Mechanisms of tumor-promoting activities of nicotine in lung cancer: Synergistic effects of cell membrane and mitochondrial nicotinic acetylcholine receptors

BMC Cancer

Volumn 15, Issue 1, 2015, Pages

  Chernyavsky, Alex I ^a   Shchepotin, Igor B ^b   Galitovkiy, Valentin ^a   Grando, Sergei A ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL CANCER INSTITUTE   (Ukraine)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bronchial epithelial cells; Growth factors; Intrinsic apoptosis; Lung cancer cells; Mitochondria; Nicotinic acetylcholine receptors; Proliferation

Indexed keywords

ALPHA 3 MITOCHONDRIAL NICOTINIC ACETYLCHOLINE RECEPTOR; ALPHA 4 MITOCHONDRIAL NICOTINIC ACETYLCHOLINE RECEPTOR; ALPHA 7 MITOCHONDRIAL NICOTINIC ACETYLCHOLINE RECEPTOR; ALPHA 9 MITOCHONDRIAL NICOTINIC ACETYLCHOLINE RECEPTOR; CYTOCHROME C; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR ALPHA 3; MITOCHONDRIAL NICOTINIC ACETYLCHOLINE RECEPTOR; NICOTINE; NICOTINIC RECEPTOR; SHORT HAIRPIN RNA; SOMATOMEDIN C; UNCLASSIFIED DRUG; VASCULOTROPIN;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER GROWTH; CELL MEMBRANE; CELL PROLIFERATION; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMORTALIZED CELL LINE; LIGAND BINDING; LUNG ALVEOLUS EPITHELIUM CELL; LUNG CANCER; LUNG CARCINOGENESIS; MALIGNANT TRANSFORMATION; MITOCHONDRIAL DYNAMICS; MOLECULAR DYNAMICS; PROTEIN SECRETION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA CELL LINE; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; LUNG TUMOR; METABOLISM; MITOCHONDRION; TRANSFORMED CELL LINE; TUMOR CELL LINE;

CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LUNG NEOPLASMS; MITOCHONDRIA; NICOTINE; RECEPTORS, NICOTINIC;

EID: 84928259615     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1158-4     Document Type: Article

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