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Volumn 13, Issue 5, 2011, Pages 408-417

Pulmonary delivery of peptide YY for food intake suppression and reduced body weight gain in rats

Author keywords

Animal pharmacology; Antiobesity drug; Appetite control; Experimental pharmacology; Obesity therapy; Pharmacokinetics

Indexed keywords

ANOREXIGENIC AGENT; ANTIOBESITY AGENT; NEUROPEPTIDE Y; PEPTIDE YY; PEPTIDE YY [13-36]; PEPTIDE YY [3-36]; UNCLASSIFIED DRUG;

EID: 79953044653     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2011.01363.x     Document Type: Article
Times cited : (14)

References (44)
  • 1
    • 33646865736 scopus 로고    scopus 로고
    • Peptide YY(1-36) and peptide YY(3-36): part I. distribution, release and actions.
    • Ballantyne GH. Peptide YY(1-36) and peptide YY(3-36): part I. distribution, release and actions. Obes Surg 2006; 16: 651-658.
    • (2006) Obes Surg , vol.16 , pp. 651-658
    • Ballantyne, G.H.1
  • 2
    • 20444436282 scopus 로고    scopus 로고
    • Peptide YY, appetite and food intake.
    • le Roux CW, Bloom SR. Peptide YY, appetite and food intake. Proc Nutr Soc 2005; 64: 213-216.
    • (2005) Proc Nutr Soc , vol.64 , pp. 213-216
    • le Roux, C.W.1    Bloom, S.R.2
  • 3
    • 58149295547 scopus 로고    scopus 로고
    • The role of peptide YY in appetite regulation and obesity.
    • Karra E, Chandarana K, Batterham RL. The role of peptide YY in appetite regulation and obesity. J Physiol 2009; 587: 19-25.
    • (2009) J Physiol , vol.587 , pp. 19-25
    • Karra, E.1    Chandarana, K.2    Batterham, R.L.3
  • 4
    • 0037043704 scopus 로고    scopus 로고
    • Gut hormone PYY3-36 physiologically inhibits food intake.
    • Batterham RL, Cowley MA, Small CJ et al. Gut hormone PYY3-36 physiologically inhibits food intake. Nature 2002; 418: 650-654.
    • (2002) Nature , vol.418 , pp. 650-654
    • Batterham, R.L.1    Cowley, M.A.2    Small, C.J.3
  • 5
    • 0041859261 scopus 로고    scopus 로고
    • Inhibition of food intake in obese subjects by peptide YY3-36.
    • Batterham RL, Cohen MA, Ellis SM et al. Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med 2003; 349: 941-948.
    • (2003) N Engl J Med , vol.349 , pp. 941-948
    • Batterham, R.L.1    Cohen, M.A.2    Ellis, S.M.3
  • 7
    • 12344332415 scopus 로고    scopus 로고
    • Intravenous infusion of peptide YY(3-36) potently inhibits food intake in rats.
    • Chelikani PK, Haver AC, Reidelberger RD. Intravenous infusion of peptide YY(3-36) potently inhibits food intake in rats. Endocrinology 2005; 146: 879-888.
    • (2005) Endocrinology , vol.146 , pp. 879-888
    • Chelikani, P.K.1    Haver, A.C.2    Reidelberger, R.D.3
  • 8
    • 27744584314 scopus 로고    scopus 로고
    • Effect of peptide YY3336 on food intake in humans.
    • Degen L, Oesch S, Casanova M et al. Effect of peptide YY3336 on food intake in humans. Gastroenterology 2005; 129: 1430-1436.
    • (2005) Gastroenterology , vol.129 , pp. 1430-1436
    • Degen, L.1    Oesch, S.2    Casanova, M.3
  • 11
    • 34547639141 scopus 로고    scopus 로고
    • Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acid concentration in obese males.
    • Sloth B, Davidsen L, Holst JJ, Flint A, Astrup A. Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acid concentration in obese males. Am J Physiol Endocrinol Metab 2007; 293: E604-E609.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Sloth, B.1    Davidsen, L.2    Holst, J.J.3    Flint, A.4    Astrup, A.5
  • 14
    • 0030829873 scopus 로고    scopus 로고
    • Subtypes Y1 and Y2 of the neuropeptide Y receptor are respectively expressed in pro-opiomelanocortin- and neuropeptide-Y-containing neurons of the rat hypothalamic arcuate nucleus.
    • Broberger C, Landry M, Wong H, Walsh JN, Hökfelt T. Subtypes Y1 and Y2 of the neuropeptide Y receptor are respectively expressed in pro-opiomelanocortin- and neuropeptide-Y-containing neurons of the rat hypothalamic arcuate nucleus. Neuroendocrinology 1997; 66: 393-408.
    • (1997) Neuroendocrinology , vol.66 , pp. 393-408
    • Broberger, C.1    Landry, M.2    Wong, H.3    Walsh, J.N.4    Hökfelt, T.5
  • 15
    • 18044365777 scopus 로고    scopus 로고
    • Blockade of the neuropeptide Y Y2 receptor with the specific antagonist BIIE0246 attenuates the effect of endogenous and exogenous peptide YY(3-36) on food intake.
    • Abbott CR, Small CJ, Kennedy AR et al. Blockade of the neuropeptide Y Y2 receptor with the specific antagonist BIIE0246 attenuates the effect of endogenous and exogenous peptide YY(3-36) on food intake. Brain Res 2005; 1043: 139-144.
    • (2005) Brain Res , vol.1043 , pp. 139-144
    • Abbott, C.R.1    Small, C.J.2    Kennedy, A.R.3
  • 16
    • 20244369116 scopus 로고    scopus 로고
    • The role of the vagal nerve in peripheral PYY3-36-induced feeding reduction in rats.
    • Koda S, Date Y, Murakami N et al. The role of the vagal nerve in peripheral PYY3-36-induced feeding reduction in rats. Endocrinology 2005; 146: 2369-2375.
    • (2005) Endocrinology , vol.146 , pp. 2369-2375
    • Koda, S.1    Date, Y.2    Murakami, N.3
  • 17
    • 18144381593 scopus 로고    scopus 로고
    • The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway.
    • Abbott CR, Monteiro M, Small CJ et al. The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway. Brain Res 2005; 1044: 127-131.
    • (2005) Brain Res , vol.1044 , pp. 127-131
    • Abbott, C.R.1    Monteiro, M.2    Small, C.J.3
  • 18
    • 17844395786 scopus 로고    scopus 로고
    • Peripheral administration of PYY3-36 produces conditioned taste aversion in mice.
    • Halatchev IG, Cone RD. Peripheral administration of PYY3-36 produces conditioned taste aversion in mice. Cell Metab 2005; 1: 159-168.
    • (2005) Cell Metab , vol.1 , pp. 159-168
    • Halatchev, I.G.1    Cone, R.D.2
  • 19
    • 23844554610 scopus 로고    scopus 로고
    • Peripheral exendin-4 and peptide YY3-36 synergistically reduce food intake through different mechanisms in mice.
    • Talsania T, Anini Y, Siu S, Drucker DJ, Brubaker PL. Peripheral exendin-4 and peptide YY3-36 synergistically reduce food intake through different mechanisms in mice. Endocrinology 2005; 146: 3748-3756.
    • (2005) Endocrinology , vol.146 , pp. 3748-3756
    • Talsania, T.1    Anini, Y.2    Siu, S.3    Drucker, D.J.4    Brubaker, P.L.5
  • 21
    • 33750724104 scopus 로고    scopus 로고
    • Clinical perspectives on pulmonary systemic and macromolecular delivery.
    • Scheuch G, Kohlhaeufl MJ, Brand P, Siekmeier R. Clinical perspectives on pulmonary systemic and macromolecular delivery. Adv Drug Deliv Rev 2006; 58: 996-1008.
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 996-1008
    • Scheuch, G.1    Kohlhaeufl, M.J.2    Brand, P.3    Siekmeier, R.4
  • 22
    • 3142736319 scopus 로고    scopus 로고
    • Physiology: does gut hormone PYY3-36 decrease food intake in rodents?
    • Tschöp M, Castañeda TR, Joost HG et al. Physiology: does gut hormone PYY3-36 decrease food intake in rodents? Nature 2004; 430: 1-4.
    • (2004) Nature , vol.430 , pp. 1-4
    • Tschöp, M.1    Castañeda, T.R.2    Joost, H.G.3
  • 23
    • 34249862701 scopus 로고    scopus 로고
    • Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults.
    • Gantz I, Erondu N, Mallick M et al. Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults. J Clin Endocrinol Metab 2007; 92: 1754-1757.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1754-1757
    • Gantz, I.1    Erondu, N.2    Mallick, M.3
  • 24
    • 36248965689 scopus 로고    scopus 로고
    • Current challenges in non-invasive insulin delivery systems: a comparative review.
    • Khafagy El-S, Morishita M, Onuki Y, Takayama K. Current challenges in non-invasive insulin delivery systems: a comparative review. Adv Drug Deliv Rev 2007; 59: 1521-1546.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 1521-1546
    • Khafagy, E.-S.1    Morishita, M.2    Onuki, Y.3    Takayama, K.4
  • 25
    • 0022588106 scopus 로고
    • Evidence for different pre- and post-junctional receptors for neuropeptide Y and related peptides.
    • Wahlestedt C, Yanaihara N, Hakanson R. Evidence for different pre- and post-junctional receptors for neuropeptide Y and related peptides. Regul Pept 1986; 13: 307-318.
    • (1986) Regul Pept , vol.13 , pp. 307-318
    • Wahlestedt, C.1    Yanaihara, N.2    Hakanson, R.3
  • 26
    • 0024166161 scopus 로고
    • 125I-peptide YY bind to multiple receptor sites in rat brain.
    • 125I-peptide YY bind to multiple receptor sites in rat brain. Mol Pharmacol 1988; 34: 779-792.
    • (1988) Mol Pharmacol , vol.34 , pp. 779-792
    • Walker, M.W.1    Miller, R.J.2
  • 27
    • 33748110282 scopus 로고    scopus 로고
    • Neuropeptide Y induced attenuation of catecholamine synthesis in the rat mesenteric arterial bed.
    • Westfall TC, Naes L, Gardner A, Yang C-L. Neuropeptide Y induced attenuation of catecholamine synthesis in the rat mesenteric arterial bed. J Cardiovasc Pharmacol 2006; 47: 723-728.
    • (2006) J Cardiovasc Pharmacol , vol.47 , pp. 723-728
    • Westfall, T.C.1    Naes, L.2    Gardner, A.3    Yang, C.-L.4
  • 28
    • 32544444153 scopus 로고    scopus 로고
    • The importance of acclimatisation and habituation to experimental conditions when investigating the anorectic effects of gastrointestinal hormones in the rat.
    • Abbott CR, Small CJ, Sajedi A et al. The importance of acclimatisation and habituation to experimental conditions when investigating the anorectic effects of gastrointestinal hormones in the rat. Int J Obes (Lond) 2006; 30: 288-292.
    • (2006) Int J Obes (Lond) , vol.30 , pp. 288-292
    • Abbott, C.R.1    Small, C.J.2    Sajedi, A.3
  • 29
    • 0142062026 scopus 로고    scopus 로고
    • Meal pattern analysis of diet-induced obesity in susceptible and resistant rats.
    • Farley C, Cook JA, Spar BD, Austin TM, Kowalski TJ. Meal pattern analysis of diet-induced obesity in susceptible and resistant rats. Obes Res 2003; 11: 845-851.
    • (2003) Obes Res , vol.11 , pp. 845-851
    • Farley, C.1    Cook, J.A.2    Spar, B.D.3    Austin, T.M.4    Kowalski, T.J.5
  • 32
    • 0028087664 scopus 로고
    • Drug delivery via the respiratory tract.
    • Byron PR, Patton JS. Drug delivery via the respiratory tract. J Aerosol Med 1994; 7: 49-75.
    • (1994) J Aerosol Med , vol.7 , pp. 49-75
    • Byron, P.R.1    Patton, J.S.2
  • 33
    • 33845970529 scopus 로고    scopus 로고
    • Chronic PYY3-36 treatment promotes fat oxidation and ameliorates insulin resistance in C57BL6 mice.
    • van den Hoek AM, Heijboer AC, Voshol PJ et al. Chronic PYY3-36 treatment promotes fat oxidation and ameliorates insulin resistance in C57BL6 mice. Am J Physiol Endocrinol Metab 2007; 292: E238-E245.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • van den Hoek, A.M.1    Heijboer, A.C.2    Voshol, P.J.3
  • 34
    • 33846783030 scopus 로고    scopus 로고
    • Physiological evidence for the involvement of peptide YY in the regulation of energy homeostasis in humans.
    • Guo Y, Ma L, Enriori PJ et al. Physiological evidence for the involvement of peptide YY in the regulation of energy homeostasis in humans. Obesity (Silver Spring) 2006; 14: 1562-1570.
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 1562-1570
    • Guo, Y.1    Ma, L.2    Enriori, P.J.3
  • 35
    • 33748128913 scopus 로고    scopus 로고
    • Critical role for peptide YY in protein-mediated satiation and body-weight regulation.
    • Batterham RL, Heffron H, Kapoor S et al. Critical role for peptide YY in protein-mediated satiation and body-weight regulation. Cell Metab 2006; 4: 223-233.
    • (2006) Cell Metab , vol.4 , pp. 223-233
    • Batterham, R.L.1    Heffron, H.2    Kapoor, S.3
  • 36
    • 51149109600 scopus 로고    scopus 로고
    • Effects of different intermittent peptide YY (3-36) dosing strategies on food intake, body weight, and adiposity in diet-induced obese rats.
    • Reidelberger RD, Haver AC, Chelikani PK, Buescher JL. Effects of different intermittent peptide YY (3-36) dosing strategies on food intake, body weight, and adiposity in diet-induced obese rats. Am J Physiol Regul Integr Comp Physiol 2008; 295: R449-R458.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.295
    • Reidelberger, R.D.1    Haver, A.C.2    Chelikani, P.K.3    Buescher, J.L.4
  • 37
    • 36348948599 scopus 로고    scopus 로고
    • Combination therapy with amylin and peptide YY[3-36] in obese rodents: anorexigenic synergy and weight loss additivity.
    • Roth JD, Coffey T, Jodka CM et al. Combination therapy with amylin and peptide YY[3-36] in obese rodents: anorexigenic synergy and weight loss additivity. Endocrinology 2007; 148: 6054-6061.
    • (2007) Endocrinology , vol.148 , pp. 6054-6061
    • Roth, J.D.1    Coffey, T.2    Jodka, C.M.3
  • 38
    • 0035851851 scopus 로고    scopus 로고
    • The hypothalamus and the control of energy homeostasis: different circuits, different purposes.
    • Williams G, Bing C, Cai XJ, Harrold JA, King PJ, Liu XH. The hypothalamus and the control of energy homeostasis: different circuits, different purposes. Physiol Behav 2001; 74: 683-701.
    • (2001) Physiol Behav , vol.74 , pp. 683-701
    • Williams, G.1    Bing, C.2    Cai, X.J.3    Harrold, J.A.4    King, P.J.5    Liu, X.H.6
  • 40
    • 0028173653 scopus 로고
    • Two molecular forms of peptide YY (PYY) are abundant in human blood: characterization of a radioimmunoassay recognizing PYY 1-36 and PYY 3-36.
    • Grandt D, Schimiczek M, Beglinger C et al. Two molecular forms of peptide YY (PYY) are abundant in human blood: characterization of a radioimmunoassay recognizing PYY 1-36 and PYY 3-36. Regul Pept 1994; 51: 151-159.
    • (1994) Regul Pept , vol.51 , pp. 151-159
    • Grandt, D.1    Schimiczek, M.2    Beglinger, C.3
  • 42
    • 0032961015 scopus 로고    scopus 로고
    • Peptidases: structure, function and modulation of peptide-mediated effects in the human lung.
    • van der Velden VHJ, Hulsmann AR. Peptidases: structure, function and modulation of peptide-mediated effects in the human lung. Clin Exp Allergy 1999; 29: 445-456.
    • (1999) Clin Exp Allergy , vol.29 , pp. 445-456
    • van der Velden, V.H.J.1    Hulsmann, A.R.2
  • 43
    • 0027234051 scopus 로고
    • A physiological role of peptide YY on exocrine pancreatic secretion in rats.
    • Jin H, Cai L, Lee K et al. A physiological role of peptide YY on exocrine pancreatic secretion in rats. Gastroenterology 1993; 105: 208-215.
    • (1993) Gastroenterology , vol.105 , pp. 208-215
    • Jin, H.1    Cai, L.2    Lee, K.3
  • 44
    • 33750933840 scopus 로고    scopus 로고
    • Dose-dependent effects of peptide YY(3-36) on conditioned taste aversion in rats.
    • Chelikani PK, Haver AC, Reidelberger RD. Dose-dependent effects of peptide YY(3-36) on conditioned taste aversion in rats. Peptides 2006; 27: 3193-3201.
    • (2006) Peptides , vol.27 , pp. 3193-3201
    • Chelikani, P.K.1    Haver, A.C.2    Reidelberger, R.D.3


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