Inhibition of nonneuronal α7-nicotinic receptor for lung cancer treatment

American Journal of Respiratory and Critical Care Medicine

Volumn 179, Issue 12, 2009, Pages 1141-1150

  Paleari, Laura ^a   Negri, Eva ^b   Catassi, Alessia ^a,c   Cilli, Michele ^a   Servent, Denis ^d   D'Angelillo, Rolando ^e   Cesario, Alfredo ^f,g   Russo, Patrizia ^a   Fini, Massimo ^g  

^a UNIVERSITY OF GENOA   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c UNIVERSITY OF INSUBRIA   (Italy)

^d SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^e UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^f CATHOLIC UNIVERSITY   (Italy)

^g IRCCS SAN RAFFAELE PISANA   (Italy)

Author keywords

7 nicotinic receptor; Antitumor activity; Apoptosis; Caspase 9; Non small cell lung cancer

Indexed keywords

BUNGAROTOXIN RECEPTOR; CISPLATIN; COBROTOXIN; PROCASPASE 9; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL XL; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; ALPHA-BUNGAROTOXIN RECEPTOR; ALPHA-COBRATOXIN; BUNGAROTOXIN; CD31 ANTIGEN; KI 67 ANTIGEN; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG RESISTANCE; DRUG SENSITIVITY; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG NON SMALL CELL CANCER; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BLOCKING; SCID MOUSE; TUMOR CELL; TUMOR XENOGRAFT; ANIMAL; APOPTOSIS; CANCER TRANSPLANTATION; CELL PROLIFERATION; COMPARATIVE STUDY; DRUG EFFECT; EXPERIMENTAL NEOPLASM; IMMUNOHISTOCHEMISTRY; LUNG TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD31; APOPTOSIS; BLOTTING, WESTERN; BUNGAROTOXINS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL PROLIFERATION; COBRA NEUROTOXIN PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; LUNG NEOPLASMS; MICE; MICE, INBRED NOD; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; NICOTINIC ANTAGONISTS; RECEPTORS, NICOTINIC;

EID: 67449105739     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200806-908OC     Document Type: Article

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