Nicotine Promotes Proliferation of Human Nasopharyngeal Carcinoma Cells by Regulating α7AChR, ERK, HIF-1α and VEGF/PEDF Signaling

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Shi, Dingbo ^a   Guo, Wei ^c   Chen, Wangbin ^a   Fu, Lingyi ^a   Wang, Jingshu ^a   Tian, Yung ^a   Xiao, Xiangsheng ^a   Kang, Tiebang ^a   Huang, Wenlin ^a,b   Deng, Wuguo ^a,b  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b State Key Laboratory of Targeted Therapy Drug of Guangdong   (China)

^c DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BUNGAROTOXIN RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINE; PIGMENT EPITHELIUM DERIVED FACTOR; SMALL INTERFERING RNA; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CANCER CELL; CANCER GROWTH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; HUMAN; HUMAN CELL; NASOPHARYNX CARCINOMA; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING;

CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; EYE PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NASOPHARYNGEAL NEOPLASMS; NERVE GROWTH FACTORS; NICOTINE; RECEPTORS, NICOTINIC; SERPINS; SIGNAL TRANSDUCTION; TIME FACTORS; TOBACCO; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

NICOTIANA TABACUM;

EID: 84865625147     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043898     Document Type: Article

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