79953044653 scopus 로고    scopus 로고
    • Pulmonary delivery of peptide YY for food intake suppression and reduced body weight gain in rats
    • Nadkarni PP, Costanzo RM, Sakagami M. Pulmonary delivery of peptide YY for food intake suppression and reduced body weight gain in rats. Diabetes Obes Metab 2011;13(5):408-17
    • (2011) Diabetes Obes Metab , vol.13 , Issue.5 , pp. 408-417
    • Nadkarni, P.P.1    Costanzo, R.M.2    Sakagami, M.3
  • 13
    • 84860595588 scopus 로고    scopus 로고
    • Investigations into the fate of inhaled salmon calcitonin at the respiratory epithelial barrier
    • Baginski L, Tewes F, Buckley ST, et al. Investigations into the fate of inhaled salmon calcitonin at the respiratory epithelial barrier. Pharm Res 2012;29(1):332-41
    • (2012) Pharm Res , vol.29 , Issue.1 , pp. 332-341
    • Baginski, L.1    Tewes, F.2    Buckley, S.T.3
  • 14
    • 84862684995 scopus 로고    scopus 로고
    • Vitro and in vivo characterisation of PEG-lipid-based micellar complexes of salmon calcitonin for pulmonary delivery
    • Baginski L, Gobbo OL, Tewes F, et al. In vitro and in vivo characterisation of PEG-lipid-based micellar complexes of salmon calcitonin for pulmonary delivery. Pharm Res 2012;29(6):1425-34
    • (2012) Pharm Res , vol.29 , Issue.6 , pp. 1425-1434
    • Baginski, L.1    Gobbo, O.L.2    Tewes, F.3
  • 15
    • 0035369331 scopus 로고    scopus 로고
    • Evidence for the role of alveolar epithelial gp60 in active transalveolar albumin transport in the rat lung
    • John TA, Vogel SM, Minshall RD, et al. Evidence for the role of alveolar epithelial gp60 in active transalveolar albumin transport in the rat lung. J Physiol 2001;533(Pt 2):547-59
    • (2001) J Physiol , vol.533 , pp. 547-559
    • John, T.A.1    Vogel, S.M.2    Minshall, R.D.3
  • 16
    • 33646551231 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis of FITC-albumin in alveolar type II epithelial cell line RLE-6TN
    • Yumoto R, Nishikawa H, Okamoto M, et al. Clathrin-mediated endocytosis of FITC-albumin in alveolar type II epithelial cell line RLE-6TN. Am J Physiol Lung Cell Mol Physiol 2006;290(5):L946-55
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290 , Issue.5 , pp. L946-L955
    • Yumoto, R.1    Nishikawa, H.2    Okamoto, M.3
  • 17
    • 84867473264 scopus 로고    scopus 로고
    • Megalin mediates transepithelial albumin clearance from the alveolar space of intact rabbit lungs
    • Buchäckert Y, Rummel S, Vohwinkel CU, et al. Megalin mediates transepithelial albumin clearance from the alveolar space of intact rabbit lungs. J Physiol 2012;590(Pt 20):5167-81
    • (2012) J Physiol , vol.590 , pp. 5167-5181
    • Buchäckert, Y.1    Rummel, S.2    Vohwinkel, C.U.3
  • 18
    • 0027997925 scopus 로고
    • Fate of insulin during transit across rat alveolar epithelial cell monolayers
    • Yamahara H, Verroust P, Moestrup S, et al. Fate of insulin during transit across rat alveolar epithelial cell monolayers. Eur J Pharm Biopharm 1994;40:294-8
    • (1994) Eur J Pharm Biopharm , vol.40 , pp. 294-298
    • Yamahara, H.1    Verroust, P.2    Moestrup, S.3
  • 19
    • 48149089303 scopus 로고    scopus 로고
    • Characterization of protein factor(s) in rat bronchoalveolar lavage fluid that enhance insulin transport via transcytosis across primary rat alveolar epithelial cell monolayers
    • Bahhady R, Kim KJ, Borok Z, et al. Characterization of protein factor(s) in rat bronchoalveolar lavage fluid that enhance insulin transport via transcytosis across primary rat alveolar epithelial cell monolayers. Eur J Pharm Biopharm 2008;69:808-16
    • (2008) Eur J Pharm Biopharm , vol.69 , pp. 808-816
    • Bahhady, R.1    Kim, K.J.2    Borok, Z.3
  • 20
    • 70349966123 scopus 로고    scopus 로고
    • Mechanism of insulin uptake in rat alveolar type II and type I-like epithelial cells
    • Ikehata M, Yumoto R, Kato Y, et al. Mechanism of insulin uptake in rat alveolar type II and type I-like epithelial cells. Biol Pharm Bull 2009;32(10):1765-9
    • (2009) Biol Pharm Bull , vol.32 , Issue.10 , pp. 1765-1769
    • Ikehata, M.1    Yumoto, R.2    Kato, Y.3
  • 21
    • 78650225640 scopus 로고    scopus 로고
    • The particle has landed-characterizing the fate of inhaled pharmaceuticals
    • Patton JS, Brain JD, Davies LA, et al. The particle has landed-characterizing the fate of inhaled pharmaceuticals. J Aerosol Med Pulm Drug Deliv 2010;23(Suppl 2):S71-87
    • (2010) J Aerosol Med Pulm Drug Deliv , vol.23 , pp. S71-87
    • Patton, J.S.1    Brain, J.D.2    Davies, L.A.3
  • 22
    • 0035721766 scopus 로고    scopus 로고
    • Alveolar epithelial type II cell: Defender of the alveolus revisited
    • Fehrenbach H. Alveolar epithelial type II cell: defender of the alveolus revisited. Respir Res 2001;2(1):33-46
    • (2001) Respir Res , vol.2 , Issue.1 , pp. 33-46
    • Fehrenbach, H.1
  • 23
    • 0016442807 scopus 로고
    • Transformation of alveolar type 2 cells to type 1 cells following exposure to NO2
    • Evans MJ, Cabral LJ, Stephens RJ, et al. Transformation of alveolar type 2 cells to type 1 cells following exposure to NO2. Exp Mol Pathol 1975;22(1):142-50
    • (1975) Exp Mol Pathol , vol.22 , Issue.1 , pp. 142-150
    • Evans, M.J.1    Cabral, L.J.2    Stephens, R.J.3
  • 24
    • 0030797378 scopus 로고    scopus 로고
    • Cell cycle kinetics in the alveolar epithelium
    • Uhal BD. Cell cycle kinetics in the alveolar epithelium. Am J Physiol 1997;272(6 Pt 1):L1031-45
    • (1997) Am J Physiol , vol.272 , Issue.6 , pp. L1031-L1045
    • Uhal, B.D.1
  • 25
    • 32444445050 scopus 로고    scopus 로고
    • Promotion of cell adherence and spreading: A novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type i cells
    • Demling N, Ehrhardt C, Kasper M, et al. Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells. Cell Tissue Res 2006;323(3):475-88
    • (2006) Cell Tissue Res , vol.323 , Issue.3 , pp. 475-488
    • Demling, N.1    Ehrhardt, C.2    Kasper, M.3
  • 26
    • 85047683608 scopus 로고    scopus 로고
    • RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models
    • Endter S, Francombe D, Ehrhardt C, et al. RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models. J Pharm Pharmacol 2009;61(5):583-91
    • (2009) J Pharm Pharmacol , vol.61 , Issue.5 , pp. 583-591
    • Endter, S.1    Francombe, D.2    Ehrhardt, C.3
  • 27
    • 0035132126 scopus 로고    scopus 로고
    • Localization of the peptide transporter PEPT2 in the lung: Implications for pulmonary oligopeptide uptake
    • Groneberg DA, Nickolaus M, Springer J, et al. Localization of the peptide transporter PEPT2 in the lung: implications for pulmonary oligopeptide uptake. Am J Pathol 2001;158(2):707-14
    • (2001) Am J Pathol , vol.158 , Issue.2 , pp. 707-714
    • Groneberg, D.A.1    Nickolaus, M.2    Springer, J.3
  • 28
    • 0036144689 scopus 로고    scopus 로고
    • Distribution and function of the peptide transporter PEPT2 in normal and cystic fibrosis human lung
    • Groneberg DA, Eynott PR, Doring F, et al. Distribution and function of the peptide transporter PEPT2 in normal and cystic fibrosis human lung. Thorax 2002;57(1):55-60
    • (2002) Thorax , vol.57 , Issue.1 , pp. 55-60
    • Groneberg, D.A.1    Eynott, P.R.2    Doring, F.3
  • 29
    • 84885173237 scopus 로고    scopus 로고
    • Expression and function of PEPT2 during transdifferentiation of alveolar epithelial cells
    • Takano M, Horiuchi T, Sasaki Y, et al. Expression and function of PEPT2 during transdifferentiation of alveolar epithelial cells. Life Sci 2013;93(17):630-6
    • (2013) Life Sci , vol.93 , Issue.17 , pp. 630-636
    • Takano, M.1    Horiuchi, T.2    Sasaki, Y.3
  • 30
    • 28444484982 scopus 로고    scopus 로고
    • Expression and function of efflux drug transporters in the intestine
    • Takano M, Yumoto R, Murakami T. Expression and function of efflux drug transporters in the intestine. Pharmacol Ther 2006;109(1-2):137-61
    • (2006) Pharmacol Ther , vol.109 , Issue.1-2 , pp. 137-161
    • Takano, M.1    Yumoto, R.2    Murakami, T.3
  • 31
    • 49649120671 scopus 로고    scopus 로고
    • Intestinal efflux transporters and drug absorption
    • Murakami T, Takano M. Intestinal efflux transporters and drug absorption. Expert Opin Drug Metab Toxicol 2008;4(7):923-39
    • (2008) Expert Opin Drug Metab Toxicol , vol.4 , Issue.7 , pp. 923-939
    • Murakami, T.1    Takano, M.2
  • 32
    • 0037215662 scopus 로고    scopus 로고
    • Constitutive expression of p-glycoprotein in normal lung alveolar epithelium and functionality in primary alveolar epithelial cultures
    • Campbell L, Abulrob AN, Kandalaft LE, et al. Constitutive expression of p-glycoprotein in normal lung alveolar epithelium and functionality in primary alveolar epithelial cultures. J Pharmacol Exp Ther 2003;304(1):441-52
    • (2003) J Pharmacol Exp Ther , vol.304 , Issue.1 , pp. 441-452
    • Campbell, L.1    Abulrob, A.N.2    Kandalaft, L.E.3
  • 33
    • 26244431743 scopus 로고    scopus 로고
    • ATP-binding cassette (ABC) transporters in normal and pathological lung
    • van der Deen M, de Vries EG, Timens W, et al. ATP-binding cassette (ABC) transporters in normal and pathological lung. Respir Res 2005;6:59
    • (2005) Respir Res , vol.6 , pp. 59
    • Van Der Deen, M.1    De Vries, E.G.2    Timens, W.3
  • 34
    • 33947104217 scopus 로고    scopus 로고
    • P-glycoprotein (MDR1) functional activity in human alveolar epithelial cell monolayers
    • Endter S, Becker U, Daum N, et al. P-glycoprotein (MDR1) functional activity in human alveolar epithelial cell monolayers. Cell Tissue Res 2007;328(1):77-84
    • (2007) Cell Tissue Res , vol.328 , Issue.1 , pp. 77-84
    • Endter, S.1    Becker, U.2    Daum, N.3
  • 35
    • 0025071180 scopus 로고
    • Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues
    • Cordon-Cardo C, O'Brien JP, Boccia J, et al. Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J Histochem Cytochem 1990;38(9):1277-87
    • (1990) J Histochem Cytochem , vol.38 , Issue.9 , pp. 1277-1287
    • Cordon-Cardo, C.1    O'Brien, J.P.2    Boccia, J.3
  • 36
    • 0037308144 scopus 로고    scopus 로고
    • Protein transport across the lung epithelial barrier
    • Kim KJ, Malik AB. Protein transport across the lung epithelial barrier. Am J Physiol Lung Cell Mol Physiol 2003;284(2):L247-59
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284 , Issue.2 , pp. L247-L259
    • Kim, K.J.1    Malik, A.B.2
  • 37
    • 84928340576 scopus 로고    scopus 로고
    • GP60-mediated transport of albumin in endothelial and non-endothelial cells
    • Otagiri M editor. Sojo University; Kumamoto Japan
    • Nagai J, Takano M. GP60-mediated transport of albumin in endothelial and non-endothelial cells. In: Otagiri M, editor. Human serum albumin. Sojo University; Kumamoto, Japan: 2013. p. 122-35
    • (2013) Human Serum Albumin , pp. 122-135
    • Nagai, J.1    Takano, M.2
  • 38
    • 0022204452 scopus 로고
    • Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution
    • Rennard SI, Basset G, Lecossier D, et al. Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution. J Appl Physiol 1986;60(2):532-8
    • (1986) J Appl Physiol , vol.60 , Issue.2 , pp. 532-538
    • Rennard, S.I.1    Basset, G.2    Lecossier, D.3
  • 40
    • 0022270765 scopus 로고
    • Asymmetric [14C]albumin transport across bullfrog alveolar epithelium
    • Kim KJ, LeBon TR, Shinbane JS, et al. Asymmetric [14C]albumin transport across bullfrog alveolar epithelium. J Appl Physiol 1985;59(4):1290-7
    • (1985) J Appl Physiol , vol.59 , Issue.4 , pp. 1290-1297
    • Kim, K.J.1    Lebon, T.R.2    Shinbane, J.S.3
  • 41
    • 0002820899 scopus 로고
    • Albumin interacts specifically with a 60-kDa microvascular endothelial glycoprotein
    • Schnitzer JE, Carley WW, Palade GE. Albumin interacts specifically with a 60-kDa microvascular endothelial glycoprotein. Proc Natl Acad Sci USA 1988;85(18):6773-7
    • (1988) Proc Natl Acad Sci USA , vol.85 , Issue.18 , pp. 6773-6777
    • Schnitzer, J.E.1    Carley, W.W.2    Palade, G.E.3
  • 42
    • 0027931859 scopus 로고
    • Albondin-mediated capillary permeability to albumin. Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins
    • Schnitzer JE, Oh P. Albondin-mediated capillary permeability to albumin. Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins. J Biol Chem 1994;269(8):6072-82
    • (1994) J Biol Chem , vol.269 , Issue.8 , pp. 6072-6082
    • Schnitzer, J.E.1    Oh, P.2
  • 43
    • 0030060322 scopus 로고    scopus 로고
    • Isolation and characterization of a cell surface albumin-binding protein from vascular endothelial cells
    • Tiruppathi C, Finnegan A, Malik AB. Isolation and characterization of a cell surface albumin-binding protein from vascular endothelial cells. Proc Natl Acad Sci USA 1996;93(1):250-4
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.1 , pp. 250-254
    • Tiruppathi, C.1    Finnegan, A.2    Malik, A.B.3
  • 44
    • 0030798998 scopus 로고    scopus 로고
    • Gp60 activation mediates albumin transcytosis in endothelial cells by tyrosine kinase-dependent pathway
    • Tiruppathi C, Song W, Bergenfeldt M, et al. Gp60 activation mediates albumin transcytosis in endothelial cells by tyrosine kinase-dependent pathway. J Biol Chem 1997;272(41):25968-75
    • (1997) J Biol Chem , vol.272 , Issue.41 , pp. 25968-25975
    • Tiruppathi, C.1    Song, W.2    Bergenfeldt, M.3
  • 45
    • 0035217836 scopus 로고    scopus 로고
    • Albumin uptake and transcytosis in endothelial cells in vivo induced by albumin-binding protein
    • Vogel SM, Minshall RD, Pilipović M, et al. Albumin uptake and transcytosis in endothelial cells in vivo induced by albumin-binding protein. Am J Physiol Lung Cell Mol Physiol 2001;281(6):L1512-22
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.281 , Issue.6 , pp. L1512-L1522
    • Vogel, S.M.1    Minshall, R.D.2    Pilipović, M.3
  • 46
    • 0027997787 scopus 로고
    • Filipin-sensitive caveolae-mediated transport in endothelium: Reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules
    • Schnitzer JE, Oh P, Pinney E, et al. Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules. J Cell Biol 1994;127(5):1217-32
    • (1994) J Cell Biol , vol.127 , Issue.5 , pp. 1217-1232
    • Schnitzer, J.E.1    Oh, P.2    Pinney, E.3
  • 47
    • 48249117901 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1-dependent neutrophil adhesion to endothelial cells induces caveolae-mediated pulmonary vascular hyperpermeability
    • Hu G, Vogel SM, Schwartz DE, et al. Intercellular adhesion molecule-1-dependent neutrophil adhesion to endothelial cells induces caveolae-mediated pulmonary vascular hyperpermeability. Circ Res 2008;102(12):e120-31
    • (2008) Circ Res , vol.102 , Issue.12 , pp. e120-e131
    • Hu, G.1    Vogel, S.M.2    Schwartz, D.E.3
  • 48
    • 0029102182 scopus 로고
    • Establishment of immortalized alveolar type II epithelial cell lines from adult rats
    • Driscoll KE, Carter JM, Iype PT, et al. Establishment of immortalized alveolar type II epithelial cell lines from adult rats. In Vitro Cell Dev Biol Anim 1995;31(7):516-27
    • (1995) Vitro Cell Dev Biol Anim , vol.31 , Issue.7 , pp. 516-527
    • Driscoll, K.E.1    Carter, J.M.2    Iype, P.T.3
  • 49
    • 0017275417 scopus 로고
    • A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells
    • Lieber M, Smith B, Szakal A, et al. A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. Int J Cancer 1976;17(1):62-70
    • (1976) Int J Cancer , vol.17 , Issue.1 , pp. 62-70
    • Lieber, M.1    Smith, B.2    Szakal, A.3
  • 51
    • 44349119818 scopus 로고    scopus 로고
    • Vitro cell culture models for the assessment of pulmonary drug disposition
    • Sporty JL, Horálková L, Ehrhardt C. In vitro cell culture models for the assessment of pulmonary drug disposition. Expert Opin Drug Metab Toxicol 2008;4(4):333-45
    • (2008) Expert Opin Drug Metab Toxicol , vol.4 , Issue.4 , pp. 333-345
    • Sporty, J.L.1    Horálková, L.2    Ehrhardt, C.3
  • 52
    • 43349093604 scopus 로고    scopus 로고
    • Comparison of albumin uptake in rat alveolar type II and type I-like epithelial cells in primary culture
    • Ikehata M, Yumoto R, Nakamura K, et al. Comparison of albumin uptake in rat alveolar type II and type I-like epithelial cells in primary culture. Pharm Res 2008;25(4):913-22
    • (2008) Pharm Res , vol.25 , Issue.4 , pp. 913-922
    • Ikehata, M.1    Yumoto, R.2    Nakamura, K.3
  • 53
    • 84863196831 scopus 로고    scopus 로고
    • Endocytic uptake of FITC-albumin by human alveolar epithelial cell line A549
    • Yumoto R, Suzuka S, Oda K, et al. Endocytic uptake of FITC-albumin by human alveolar epithelial cell line A549. Drug Metab Pharmacokinet 2012;27(3):336-43
    • (2012) Drug Metab Pharmacokinet , vol.27 , Issue.3 , pp. 336-343
    • Yumoto, R.1    Suzuka, S.2    Oda, K.3
  • 54
    • 81255199894 scopus 로고    scopus 로고
    • Transport of proteins and peptides and its regulation in alveolar epithelial cells
    • Takano M, Yumoto R. Transport of proteins and peptides and its regulation in alveolar epithelial cells. Membrane 2011;36:145-53
    • (2011) Membrane , vol.36 , pp. 145-153
    • Takano, M.1    Yumoto, R.2
  • 55
    • 58149288314 scopus 로고    scopus 로고
    • Low-affinity transport of FITC-albumin in alveolar type II epithelial cell line RLE-6TN
    • Tagawa M, Yumoto R, Oda K, et al. Low-affinity transport of FITC-albumin in alveolar type II epithelial cell line RLE-6TN. Drug Metab Pharmacokinet 2008;23(5):318-27
    • (2008) Drug Metab Pharmacokinet , vol.23 , Issue.5 , pp. 318-327
    • Tagawa, M.1    Yumoto, R.2    Oda, K.3
  • 56
    • 84893003657 scopus 로고    scopus 로고
    • Enhancing effect of poly(amino acid)s on albumin uptake in human lung epithelial A549 cells
    • Yumoto R, Suzuka S, Nishimoto S, et al. Enhancing effect of poly(amino acid)s on albumin uptake in human lung epithelial A549 cells. Drug Metab Pharmacokinet 2013;28:159-63
    • (2013) Drug Metab Pharmacokinet , vol.28 , pp. 159-163
    • Yumoto, R.1    Suzuka, S.2    Nishimoto, S.3
  • 57
    • 0032946360 scopus 로고    scopus 로고
    • Vacuolar and plasma membrane proton-adenosinetriphosphatases
    • Nelson N, Harvey WR. Vacuolar and plasma membrane proton-adenosinetriphosphatases. Physiol Rev 1999;79(2):361-85
    • (1999) Physiol Rev , vol.79 , Issue.2 , pp. 361-385
    • Nelson, N.1    Harvey, W.R.2
  • 58
    • 0034815934 scopus 로고    scopus 로고
    • Expression of chloride channel, ClC-5, and its role in receptor-mediated endocytosis of albumin in OK cells
    • Sasaki Y, Nagai J, Kitahara Y, et al. Expression of chloride channel, ClC-5, and its role in receptor-mediated endocytosis of albumin in OK cells. Biochem Biophys Res Commun 2001;282(1):212-18
    • (2001) Biochem Biophys Res Commun , vol.282 , Issue.1 , pp. 212-218
    • Sasaki, Y.1    Nagai, J.2    Kitahara, Y.3
  • 59
    • 4744369356 scopus 로고    scopus 로고
    • Segment-selective absorption of lysozyme in the intestine
    • Takano M, Koyama Y, Nishikawa H, et al. Segment-selective absorption of lysozyme in the intestine. Eur J Pharmacol 2004;502(1-2):149-55
    • (2004) Eur J Pharmacol , vol.502 , Issue.1-2 , pp. 149-155
    • Takano, M.1    Koyama, Y.2    Nishikawa, H.3
  • 60
    • 0034059951 scopus 로고    scopus 로고
    • Rates of protein transport across rat alveolar epithelial cell monolayers
    • Matsukawa Y, Yamahara H, Yamashita F, et al. Rates of protein transport across rat alveolar epithelial cell monolayers. J Drug Target 2000;7(5):335-42
    • (2000) J Drug Target , vol.7 , Issue.5 , pp. 335-342
    • Matsukawa, Y.1    Yamahara, H.2    Yamashita, F.3
  • 61
    • 0037372310 scopus 로고    scopus 로고
    • Absorption of intact albumin across rat alveolar epithelial cell monolayers
    • Kim KJ, Matsukawa Y, Yamahara H, et al. Absorption of intact albumin across rat alveolar epithelial cell monolayers. Am J Physiol Lung Cell Mol Physiol 2003;284(3):L458-65
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284 , Issue.3 , pp. L458-L465
    • Kim, K.J.1    Matsukawa, Y.2    Yamahara, H.3
  • 62
    • 0029028793 scopus 로고
    • The Heymann nephritis antigenic complex: Megalin (gp330) and RAP
    • Farquhar MG, Saito A, Kerjaschki D, et al. The Heymann nephritis antigenic complex: megalin (gp330) and RAP. J Am Soc Nephrol 1995;6(1):35-47
    • (1995) J Am Soc Nephrol , vol.6 , Issue.1 , pp. 35-47
    • Farquhar, M.G.1    Saito, A.2    Kerjaschki, D.3
  • 63
    • 0035006545 scopus 로고    scopus 로고
    • Megalin and cubilin: Synergistic endocytic receptors in renal proximal tubule
    • Christensen EI, Birn H. Megalin and cubilin: synergistic endocytic receptors in renal proximal tubule. Am J Physiol Renal Physiol 2001;280(4):F562-73
    • (2001) Am J Physiol Renal Physiol , vol.280 , Issue.4 , pp. F562-F573
    • Christensen, E.I.1    Birn, H.2
  • 64
    • 0035031562 scopus 로고    scopus 로고
    • Cubilin, a multifunctional epithelial receptor: An overview
    • Kozyraki R. Cubilin, a multifunctional epithelial receptor: an overview. J Mol Med (Berl) 2001;79(4):161-7
    • (2001) J Mol Med (Berl) , vol.79 , Issue.4 , pp. 161-167
    • Kozyraki, R.1
  • 65
    • 0034697043 scopus 로고    scopus 로고
    • Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins
    • Hammad SM, Barth JL, Knaak C, et al. Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins. J Biol Chem 2000;275(16):12003-8
    • (2000) J Biol Chem , vol.275 , Issue.16 , pp. 12003-12008
    • Hammad, S.M.1    Barth, J.L.2    Knaak, C.3
  • 66
    • 0029908225 scopus 로고    scopus 로고
    • Megalin/gp330 mediates uptake of albumin in renal proximal tubule
    • Cui S, Verroust P, Moestrup S, et al. Megalin/gp330 mediates uptake of albumin in renal proximal tubule. Am J Physiol 1996;271:F900-7
    • (1996) Am J Physiol , vol.271 , pp. F900-F907
    • Cui, S.1    Verroust, P.2    Moestrup, S.3
  • 67
    • 0032857025 scopus 로고    scopus 로고
    • Megalin knockout mice as an animal model of low molecular weight proteinuria
    • Leheste JR, Rolinski B, Vorum H, et al. Megalin knockout mice as an animal model of low molecular weight proteinuria. Am J Pathol 1999;155(4):1361-70
    • (1999) Am J Pathol , vol.155 , Issue.4 , pp. 1361-1370
    • Leheste, J.R.1    Rolinski, B.2    Vorum, H.3
  • 68
    • 0034073250 scopus 로고    scopus 로고
    • Cubilin is an albumin binding protein important for renal tubular albumin reabsorption
    • Birn H, Fyfe JC, Jacobsen C, et al. Cubilin is an albumin binding protein important for renal tubular albumin reabsorption. J Clin Invest 2000;105(10):1353-61
    • (2000) J Clin Invest , vol.105 , Issue.10 , pp. 1353-1361
    • Birn, H.1    Fyfe, J.C.2    Jacobsen, C.3
  • 69
    • 0035983254 scopus 로고    scopus 로고
    • HDL-holoparticle uptake by alveolar type II cells: Effect of vitamin e status
    • Kolleck I, Wissel H, Guthmann F, et al. HDL-holoparticle uptake by alveolar type II cells: effect of vitamin E status. Am J Respir Cell Mol Biol 2002;27(1):57-63
    • (2002) Am J Respir Cell Mol Biol , vol.27 , Issue.1 , pp. 57-63
    • Kolleck, I.1    Wissel, H.2    Guthmann, F.3
  • 70
    • 0037216440 scopus 로고    scopus 로고
    • Quantitative analysis of albumin uptake and transport in the rat microvessel endothelial monolayer
    • John TA, Vogel SM, Tiruppathi C, et al. Quantitative analysis of albumin uptake and transport in the rat microvessel endothelial monolayer. Am J Physiol Lung Cell Mol Physiol 2003;284(1):L187-96
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284 , Issue.1 , pp. L187-L196
    • John, T.A.1    Vogel, S.M.2    Tiruppathi, C.3
  • 71
    • 0026738318 scopus 로고
    • Membrane glycoprotein CD36: A review of its roles in adherence, signal transduction, and transfusion medicine
    • Greenwalt DE, Lipsky RH, Ockenhouse CF, et al. Membrane glycoprotein CD36: a review of its roles in adherence, signal transduction, and transfusion medicine. Blood 1992;80(5):1105-15
    • (1992) Blood , vol.80 , Issue.5 , pp. 1105-1115
    • Greenwalt, D.E.1    Lipsky, R.H.2    Ockenhouse, C.F.3
  • 72
    • 84867138330 scopus 로고    scopus 로고
    • CD36 mediates proximal tubular binding and uptake of albumin and is upregulated in proteinuric nephropathies
    • Baines RJ, Chana RS, Hall M, et al. CD36 mediates proximal tubular binding and uptake of albumin and is upregulated in proteinuric nephropathies. Am J Physiol Renal Physiol 2012;303(7):F1006-14
    • (2012) Am J Physiol Renal Physiol , vol.303 , Issue.7 , pp. F1006-F1014
    • Baines, R.J.1    Chana, R.S.2    Hall, M.3
  • 73
    • 84889052729 scopus 로고    scopus 로고
    • Albumin is recycled from the primary urine by tubular transcytosis
    • Tenten V, Menzel S, Kunter U, et al. Albumin is recycled from the primary urine by tubular transcytosis. J Am Soc Nephrol 2013;24(12):1966-80
    • (2013) J Am Soc Nephrol , vol.24 , Issue.12 , pp. 1966-1980
    • Tenten, V.1    Menzel, S.2    Kunter, U.3
  • 74
    • 4143071295 scopus 로고    scopus 로고
    • Net absorption of IgG via FcRn-mediated transcytosis across rat alveolar epithelial cell monolayers
    • Kim KJ, Fandy TE, Lee VHL, et al. Net absorption of IgG via FcRn-mediated transcytosis across rat alveolar epithelial cell monolayers. Am J Physiol Lung Cell Mol Physiol 2004;287(3):L616-22
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.287 , Issue.3 , pp. L616-L622
    • Kim, K.J.1    Fandy, T.E.2    Lee, V.H.L.3
  • 75
    • 0036300549 scopus 로고    scopus 로고
    • Lung epithelial fluid transport and the resolution of pulmonary edema
    • Matthay MA, Folkesson HG, Clerici C. Lung epithelial fluid transport and the resolution of pulmonary edema. Physiol Rev 2002;82(3):569-600
    • (2002) Physiol Rev , vol.82 , Issue.3 , pp. 569-600
    • Matthay, M.A.1    Folkesson, H.G.2    Clerici, C.3
  • 76
    • 0034993527 scopus 로고    scopus 로고
    • Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome
    • Ware LB, Matthay MA. Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2001;163(6):1376-83
    • (2001) Am J Respir Crit Care Med , vol.163 , Issue.6 , pp. 1376-1383
    • Ware, L.B.1    Matthay, M.A.2
  • 77
    • 0017649195 scopus 로고
    • Alterations of the gas exchange apparatus in adult respiratory insufficiency associated with septicemia
    • Bachofen M, Weibel ER. Alterations of the gas exchange apparatus in adult respiratory insufficiency associated with septicemia. Am Rev Respir Dis 1977;116(4):589-615
    • (1977) Am Rev Respir Dis , vol.116 , Issue.4 , pp. 589-615
    • Bachofen, M.1    Weibel, E.R.2
  • 78
    • 0028853295 scopus 로고
    • Type III procollagen peptide in the adult respiratory distress syndrome. Association of increased peptide levels in bronchoalveolar lavage fluid with increased risk for death
    • Clark JG, Milberg JA, Steinberg KP, et al. Type III procollagen peptide in the adult respiratory distress syndrome. Association of increased peptide levels in bronchoalveolar lavage fluid with increased risk for death. Ann Intern Med 1995;122(1):17-23
    • (1995) Ann Intern Med , vol.122 , Issue.1 , pp. 17-23
    • Clark, J.G.1    Milberg, J.A.2    Steinberg, K.P.3
  • 79
    • 55849114101 scopus 로고    scopus 로고
    • A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    • Eckle T, Grenz A, Laucher S, et al. A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice. J Clin Invest 2008;118(10):3301-15
    • (2008) J Clin Invest , vol.118 , Issue.10 , pp. 3301-3315
    • Eckle, T.1    Grenz, A.2    Laucher, S.3
  • 80
    • 80055114128 scopus 로고    scopus 로고
    • Phosphatidylinositol 4, 5-bisphosphate stimulates alveolar epithelial fluid clearance in male and female adult rats
    • Kooijman EE, Kuzenko SR, Gong D, et al. Phosphatidylinositol 4, 5-bisphosphate stimulates alveolar epithelial fluid clearance in male and female adult rats. Am J Physiol Lung Cell Mol Physiol 2011;301(5):L804-11
    • (2011) Am J Physiol Lung Cell Mol Physiol , vol.301 , Issue.5 , pp. L804-L811
    • Kooijman, E.E.1    Kuzenko, S.R.2    Gong, D.3
  • 81
    • 84865737204 scopus 로고    scopus 로고
    • Enhanced alveolar fluid clearance following 72 h of continuous isoproterenol infusion in rats
    • Pedersen LR, Müllertz KM, Amtorp O, et al. Enhanced alveolar fluid clearance following 72 h of continuous isoproterenol infusion in rats. Acta Physiol (Oxf) 2012;206(2):142-9
    • (2012) Acta Physiol (Oxf) , vol.206 , Issue.2 , pp. 142-149
    • Pedersen, L.R.1    Müllertz, K.M.2    Amtorp, O.3
  • 82
    • 0035142743 scopus 로고    scopus 로고
    • Spermine increases the active and passive transport across the alveolar epithelium in situ: Effect of thiol reagents
    • Saumon G, Martet G. Spermine increases the active and passive transport across the alveolar epithelium in situ: effect of thiol reagents. Pflugers Arch 2001;441(4):559-65
    • (2001) Pflugers Arch , vol.441 , Issue.4 , pp. 559-565
    • Saumon, G.1    Martet, G.2
  • 83
    • 33645974002 scopus 로고    scopus 로고
    • Novel delivery system based on complexation hydrogels as delivery vehicles for insulin-transferrin conjugates
    • Kavimandan NJ, Losi E, Peppas NA. Novel delivery system based on complexation hydrogels as delivery vehicles for insulin-transferrin conjugates. Biomaterials 2006;27(20):3846-54
    • (2006) Biomaterials , vol.27 , Issue.20 , pp. 3846-3854
    • Kavimandan, N.J.1    Losi, E.2    Peppas, N.A.3
  • 84
    • 0032710764 scopus 로고    scopus 로고
    • Proteolytic enzymes as a limitation for pulmonary absorption of insulin: In vitro and in vivo investigations
    • Shen Z, Zhang Q, Wei S, et al. Proteolytic enzymes as a limitation for pulmonary absorption of insulin: in vitro and in vivo investigations. Int J Pharm 1999;192(2):115-21
    • (1999) Int J Pharm , vol.192 , Issue.2 , pp. 115-121
    • Shen, Z.1    Zhang, Q.2    Wei, S.3
  • 85
    • 34250828002 scopus 로고    scopus 로고
    • Characterization of human insulin microcrystals and their absorption enhancement by protease inhibitors in rat lungs
    • Park SH, Kwon JH, Lim SH, et al. Characterization of human insulin microcrystals and their absorption enhancement by protease inhibitors in rat lungs. Int J Pharm 2007;339(1-2):205-12
    • (2007) Int J Pharm , vol.339 , Issue.1-2 , pp. 205-212
    • Park, S.H.1    Kwon, J.H.2    Lim, S.H.3
  • 86
    • 0043127376 scopus 로고    scopus 로고
    • Transcytosis of GCSF-transferrin across rat alveolar epithelial cell monolayers
    • Widera A, Kim KJ, Crandall ED, et al. Transcytosis of GCSF-transferrin across rat alveolar epithelial cell monolayers. Pharm Res 2003;20(8):1231-8
    • (2003) Pharm Res , vol.20 , Issue.8 , pp. 1231-1238
    • Widera, A.1    Kim, K.J.2    Crandall, E.D.3
  • 87
    • 72149095736 scopus 로고    scopus 로고
    • Human growth hormone-transferrin fusion protein for oral delivery in hypophysectomized rats
    • Amet N, Wang W, Shen WC. Human growth hormone-transferrin fusion protein for oral delivery in hypophysectomized rats. J Control Release 2010;141(2):177-82
    • (2010) J Control Release , vol.141 , Issue.2 , pp. 177-182
    • Amet, N.1    Wang, W.2    Shen, W.C.3
  • 88
    • 0025064491 scopus 로고
    • Transcellular processing of disulfide-and thioether-linked peroxidase-polylysine conjugates in cultured MDCK epithelial cells
    • Wan JS, Persiani S, Shen WC. Transcellular processing of disulfide-and thioether-linked peroxidase-polylysine conjugates in cultured MDCK epithelial cells. J Cell Physiol 1990;145(1):9-15
    • (1990) J Cell Physiol , vol.145 , Issue.1 , pp. 9-15
    • Wan, J.S.1    Persiani, S.2    Shen, W.C.3
  • 89
    • 0032810369 scopus 로고    scopus 로고
    • Screening of cationic compounds as an absorption enhancer for nasal drug delivery
    • Natsume H, Iwata S, Ohtake K, et al. Screening of cationic compounds as an absorption enhancer for nasal drug delivery. Int J Pharm 1999;185(1):1-12
    • (1999) Int J Pharm , vol.185 , Issue.1 , pp. 1-12
    • Natsume, H.1    Iwata, S.2    Ohtake, K.3
  • 90
    • 33645640345 scopus 로고    scopus 로고
    • High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression
    • Khalil IA, Kogure K, Futaki S, et al. High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression. J Biol Chem 2006;281(6):3544-51
    • (2006) J Biol Chem , vol.281 , Issue.6 , pp. 3544-3551
    • Khalil, I.A.1    Kogure, K.2    Futaki, S.3
  • 91
    • 0034605974 scopus 로고    scopus 로고
    • Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro
    • Ramsay E, Hadgraft J, Birchall J, et al. Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro. Int J Pharm 2000;210(1-2):97-107
    • (2000) Int J Pharm , vol.210 , Issue.1-2 , pp. 97-107
    • Ramsay, E.1    Hadgraft, J.2    Birchall, J.3
  • 92
    • 0035719828 scopus 로고    scopus 로고
    • The lung as a route for systemic delivery of therapeutic proteins and peptides
    • Agu RU, Ugwoke MI, Armand M, et al. The lung as a route for systemic delivery of therapeutic proteins and peptides. Respir Res 2001;2(4):198-209
    • (2001) Respir Res , vol.2 , Issue.4 , pp. 198-209
    • Agu, R.U.1    Ugwoke, M.I.2    Armand, M.3
  • 93
    • 33750343117 scopus 로고    scopus 로고
    • Efficacy and safety of inhaled insulin in the treatment of diabetes mellitus
    • de Galan BE, Simsek S, Tack CJ, et al. Efficacy and safety of inhaled insulin in the treatment of diabetes mellitus. Neth J Med 2006;64(9):319-25
    • (2006) Neth J Med , vol.64 , Issue.9 , pp. 319-325
    • De Galan, B.E.1    Simsek, S.2    Tack, C.J.3
  • 94
    • 33750724104 scopus 로고    scopus 로고
    • Clinical perspectives on pulmonary systemic and macromolecular delivery
    • Scheuch G, Kohlhaeufl MJ, Brand P, et al. Clinical perspectives on pulmonary systemic and macromolecular delivery. Adv Drug Deliv Rev 2006;58(9-10):996-1008
    • (2006) Adv Drug Deliv Rev , vol.58 , Issue.9-10 , pp. 996-1008
    • Scheuch, G.1    Kohlhaeufl, M.J.2    Brand, P.3
  • 95
    • 0036633358 scopus 로고    scopus 로고
    • New horizons-alternative routes for insulin therapy
    • Owens DR. New horizons-alternative routes for insulin therapy. Nat Rev Drug Discov 2002;1(7):529-40
    • (2002) Nat Rev Drug Discov , vol.1 , Issue.7 , pp. 529-540
    • Owens, D.R.1
  • 96
    • 1542498664 scopus 로고    scopus 로고
    • Alternative routes of insulin delivery
    • Owens DR, Zinman B, Bolli G. Alternative routes of insulin delivery. Diabet Med 2003;20(11):886-98
    • (2003) Diabet Med , vol.20 , Issue.11 , pp. 886-898
    • Owens, D.R.1    Zinman, B.2    Bolli, G.3
  • 97
    • 84928309184 scopus 로고    scopus 로고
    • FDA News Release: FDA approves Afrezza to treat diabetes
    • FDA News Release: FDA approves Afrezza to treat diabetes. Available from: www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm403122.htm
  • 98
    • 0347989344 scopus 로고    scopus 로고
    • Transport of proteins and peptides across human cultured alveolar A549 cell monolayer
    • Wang Z, Zhang Q. Transport of proteins and peptides across human cultured alveolar A549 cell monolayer. Int J Pharm 2004;269(2):451-6
    • (2004) Int J Pharm , vol.269 , Issue.2 , pp. 451-456
    • Wang, Z.1    Zhang, Q.2
  • 99
    • 33646910501 scopus 로고    scopus 로고
    • Assessment of transport rates of proteins and peptides across primary human alveolar epithelial cell monolayers
    • Bur M, Huwer H, Lehr CM, et al. Assessment of transport rates of proteins and peptides across primary human alveolar epithelial cell monolayers. Eur J Pharm Sci 2006;28(3):196-203
    • (2006) Eur J Pharm Sci , vol.28 , Issue.3 , pp. 196-203
    • Bur, M.1    Huwer, H.2    Lehr, C.M.3
  • 100
    • 45549100234 scopus 로고    scopus 로고
    • Use of Dynasore, the Small Molecule Inhibitor of Dynamin, in the Regulation of Endocytosis
    • Kirchhausen T, Macia E, Pelish H. Use of Dynasore, the Small Molecule Inhibitor of Dynamin, in the Regulation of Endocytosis. Methods Enzymol 2008;438:77-93
    • (2008) Methods Enzymol , vol.438 , pp. 77-93
    • Kirchhausen, T.1    MacIa, E.2    Pelish, H.3
  • 101
    • 81255127177 scopus 로고    scopus 로고
    • Mechanism underlying insulin uptake in alveolar epithelial cell line RLE-6TN
    • Oda K, Yumoto R, Nagai J, et al. Mechanism underlying insulin uptake in alveolar epithelial cell line RLE-6TN. Eur J Pharmacol 2011;672(1-3):62-9
    • (2011) Eur J Pharmacol , vol.672 , Issue.1-3 , pp. 62-69
    • Oda, K.1    Yumoto, R.2    Nagai, J.3
  • 102
    • 34547114456 scopus 로고    scopus 로고
    • Pathways of clathrin-independent endocytosis
    • Mayor S, Pagano RE. Pathways of clathrin-independent endocytosis. Nat Rev Mol Cell Biol 2007;8(8):603-12
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.8 , pp. 603-612
    • Mayor, S.1    Pagano, R.E.2
  • 103
    • 0031939124 scopus 로고    scopus 로고
    • Insulin receptor internalization and signalling
    • Di Guglielmo GM, Drake PG, Baass PC, et al. Insulin receptor internalization and signalling. Mol Cell Biochem 1998;182(1-2):59-63
    • (1998) Mol Cell Biochem , vol.182 , Issue.1-2 , pp. 59-63
    • Di Guglielmo, G.M.1    Drake, P.G.2    Baass, P.C.3
  • 104
    • 84871681116 scopus 로고    scopus 로고
    • Enhancement effect of poly(amino acid)s on insulin uptake in alveolar epithelial cells
    • Oda K, Yumoto R, Nagai J, et al. Enhancement effect of poly(amino acid)s on insulin uptake in alveolar epithelial cells. Drug Metab Pharmacokinet 2012;27(6):570-8
    • (2012) Drug Metab Pharmacokinet , vol.27 , Issue.6 , pp. 570-578
    • Oda, K.1    Yumoto, R.2    Nagai, J.3
  • 105
    • 0030827666 scopus 로고    scopus 로고
    • Maintenance of the differentiated type II cell phenotype by culture with an apical air surface
    • Dobbs LG, Pian MS, Maglio M, et al. Maintenance of the differentiated type II cell phenotype by culture with an apical air surface. Am J Physiol 1997;273(2 Pt 1):L347-54
    • (1997) Am J Physiol , vol.273 , Issue.2 , pp. L347-L354
    • Dobbs, L.G.1    Pian, M.S.2    Maglio, M.3
  • 106
    • 0031935246 scopus 로고    scopus 로고
    • Na+K+ATPase expression in alveolar epithelial cells: Upregulation of active ion transport by KGF
    • Borok Z, Danto SI, Dimen LL, et al. Na+K+ATPase expression in alveolar epithelial cells: upregulation of active ion transport by KGF. Am J Physiol 1998;274(1 Pt 1):L149-58
    • (1998) Am J Physiol , vol.274 , Issue.1 , pp. L149-L158
    • Borok, Z.1    Danto, S.I.2    Dimen, L.L.3
  • 107
    • 84901743670 scopus 로고    scopus 로고
    • The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier
    • Salomon JJ, Muchitsch VE, Gausterer JC, et al. The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier. Mol Pharmaceutics 2014;11(3):995-1006
    • (2014) Mol Pharmaceutics , vol.11 , Issue.3 , pp. 995-1006
    • Salomon, J.J.1    Muchitsch, V.E.2    Gausterer, J.C.3
  • 108
    • 55249118661 scopus 로고    scopus 로고
    • Immortalization of human alveolar epithelial cells to investigate nanoparticle uptake
    • Kemp SJ, Thorley AJ, Gorelik J, et al. Immortalization of human alveolar epithelial cells to investigate nanoparticle uptake. Am J Respir Cell Mol Biol 2008;39(5):591-7
    • (2008) Am J Respir Cell Mol Biol , vol.39 , Issue.5 , pp. 591-597
    • Kemp, S.J.1    Thorley, A.J.2    Gorelik, J.3
  • 109
    • 59349102492 scopus 로고    scopus 로고
    • Characterisation of the R3/1 cell line as an alveolar epithelial cell model for drug disposition studies
    • Horálková L, Radziwon A, Endter S, et al. Characterisation of the R3/1 cell line as an alveolar epithelial cell model for drug disposition studies. Eur J Pharm Sci 2009;36(4-5):444-50
    • (2009) Eur J Pharm Sci , vol.36 , Issue.4-5 , pp. 444-450
    • Horálková, L.1    Radziwon, A.2    Endter, S.3
  • 110
    • 63949085542 scopus 로고    scopus 로고
    • Inflammatory response and barrier properties of a new alveolar type 1-like cell line (TT1)
    • van den Bogaard EH, Dailey LA, Thorley AJ, et al. Inflammatory response and barrier properties of a new alveolar type 1-like cell line (TT1). Pharm Res 2009;26(5):1172-80
    • (2009) Pharm Res , vol.26 , Issue.5 , pp. 1172-1180
    • Van Den Bogaard, E.H.1    Dailey, L.A.2    Thorley, A.J.3
  • 111
    • 84925010256 scopus 로고    scopus 로고
    • Introduction of a single transporter gene ABCA3 directs RLE-6TN to more type II-like alveolar epithelial cells
    • Takano M, Yamamoto C, Sambuichi K, et al. Introduction of a single transporter gene ABCA3 directs RLE-6TN to more type II-like alveolar epithelial cells. Membrane 2013;38:246-53
    • (2013) Membrane , vol.38 , pp. 246-253
    • Takano, M.1    Yamamoto, C.2    Sambuichi, K.3
  • 112
    • 84900561248 scopus 로고    scopus 로고
    • Human podocytes perform polarized, caveolae-dependent albumin endocytosis
    • Dobrinskikh E, Okamura K, Kopp JB, et al. Human podocytes perform polarized, caveolae-dependent albumin endocytosis. Am J Physiol Renal Physiol 2014;306(9):F941-51
    • (2014) Am J Physiol Renal Physiol , vol.306 , Issue.9 , pp. F941-F951
    • Dobrinskikh, E.1    Okamura, K.2    Kopp, J.B.3
  • 113
    • 0344875494 scopus 로고    scopus 로고
    • The adaptor protein ARH escorts megalin to and through endosomes
    • Nagai M, Meerloo T, Takeda T, et al. The adaptor protein ARH escorts megalin to and through endosomes. Mol Biol Cell 2003;14(12):4984-96
    • (2003) Mol Biol Cell , vol.14 , Issue.12 , pp. 4984-4996
    • Nagai, M.1    Meerloo, T.2    Takeda, T.3
  • 114
    • 84880577418 scopus 로고    scopus 로고
    • ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression
    • Shah M, Baterina OY Jr, Taupin V, et al. ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression. J Cell Biol 2013;202(1):113-27
    • (2013) J Cell Biol , vol.202 , Issue.1 , pp. 113-127
    • Shah, M.1    Baterina, Jr.O.Y.2    Taupin, V.3
  • 115
    • 84903454260 scopus 로고    scopus 로고
    • Insulin-regulated Glut4 translocation: Membrane protein trafficking with six distinctive steps
    • Brewer PD, Habtemichael EN, Romenskaia I, et al. Insulin-regulated Glut4 translocation: membrane protein trafficking with six distinctive steps. J Biol Chem 2014;289(25):17280-98
    • (2014) J Biol Chem , vol.289 , Issue.25 , pp. 17280-17298
    • Brewer, P.D.1    Habtemichael, E.N.2    Romenskaia, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.